Unaltered susceptibility to scrapie in serotonin transporter deficient mice
Keywords: Scrapie; Prion; 5-Hydroxytryptamine; Transporter
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Inhibition of the serotonin-induced inward current by dextromethorphan in rat nodose ganglion neurons
Keywords: 5-HT; 5-hydroxytryptamine; BD-1047; N-[2-(3,4-Dichlorophenyl)ethyl]-N-methyl-2-(dimethylamino)ethylamine; mCPBG; 1-(m-chlorophenyl)-biguanide hydrochloride; NMDA; N-methyl-d-aspartic acid; 5-HT3 receptor; Dextromethorphan; Patch-clamp recording; Vagal aff
Effects of (Z)-3-hexenol, a major component of green odor, on anxiety-related behavior of the mouse in an elevated plus-maze test and biogenic amines and their metabolites in the brain
Keywords: Green odor; Anxiety; (Z)-3-Hexenol; 5-Hydroxytryptamine; Dopamine; Elevated plus-maze
Detection of macronutrients in the intestinal wall
Keywords: Cholecystokinin; Vagal afferents; 5-Hydroxytryptamine; Free fatty acids; Glucose; Oligopeptides; PepT1; SGLT;
5-Hydroxytryptamine enhances larval development of the giant freshwater prawn, Macrobrachium rosenbergii
Keywords: 5-Hydroxytryptamine; Larvae; Growth; Prawn; Macrobrachium rosenbergii
Stabilization of the voltammetric serotonin signal by surfactants
Keywords: Electrode fouling; Voltammetry; Surfactants; 5-Hydroxytryptamine; Cetyl trimethyl ammonium chloride
Peripheral 5-HT2A receptor antagonism attenuates primary thermal hyperalgesia and secondary mechanical allodynia after thermal injury in rats
Keywords: 5-Hydroxytryptamine; 5-HT2A receptor antagonist; Sarpogrelate; Hyperalgesia; Microdialysis
Immunohistochemical localization of serotonin (5-hydroxytryptamine) in the gonad and digestive gland of Mya arenaria (Mollusca: Bivalvia)
Keywords: Serotonin; 5-Hydroxytryptamine; Marine bivalves; Mya arenaria; Gametogenesis; Gonad; Digestive gland; Immunohistochemistry; Prosorhynchus squamatus
A novel mechanism involved in 5-hydroxytryptamine-induced nociception: The indirect activation of primary afferents
Keywords: serotonin; pain; prostaglandin; dopamine; norepinephrine; adrenoceptors; AUC; area under the curve; MPO; myeloperoxidase; 5-HT; 5-hydroxytryptamine;
Serotonin transporter promoter variants: Analysis in Indian autistic and control population
Keywords: DSM-IV; Diagnostic and Statistical Manual of Mental Disorders-4th edition; HHRR; Haplotype-based haplotype relative risk; HWE; Hardy-Weinberg equilibrium; 5-HT; 5-hydroxytryptamine; 5-HTT; 5-hydroxytryptamine transporter; 5-HTTLPR; 5-HTT linked polymorp
Abnormalities of Serotonin Metabolism and Their Relation to Symptoms in Untreated Celiac Disease
Keywords: EC; enterochromaffin; 5-HIAA; 5-hydroxyindoleacetic acid; 5-HT; 5-hydroxytryptamine; HPLC; high-pressure liquid chromatography; IBS; irritable bowel syndrome.;
Neurotoxic effect of maneb in rats as studied by neurochemical and immunohistochemical parameters
Keywords: 5-Hydroxytryptamine; Fungicide; Manganese; Neurotoxicity; Parkinson's disease
A study of the role of serotonin in the anxiolytic effect of nitrous oxide in rodents
Keywords: Nitrous oxide; Anxiety; 5-Hydroxytryptamine; HPLC quantification of brain monoamines; Light/dark exploration test; Rats; Mice;
Locally administered antiproliferative drugs inhibit hypercontractility to serotonin in balloon-injured pig coronary artery
Keywords: FT; farnesyl transferase; 5-HT; 5-hydroxytryptamine; FPT III; farnesyl protein transferase inhibitor III; i.m.; intramuscular; LAD; left anterior descending coronary artery; LCx; left circumflex coronary artery; mTOR; mammalian target of rapamycin; Vascul
