Keywords: 3'-UTR; Dyskinesia; Parkinson's disease; Levodopa; Nitric oxide; NOS1 gene; LID; Levodopa-induced dyskinesia; PD; Parkinson's disease; MDS-UPDRS; International Parkinson and Movement Disorders Society - Unified Parkinson's Disease Rating Scale; SNP; single nucleo
مقالات ISI 3'-UTR (ترجمه نشده)
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Keywords: 3'-UTR; Oxidative stress; Ebselen; Glutathione peroxidase; Selenoprotein P; Diabetes; Differentiation; ApoER-2; apolipoprotein E receptor 2; C/EBP; CCAAT/enhancer binding protein; DIO; iodothyronine deiodinase; FoxO1a; forkhead box class O1a; GPx; glutathione per
Keywords: 3'-UTR; HGF; hepatocyte growth factor; TGFβ; transforming growth factor β; EMT; epithelial-mesenchymal transition; ET-1; Endothelin-1; MMP; metalloproteinase; Runx2; Runt-related transcription factor 2; ER; estrogen receptor; PR; progesterone receptor; HER2; ep
The mechanisms and clinical significance of PDCD4 in colorectal cancer
Keywords: 3'-UTR; Abbreviations; Full name in English; 3â²-UTR; 3â²-untranslated region; AA; asiatic acid; AOM; azoxymethane; AP-1; activating protein 1; AR; aldose reductase; ATF; activating transcription factor; Bcl-2; B-cell lymphoma 2; CAC; colitis-associated CRC; CD
Circular RNA hsa_circ_0008039 promotes breast cancer cell proliferation and migration by regulating miR-432-5p/E2F3 axis
Keywords: 3'-UTR; Hsa_circ_0008039; Breast cancer; Proliferation; Migration; Mir-432-5p; E2F3; CircRNAs; Circular RNAs; Mirnas; Micrornas; 3â²-UTR; 3â²-Untranslated Regions;
Circular RNA circMAN2B2 facilitates lung cancer cell proliferation and invasion via miR-1275/FOXK1 axis
Keywords: 3'-UTR; CircMAN2B2; Proliferation; Invasion; miR-1275; Lung cancer; FOXK1; CircRNAs; Circular RNAs; miRNAs; microRNAs; 3â²-UTR; 3â²-Untranslated Regions;
MicroRNA-613 impedes the proliferation and invasion of glioma cells by targeting cyclin-dependent kinase 14
Keywords: 3'-UTR; miRNAs; microRNAs; miR-613; microRNA-613; CDK14; cyclin-dependent kinase 14; 3â²-UTR; 3â²-untranslated region; FBS; fetal bovine serum; CCK-8; cell counting kit-8; RT-qPCR; real-time quantitative polymerase chain reaction; CDK14; Glioma; miR-613; Wnt;
MicroRNA-128 inhibits proliferation and invasion of glioma cells by targeting COX-2
Keywords: 3'-UTR; miRNA; MicroRNAs; 3â²-UTR; 3â²-untranslated region; mRNA; message RNA; WHO; World Health Organization; GBM; Glioblastoma multiforme; COX-2; cyclooxygenase-2; PGE2; prostaglandin E2; cDNA; complementary DNA; RT-qPCR; real time quantitative PCR detecting
The reciprocal link between EVI1 and miRNAs in human malignancies
Keywords: 3'-UTR; EVI1; ecotropic virus integration site-1; MiR; microRNA; 3â²-UTR; 3â²-untranslated regions; AML; acute myeloid leukemia; DNA; deoxyribonucleic acid; RNA; ribonucleic acid; NF-κβ; nuclear factor kappa β; CHIP; Chromatin Immunoprecipitation; c-Myb; c-m
MicroRNA-876-5p inhibits epithelial-mesenchymal transition and metastasis of hepatocellular carcinoma by targeting BCL6 corepressor like 1
Keywords: 3'-UTR; BCORL1; BCL6 corepressor like 1; HCC; hepatocellular carcinoma; EMT; epithelial-mesenchymal transition; miRNAs; microRNAs; TCGA; The Cancer Genome Atlas; GEO; Gene Expression Omnibus; 3â²-UTR; 3â²-untranslated region; CtBP; C-terminal Binding Protein; C
MicroRNA-543 promotes the proliferation and invasion of clear cell renal cell carcinoma cells by targeting Krüppel-like factor 6
Keywords: 3'-UTR; ccRC; Cclear cell renal cell carcinoma; CCK-8; cell counting kit-8; KLF6; Krüppel-like factor 6; miRNAs; microRNAs; miR-543; microRNA-543; 3â²-UTR; untranslated region; FBS; fetal bovine serum; RT-qPC; Rreal-time quantitative polymerase chain reaction;
