Keywords: Health claims; Claimed effect; Outcome variable; Method of measurement; Oxidative damage; Cardiovascular health; 8-OHdG; 8-hydroxy-2-deoxy-guanosine; 8-oxo-dG; 8-oxo-2-deoxyguanosine; ABPM; Ambulatory blood pressure monitoring; ADP; Adenosine diphosphate;
مقالات ISI (ترجمه نشده)
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Keywords: 2,4-D; dichlorophenoxyacetic acid; [35S]TBPS; [35S]tertiary-butylbicyclophosphorothionate; 3-NP; 3-nitropropionic acid; 4CL; 4-coumarate: CoA ligase; 4-O-MH; 4-O-methylhonokiol; 6-OHDA; 6-hydroxydopamine; 8-oxo-dG; 8-oxo-2â²-deoxyguanosine; AChE; acetylc
Keywords: Single-walled carbon nanotubes; Carbon nanotubes; Nanomaterials; Nanotoxicology; Pulmonary toxicology; Inflammation; Oxidative stress; Inhalation; Pharyngeal aspiration; Intratracheal instillation; ACE; angiotensin-converting enzyme; AD-SWCNTs; acetone/so
Keywords: TM; trabecular meshwork; HTM; human trabecular meshwork; BKA; Benzalkonium chloride; PLYQ; polyquad; SFZ; sofzia like mixture; PRT; purite; 8-oxo-dG; 8-hydroxy-2â²-deoxyguanosine; Drug preservatives; Glaucoma; Trabecular meshwork; Oxidative damage; Micro
Keywords: 8-Oxo-dG; Oxidative stress; Predictive assay; Radiosensitivity; Breast cancer; Radiotherapy;
Keywords: ACC; acetyl-CoA carboxylase; Ahcy; adenosylhomocysteinase; AT; adipose tissue; ATGL; adipose triglyceride lipase; AMPK; AMP-activated protein kinase; Bhmt; betaine-homocysteine S-methyltransferase; CR; caloric restriction; CBS; cystathionine β-synthase;
Keywords: AUC; area under the curve; BMI; body mass index; CHD; coronary heart disease; 8-oxo-dG; 8-oxo-7,8-dihydro-2'-deoxyguanosine; FH; familial hypercholesterolemia; GPX; glutathione peroxidase; GSH; reduced glutathione; GSSG; oxidized glutathione; HPLC; high
Impact of DNA polymerase ζ mutations on genotoxic thresholds of oxidative mutagens
Keywords: TLS; translesion DNA synthesis; Pol; DNA polymerase; KBrO3; potassium bromate; Na2Cr2O7; sodium dichromate; 8-oxo-dG; 7,8-dihydro-8-oxo-2â²-deoxyguanosine; D2781N; a human cell line that expresses a variant form of Pol ζ having asparagine instead of asp
Enhanced Repair of UV-Induced DNA Damage by 1,25-Dihydroxyvitamin D3 in Skin Is Linked to Pathways that Control Cellular Energy
Keywords: 1,25(OH)2D3; 1α,25-dihydroxyvitamin D3; 2-dG; 2-deoxy-d-glucose; 8-oxo-dG; 8-oxo-2â²-deoxyguanosine; Akt; acutely transforming retrovirus AKT8 in rodent T-cell lymphoma; CPD; cyclobutane pyrimidine dimer; ÎÏm; mitochondrial membrane potential; ECAR; e
Protective effect of the ethanol extract from Ligusticum chuanxiong rhizome against streptozotocin-induced diabetic nephropathy in mice
Keywords: AEL; aqueous extract of L. chuanxiong rhizome; ARE; antioxidant response element; COX-2; cyclooxygenase-2; DI; didox; DN; diabetic nephropathy; EEL; ethanol extract of L. chuanxiong rhizome; ELISA; enzyme linked immunosorbent assay; ESRD; end stage renal
The role of the iron catalyst in the toxicity of multi-walled carbon nanotubes (MWCNTs)
Keywords: CNT; carbon nanotubes; pMWCNT; pristine multi-walled carbon nanotubes; fMWCNT; acid-treated multi-walled carbon nanotubes; CCVD; catalytic chemical vapor deposition; FCS; fetal calf serum; PBS; phosphate buffered saline; FACS; Fluorescence-activated cell
Elevated urinary levels of 8-oxo-2â²-deoxyguanosine, (5â²R)- and (5â²S)-8,5â²-cyclo-2â²-deoxyadenosines, and 8-iso-prostaglandin F2α as potential biomarkers of oxidative stress in patients with prediabetes
Keywords: 8-oxo-dG; 8-oxo-2â²-deoxyguanosine; R-cdA and S-cdA; (5â²R)- and (5â²S)-8,5â²-cyclo-2â²-deoxyadenosines; 8-iso-PGF2α; 8-iso-prostaglandin F2α; T2DM; type 2 diabetes mellitus; LC-MS/MS; liquid chromatography-isotope dilution tandem mass spectrom
Metformin inhibits age-related centrosome amplification in Drosophila midgut stem cells through AKT/TOR pathway
Keywords: 4E-BP; eukaryotic translation initiation factor 4E-binding protein; 8-oxo-dG; 8-oxo-2â²-deoxyguanosine; AMPK; 5â² AMP-activated protein kinase; EBs; enteroblasts; ECs; enterocytes; EEs; enteroendocrine cells; EGFR; epidermal growth factor receptor; IGF1
The potential role of melatonin on sleep deprivation-induced cognitive impairments: Implication of FMRP on cognitive function
