Keywords: ROS; reactive oxygen species; Prx; peroxiredoxin; PTP1B; protein tyrosine phosphatase 1B; PTEN; phosphatase and tensin homologue; MEFs; mouse embryonic fibroblasts; Nac; N-acetyl cysteine; GTT; glucose tolerance test; GLUT4; glucose transporter type 4; PT
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Keywords: Glucocorticoid; Non-genomic effect; Glucose uptake; C2C12 myotube; Contraction; Glut4 translocation; GCs; glucocorticoids; GRE; glucocorticoid response element; GR; glucocorticoid receptor; AMPK; 5â²-monophosphate (AMP)-activated protein kinase; CaMKII;
Keywords: 2-NBDG; 2-[N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)amino]-2-deoxy-d-glucose (metabolizable); 4-CIN; alpha-cyano-4-hydroxycinnamate; 6-NBDG; 6-[N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) amino]-2-deoxy-d-glucose; ARC; Arcuate nucleus; BBB; Blood-brain barrier; C
Keywords: 2-NBDG; 2-[N-(7-nitrobenz-2-oxa-1,3-diaxol-4-yl)amino]-2-deoxyglucose; BE; Barrett's esophagus; CLE; probe confocal laser endomicroscopy; HGD; high-grade dysplasia; IMC; intramucosal adenocarcinoma; LGD; low-grade dysplasia; OCT; optical coherence tomog
Keywords: AGEs; advanced glycation end products; LA; alpha lipoic acid; BAEC; bovine aortic endothelial cells; BCA; bicinchoninic acid; BH4; tetrahydrobiopterin; CaI; calcium ionophore; CAT; catalase (EC 1.11.1.6); CMD; cardiometabolic disease; CVD; cardiovascular
Keywords: 2-NBDG; 2-N (7-nitrobenz-2-oxa-1,3-diazol-4-yl-amino)-2-deoxyglucose; AMPK; adenosine monophosphate-activated protein kinase; BBB; blood-brain barrier; BCA; bicinchoninic acid; DAPI; 4â²-6-diamidino-2-phenylindole; DH; 1,4-dideoxy-1,4-imino-d-arabinito
Keywords: ATIC; allylisothiocyanate; GLUT4; glucose transporter 4; mtDNA; mitochondrial DNA; FFA; free fatty acid; OCR; Oxygen consumption rate; DMEM; Dulbecco's Modified Eagle's medium; FBS; fetal bovine serum; 2-NBDG; 2-[N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) amin
Keywords: Photoacoustic computed tomography; Brain imaging; 2-NBDG; Forepaw stimulation; Glucose metabolism; Hemodynamic response;
Na+, K+-ATPase Activating Antibody Displays in vitro and in vivo Beneficial Effects in the Pilocarpine Model of Epilepsy
Keywords: 2-NBDG; 2-[N-(7-nitrobenz-2-oxa-1,3-diazol-4-il)amino]-2-desoxi-d-glucose; aCSF; artificial cerebrospinal fluid; AMC; aminomethylcoumarin; FRAP; ferric-reducing antioxidant power; SE; status epilepticus; TLE; temporal lobe epilepsy; sodium pump; epilepsy;
Exercise improves glucose uptake in murine myotubes through the AMPKα2-mediated induction of Sestrins
Keywords: 2-NBDG; 2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino)-2- Deoxyglucose; 3-MA; 3-Methyladenine; ACC; Acetyl-CoA Carboxylase; Ad; adenoviruses; AKT; Protein Kinase B, also known as AKT; AMPK; Adenosine 5â²-monophosphate (AMP)-activated protein kinase; AT
Protective effects of (-)-epicatechin and the colonic metabolite 3,4-dihydroxyphenylacetic acid against glucotoxicity-induced insulin signalling blockade and altered glucose uptake and production in renal tubular NRK-52E cells
Keywords: Colonic-derived flavonoid metabolites; Epicatechin; Glucose homeostasis; Glucotoxicity; Insulin signalling pathway; NRK-52E cells; AKT/PKB; protein kinase B; AMPK; 5â²-AMP-activated protein kinase; DHBA; 2,3-dihydroxybenzoic acid; DHPAA; 3,4-dihydroxyphe
