دانلود مقالات ISI درباره 4Ebp1 + ترجمه فارسی

سیگنالینگ کلسیم و پیری سلولی

Calcium signaling and cellular senescence

Keywords: 4EBP1; Eukaryotic Translation Initiation Factor 4E Binding Protein 1; ATF3; activating transcription factor 3; ATM; Ataxia Telangiectasia Mutated; ATR; Ataxia Telangiectasia and Rad3-Related; ARF; alternative reading frame; BAPTA; 1,2-bis(o-aminophenoxy)e

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

مهار رامامیسین هدف پستانداران آسیب زودرس مغز را از طریق مدولاسیون قطبش میکروگلالیال پس از خونریزی سواراخنووییدی تجربی در موش صحرایی

Inhibition of mammalian target of rapamycin attenuates early brain injury through modulating microglial polarization after experimental subarachnoid hemorrhage in rats

Keywords: mTOR; mammalian target of rapamycin; EBI; early brain injury; SAH; subarachnoid hemorrhage; SD; Sprague-Dawley; BBB; blood-brain barrier; aSAH; aneurysmal subarachnoid hemorrhage; ICP; increasing intracranial pressure; CBF; cerebral blood flow; PI3K; phos

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

محور سیگنالینگ پراکسید هیدروژن / سرامید / آکت نقش مهمی را در پتانسیل ضد لکوئمی سرگیجینال

Hydrogen peroxide/ceramide/Akt signaling axis play a critical role in the antileukemic potential of sanguinarine

Keywords: 4EBP1; eukaryotic translation initiation factor 4E-binding protein 1; aCDase; acid ceramidase; Akt; Akt/protein kinase B; aSMase; acid sphingomyelinase; CalA; calyculin A; CAPP; ceramide activated protein phosphatase; CDase; ceramidase; Cer; ceramide; Des

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2016 سفارش ترجمه

سیگنالینگ مضر در سرطان

Contextual signaling in cancer

Keywords: AKT; protein kinase B; ATF4; activating transcription factor 4; cAMP; cyclic adenosine monophosphate; CCL5; (C-C motif) ligand 5; CNS; central nervous system; 4EBP1; 4E (elF4E) binding protein; ECM; extracellular matrix; ERK; p44/p42 extracellular signal-

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2016 سفارش ترجمه

تومور سلولهای اپیتلیویید پرویوئیدی اولیه پوستی: یک بررسی مجدد بالینی و پاتولوژیک

Primary cutaneous perivascular epithelioid cell tumor: A clinicopathological and molecular reappraisal

Keywords: array-based comparative genomic hybridization; cutaneous clear cell myomelanocytic tumor; initiating mutations; mTOR pathway; perivascular epithelioid cell tumor; aCGH; array-based comparative genomic hybridization; MiTF; micro-ophthalmia-associated trans

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

فاکتور رشد مانند انسولین- 1 بیان و فعالیت گلوتاتیون پراکسیداز را در سلولهای اندوتلیال عروقی تنظیم می کند: پیامدهای فعالیت ضد آتروفی فاکتور رشد 1 انسولین

Insulin-like growth factor-1 regulates glutathione peroxidase expression and activity in vascular endothelial cells: Implications for atheroprotective actions of insulin-like growth factor-1

Keywords: hAECs; human aortic endothelial cells; oxLDL; oxidized low-density lipoprotein; nLDL; native low-density lipoprotein; GPX; glutathione peroxidase; IGF-1; insulin-like growth factor 1; Apoe; apolipoprotein e; ROS; reactive oxygen species; l-NAME; NG-nitro-

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

eIF4E Phosphorylation in Prostate Cancer

Keywords: eIF4E; eukaryotic translation initiation factor 4E; mTOR; mammalian target of rapamycin; PCa; prostate cancer; Mnk; mitogen activated protein kinase interacting protein kinase; ADT; androgen deprivation therapy; MAPK; mitogen-activated protein kinase; CRP

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Plk2 Loss Commonly Occurs in Colorectal Carcinomas but not Adenomas: Relationship to mTOR Signaling

Keywords: Plk2; Polo-like kinase 2; TSC; tuberous sclerosis complex; mTOR; mammalian target of rapamycin; p70S6K/S6K; S6: Ribosomal protein S6 kinase; AMPK; AMP-responsive protein kinase; REDD 1; regulated in DNA damage and development 1; 4EBP1; eukaryotic translat

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Correlation between telomerase and mTOR pathway in cancer stem cells

Keywords: CSCs; cancer stem cells; mTOR; mammalian target of rapamycin; PI3K; phosphoinositide 3-kinase; AKT; serine/threonine kinase 1; hTERT; human telomerase reverse transcriptase; TERC; telomerase RNA component; GBM; glioblastoma multiforme; TRF1; telomeric rep

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2018 سفارش ترجمه

Piperine potentiates curcumin-mediated repression of mTORC1 signaling in human intestinal epithelial cells: implications for the inhibition of protein synthesis and TNFα signaling

