Keywords: 8-OHdG، 8-هیدروکسی دیواکسی گوازوزین; MT, melatonin; SOD, superoxide dismutase; Gpx, glutathione peroxidase; 8-OHdG, 8-hydroxydeoxyguanosine; ROS, reactive oxygen species; RNS, reactive nitrogen species; UA, umbilical artery; UV, umbilical vein; BGA, blood gas analyses; ELISA, enzyme linked i
مقالات ISI 8-OHdG، 8-هیدروکسی دیواکسی گوازوزین (ترجمه نشده)
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Keywords: 8-OHdG، 8-هیدروکسی دیواکسی گوازوزین; 8-OHdG, 8-hydroxydeoxyguanosine; ANCOVA, analysis of covariance; BMI, body mass index; ELISA, enzyme-linked immunosorbent assay; CLEB, cranberry leaf extract beverage; CRP, C-reactive protein; GPx, glutathione peroxidase; GSH, reduced glutathione; GSSG, o
Lyophilized strawberries prevent 7,12-dimethylbenz[α]anthracene (DMBA)-induced oral squamous cell carcinogenesis in hamsters
Keywords: 8-OHdG، 8-هیدروکسی دیواکسی گوازوزین; Oral squamous cell carcinoma; Chemoprevention; Strawberry; Hamster; DMBADMBA, 7,12-dimethylbenz[α]anthracene; SCC, squamous cell carcinoma; BrdU, bromodeoxyuridine; 8-OHdG, 8-hydroxydeoxyguanosine; H2O2, hydrogen peroxide; MVD, microvessel density; ERK, e
MicroRNA expression profiling and functional annotation analysis of their targets in patients with type 1 diabetes mellitus
Keywords: 8-OHdG، 8-هیدروکسی دیواکسی گوازوزین; 8-OHdG, 8-hydroxydeoxyguanosine; AGO1, argonaute-1; ALS, amyotrophic lateral sclerosis; AUC, area under the curve; CCL2, C–C motif chemokine 2; CCL3, C–C motif chemokine 3; CCL4, C–C motif chemokine 4; CDS, coding sequence; CTLA4, cytotoxic T-lymphocyte-a
A perspective on the role of estrogen in hormone-induced prostate carcinogenesis
Keywords: 8-OHdG، 8-هیدروکسی دیواکسی گوازوزین; 4OH-E2, 4-hydroxyestradiol; 8-OHdG, 8-hydroxydeoxyguanosine; AR, androgen receptors; DHT, 5α-dihydrotestosterone; E2, 17β-estradiol; ER, estrogen receptor; LH, luteinizing hormone; PSA, prostate specific antigen; ROS, reactive oxygen species; SNP, single
Increased vulnerability of hippocampal CA1 neurons to hypoperfusion in ataxia and male sterility (AMS) mouse
Keywords: 8-OHdG، 8-هیدروکسی دیواکسی گوازوزین; AMS, ataxia and male sterility; pcd, Purkinje cell degeneration; WT, wild type; BCCAO, bilateral common carotid artery occlusion; GSH, glutathione; 8-OHdG, 8-hydroxydeoxyguanosine; UCP2, mitochondrial uncoupling protein 2; PComA, posterior communicating a
Stressed out mitochondria: The role of mitochondria in ageing and cancer focussing on strategies and opportunities in human skin
Keywords: 8-OHdG، 8-هیدروکسی دیواکسی گوازوزین; 8-OHdG, 8-hydroxydeoxyguanosine; ADP, adenosine diphosphate; ATP, adenosine triphosphate; bp, base pairs; CPD, cyclobutane pyrimidine dimer; D-loop, displacement loop; DNA, deoxyribonucleic acid; EPR, electroparamagnetic resonance; ERK1/2, extracellular s
Short-term calorie restriction protects against renal senescence of aged rats by increasing autophagic activity and reducing oxidative damage