Up-regulated miR-29c inhibits cell proliferation and glycolysis by inhibiting SLC2A3 expression in prostate cancer
Keywords: 3'-UTR; 3â²-UTR; 3â²-untranslated region; FBS; fetal bovine serum; GLUT3; glucose transporter type 3; HCC; hepatocellular carcinoma; Mut; mutant; NC; negative control; PCa; prostate cancer; PSA; prostate-specific antigen; qRT-PCR; quantitative real time polymer
MicroRNA-504 functions as a tumor suppressor in hepatocellular carcinoma through inhibiting Frizzled-7-mediated-Wnt/β-catenin signaling
Keywords: 3'-UTR; FZD7; Frizzled-7; HCC; hepatocellular carcinoma; mRNA; messenger RNA; miRNAs; microRNAs; miR-504; miRNA-504; CCK-8; cell counting kit-8; RT-qPCR; real-time quantitative PCR; 3â²-UTR; 3â²-untranslated region; FZD7; Hepatocellular carcinoma; miR-504; Wnt;
Obesity-induced upregulation of miR-361-5p promotes hepatosteatosis through targeting Sirt1
Keywords: 3'-UTR; 3â²-UTR; 3â²-untranslated region; Acad1; acyl-CoA dehydrogenase medium chain; Acly; ATP citrate lyase; Acox1; acyl-Coenzyme A oxidase 1; Cpt1α; carnitine palmitoyltransferase 1A; Fasn; fatty acid synthase; HFD; high fat diet; miRNA; microRNA; NAFLD; no
Study of association the single nucleotide polymorphisms (rs6631) in 3â²-UTR CGA gene with male infertility in Iranian population
Keywords: 3'-UTR; CGA; Glycoprotein hormone, alpha polypeptide gene; FSH; Follicle stimulating hormone; LH; Luteinizing hormone; TSH; Thyroid stimulating hormone; CG; Chorionic gonadotropin; SNP; Single nucleotide polymorphism; 3â²-UTR; 3´untranslated region; miRNA-bindi
Double sword role of EZH2 in leukemia
Keywords: 3'-UTR; EZH1,2; enhancer of Zeste 1 and 2; SUZ12; suppressor of zeste 12 homolog; EED; embryonic ectoderm development; AEBP2; adipocyte enhancer-binding protein 2; RBAP46/48; retinoblastoma binding proteins 46 and 48; PRC; polycomb-repressive complex; PcG; Polyco
MiR-92a regulates oral squamous cell carcinoma (OSCC) cell growth by targeting FOXP1 expression
Keywords: 3'-UTR; OSCC; oral squamous cell carcinoma; miR-92a; microRNA-92a; 3â²-UTR; 3â²-untranslated region; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; MTT; (3-[45-dimethylthiazol-2-yl]-2, 5-diphenyltetrazolium bromide); DMEM; Dulbeccoʼs modified eagleʼs medium
5-Azacytidine engages an IRE1α-EGFR-ERK1/2 signaling pathway that stabilizes the LDL receptor mRNA
Keywords: 3'-UTR; Low-density lipoprotein receptor (LDLR); Hepatocytes; 5-Azacytidine; mRNA stabilization; 3â²-UTR; AU-rich elements; IRE1α/EGFR;
MiR-320a-3p/ELF3 axis regulates cell metastasis and invasion in non-small cell lung cancer via PI3K/Akt pathway
Keywords: 3'-UTR; NSCLC; non-small cell lung cancer; miRNAs; microRNAs; 3â²-UTR; 3â²-untranslated region; ELF3; E74 like ETS transcription factor 3; miR-320a-3p; ELF3; PI3K/Akt; NSCLC;
MicroRNA-1301 inhibits migration and invasion of osteosarcoma cells by targeting BCL9
Keywords: 3'-UTR; OS; osteosarcoma; miRNAs; microRNAs; 3â²-UTR; 3â²-untranslated region; BCL9; B-cell CLL/lymphoma 9; CCK-8; cell counting kit-8; qRT-PCR; quantitative real-time PCR; SDS-PAGE; sodium dodecyl sulfate-polyacrylamide gel electrophoresis; PVDF; polyvinyliden
MiR-19a negatively regulated the expression of PTEN and promoted the growth of ovarian cancer cells
Keywords: 3'-UTR; miRNAs; microRNAs; PTEN; The phosphatase and tensin homologue deleted on chromosome ten; 3â²-UTR; 3â²-untranslated region; RT-qPCR; Reverse transcription-quantitative polymerase chain reaction; CCK-8; cell counting kit-8; RT; room temperature; ATCC; Ame
Lower miR-340 expression predicts poor prognosis of non-small cell lung cancer and promotes cell proliferation by targeting CDK4