Keywords: Akt; AKT serine/threonine kinase 1; BCA; bicinchoninic acid; BRAF; B-Raf proto-oncogene, serine/threonine kinas; COX-2; cyclooxygenase-2; CUR; curcumin; CYP3A4; cytochrome P450 3A4; DMSO; dimethyl sulfoxide; DTT; dithiothreitol; eEF2; eukaryotic translati

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

Endothelial replicative senescence delayed by the inhibition of MTORC1 signaling involves MicroRNA-107

Keywords: SA-β gal; senescence-associated beta galactosidase; MTOR; mammalian target of rapamycin; 4EBP1; eIF4E binding protein 1; S6K1; S6 kinase 1; miRNA; microRNA; RISC; RNA-induced silencing complex; UTR; un-translated region; HUVEC; human umbilical vein endot

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

Binge ethanol exposure induces endoplasmic reticulum stress in the brain of adult mice

Keywords: Alcohol use isorder; Brain damage; Endoplasmic reticulum tress; mTOR signaling; Neurodegeneration; Oxidative stress; ATF6; Activating transcription factor 6; IRE1α; Inositol-requiring kinase.; PERK; Protein kinase RNA-like endoplasmic reticulum kinase.;

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

Early dietary restriction in rats alters skeletal muscle tuberous sclerosis complex, ribosomal s6 and mitogen-activated protein kinase

Keywords: Muscle, skeletal; Rats; Diet reducing; Fetal growth retardation; TOR serine-threonine kinase; Mitogen-activated protein kinase phosphatases; 4EBP1; 4E binding protein-1; AMP; adenosine monophosphate-activated protein; CON; control; eIF4E; eukaryotic tra

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2018 سفارش ترجمه

Systemic PTEN-Akt1-mTOR pathway activity in patients with normal tension glaucoma and ocular hypertension: A case series

Keywords: Normal tension glaucoma; Ocular hypertension; PTEN; Akt1; 4EBP1; S6K; mTOR; Mitochondria;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Original ArticleExpression of key mTOR pathway components in pancreatic ductal adenocarcinoma: A multicenter study for clinicopathologic and prognostic significance

Keywords: Pancreatic ductal adenocarcinoma; Prognostic factor; mTOR; 4EBP1; P70S6K; Immunohistochemistry;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Research reportInhibition of AMP-activated protein kinase alleviates focal cerebral ischemia injury in mice: Interference with mTOR and autophagy

Keywords: AMPK; AMP-activated protein kinase; Atg; autophagy related gene; DAP1; death associated protein 1; 4EBP1; eukaryotic initiation factor 4E binding protein 1; FGF; fibroblast growth factor; HIF-1; hypoxia-inducible factor-1; FIP; FAK family kinase-interacti

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Nonylphenol induced apoptosis and autophagy involving the Akt/mTOR pathway in prepubertal Sprague-Dawley male rats in vivo and in vitro

Keywords: 4EBP1; eukaryotic translation initiation factor 4E binding protein 1; ABP; androgen binding protein; DAPI; 4′-6-diamidino-2-phenylindole; DMEM; high-glucose-Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; ER; estrogen receptor; FSH; fo

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Hepatitis B virus (HBV) X protein-mediated regulation of hepatocyte metabolic pathways affects viral replication

Keywords: HBV; Hepatitis B virus; HCC; Hepatocellular carcinoma; HBx; HBV X protein; cccDNA; Covalently closed circular DNA; ORF; Open reading frame; mTORC1; Mammalian target of rapamycin (mTOR) complex 1; TSC2; Tuberous-sclerosis complex-2; AMPK; AMP-activated pro

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Interleukin-10 inhibits chronic angiotensin II-induced pathological autophagy

Keywords: NRVM; neonatal rat ventricular cardiomyocytes; Class I PI3K; class I phosphoinositide 3-kinase; 4EBP1; 4E binding protein 1; CHOP; C/EBP homologous protein; EF; ejection fraction; FS; fractional shortening; LY02; LY2940002; WT; wild-type; Autophagy; Signa

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

IGF-I and amino acids effects through TOR signaling on proliferation and differentiation of gilthead sea bream cultured myocytes

Keywords: Sparus aurata; Growth and myogenic factors; 4EBP1; 70S6K; AKT; Myocytes;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Molecular targets for cancer therapy in the PI3K/AKT/mTOR pathway

Keywords: PI3K pathway; Targeted therapy; Predictive biomarkers; 4EBP1; 4E-binding protein 1; AKT; protein kinase-B; AMPK; AMP-activated protein kinase; COSMIC; Catalogue of Somatic Mutations in Cancer; eIF4E; eukaryotic initiation factor 4E; ERK; extracellular-sig

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2014 سفارش ترجمه

PI3-kinase/Akt/mTOR signaling: Impaired on/off switches in aging, cognitive decline and Alzheimer's disease

Keywords: AD; Alzheimer's disease; Aβ; amyloid-β; APP; amyloid precursor protein; 4EBP1; eukaryotic translation initiation factor 4E (eIF-4E)-binding protein-1; FOXO; Forkhead box-O class transcription factors; FMRP; Fragile-X mental retardation protein; GSK3β;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

p70S6 kinase is a target of the novel proteasome inhibitor 3,3′-diamino-4′-methoxyflavone during apoptosis in human myeloid tumor cells