Keywords: 8-OHdG، 8-هیدروکسی دیواکسی گوازوزین; CR, calorie restriction; SDRs, Sprague–Dawley rats; AL, ad libitum; Y, young; O, old; CKD, chronic kidney disease; PAS, periodic acid-Schiff; SA-β-gal, senescence-associated β-galactosidase; 8-OHdG, 8-hydroxydeoxyguanosine; mtDNA, mitochondrial DNA; AMPK,
Exercising the worry away: How inflammation, oxidative and nitrogen stress mediates the beneficial effect of physical activity on anxiety disorder symptoms and behaviours
Keywords: 8-OHdG، 8-هیدروکسی دیواکسی گوازوزین; 5-HT1aR, serotonin 1A receptor; 8-OHdG, 8-hydroxydeoxyguanosine; AIC, anti-inflammatory cytokine; BDNF, brain derived neurotrophic factor; cAMP, cyclic adenosine monophosphate; CAT, catalase; CMI, cell-mediated immune; COX2, cyclo-oxygenase 2; CREB, cAMP
Kwashiorkor and marasmus are both associated with impaired glucose clearance related to pancreatic β-cell dysfunction
Keywords: 8-OHdG، 8-هیدروکسی دیواکسی گوازوزین; FFA, free fatty acids; OGTT, oral glucose tolerance test; MUAC, mid upper arm circumference; 8-OhdG, 8-hydroxydeoxyguanosine; MDA, malondialdehyde; TTR, tracer-to-tracee ratio; EGP, endogenous glucose production; SEM, standard error of the mean
Methylglyoxal promotes oxidative stress and endothelial dysfunction
Keywords: 8-OHdG، 8-هیدروکسی دیواکسی گوازوزین; 8-OHdG, 8-hydroxydeoxyguanosine; AGEs, advanced glycation end products; CEL, Nɛ-carboxyethyl-lysine; DAPI, 4′,6-diamidino-2-phenylindole; DHE, dihydroethidium; eNOS, endothelial nitric oxide synthase; FFA, free fatty acids; GK rats, Goto-Kakizaki rats; l-
The redox stress hypothesis of aging
Keywords: 8-OHdG، 8-هیدروکسی دیواکسی گوازوزین; ETC, electron transport chain; GCL, glutamate cysteine ligase; GSH, reduced glutathione; GSSG, oxidized glutathione; G6PD, glucose-6-phosphate dehydrogenase; HNE, 4-hydroxy-2-trans-nonenal; 8-OHdG, 8-hydroxydeoxyguanosine; MDA, malondialdehyde; MLS, maxim
Changes in pro/antioxidant balance in smoking and non-smoking pregnant women with intrauterine growth restriction
Keywords: 8-OHdG، 8-هیدروکسی دیواکسی گوازوزین; 8-OHdG, 8-hydroxydeoxyguanosine; Cd, cadmium; Cu, copper; Cu/Zn SOD, Cu/Zn superoxide dismutase; GPx, glutathione peroxidase; GSH, glutathione; IUGR, intrauterine growth restriction; MDA, malondialdehyde; MT, metallothionein; Pb, lead; Zn, zinc8-Hydroxyde
Folate deficiency regulates expression of DNA polymerase β in response to oxidative stress
Keywords: 8-OHdG، 8-هیدروکسی دیواکسی گوازوزین; β-pol, DNA polymerase β; BER, base excision repair; CRE, cAMP response element; CREB, cAMP response element binding protein; 8-OHdG, 8-hydroxydeoxyguanosine; 2dG, deoxyguanosineOxidative stress; DNA polymerase β; Base excision repair; cAMP response elemen
A novel approach for stress-induced gastritis based on paradoxical anti-oxidative and anti-inflammatory action of exogenous 8-hydroxydeoxyguanosine
