Keywords: 5-HT1A; serotonin 1A receptor; AE; adverse events; AIDS; acquired immunodeficiency syndrome; CB1; cannabinoid-one receptor; CB2; cannabinoid-two receptor; CBD; cannabidiol; CBDA; cannabidiolic acid; CRISP-R; Clustered Regularly Interspaced Short Palindrom
مقالات ISI (ترجمه نشده)
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Keywords: Fetal alcohol spectrum disorder; Epilepsy; Neural stem cells; GABA; Teratogenecity; Alcohol; Neurodegeneration; Transplantation; 5-HT1A; Serotonin receptor; 5-HTP; 5-hydroxytryptophan; AEDs; anti-epileptic drugs; ADHD; attention deficit hyperactivity diso
Keywords: Vortioxetine (PubChem CID 9966051); Paroxetine (Pubmed CID 43815); 8-OH-DPAT (PubChem CID 1220); Flesinoxan (PubChem CID 57347); CP-94253 (PubChem CID 4029677); Ondansetron (PubChem CID 4595); Vortioxetine; 5-HT1A; 5-HT1B; 5-HT3; Male rat sexual behavior;
Keywords: Dopamine; Serotonin; Multireceptor; Atypical antipsychotic; 5-HT1A;
Keywords: 5-HIAA; 5-hydroxyindoleacetic acid; 5-HT; 5-hydroxytryptamine; 5-HTT; 5-HT transporter; BCAAs; Branched-chain amino acids; CNS; central nervous system; HPLC-MS; high-performance liquid chromatography-mass spectrometry; exercise-induced chronic fatigue; tr
Keywords: ACTH; adrenocorticotropic hormone; CA; central area; CA1; cornus ammonis 1 layer; CNS; central nervous system; CORT; corticosterone; DIG; digoxigenin; DSS; dextran sodium sulfate; ELISA; enzyme-linked immunosorbent assay; EPM; elevated plus maze; GPCR; G
Keywords: D2; 5-HT1A; 5-HT2A; PCP-induced hyperactivity; Catalepsy
Keywords: % OAE; percentage of open arm entries; % OAT; percentage of time spent on the open arms; 5-HT1A; 5-hydroxytryptamine 1A; BrdU; bromodeoxyuridine; CBD; cannabidiol; CNS; central nervous system; CUS; chronic unpredictable stress; DAB; 3-3'-diamino-benzidi
Keywords: 5-HT, 5-hydroxytryptamine serotonin; DA, dopamine; NE, norepinephrine; SERT, serotonin transporter; TPH2, tryptophan hydroxylase 2; VMAT2, vesicular monoamine transporter 2Serotonin; VMAT2; Synaptic vesicle; Dorsal raphe; Parkinson's disease; 5-HT1A; 5-HT
Keywords: Zinc; Zn transporters; Suicide; Major depressive disorder; Glutamate receptors; 5-HT1A;
Keywords: 5-HT1A; 5-hydroxytryptamine-1A receptor; BDNF; brain-derived neurotrophic factor; CMS; chronic mild stress; CRH; corticotropin-releasing hormone; CRH-R1; corticotropin-releasing hormone receptor-1; DFP; diisopropyl fluorophosphates; DSM-5; Diagnostic and
Keywords: Antidepressant; Benzoxazole/benzothiazole; 2,3-Dihydrobenzo[b][1,4]dioxine; 5-HT1A; 5-HT2A;
Keywords: 5-HT; 5-hydroxytryptamine; 5-HT1A; 5-hydroxytryptamine1A; 5-HT3; 5-hydroxytryptamine3; CBD; cannabidiol; CBDA; cannabidiolic acid; D2; dopamine2; DA; dopamine; i.p.; intraperitoneally; i.v.; intravenously; LiCl; lithium chloride; MCP; metoclopramide; OND;
Keywords: mPFC; medial prefrontal cortex; ACC; anterior cingulate cortex; DG; dentate gyrus; NAc; nucleus accumbens; AMPAR; α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor; NMDAR; N-methyl-d-aspartic acid receptor; VDCC; voltage-dependent calcium ch
Synthesis and antidepressant activity of a series of arylalkanol and aralkyl piperazine derivatives targeting SSRI/5-HT1A/5-HT7