Redox signal-mediated TRPM2 promotes Ang II-induced adipocyte insulin resistance via Ca2+-dependent CaMKII/JNK cascade
Keywords: TRPM2; transient receptor potential melastatin 2; Ang II; angiotensin II; H2O2; hydrogen peroxide; ADPR; ADP-ribose; ACA; N-(p-amylcinnamoyl)anthranilic acid; NAC; N-acetylcysteine; RAS; renin-angiotensin system; AT1R; Ang II type 1 receptor blocker; ACEI
BPN, a marine-derived PTP1B inhibitor, activates insulin signaling and improves insulin resistance in C2C12 myotubes
Keywords: T2DM; type 2 diabetes mellitus; PTP1B; protein tyrosine phosphatase 1B; BPN; 3,4-dibromo-5-(2-bromo-3, 4-dihydroxy-6-(ethoxymethyl)benzyl) benzene-1,2-diol; GLUT4; glucose transporter 4 translocation; INS; insulin; IR; insulin receptor; IRS-1; IR substrat
Nutritional Intake by Ectoplasmic Nets of Schizochytrium aggregatum (Labyrinthulomycetes, Stramenopiles)
Keywords: ASW; artificial seawater; CMC; carboxymethylcellulose; EN; ectoplasmic net; EDX; energy dispersive X-ray spectrometry; EPSs; extracellular polymeric substances; FDA; fluorescein diacetate; 2-NBDG; 2-deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-D-gluc
Antidiabetic potential of the ethyl acetate extract of Physalis alkekengi and chemical constituents identified by HPLC-ESI-QTOF-MS
Keywords: EAP; ethyl acetate of aerial parts; EAF; ethyl acetate of fruit; DM; diabetes mellitus; HFD; high-fat diet; 2-NBDG; 2-[N-(7-nitrobenz-2-oxa1,3-diazol-4-yl)amino]-2-deoxy-d-glucose; 4-NPGP; 4-nitrophenyl β-d-glucopyranoside; GLUT4; glucose transporter 4;
Black bean peptides inhibit glucose uptake in Caco-2 adenocarcinoma cells by blocking the expression and translocation pathway of glucose transporters
Keywords: Phloretin: PubChem CID: 4788; Glucose: PubChem CID: 10954115; 2-NBDG PubChem CID: 6711157; A; alanine; AMPK; 5â² adenosine monophosphate-activated protein kinase; AU; arbitrary units; BPI; bean protein isolate; E; glutamic acid; F; phenylalanine; GLUT2;
Role of ABCA1 on membrane cholesterol content, insulin-dependent Akt phosphorylation and glucose uptake in adult skeletal muscle fibers from mice
Keywords: 2-NBDG; 2-[N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino]-2-deoxy-d-glucose; ABCA1; ATP binding cassette transporter A1; AMPK; AMP-activated protein kinase; DHPR; Dihydropyridine receptor; DMII; Diabetes mellitus type II; FDB; Flexor digitorum brevis; GLUT4;
ERK1/2 activated PHLPP1 induces skeletal muscle ER stress through the inhibition of a novel substrate AMPK
Keywords: 2-NBDG; 2-(N-[7-nitrobenz-2-oxa-1,3-diazol-4-yl]amino)-2-deoxyglucose; AICAR; 5-aminoimidazole-4-carboxamide-1-b-d-ribofuranoside; AMPK; AMP-activated protein kinase; AS160; Akt Substrate of 160â¯kDa; ATF4; Activating Transcription Factor 4; AUC; area un
Major constituents of Cistanche tubulosa, echinacoside and acteoside, inhibit sodium-dependent glucose cotransporter 1-mediated glucose uptake by intestinal epithelial cells
Keywords: ACT; acteoside; ECH; echinacoside; GLUT; glucose transporter; SGLT; sodium-dependent glucose cotransporter; 2-NBDG; 2-deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-d-glucose; Cistanche tubulosa; Sodium-dependent glucose cotransporter 1; Glucose uptake
Characterization of a near-infrared fluorescent DCPO-tagged glucose analogue for cancer cell imaging
