کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
977872 933218 2013 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Assessing vascular endothelial function using frequency and rank order statistics
موضوعات مرتبط
مهندسی و علوم پایه ریاضیات فیزیک ریاضی
پیش نمایش صفحه اول مقاله
Assessing vascular endothelial function using frequency and rank order statistics
چکیده انگلیسی


• Changes should appear when endothelium regulates blood vessel after occlusion.
• DM is an important contributor to atherosclerosis.
• First clinical application of FROS in assessing endothelial function in DM.

Using frequency and rank order statistics (FROS), this study analyzed the fluctuations in arterial waveform amplitudes recorded from an air pressure sensing system before and after reactive hyperemia (RH) induction by temporary blood flow occlusion to evaluate the vascular endothelial function of aged and diabetic subjects. The modified probability-weighted distance (PWD) calculated from the FROS was compared with the dilatation index (DI) to evaluate its validity and sensitivity in the assessment of vascular endothelial function. The results showed that the PWD can provide a quantitative determination of the structural changes in the arterial pressure signals associated with regulation of vascular tone and blood pressure by intact vascular endothelium after the application of occlusion stress. Our study suggests that the use of FROS is a reliable noninvasive approach to the assessment of vascular endothelial degeneration in aging and diabetes.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Physica A: Statistical Mechanics and its Applications - Volume 392, Issue 15, 1 August 2013, Pages 3122–3131
نویسندگان
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