Keywords: Antidepressant; Arylalkanol and aralkyl piperazine; SSRI; 5-HT1A; 5-HT7;
Ziziphus spinosa seeds for insomnia: A review of chemistry and psychopharmacology
Keywords: Ziziphus spinosa; Zizyphus; Suan zao ren; Insomnia; Phytochemical; Psychopharmacology; 5-HT1A; 5-Hydroxytryptamine-1A; α1; alpha-one; α5; alpha-five; ADMET; absorption, distribution, metabolism, excretion, and toxicity; CNS; central nervous system; CPA;
Estrogen receptor β deficiency impairs BDNF-5-HT2A signaling in the hippocampus of female brain: A possible mechanism for menopausal depression
Keywords: Menopausal depression; Estrogen receptor β (ERβ); Brain-derived neurotrophic factor (BDNF); 5-HT1A; 5-HT2A; Hippocampus;
Cannabidiol reduces neuroinflammation and promotes neuroplasticity and functional recovery after brain ischemia
Keywords: 5-HT1A; 5-hydroxytryptamine 1A; BCCAO; bilateral common carotid artery occlusion; BDNF; brain derived neurotrophic factor; CB1 and CB2; types 1 and 2 cannabinoid receptors; CBD; cannabidiol; DCX; doublecortin; DG; dentate gyrus; EZM; elevated zero maze; F
Serotonin and urocortin 1 in the dorsal raphe and Edinger-Westphal nuclei after early life stress in serotonin transporter knockout rats
Keywords: 5-HT; 5-hydroxytryptamine, serotonin; 5-HT1A; 5-HT receptor 1A; 5-HTT; 5-HT transporter; 5-HTTLPR; 5-HT transporter-linked polymorphic region; CpG; cytosine-phosphate-guanine; CRE; cyclic-AMP response element; CRF; corticotropin-releasing factor; CRF1R; c
Neurochemical and behavioral studies on the 5-HT1A-dependent antipsychotic action of the mGlu4 receptor agonist LSP4-2022
Keywords: Glutamate; Serotonin; Dopamine; GABA; mGlu; 5-HT1A; Schizophrenia;
Association study of 5-HT1A, 5-HT2A polymorphisms with schizophrenia and major depressive disorder in the Han Chinese population
Keywords: Association; 5-HT1A; 5-HT2A; Schizophrenia; Major depressive disorder;
18F-FCWAY, a serotonin 1A receptor radioligand, is a substrate for efflux transport at the human blood-brain barrier
Keywords: PET; Efflux transporter; P-gp; Blood brain barrier; 5-HT1A;
Genetic polymorphisms of serotonin transporter and receptor 1A could influence success during embryo implantation and maintenance of pregnancy
Keywords: 5-HTTLPR; 5-HT1A; polymorphism; biochemical pregnancy loss; serotonin;
17β-Estradiol augments antidepressant efficacy of escitalopram in ovariectomized rats: Neuroprotective and serotonin reuptake transporter modulatory effects
Keywords: 5-HT1A; serotonin receptor 1A; SERT; serotonin reuptake transporter; ERα, ERβ; estrogen receptors alpha and beta; BDNF; brain-derived neurotrophic factor; AchE; acetylcholinestearase; TNF-α; tumor necrosis factor-alpha; MWM; Morris water maze; FST; for
Disruption of 5-HT1A function in adolescence but not early adulthood leads to sustained increases of anxiety
Keywords: 5-HIAA; 5-hydroxyindoleacetic; ANOVA; analysis of variance; DOX; doxycycline; EPM; elevated plus maze test; FST; forced swim test; SERT; 5-HT transporter; 5-HT1A; serotonin; anxiety; depression; adolescence; development;