Keywords: 3'-UTR; miRs; microRNAs; qRT-PCR; quantitative real-time PCR; 3â²-UTR; 3â²-untranslated region; NSCLC; non-small cell lung cancer; FBS; fetal bovine serum; DMEM; Dulbecco's modified Eagle medium; MircroRNA; Non-small cell lung cancer; miR-340; CDK4; Cell prolif
MiR-31 Mediates Inflammatory Signaling to Promote Re-Epithelialization during Skin Wound Healing
Keywords: 3'-UTR; 3â²-UTR; 3â²-untranslated region; Ccnd1; Cyclin D1; cKO; conditional knockout; MAPK; mitogen-activated protein kinase; PWD; post wounding; siRNA; small interfering RNA; STAT3; signal transducer and activator of transcription 3; TNF-α; tumor necrosis fa
Comprehensive and in-depth analysis of microRNA and mRNA expression profile in salivary adenoid cystic carcinoma
Keywords: 3'-UTR; SACC; salivary adenoid cystic carcinoma; 3â²-UTR; 3â²-untranslated region; DE; differentially expressed; GO; Gene ontology; Q-PCR; Quantitative real-time PCR; SCUBE3; signal peptide, CUB domain and EGF like domain containing 3; CA6; carbonic anhydrase 6
miRNAome, mRNAome and degradome analysis of Tibetan minipigs anterior pituitary
Keywords: 3'-UTR; 3â²-UTR; 3â²-untranslated region; cDNA; complementary DNA; CGA; glycoprotein hormones, alpha polypeptide; ELMO3; engulfment and cell motility 3 gene; ERAL1; Era (E. coli G-Protein Homolog)-Like 1; FSHB; follicle stimulating hormone beta subunit; GH; gro
MiR-221-3p targets ARF4 and inhibits the proliferation and migration of epithelial ovarian cancer cells
Keywords: 3'-UTR; Epithelial ovarian cancer; microRNA-221-3p; ADP-Ribosylation factor 4; Cell proliferation; Cell migration; Overall survival; EOC; epithelial ovarian cancer; miRNAs; microRNAs; mRNAs; messenger RNAs; ARF; ADP-ribosylation factor; 3â²-UTR; 3'-untranslate
Chemosensitivity of human colon cancer cells is influenced by a p53-dependent enhancement of ceramide synthase 5 and induction of autophagy
Keywords: 3'-UTR; 3â²-UTR; three prime untranslated region; 5-FU; 5-fluorouracil; ANOVA; analysis of variance; AP-1; activator protein 1; AUC; area under the curve; Cer; ceramide; CerS; ceramide synthase; CoA; coenzyme A; CQ; chloroquine; CREB; cAMP response element-bindi
New compound ChlA-F induces autophagy-dependent anti-cancer effect via upregulating Sestrin-2 in human bladder cancer
Keywords: 3'-UTR; Anchorage-independent growth; Cheliensisine A-fluoride (ChlA-F); Macro-autophagy (autophagy); miR-27a; Sestrin-2; Act D; actinomycin D; ATG; autophagy-related; BAF; bafilomycin A1; BC; bladder cancer; ChlA-F; Cheliensisine A-fluoride; CQ; chloroquine; DAP
Mitochondrial ROS-mediated post-transcriptional regulation of α-synuclein through miR-7 and miR-153
Keywords: 3'-UTR; α-SYN; alpha-synuclein; ROS; reactive oxygen species; 3â²-UTR; 3â²-untranslated region; DAT; dopamine transporter; MPP+; 1-methyl-4-phenylpyridinium; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; α-synuclein; microRNA; 3â²-UTR; Mitochondria; Pa
Case studyMantle cell lymphoma with a novel t(11;12)(q13;p11.2): a proposed alternative mechanism of CCND1 up-regulation
Keywords: 3'-UTR; Mantle cell lymphoma; CCND1; Mate-pair sequencing; Cytogenetics; Translocation; 3â²-UTR; microRNA;
Original ArticleThe tumour suppressor, miR-137, inhibits malignant melanoma migration by targetting the TBX3 transcription factor
Keywords: 3'-UTR; Malignant melanoma; miRNA replacement therapy; TBX3; miR-137; E-cadherin; 3â²-UTR; 3â² untranslated region; TCGA; the Cancer Genome Atlas; SKCM; skin cutaneous melanoma; FBS; Fetal bovine serum; miRNA; microRNA; qRT-PCR; Quantitative real time polymeras