Keywords: NIR; Near-infrared; 18F-FDG; 2-deoxy-2-(18F)fluoro-d-glucose; PET; positron emission tomography; 6-NBDG; 6-deoxy-N-(7-nitrobenz-2-oxa-l,3-diazol-4-yl)-aminoglucose; 2-NBDG; 2-[N-(7-nitrobenz-2-oxa-1.3-diazol-4-yl)-amino]-2-deoxyglucose; 2-DG; 2-deoxyglu
MicroRNA-712 restrains macrophage pro-inflammatory responses by targeting LRRK2 leading to restoration of insulin stimulated glucose uptake by myoblasts
Keywords: miRNA/miR; microRNA; T2D; Type 2 diabetes; IP-10; interferon-γ-inducible protein 10; FFA; free fatty acids; BMDMs; bone marrow derived macrophages; ARG-1; arginase-1; YM-1; chitinase-1; LRRK2; leucine rich repeat kinase; 2-NBDG; 2-(N-(7-nitrobenz-2-oxa-1
Ludwigia octovalvis extract improves glycemic control and memory performance in diabetic mice
Keywords: LOE; Ludwigia octovalvis extract; AMPK; AMP-activated protein kinase; STZ; streptozotocin; HFD; high fat diet; DR; dietary restriction; DMEM; Dulbecco's modified Eagle's medium; FBS; fetal bovine serum; Glut4; glucose transporter type 4; 2-NBDG; 2-(N-
SIRT6 inhibitors with salicylate-like structure show immunosuppressive and chemosensitizing effects
Keywords: SIRT6; sirtuin 6; TNF-α; tumor necrosis factor; PBMC; peripheral blood mononuclear cell; SEB; staphylococcal enterotoxin B; PMA; phorbol-12-myristate-13-acetate; 2-NBDG; 2-[N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino]-2-deoxy-d-glucose; PDAC; pancreatic d
Antioxidant/antihyperglycemic activity of phenolics from sugarcane (Saccharum officinarum L.) bagasse and identification by UHPLC-HR-TOFMS
Keywords: ROS; reactive oxygen species; 2-NBDG; 2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl) amino)-2-deoxyglucose; AKT/PKB; protein kinase B; AMPK; 5â²-AMP-activated protein kinase; GLUT-2; glucose transporter-2; Sugarcane bagasse; Phenolics; Antioxidant; Antidiabete
Evaluation of the hypoglycemic potential of a black bean hydrolyzed protein isolate and its pure peptides using in silico, in vitro and in vivo approaches
Keywords: Black bean; Hydrolyzed protein isolate; Diabetes; Glucose absorption; Glucose transporters; Hyperglycemic rats; Glibenclamide: PubChem CID: 3488.; Glucose: PubChem CID: 10954115.; Metformin: PubChem CID: 4091.; Phloretin: PubChem CID: 4788.; Streptozotoci
Mitochondrial hyperpolarization in iPSC-derived neurons from patients of FTDP-17 with 10+16 MAPT mutation leads to oxidative stress and neurodegeneration
Keywords: 2-NBDG; 2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino)-2-Deoxyglucose; AD; Alzheimer's disease; CBD; Corticobasal Degeneration; CSF; Cerebrospinal Fluid; DHE; Dihydroethidium; ETC; Electron Transport Chain; FCCP; Carbonyl cyanide-4-(trifluoromethoxy)pheny
A fluorescence method for determination of glucose transport by intestinal BBMV of common carp
Keywords: 2-NBDG; BBMV; Glucose uptake;
Hybrid drug combination: Anti-diabetic treatment of type 2 diabetic Wistar rats with combination of ellagic acid and pioglitazone
Keywords: Type 2 diabetes; Ellagic acid; Synergy; Pioglitazone; Adiponectin; BW; body weight; cDNA; complementary deoxyribonucleic acid; CT; threshold cycle; DPP-4; dipeptidyl peptidase-4; GLP-1; glucagon-like peptide-1; HDL; high density lipoprotein; H&E; hematoxy