Keywords: 8-OHdG، 8-هیدروکسی دیواکسی گوازوزین; ROS, reactive oxygen species; 8-OHdG, 8-hydroxydeoxyguanosine; WIRS, water immersion restraint stress; NOX, NADPH oxidase; Rac-GTP, a subfamily of the Rho family of GTPases; Rac-GEF, Rac-Guanosine exchange factor; NF-κB, nuclear factor-kappaB; HUVEC, huma
A radiation-induced adaptive response prolongs the survival of prion-infected mice
Keywords: 8-OHdG، 8-هیدروکسی دیواکسی گوازوزین; PrP, prion protein; ROS, reactive oxygen species; dpi, days postinfection; 8-OHdG, 8-hydroxydeoxyguanosine; HSF-1, heat shock factor 1Prion; Low-dose irradiation; Oxidative stress; Adaptive response; ME-7; Mice; Neurodegeneration; Free radicals
Imbalance of oxidative/anti-oxidative status induced by periodontitis is involved in apoptosis of rat submandibular glands
Keywords: 8-OHdG، 8-هیدروکسی دیواکسی گوازوزین; TNF-α, tumour necrosis factor-α; TUNEL, terminal deoxynucleotidyl transferase-mediated dUTP nick-end labelling; ROS, reactive oxygen species; 8-OHdG, 8-hydroxydeoxyguanosine; ROM, reactive oxygen metabolites; PAO, potential anti-oxidant; CARR U, Carratell
Effect of oxidative stress during repeated ovulation on the structure and functions of the ovary, oocytes, and their mitochondria
Keywords: 8-OHdG، 8-هیدروکسی دیواکسی گوازوزین; mtDNA, mitochondrial DNA; Tfam, mitochondrial transcription factor A; NRF1, nuclear respiratory factor 1; PMSG, pregnant mare serum gonadotropin; hCG, human chorionic gonadotropin; PGF2α, prostaglandin F2α; 8-OHdG, 8-hydroxydeoxyguanosine; SOD, superoxide
Ezetimibe decreases serum levels of asymmetric dimethylarginine (ADMA) and ameliorates renal injury in non-diabetic chronic kidney disease patients in a cholesterol-independent manner
Keywords: 8-OHdG، 8-هیدروکسی دیواکسی گوازوزین; NO, nitric oxide; CKD, chronic kidney disease; CVD, cardiovascular disease; ADMA, asymmetric dimethylarginine; DDAH, dimethylarginine dimethylaminohydrolase; BP, blood pressure; 8-OHdG, 8-hydroxydeoxyguanosine; l-FABP, l-fatty acid binding protein; T-Chol
The role of oxidative stress in deoxynivalenol-induced DNA damage in HepG2 cells
Keywords: 8-OHdG، 8-هیدروکسی دیواکسی گوازوزین; Deoxynivalenol; Comet assay; Lipid peroxidation; Oxidative stress; HepG2 cellsDON, deoxynivalenol; HT, hydroxytyrosol; ROS, reactive oxygen species; DCFH-DA, 2,7-dichlorofluorescein diacetate; 8-OHdG, 8-hydroxydeoxyguanosine; TBARS, thiobarbituric acid-re
Effects of vitamin C intake on gingival oxidative stress in rat periodontitis
Keywords: 8-OHdG، 8-هیدروکسی دیواکسی گوازوزین; 8-OHdG, 8-hydroxydeoxyguanosine; DnaJ, DnaJ (Hsp40) homolog, subfamily A, member 1; GSH, reduced form of glutathione; GSSG, oxidized form of glutathione; Hspa1a, heat shock 70-kDa protein 1a; IL-1α, interleukin-1α; IL-1β, interleukin-1β; IL-6, interleukin
Dietary n-3 polyunsaturated fatty acids increase oxidative stress in rats with intracerebral hemorrhagic stroke