Original ArticleThe miR-491-3p/Sp3/ABCB1 axis attenuates multidrug resistance of hepatocellular carcinoma
Keywords: 3'-UTR; Hepatocellular carcinoma; ABCB1; Sp3; miR-491-3p; Multidrug resistance; HCC; hepatocellular carcinoma; MDR; multidrug resistance; 3â²-UTR; 3â² untranslated region; NC; negative control oligonucleotides; Ctrl; control; wt; wild-type; mt; mutant;
Contributions of 5â²-UTR and 3â²-UTR cis elements to Cyt1Aa synthesis in Bacillus thuringiensis subsp. israelensis
Keywords: 3'-UTR; Bacillus thuringiensis subsp. israelensis; Promoters; Transcriptional terminator; 5â²-UTR; 3â²-UTR; cyt1Aa;
Regulatory factor X1 depresses ApoE-dependent Aβ uptake by miRNA-124 in microglial response to oxidative stress
Keywords: 3'-UTR; miR-124; RFX1; ApoE; Alzheimer's disease; Aβ uptake; 3â²-UTR; 3â²-untranslated regions; AD; Alzheimer's disease; Ago2; argonaute 2; ApoE; apolipoprotein E; Aβ; amyloid β; CCK-8; Cell Counting Kit-8; CHIP; chromatin immunoprecipitation; FBS; fetal
Genome-wide miRNA screening reveals miR-310 family members negatively regulate the immune response in Drosophila melanogaster via co-targeting Drosomycin
Keywords: 3'-UTR; miR-310 family; Innate immune response; Toll signaling; Drosomycin; Drosophila melanogaster; miRNA; microRNAs; IRR; immune response related; 3â²-UTR; 3â²-untranslated regions; AMPs; Antimicrobial peptides; small RNA-seq; small RNA deep sequencing; hpt;
Downregulation of miR-224 and let-7i contribute to cell survival and chemoresistance in chronic myeloid leukemia cells by regulating ST3GAL IV expression
Keywords: 3'-UTR; CML; chronic myeloid leukemia; BMMC; bone marrow mononuclear cells; MS; mass spectrometry; qRT-PCR; quantitative real time-PCR; ST3Gal; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase; TKIs; Tyrosine kinase inhibitors; BCRP; breast
Identification and validation of microRNAs directly regulating the UDP-glucuronosyltransferase 1A subfamily enzymes by a functional genomics approach
Keywords: 3'-UTR; UGT; UDP-glucuronosyltransferase; 3â²-UTR; 3â²-untranslated region; SNP; single nucleotide polymorphism; miRNA; microRNA; UDPGA; uridine diphosphate glucuronic acid; qPCR; quantitative real-time PCR; MRE; miRNA response element; Ez-Glu; ezetimibe glucur
Phosphorylation of poly(rC) binding protein 1 (PCBP1) contributes to stabilization of mu opioid receptor (MOR) mRNA via interaction with AU-rich element RNA-binding protein 1 (AUF1) and poly A binding protein (PABP)
Keywords: 3'-UTR; PCBP1; poly(rC) binding protein 1; MOR; mu opioid receptor; AUF1; AU-rich element RNA-binding protein 1; PABP; poly (A)-binding protein; 3â²-UTR; 3â²-untranslated region; PKA; protein kinase A; PKC; protein kinase C; CRE; C-rich element; RNA-EMSA; RNA e
Pathological and gene expression analysis of a polygenic diabetes model, NONcNZO10/LtJ mice
Keywords: 3'-UTR; T2D; type 2 diabetes; NZO/HlLt; New Zealand Obese; NON/ShiLtJ; nonobese nondiabetic; GHb; glycohemoglobin percentage; BG; blood glucose level; cDNA; complimentary DNA; AGCC; Affymetrix GeneChip Command Console Software; RMA; Robust Multiarray Average; GEO
Introduction of β-d-mannuronic acid (M2000) as a novel NSAID with immunosuppressive property based on COX-1/COX-2 activity and gene expression
Keywords: 3'-UTR; ANOVA; analysis of variance; AA; arachidonic acid; BUN; blood urea nitrogen; COX; cyclooxygenase; EAE; experimental autoimmune encephalomyelitis; IRAK1; interleukin-1 receptor-associated kinase 1; LPS; lipopolysaccharide; LPS-EB; LPS from E. coli O111: B4
LncRNA-ATB/microRNA-200a/β-catenin regulatory axis involved in the progression of HCV-related hepatic fibrosis