N â 3PUFA differentially modulate palmitate-induced lipotoxicity through alterations of its metabolism in C2C12 muscle cells
Keywords: 2-NBDG; fluorescent glucose analog; ALA; alpha-linolenic acid; AMPK; AMP-activated protein kinase; AS160; AKT substrate of 160Â kDa; cpt1; carnitine palmitoyltransferase 1; DMEM; Dulbecco's modified eagle medium; DHA; docosahexaenoic acid; DPH; diphenyl-h
Elucidation of hypoglycemic action and toxicity studies of insulin-like protein from Costus igneus
Keywords: BCA; bicinchoninic acid; ILP; insulin-like protein from Costus igneus; DMEM; Dulbecco's Modified Eagle's Medium; FBS; fetal bovine serum; GLUT-4; glucose transporter-4; IR; insulin receptor; IRS-1; insulin receptor substrate-1; 2-NBDG; [2-{N-(7-nitrob
Potential antihyperglycaemic effect of myricetin derivatives from Syzygium malaccense
Keywords: 2-NBDG; 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose; AdipoQ; adiponectin, C1Q and collagen domain containing; Akt1; RAC-alpha serine/threonine-protein kinase or thymoma viral proto-oncogene 1; CAT; catalase; DM; diabetes mellitus; DIM; d
Anti-obesity effects of Asian dayflower, Commelina communis, in mice with high-fat diet-induced obesity and in 3T3-L1 cells
Keywords: C/EBP; CCAAT/enhancer-binding protein; PPAR; peroxisome proliferator-activated receptor; GLUT; glucose transporter; CCT; C.âcommunis tea; WAT; white adipose tissue; HFD; high-fat diet; LFD; low-fat diet; qPCR; quantitative PCR; TBP; TATA-binding protein
Selaginellin and biflavonoids as protein tyrosine phosphatase 1B inhibitors from Selaginella tamariscina and their glucose uptake stimulatory effects
Keywords: Selaginella tamariscina; Biflavonoids; PTP1B inhibitors; 2-NBDG;
Methylene blue-induced neuronal protective mechanism against hypoxia-reoxygenation stress
Keywords: 2-NBDG; 2-[N-(7-Nitrobenz-2-Oxa-1,3-Diazol-4-yl)Amino]-2-Deoxy-d-Glucose; ARNT; aryl hydrocarbon nuclear translocator; EDTA; ethylenediaminetetraacetic acid; EPO; erythropoietin; FBS; fetal bovine serum; G6PDH; glucose-6-phosphodehydrogenase; HEPES; 4-(2-
Saponarin activates AMPK in a calcium-dependent manner and suppresses gluconeogenesis and increases glucose uptake via phosphorylation of CRTC2 and HDAC5
Keywords: 2-NBDG; 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose; AMPK; AMP-activated protein kinase; CPT-cAMP; 8-(4-chlorophenylthio)-cAMP; CREB; cyclic AMP-responsive element-binding protein; CRTC2; CREB regulated transcription coactivator-2; ChIP;
Selective transport between heterogeneous hyphal compartments via the plasma membrane lining septal walls of Aspergillus niger
Keywords: AU; arbitrary units; FRAP; fluorescence recovery after photo-bleaching; MFS; major facilitator super-family; MM; minimal medium; 2-NBDG; 2-(N-[7-nitrobenz-2-oxa-1,3-diazol-4-yl]amino)-2-deoxyglucose; 3-OMG; 14C-3-O-methyl glucose; PC; polycarbonate; RFP;
Signals for increase of μ-opioid receptor expression in muscle by hyperglycemia
Keywords: MOR; μ-opioid receptor; STAT3; signal transducer and activator of transcription 3; STZ rats; streptozotocin-induced diabetic rats; HG; high glucose; 2-NBDG; 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose; PBS; phosphate buffer solution; RI
Phytic acid and myo-inositol support adipocyte differentiation and improve insulin sensitivity in 3T3-L1 cells