Keywords: 8-OHdG، 8-هیدروکسی دیواکسی گوازوزین; 8-OHdG, 8-hydroxydeoxyguanosine; DHA, docosahexaenoic acid; EPA, eicosapentaenoic acid; GSH, glutathione; ICH, intracerebral hemorrhagic; MRI, magnetic resonance imaging; PUFA, polyunsaturated fatty acid; SOD, superoxide dismutase; TBAR, thiobarbituric ac
Enhancement of preneoplastic lesion yield by Chios Mastic Gum in a rat liver medium-term carcinogenesis bioassay
Keywords: 8-OHdG، 8-هیدروکسی دیواکسی گوازوزین; BrdU, 5-bromo-2′-deoxyuridine; CMG, Chios Mastic Gum; CYP, cytochrome P450; DEN, diethylnitrosamine; GST-P, glutathione S-transferase placental form; 8-OHdG, 8-hydroxydeoxyguanosine; PCR, polymerase chain reaction.Chios Mastic Gum; GST-P foci; Ito-test; R
Vitamin C intake attenuates the degree of experimental atherosclerosis induced by periodontitis in the rat by decreasing oxidative stress
Keywords: 8-OHdG، 8-هیدروکسی دیواکسی گوازوزین; HEL, hexanoyl-lysine; 8-OHdG, 8-hydroxydeoxyguanosine; GSH, reduced form glutathione; GSSG, oxidized form glutathione; TNF-α, tumour necrosis factor-α; HE, haematoxylin and eosinVitamin C; Atherosclerosis; Periodontal disease; Oxidative stress
The evaluation of oxidative DNA damage in children with brain damage using 8-hydroxydeoxyguanosine levels
Keywords: 8-OHdG، 8-هیدروکسی دیواکسی گوازوزین; 8-OHdG, 8-hydroxydeoxyguanosine; CSF, cerebrospinal fluid; SE, status epilepticus; HIE, hypoxic–ischemic encephalophathy; CNS, central nervous system; HHV-6, human herpes virus 6; ROS, reactive oxygen speciesBrain damage; 8-OHdG; Oxidative stress; Free ra
Hydroquinone-induced genotoxicity and oxidative DNA damage in HepG2 cells
Keywords: 8-OHdG، 8-هیدروکسی دیواکسی گوازوزین; DCFH-DA, 2,7-dichlorofluorescein diacetate; DPC, DNA–protein crosslinks; 8-OHdG, 8-hydroxydeoxyguanosine; GSH, glutathione; MNT, micronucleus test; OPT, o-phthalaldehyde; ROS, reactive oxygen species; SCGE, single cell gel electrophoresisHydroquinone; Sin
PON1Q192R genetic polymorphism modifies organophosphorous pesticide effects on semen quality and DNA integrity in agricultural workers from southern Mexico
Keywords: 8-OHdG، 8-هیدروکسی دیواکسی گوازوزین; PON1, human paraoxonase 1; OP, organophosphorous pesticides; 8-OHdG, 8-hydroxydeoxyguanosine; NT, nick translation; BMI, body mass index.PON1 polymorphisms; Organophosphorous pesticides; Sperm DNA damage; Semen quality
Infrared spectroscopy: a reagent-free method to distinguish Alzheimer's disease patients from normal-aging subjects
Keywords: 8-OHdG، 8-هیدروکسی دیواکسی گوازوزین; 8-epi-PGF2α, 8-epi-prostaglandin F2α; 8-OHdG, 8-hydroxydeoxyguanosine; AD, Alzheimer's disease; CSF, cerebrospinal fluid; ELISA, enzyme-linked immunosorbent assay; FT-IR, Fourier-transform infrared; HPLC, high-performance liquid chromatography; HRP, horse
Genotoxic effect and nitrative DNA damage in HepG2 cells exposed to aristolochic acid