Keywords: 3'-UTR; 3â²-UTR; 3â²-untranslated region; α-SMA; α-smooth muscle actin; ceRNA; competing endogenous RNA; CM; conditioned media; Col1A1; alpha-1 type I collagen; ECM; extracellular matrix; EMT; epithelial-mesenchymal transition; HCV; hepatitis C virus; HCC; he
Upregulation of microRNA-574-3p in a human gastric cancer cell line AGS by TGF-β1
Keywords: 3'-UTR; miRNA; microRNA; TGF-β1; transforming growth factor-β1; Smad; mammalian homologue of Drosophila Mad and C. elegans Sma; mRISC; miRNA-induced silencing complex; EMT; epithelial-mesenchymal transformation; BSA; bovine serum albumin; NC; negative control;
Differential expression profile of miRNAs in porcine muscle and adipose tissue during development
Keywords: 3'-UTR; DE; differentially expressed; 3â²-UTR; 3â²-untranslated region; SRF; serum response factor; MyoD; myogenic differentiation; MHC-α; α-myosin heavy chain; MHC-β; β-myosin heavy chain; Myh7b; myosin heavy chain 7b; BMP2; bone morphogenetic protein 2; M
MiR-142 Is Required for Staphylococcus aureus Clearance at Skin Wound Sites via Small GTPase-Mediated Regulation of the Neutrophil Actin Cytoskeleton
Keywords: 3'-UTR; CFU; colony-forming units; EGFP; enhanced green fluorescent protein; fMLP; N-formylmethionyl-leucyl-phenylalanine; lys; lysozyme M; miRNA; microRNA; 3â²-UTR; 3â²-untranslated region; WT; wild-type;
Epigenetic silencing of miRNA-143 regulates apoptosis by targeting BCL2 in human intervertebral disc degeneration
Keywords: 3'-UTR; LBP; lower back pain; IVDD; intervertebral disc degeneration; NP; nucleus pulposus; AF; annulus fibrosus; ECM; extracellular matrix; MiRNA; microRNA; BCL2; B-cell lymphoma-2; HUST; Huazhong University of Science and Technology; IVD; intervertebral disc; M
Screening of posttranscriptional regulatory molecules of IκB-ζ
Keywords: 3'-UTR; Posttranscriptional regulation; IκB-ζ; 3â²-UTR; MyD88; AREs; Adenine and uridine-rich elements; BMDMs; Bone marrow derived macrophages (BMDMs); ELAM-1; Endothelial Leukocyte Adhesion Molecule-1; IFN; interferon; IκB; inhibitor of kappaB; IL; interleuk
Full Length ArticleDownregulation of let-7e-5p contributes to endothelial progenitor cell dysfunction in deep vein thrombosis via targeting FASLG
Keywords: 3'-UTR; EPC; endothelial progenitor cells; DVT; deep vein thrombosis; miRNA; microRNA; FASLG; Fas ligand; 3â²-UTR; 3â²-untranslated region; GFP; green fluorescent protein; IVC; inferior vena cava; Let-7e-5p; Endothelial progenitor cells; Deep vein thrombosis; F
Research reportMicroRNA-146a down-regulation correlates with neuroprotection and targets pro-apoptotic genes in cerebral ischemic injury in vitro
Keywords: 3'-UTR; miRNA; microRNA; OGD/R; oxygen-glucose deprivation and reperfusion; Bclaf1; Bcl-2-associated factor 1; qRT-PCR; quantitative real-time polymerase chain reaction; 3â²-UTR; 3â²-untranslated region; MCAO; middle cerebral artery occlusion; I/R; ischemia/rep
MicroRNA hsa-miR-25-3p suppresses the expression and drug induction of CYP2B6 in human hepatocytes
Keywords: 3'-UTR; CYP; cytochrome P450; miRNA; microRNA; DMETs; drug metabolizing enzymes and transporters; CAR; constitutive androstane receptor; PXR; pregnane X receptor; RE; response element; 3â²-UTR; 3â²-untranslated region; SULT; sulfotransferase; Ago; argonaute RIS
Transcriptome association analysis identifies miR-375 as a major determinant of variable acetaminophen glucuronidation by human liver
Keywords: 3'-UTR; ALF; acute liver failure; NAPQI; N-acetyl-p-benzoquinone imine; UGT; UDP-glucuronosyltransferase; SULT; sulfotransferase; CYP; cytochrome P450; 3â²-UTR; 3â²-untranslated region; SNP; single nucleotide polymorphism; miRNA; microRNA; UDPGA; uridine diphos