The nitric oxide synthesis/pathway mediates the inhibitory serotoninergic responses of the pressor effect elicited by sympathetic stimulation in diabetic pithed rats
Keywords: 5-hydroxytryptamine; Nitric oxide; Experimental diabetes; 5-HT1A receptors; Prejunctional inhibition
Behavioral, central monoaminergic and hypothalamo–pituitary–adrenal axis correlates of fear-conditioned analgesia in rats
Keywords: pain; corticosterone; 5-hydroxytryptamine; dopamine; periaqueductal gray; thalamusANOVA, analysis of variance; CPS, composite pain score; DOPAC, 3,4-dihydroxyphenylacetic acid; EDTA, ethylenediaminetetraacetic acid; FS-Form, footshock+formalin; FS-No Inj,
Safety and Tolerability of Tegaserod in Patients With Chronic Constipation: Pooled Data From Two Phase III Studies
Keywords: AEs; adverse events; CC; chronic constipation; CK; creatine kinase; CSBM; complete spontaneous bowel movement; ECG; electrocardiogram; GI; gastrointestinal; 5-HT; 5-hydroxytryptamine; IBS-C; irritable bowel syndrome with constipation; MedDRA; Medical Dict
Involvement of protein kinase C in 5-HT-evoked thermal hyperalgesia and spinal fos protein expression in the rat
Keywords: 5-HT; 5-hydroxytryptamine; 8-OH-DPAT; (±)-8-hydroxy-2-(di-n-propylamino)tetralin; α-m-5-HT; α-methylserotonin; c-fos-LI; c-Fos-like immunoreactivity; DMSO; dimethylsulphoxide; i.pl.; intraplantar or intraplantarly; PBS; phosphate-buffered saline; PKC;
Effect of morphine on locomotor activity and striatal monoamine metabolism in nicotine-withdrawn mice
Keywords: Nicotine; Withdrawal; Morphine; Locomotor activity; Dopamine; 5-Hydroxytryptamine; Noradrenaline
Multiple receptors mediate the trophic effects of serotonin on ventroposterior thalamic neurons in vitro
Keywords: 5-hydroxytryptamine; 5-HT receptor; Barrel; Neurite outgrowth; Serotonin; Somatosensory system; Thalamus; Tissue culture
Serotonin modulation of caudal photoreceptor in crayfish
Keywords: Cherax quadricarinatus; Procambarus clarkii; Neurotransmitter; Neuromodulator; Methysergide; 5-Hydroxytryptamine; 5-Hydroxytryptophan; l-Tryptophan; Tryptophan hydroxylase; Aromatic l-amino acid decarboxylase
Optimization of a pharmacophore model for 5-HT4 agonists using CoMFA and receptor based alignment
Keywords: 5-HT4; Agonist; Receptor; CoMFA; 5-Hydroxytryptamine;
Injections of urocortin 1 into the basolateral amygdala induce anxiety-like behavior and c-Fos expression in brainstem serotonergic neurons
Keywords: anxiety; fear; corticotropin-releasing factor; serotonin; 5-hydroxytryptamine; basolateral amygdaloid nucleusANOVA, analysis of variance; BLA, basolateral amygdaloid nucleus, anterior part; BLP, basolateral amygdaloid nucleus, posterior part; BLV, basolat
Acute intranigral homocysteine administration produces stereotypic behavioral changes and striatal dopamine depletion in Sprague-Dawley rats
Keywords: AD; Alzheimer's disease; COMT; catechol-O-methyl transferase; DA; dopamine; DOPAC; 3,4-dihydroxyphenylacetic acid; 5-HIAA; 5-hydroxyindolecaetic acid; 5-HT; 5-hydroxytryptamine; HVA; homovanillic acid; l-DOPA; levodopa; MPP+; 1-methyl-4-phenylpyridinium;
Evidence supporting a role for corticotropin-releasing factor type 2 (CRF2) receptors in the regulation of subpopulations of serotonergic neurons
Keywords: Neurotransmitters, modulators, transporters, and receptors, SerotoninSerotonin; 5-hydroxytryptamine; Antisauvagine-30; Urocortin 2; Raphe; Anxiety
Treatment of nausea and vomiting: Gaps in our knowledge
Keywords: Nausea; Vomiting; Gastroesophageal reflux disease; Dyspepsia; Ferret; Dopamine; 5-Hydroxytryptamine; Gamma amino butyric acid; Substance P; Cannabinoid receptors; Opioid receptors; Ghrelin; Muscarinic receptor antagonists
