Age-related changes in aortic valve with emphasis on the relation between pressure loading and thickened leaflets of the aortic valves

This study demonstrates that the prevalences of TAV and AS increase progressively with age. A greater frequency of TAV is found at the noncoronary leaflet than at either the right or left coronary leaflet. The simulated study supports our hypothesis that the noncoronary leaflet may bear a greater pressure loading than either the left or right coronary leaflet.