Keywords: 8-OHdG، 8-هیدروکسی دیواکسی گوازوزین; AA, aristolochic acid; MN, micronucleus; RNS, reactive nitrogen species; NO, nitric oxide; 8-OHdG, 8-hydroxydeoxyguanosine; DAN, 2,3-diaminonaphthalene; EtBr, ethidium bromide; BNC, binucleated cellsAristolochic acid; Genotoxicity; Nitric oxide; HepG2 cel
Modulation of aflatoxin toxicity and biomarkers by lycopene in F344 rats
Keywords: 8-OHdG، 8-هیدروکسی دیواکسی گوازوزین; AFB1, aflatoxin B1; AFM1, aflatoxin M1; AFQ1, aflatoxin Q1; AFP1, aflatoxin P1; AFB–NAC, AFB1–mecapturic acid; AFB–N7-Gua, Aflatoxin B1–N7-guanine; b.w., body weight; 8-OHdG, 8-hydroxydeoxyguanosine; RIA, radioimmunoassay; TEAF, triethylammonium formateLy
Hypoadiponectinemia accelerates hepatic tumor formation in a nonalcoholic steatohepatitis mouse model
Keywords: 8-OHdG، 8-هیدروکسی دیواکسی گوازوزین; 8-OHdG, 8-hydroxydeoxyguanosine; ACC, acetyl-CoA carboxylase; AdAN, adenovirus that produces full-length mouse adiponectin; AdLacZ, adenovirus that produces β-galactosidase; α-SMA, α-smooth muscle actin; ALT, alanine transaminase; AMPK, AMP-activated prot
Polymorphism of selected enzymes involved in detoxification and biotransformation in relation to lung cancer
Keywords: 8-OHdG، 8-هیدروکسی دیواکسی گوازوزین; 8-OHdG, 8-hydroxydeoxyguanosine; 95% CI, 95% confidence interval; AC, adenocarcinoma; AH, aryl hydrocarbon; CYP, cytochrome P450; EPHX1, microsomal epoxide hydrolase; GPx, glutathione peroxidase; GSTs, glutathione S-transferases; LOH, loss of heterozygosi
Oxidative damage of periodontal tissue in the rat periodontitis model: Effects of a high-cholesterol diet
Keywords: 8-OHdG، 8-هیدروکسی دیواکسی گوازوزین; 8-OHdG, 8-hydroxydeoxyguanosine; IL-1β, interleukin 1 beta; TNF-α, tumor necrosis factor alpha; LPS, lipopolysaccharideDietary cholesterol; Periodontitis; Tissue oxidative damage
Linking inflammation and atherogenesis: Soluble markers identified for the detection of risk factors and for early risk assessment
Keywords: 8-OHdG، 8-هیدروکسی دیواکسی گوازوزین; AGE, advanced glycation end products; CAD, coronary artery disease; CD40L, CD 40 ligand; COX 2, cyclooxygenase 2; CRP, C-reactive protein; HDL, high density lipoprotein; HbA1c, hemoglobin A1c; 8-OHdG, 8-hydroxydeoxyguanosine; ICAM, intracellular adhesion
NADPH oxidase is involved in angiotensin II-induced apoptosis in H9C2 cardiac muscle cells: Effects of apocynin
Keywords: 8-OHdG، 8-هیدروکسی دیواکسی گوازوزین; Ang II, angiotensin II; ROS, reactive oxygen species; SOD, superoxide dismutase; RT-PCR, reverse transcription polymerase chain reaction; carboxy-H2DCFDA, 5-(and-6)-carboxy-2′7′-dichlorodihydrofluorescein diacetate; 8-OHdG, 8-hydroxydeoxyguanosine; TUNEL,
Absence of toxic effects in F344/N rats and B6C3F1 mice following subchronic administration of chromium picolinate monohydrate
Keywords: 8-OHdG، 8-هیدروکسی دیواکسی گوازوزین; CPM, chromium picolinate monohydrate; NTP, National Toxicology Program; 8-OHdG, 8-hydroxydeoxyguanosine; Chromium; Feed; Mice; NTP; Picolinate; Rats; Subchronic; Supplement; Toxicity;