Keywords: AML; acute myeloid leukemia; DD1; 3,3′-diamino-4′-methoxyflavone; DNFAA; 2′,3-dinitroflavone-8-acetic acid; 4EBP1; eukaryotic translation initiation factor 4E binding protein 1; FCS; fetal calf serum; FITC; fluorescein isothiocyanate; LPS; lipopolys

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Activation of Gαq subunits up-regulates the expression of the tumor suppressor Fhit

Keywords: GRPR; gastrin-releasing peptide receptor; BK2R; bradykinin type 2 receptor; β2AR; β2 adrenergic receptor; MT1R; melatonin type 1 receptor; CHX; cycloheximide; eIF; eukaryotic initiation factor; 4EBP1; eIF4E binding protein 1; RGS; regulator of G protein

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2013 سفارش ترجمه

Mechanistic target of rapamycin (mTOR) dependent regulation of thioredoxin interacting protein (TXNIP) transcription in hypoxia

Keywords: Thioredoxin interacting protein; TXNIP; Mechanistic target of rapamycin; mTOR; Eukaryotic initiation factor 4E binding protein; 4EBP1; Hypoxia; Hypoxia-inducible factor; HIF

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Dysregulation of the mammalian target of rapamycin pathway in chromophobe renal cell carcinomas

Keywords: Chromophobe renal cell carcinoma; mTOR; PTEN; AKT; S6; 4EBP1; HIF-1α

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Improved Clearance during Treatment of HPV-Positive Head and Neck Cancer through mTOR Inhibition

Keywords: Ad5 E6/E7; adenovirus 5 expressing HPV-16 E6 and E7; CMI; cell-mediated immunity; CRT; cisplatin/radiation therapy; HNSCC; head and neck squamous cell carcinoma; HPV; human papillomavirus; HPV-; HPV-negative; HPV+; HPV type 16 positive; HTEs; human tonsil

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Prediction of adverse events by in vivo gene expression profiling exemplified for phytopharmaceuticals containing salicylates and the antidepressant imipramine

Keywords: 4EBP1; eukaryotic translation initiation factor 4E binding protein 1; ADRA1D; adrenergic α-1D-receptor; AE; adverse events; ACE; angiotensin I converting enzyme (peptidyl-dipeptidase A) 1; SD; Sprague-Dawley; DAG; diacylglycerol; DMARD; disease modifying

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Immunoexpression status and prognostic value of mammalian target of rapamycin and hypoxia-induced pathway members in papillary cell renal cell carcinomas

Keywords: Papillary renal cell carcinoma; mTOR; PTEN; AKT; S6; 4EBP1; HIF-1α

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

A Novel Unstructured Scaffold Based on 4EBP1 Enables the Functional Display of a Wide Range of Bioactive Peptides

Keywords: protein aptamer scaffold; 4EBP1; PCNA; cyclin; Mdm2Trx, thioredoxin A; GFP, green fluorescent protein; SBP, streptavidin-binding peptide; PCNA, proliferating cell nuclear antigen; WT, wild type; β-gal, β-galactosidase; CBD, cyclin-binding domain; Cdk, cyc

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2010 سفارش ترجمه

Deregulation of mTOR signaling is involved in thymic lymphoma development in Atm−/− mice

Keywords: A-T; ATM; Thymocyte; Thymic lymphoma; c-Myc; mTOR; 4EBP1; Cyclin D1

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Chemopreventive efficacy of rapamycin on Peutz–Jeghers syndrome in a mouse model

Keywords: Peutz–Jeghers syndrome; LKB1; Polyposis; Rapamycin; S6; 4EBP1

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Bevacizumab and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma

Keywords: HCC; Hepatocellular carcinoma; VEGF; vascular endothelial growth factor; BEV; Bevacizumab; mTOR; mammalian target-of-rapamycin; p70S6K; p70S6 kinase; RPS6; ribosomal S6 protein; 4EBP1; eukaryotic initiation factor 4E-binding protein 1; RAPA; rapamycin; IP

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

ABT-869, a multi-targeted tyrosine kinase inhibitor, in combination with rapamycin is effective for subcutaneous hepatocellular carcinoma xenograft

Keywords: HCC; hepatocellular carcinoma; RTKIs; tyrosine kinase inhibitors; MAPK; mitogen activated protein kinase; VEGF; vascular endothelial growth factor; mTOR; mammalian target of rapamycin; p70S6K; p70S6 kinase; 4EBP1; eukaryotic initiation factor 4E-binding p

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2008 سفارش ترجمه

Disruption of Parallel and Converging Signaling Pathways Contributes to the Synergistic Antitumor Effects of Simultaneous mTOR and EGFR Inhibition in GBM Cells

Keywords: epidermal growth factor receptor; signal transduction; rapamycin; glioblastoma; 4EBP1; AM;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه