کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9936174 1572440 2005 12 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Reassessment of Dobutamine, Dopamine, and Milrinone in the Management of Acute Heart Failure Syndromes
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
Reassessment of Dobutamine, Dopamine, and Milrinone in the Management of Acute Heart Failure Syndromes
چکیده انگلیسی
The appropriate role of intravenous inodilator therapy (inotropic agents with vasodilator properties) in the management of acute heart failure syndromes (AHFS) has long been a subject of controversy, mainly because of the lack of prospective, placebo-controlled trials and a lack of alternative therapies. The use of intravenous inodilator infusions, however, remains common, but highly variable. As new options emerge for the treatment of AHFS, the available information should be reviewed to determine which approaches are supported by evidence, which are used empirically without evidence, and which should be considered inappropriate. For these purposes, we reviewed data available from randomized controlled trials on short-term, intermittent, and long-term use of intravenous inodilator agents (dobutamine, dopamine, and milrinone) in AHFS. Randomized controlled trials failed to show benefits with current medications and suggested that acute, intermittent, or continuous use of inodilator infusions may increase morbidity and mortality in patients with AHFS. Their use should be restricted to patients who are hypotensive as a result of low cardiac output despite a high left ventricular filling pressure.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The American Journal of Cardiology - Volume 96, Issue 6, Supplement, 19 September 2005, Pages 47-58
نویسندگان
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