کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9818198 1518777 2005 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Investigating the role of calcium and biological trace elements in hypericin photodynamic therapy induced tumor cell death using nuclear microscopy
موضوعات مرتبط
مهندسی و علوم پایه مهندسی مواد سطوح، پوشش‌ها و فیلم‌ها
پیش نمایش صفحه اول مقاله
Investigating the role of calcium and biological trace elements in hypericin photodynamic therapy induced tumor cell death using nuclear microscopy
چکیده انگلیسی
This study involves the analysis of human NPC xenograft tumors in murine models using the National University of Singapore nuclear microscope. PDT was carried out using the photosensitiser hypericin under various conditions. The microbeam techniques of particle induced X-ray emission, Rutherford backscattering spectrometry and scanning transmission ion microscopy were used to quantify elemental concentrations in cryo-fixed sections of tumor tissue. Preliminary results are presented as well as their implications for the mechanisms underlying photodynamic cell killing.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms - Volume 231, Issues 1–4, April 2005, Pages 315-320
نویسندگان
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