5-Hydroxytryptamine synthesis in HL-1 cells and neonatal rat cardiocytes
Keywords: 5-Hydroxytryptamine; HL-1 cardiomyocytes; Neonatal rat cardiac myocytes; Neonatal rat cardiac non-myocytes; HLPC;
Effects of CGS-12066A on medial vestibular nuclear neurons
Keywords: Motor systems and sensorimotor integration; Vestibular system; 5-hydroxytryptamine; Medial vestibular nucleus; Action potential; Potassium current;
Management of Delayed Gastric Emptying
Keywords: FDA; Food and Drug Administration; 5-HT; 5-hydroxytryptamine;
A novel mutagen, 2-(5-hydroxy-4,6-dinitroindolyl) ethanol, formed in the reaction between 5-hydroxytryptamine and nitrite under acid conditions, especially in the presence of l-cysteine
Keywords: 5-Hydroxytryptamine; Mutagenic activity; Nitrite; l-Cysteine; Ames test;
Effects of injections of 8-hydroxy-2-(di-n-propylamino)tetralin or muscimol in the median raphe nucleus on c-fos mRNA in the rat brain
Keywords: 5-hydroxytryptamine; GABA; in situ hybridization; locomotor activity; reinstatement; relapse; BLA; basolateral amygdala; BST; bed nucleus of the stria terminalis; LC; locus coeruleus; LS; lateral septum; MFC; medial frontal cortex; MRN; median raphe nucle
Maternal ethanol administration inhibits 5-hydroxytryptamine synthesis and tryptophan hydroxylase expression in the dorsal raphe of rat offspring
Keywords: Maternal ethanol intake; 5-Hydroxytryptamine; Tryptophan hydroxylase; Dorsal raphe;
Effects of substance P and its antagonist L-733060 on long term potentiation in guinea pig hippocampal slices
Keywords: 5-HT; 5-hydroxytryptamine; fEPSP; field excitatory postsynaptic potential; HFS; high frequency stimulation; LTP; long term potentiation; NK-1; neurokinin-1; NMDA; N-methyl-d-aspartate; SP; substance P; CA 1; Field potentials; Guinea pig; Hippocampus; Long
5-Hydroxytryptamine as a potent migration enhancer of human aortic endothelial cells
Keywords: ERK; 5-Hydroxytryptamine; Migration; Rho kinase; Vascular endothelium
Human brain imaging and substance abuse
Keywords: 5HT; 5-hydroxytryptamine; 5HTT; 5HT transporter; fMRI; functional magnetic resonance imaging; PET; positron emission tomography; rCBF; regional cerebral blood flow; SPET; single photon emission tomography;
5-Hydroxytryptamine augments migration of human aortic smooth muscle cells through activation of RhoA and ERK
Keywords: Atherosclerosis; Cytoskeleton; 5-Hydroxytryptamine; MAP kinase; Serotonin; Signal transduction;
Chronic treatment with mianserin prevents DOCA-salt hypertension in rats-evidence for the involvement of central 5-HT2 receptors
Keywords: 5-hydroxytryptamine; Deoxycorticosterone acetate; Experimental hypertension; 5-HT2 receptor; Mianserin;
Serotonin glucuronidation by Ah receptor- and oxidative stress-inducible human UDP-glucuronosyltransferase (UGT) 1A6 in Caco-2 cells
Keywords: UGT; UDP-glucuronosyltransferase; 5-HT; 5-hydroxytryptamine; 5-HT-GA; 5-hydroxytryptamine glucuronide; MUF; 4-methylumbelliferone; TCDD; 2,3,7,8-tetrachlorodibenzo-p-dioxin; BNF; β-naphthoflavone; tBHQ; tert-butylhydroquinone; TQ; thymoquinone; NQO1; NAD
δ-opioid receptor-mediated actions on rostral ventromedial medulla neurons
Keywords: ACSF; artificial cerebrospinal fluid; BSA; bovine serum albumin; DAMGO; [d-Ala2, NMe-Phe4, Gly-ol5]-enkephalin; deltorphin-II; [d-Ala2]-deltorphin II; DPDPE; [d-Pen2; d-Pen5]-enkephalin; RVM; rostral ventromedial medulla; TPH; tryptophan hydroxylase; TPH-
FlexStation examination of 5-HT3 receptor function using Ca2+- and membrane potential-sensitive dyes: Advantages and potential problems
