کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
98460 160538 2006 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Elevated and similar urinary testosterone/epitestosterone ratio in all samples of a competition testing: Suspicion of a manipulation
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Elevated and similar urinary testosterone/epitestosterone ratio in all samples of a competition testing: Suspicion of a manipulation
چکیده انگلیسی

The case of seven urine samples collected for anti-doping purposes during a cycling stage race with moderately elevated testosterone and epitestosterone ratio (T/E) is reported. The very low probability of having all seven urine samples with such similar elevated T/E ratio (from 3.2 to 4.7) was very suspicious. Different pattern classification tools were tested to categorize the most similar steroid profiles, but none of the models enabled a clear classification of the different urine samples. Subsequently, genetic profiling of all urine samples was performed and demonstrated that three of the seven samples were collected from the same cyclist. Finally, the International Federation confirmed DNA profiling results. This suggests that urinary steroid data using several methodologies are not appropriate for identification purposes and to an extent not unique to individuals.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Forensic Science International - Volume 163, Issues 1–2, 10 November 2006, Pages 148–151
نویسندگان
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