Research PaperInfluence of urothelial or suburothelial cholinergic receptors on bladder reflexes in chronic spinal cord injured cats
Keywords: AMN; Atropine methyl nitrate; ATP; Adenosine triphosphate; 5-HT1A; Serotonergic receptor1A; 8-OH-DPAT; (±) 8-hydroxy-2-di-N-propylaminotetralin hydrobromide; BC; Bladder capacity; CMGs; Cystometrograms; MMP; Maximal micturition pressure; OXO-M; Oxotremor
The fatty acid amide hydrolase inhibitor URB597 modulates serotonin-dependent emotional behaviour, and serotonin1A and serotonin2A/C activity in the hippocampus
Keywords: 5-HT2A/C; 5-HT1A; Endocannabinoids; Electrophysiology; Fatty acid amide hydrolase;
Antidepressant-like activity of aroxyalkyl derivatives of 2-methoxyphenylpiperazine and evidence for the involvement of serotonin receptor subtypes in their mechanism of action
Keywords: Depression; Serotonin; 5-HT1A; 5-HT2A; 5-HT3; 5-HT7; 2-methoxyphenylpiperazine; Forced swim test
Synthesis, in vitro and in vivo pharmacological evaluation of serotoninergic ligands containing an isonicotinic nucleus
Keywords: Isonicotinamide derivatives; 5-HT1A; 5-HT2A and 5-HT2C ligands; Binding assays; In vitro assay; Behavioural tests;
Enhanced discriminative stimulus effects of Î9-THC in the presence of cannabidiol and 8-OH-DPAT in rhesus monkeys
Keywords: Cannabinoid; Rhesus monkey; Drug discrimination; Cannabidiol; 8-OH-DPAT; Serotonin; 5-HT1A; Rimonabant; Dependence;
The 5-HT1A receptor in Major Depressive Disorder
Keywords: 5-HT1A; Depression; Review;
Synthesis and binding properties of new long-chain 4-substituted piperazine derivatives as 5-HT1A and 5-HT7 receptor ligands
Keywords: Serotonin; 5-HT1A; 5-HT7; Ligands; Binding properties
Zinc, future mono/adjunctive therapy for depression: Mechanisms of antidepressant action
Keywords: Zinc; NMDA; 5-HT1A; GPR39; Depression
Neuroticism and serotonin 5-HT1A receptors in healthy subjects
Keywords: PET; [carbonyl-11C]WAY-100635; 5-HT1a; Neuroticism
Tryptophan hydroxylase and serotonin receptor 1A expression in the retina of the sea lamprey
Keywords: Agnathans; Retinal development; Sea lamprey; Amacrine cells; Neuroblasts; Serotonin 1A receptor; Tryptophan hydroxylase; 5-ht1a; serotonin 1A receptor mRNA; 5-HT1A; serotonin 1A receptor protein; HCL; horizontal cell sublayer; INbL; inner neuroblastic lay
Polymorphic variants of the serotonin receptor, 5-HT1A, and the serotonin transporter, 5-HTTLPR, and adverse pregnancy outcomes: A pilot study
Keywords: 5-HT1A; 5-HTTLPR; Antenatal depression; Early pregnancy loss; Serotonin
Research ReportDevelopment of theta rhythm in hippocampal formation slices perfused with 5-HT1A antagonist, (S)WAY 100135
Keywords: Theta; HPC; Slices; 5-HT1A; Serotonin; In vitro;
Effects of lighting condition on circadian behavior in 5-HT1A receptor knockout mice
Keywords: Mice; Serotonin; 5-HT1A; Dark pulse; Period; Amplitude; Circadian; Behavior;
Interactions of a standardized flavonoid fraction from Tilia americana with Serotoninergic drugs in elevated plus maze
Keywords: Tilia americana; Anxiety; Elevated plus-maze; 5-HT1A; 5-HT2-A; Flavonols;
Research reportContextual fear conditioning modulates hippocampal AMPA-, GluN1- and serotonin receptor 5-HT1A-containing receptor complexes
