کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9818198 | 1518777 | 2005 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Investigating the role of calcium and biological trace elements in hypericin photodynamic therapy induced tumor cell death using nuclear microscopy
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موضوعات مرتبط
مهندسی و علوم پایه
مهندسی مواد
سطوح، پوششها و فیلمها
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چکیده انگلیسی
This study involves the analysis of human NPC xenograft tumors in murine models using the National University of Singapore nuclear microscope. PDT was carried out using the photosensitiser hypericin under various conditions. The microbeam techniques of particle induced X-ray emission, Rutherford backscattering spectrometry and scanning transmission ion microscopy were used to quantify elemental concentrations in cryo-fixed sections of tumor tissue. Preliminary results are presented as well as their implications for the mechanisms underlying photodynamic cell killing.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms - Volume 231, Issues 1â4, April 2005, Pages 315-320
Journal: Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms - Volume 231, Issues 1â4, April 2005, Pages 315-320
نویسندگان
P.S.P. Thong, F. Watt, M.Q. Ren, K.C. Soo, M. Olivo,