Keywords: 5-HT; 5-hydroxytryptamine; nACh receptor; nicotinic acetylcholine receptor; HEK; human embryonic kidney; WT; wild type; Serotonin receptor; Fluorescent dye; 5-HT3 receptor; Membrane potential dye; Calcium sensitive dye; Dye saturation;
Regulation of the amyloid precursor protein ectodomain shedding by the 5-HT4 receptor and Epac
Keywords: ACh; acetylcholine; AD; Alzheimer's disease; ADAM; a disintegrin and metalloprotease; Aβ; amyloid β-peptide; APP; amyloid precursor protein; sAPPα; soluble form of the amyloid precursor protein; FSK; forskolin; GEF; guanine nucleotide exchange factor
Sleep Disturbance and Rage Attacks in Opsoclonus-Myoclonus Syndrome: Response to Trazodone
Keywords: ACTH; Adrenocorticotropic hormone (corticotropin); ADD; Attention deficit disorder; ADHD; Attention deficit hyperactivity disorder; CSF; Cerebrospinal fluid; 5-HIAA; 5-hydroxyindoleacetic acid; 5-HT; 5-hydroxytryptamine; HVA; Homovanillic acid; m-CPP; m-c
GABAergic modulation mediates antinociception produced by serotonin applied into thalamic nucleus submedius of the rat
Keywords: Sensory systems; Pain modulation: pharmacology; GABAergic modulation; Bicuculline; 5-hydroxytryptamine; Thalamic nucleus submedius; Antinociception; Tail flick;
An acute hyperglycemia or acidosis-induced changes of indolamines level correlates with PKC-α expression in rat brain
Keywords: CB; cerebellum; CCX; cerebral cortex; 5-HT; 5-hydroxytryptamine; 5-HIAA; 5-hydroxyindoleacetic acid; HC; hippocampus; HT; hypothalamus; MB; midbrain; NaAcAc; sodium acetoacetate; NH4Cl; ammonium chloride; PM; pons medulla; ST; striatum; Hyperglycemia; Aci
Influence of forced swimming stress on 5-HT1A receptors and serotonin levels in mouse brain
Keywords: CRH; corticotrophin-releasing hormone; DRN; dorsal raphe nuclei; FS; forced swimming; GABA; gamma-aminobutyric acid; HPLC; high performance liquid chromatography; 5HIAA; 5-hydroxyindolacetic acid; 5-HT; 5-hydroxytryptamine; MRN; median raphe nuclei; OD; o
Distinct effects of sleep deprivation on binding to norepinephrine and serotonin transporters in rat brain
Keywords: AON; Anterior olfactory nucleus; DASB; 3-Amino-4-(2-dimethylaminomethyl-phenylsulfanyl)-benzonitrile; 5-HT; 5-hydroxytryptamine; NE; norepinephrine; NET; norepinephrine transporter; REM; rapid eye movement; SD; sleep deprivation; SERT; serotonin transport
Potentiation of platelet aggregation by heparin in human whole blood is attenuated by P2Y12 and P2Y1 antagonists but not aspirin
Keywords: UFH; unfractionated heparin; A2P5P; adenosine-2,5-bisphosphate; TRAP; thrombin receptor activating peptide; PAF; platelet-activating factor; 5HT; 5-hydroxytryptamine; Platelets; Platelet aggregation inhibitors; P2 receptor; Heparin; Cangrelor;
Ecstasy: pharmacology and neurotoxicity
Keywords: 5-HT; 5-hydroxytryptamine; DA; dopamine; MDMA; 3,4-methylene-dioxymethamphetamine; NE; norepinephrine; PD; Parkinson's disease;
The tryptophan hydroxylase activation inhibitor, AGN-2979, decreases regional 5-HT synthesis in the rat brain measured with α-[14C]methyl-l-tryptophan: An autoradiographic study
Keywords: α-MTrp; α-[14C]methyl-l-tryptophan; DRN; dorsal raphe nucleus; MRN; median raphe nucleus; TPH; tryptophan hydroxylase; 5-HT; 5-hydroxytryptamine; 5-HIAA; 5-hydroxyindoleacetic acid; α-Methyl-l-tryptophan; Autoradiography; Serotonin synthesis rate; AGN-
Effect of 5-hydroxytryptamine on vagal C-fiber subtypes in guinea pig lungs
Keywords: C-fiber; Nodose ganglion; 5-Hydroxytryptamine; Ondansetron; Afferent; Lung; Vagus nerve; Guinea pig;