Keywords: cFC; contextual fear conditioning; BN-PAGE; blue-native PAGE; RC; receptor containing complexes; NMDAR; N-methyl-d-aspartate receptor; AMPAR; α-amino-3-hydroxyl-5-methyl-4-isoxazole propionate receptor; 5-HT1A; 5-hydroxytryptamine subtype 1A; Contextual
Research reportCombined serotonin (5-HT)1A agonism, 5-HT2A and dopamine D2 receptor antagonism reproduces atypical antipsychotic drug effects on phencyclidine-impaired novel object recognition in rats
Keywords: NOR; 5-HT1A; 5-HT2A; D2; Antipsychotic; Phencyclidine;
Serotonin receptor gene (5-HT1A) modulates alexithymic characteristics and attachment orientation
Keywords: Alexithymia; Attachment; Serotonin; Genetic polymorphism; 5-HT1A;
Genetic variation in brain-derived neurotrophic factor val66met allele is associated with altered serotonin-1A receptor binding in human brain
Keywords: BDNF; brain derived neurotrophic factor; 5-HT1A; serotonin 1A; HV; healthy volunteer; MDD; major depressive disorder; Met carriers; subjects with met/met or met/val genotype of val66met polymorphism; Met non-carriers; subjects with val/val genotype of val
The effects of chronic alcohol self-administration on serotonin-1A receptor binding in nonhuman primates
Keywords: Serotonin; 5-HT1A; PET imaging; Chronic alcohol self-administration; Rhesus monkey;
New 1-arylindoles based serotonin 5-HT7 antagonists. Synthesis and binding evaluation studies
Keywords: Serotonin; 5-HT7; 5-HT1A; Antagonist; Indole
Central amygdala nicotinic and 5-HT1A receptors mediate the reversal effect of nicotine and MDMA on morphine-induced amnesia
Keywords: 5-HT1A; 5-hydroxytryptamine 1A; ANOVA; analysis of variance; CeA; central amygdala; CPP; conditioned place preference; MDMA; 3,4-methylenedioxy-N-methylamphetamine; MORs; μ-opioid receptors; nACh; nicotinic acetylcholine; nAChRs; nicotinic acetylcholine
Structure–activity relationships and molecular modeling studies of novel arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones as 5-HT7 and 5-HT1A receptor ligands
Keywords: Serotonin; 5-HT7; 5-HT1A; Receptors; Ligands; LCAP
Looking for prosocial genes: ITRAQ analysis of proteins involved in MDMA-induced sociability in mice
Keywords: 5-HT1A; serotonin receptor subtype 1a; 5-HT2C; serotonin receptor subtype 2c; FDR; false discovery rate; GHB; gamma-hydroxybutyrate; GPCR; G-protein coupled receptor; iTRAQ; isobaric tag for relative and absolute quantification; LC; liquid chromatography;
Postnatal Fluoxetine-Evoked Anxiety Is Prevented by Concomitant 5-HT2A/C Receptor Blockade and Mimicked by Postnatal 5-HT2A/C Receptor Stimulation
Keywords: Antidepressant; DOI; 5-HT1A; 5-HT2A; 5-HT2C; ketanserin; Prozac; SSRI; WAY-100635
N-(4-[18F]-fluoropyridin-2-yl)-N-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}carboxamides as analogs of WAY100635. New PET tracers of serotonin 5-HT1A receptors
Keywords: 5-HT1A; Positron emission tomography; Fluorine-18; Radioligand; N-(4-[18F]-fluoropyridin-2-yl)-N-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}carboxamidesPET, positron emission tomography; 5-HT1A, receptor 1A of 5-hydroxytryptamine; 5-HT, 5-hydroxytryptami