Keywords: Phytic acid; Myo-inositol; Insulin sensitivity; Adipogenesis; Glucose uptake; 3T3-L1 cells; 2-NBDG; 2-[N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino]-2-deoxy-d-glucose; ANOVA; analysis of variance; C/EBP; CCAAT/enhancer-binding protein; DMEM; Dulbecco's modi
Cocoa flavonoids attenuate high glucose-induced insulin signalling blockade and modulate glucose uptake and production in human HepG2 cells
Keywords: AKT/PKB; protein kinase B; AMPK; 5â²-AMP-activated protein kinase; BrdU; 5-bromo-2â²-deoxyuridine; CaMMK; Ca2+/calmodulin-dependent protein kinase kinase; CPE; cocoa phenolic extract; EC; (â)-epicatechin; EGCG; epigallocatechin gallate; ERK; extracell
N-glycosylation modulates the membrane sub-domain distribution and activity of glucose transporter 2 in pancreatic beta cells
Keywords: ATP; adenosine tri-phosphate; GLUT; glucose transporter; GnT; N-acetylglucosaminyltransferase; PBS; phosphate buffered saline; HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; KRH; Krebs-Ringer HEPES buffer; DTSSP; 3,3'-dithiobis[sulfosuccinim
Short communicationIn vivo imaging of epileptic activity using 2-NBDG, a fluorescent deoxyglucose analog
Keywords: Fluorescence imaging; Epileptic seizures; 2-NBDG; 4-Aminopyridine;
Original articleClinical endoscopyDiagnostic performance of two confocal endomicroscopy systems in detecting Barrett's dysplasia: a pilot study using a novel bioprobe in ex vivo tissue
Keywords: BE; Barrett's esophagus; CLE; confocal laser endomicroscopy; eCLE; endoscope-based confocal laser endomicroscopy; FIVE; fluorescence in vivo endomicroscopy; HGD; high-grade dysplasia; IMCA; intramucosal cancer; 2-NBDG; 2-[N-(7-nitrobenz-2-oxa-13-diaxol-4-
The application of 2-NBDG as a fluorescent tracer for assessing hepatic glucose production in mice during hyperinsulinemic euglycemic clamp
Keywords: Conscious mice; Hyperinsulinemic euglycemic clamp; 2-NBDG; Hepatic glucose production
Fibroblast growth factor-21 protects human skeletal muscle myotubes from palmitate-induced insulin resistance by inhibiting stress kinase and NF-κB
Keywords: NIDDM; non-insulin-dependent diabetes mellitus; FGF-21; fibroblast growth factor 21; HSMMs; human skeletal muscle myotubes; PA; palmitate; PBS; phosphate-buffered saline; 2-NBDG; 2-N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) amino-2-deoxyglucose; AMV; avian mye
Syntheses of 2-NBDG analogues for monitoring stereoselective uptake of d-glucose
Keywords: 2-NBDG; 2-NBDLG; 2-TRLG; 2-BDG; Glucose uptake; Buchwald–Hartwig reaction
High-resolution and optical molecular imaging for the early detection of colonic neoplasia
Keywords: CLE; confocal laser endomicroscopy; EC; endocytoscopy; eCLE; embedded confocal laser endomicroscopy; EGFR; epidermal growth factor receptor; LIF; laser-induced fluorescence imaging; OCT; optical coherence tomography; 2-NBDG; 2-(N-(7-nitrobenz-2-ox-1,3-dia
Utilization of fluorescence tracer in hyperinsulinemic–euglycemic clamp test in mice
Keywords: Hyperinsulinemic–euglycemic clamp test; Insulin resistance; 2-NBDG
Mapping of odor-related neuronal activity using a fluorescent derivative of glucose
Keywords: 2-NBDG; Mollusk; Olfaction; Tentacular ganglion; Oscillation
2-NBDG as a fluorescent indicator for direct glucose uptake measurement
Keywords: Diabetes; 2-NBDG; Glucose uptake;