Keywords: 4-HNE; 4-hydroxynonenal; 8-oxo-dG; 7,8-dihydro-8-oxo-deoxyguanine; AD; Alzheimer's disease; ANOVA; analysis of variance; ASD; autism spectrum disorders; DCFH2-DA; 2â²,7â²-dichlorodihydrofluorescein diacetate; DMSO; dimethyl sulfoxide; FMRP; fragile X
Polycyclic aromatic hydrocarbons (PAH) and their genotoxicity in exhaust emissions from a diesel engine during extended low-load operation on diesel and biodiesel fuels
Keywords: Biodiesel; Diesel particulate matter; DNA adducts; Emissions; Idling; Creep; DNA oxidative damage; Polycyclic aromatic hydrocarbons; Toxicity of emissions; B[a]P; benzo[a]pyrene; cPAH; carcinogenic PAH: benzo[a]anthracene, chrysene, benzo[b]fluoranthene,
Antitumor effect of pharmacologic ascorbate in the B16 murine melanoma model
Keywords: ATCC; American type culture collection; BCA; bicinchoninic acid; Cdc42; cell division control protein 42; D-MEM; Dulbecco's modified Eagle's medium; DNA; deoxyribonucleic acid; DTPA; diethylenetriaminepentaacetic acid; ECL; enhanced chemiluminescence;
Compensatory effects of hOGG1 for hMTH1 in oxidative DNA damage caused by hydrogen peroxide
Keywords: RNAi; hOGG1; hMTH1; 8-oxo-dG; Compensatory effects
CYP2E1 induction leads to oxidative stress and cytotoxicity in glutathione-depleted cerebellar granule neurons
Keywords: CGNs; cerebellar granule neurons; CYP2E1; cytochrome P450 2E1; ROS; reactive oxygen species; GSH; glutathione; DIV; days in vitro; INH; isoniazid; BSO; l-buthionine sulfoximine; DAS; diallyl sulfide; EUKA; Eukarion-134; 8-oxodG; 8-oxo-7,8-dihydro-2-deoxyg
Identification of the factors responsible for the in vitro pro-oxidant and cytotoxic activities of the olive polyphenols oleuropein and hydroxytyrosol
Keywords: Amplex® Red reagent; 10-acetyl-3,7-dihydroxyphenoxazine; DMEM/F12; Dulbecco's modified Eagle medium-F12 mixture; EBSS; earle's balanced salt solution; FBS; fetal bovine serum; FOX; ferrous oxidation-xylenol orange; H2O2; hydrogen peroxide; MEM; minim
Time series analysis of oxidative stress response patterns in HepG2: A toxicogenomics approach
Keywords: DNPH; 2,4-dinitrophenylhydrazine; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; DMPO; 5,5-dimethyl-1-pyrolline N-oxide; 8-oxo-dG; 8-oxo-2â²-deoxyguanosine; ARE; antioxidant response elements; CDF; chip definition files; DEGs; differe
Telmisartan ameliorates germ cell toxicity in the STZ-induced diabetic rat: Studies on possible molecular mechanisms
Keywords: ARBs; angiotensin receptor blocker; AT1; angiotensin II receptor type 1; NF-κB; nuclear factor kappa B; IL-6; interleukin 6; iNOS; inducible nitric oxide; TNF-α; tumor necrosis factor alpha; 8-oxo-dG; 8-oxo-7,8-dihydro-2â²-deoxyguanosine; pERK; phospho
Analysis of mutant frequencies and mutation spectra in hMTH1 knockdown TK6 cells exposed to UV radiation
Keywords: Ultraviolet radiation; Oxidative stress; Nucleotide pool; hMTH1; 8-Oxo-dG; 2-OH-dAROS, reactive oxygen species; dNTP, deoxyribonucleotide triphosphate; 8-oxo-dG, 8-oxo-2′-deoxyguanosine; 8-oxo-dGTP, 8-oxo-2′-deoxyguanosine-5′-triphosphate; 2-OH-dA, 2-hydr
8-Oxo-2′-deoxyguanosine ameliorates UVB-induced skin damage in hairless mice by scavenging reactive oxygen species and inhibiting MMP expression
Keywords: Ultraviolet B; 8-Oxo-dG; ROS; MAPKs; MMPs
Anti-CD40 Ab- or 8-oxo-dG-enhanced Treg cells reduce development of experimental autoimmune encephalomyelitis via down-regulating migration and activation of mast cells
Keywords: EAE; Anti-CD40 Ab; 8-oxo-dG; Treg cells; Mast cells; Inflammatory cytokines
Stability of acetaldehyde-derived DNA adduct in vitro
Keywords: AA; acetaldehyde; ALDH2; aldehyde dehydrogenase-2; LC/MS/MS; liquid chromatography-tandem mass spectrometry; N2-ethylidene-dG; N2-ethylidene-2â²-deoxyguanosine; N2-Et-dG; N2-ethyl-2â²-deoxyguanosine; α-Me-γ-OH-PdG; α-methyl-γ-hydroxy-1, N2-propano
Early ROS-mediated DNA damage and oxidative stress biomarkers in Monoclonal B Lymphocytosis
Keywords: Monoclonal B Lymphocytosis; Chronic lymphocytic leukaemia; Oxidative stress; 8-Oxo-dG; Antioxidants; DNA damage; F2-isoprostanes
The antioxidant and anti-inflammatory activities of tocopherols are independent of Nrf2 in mice
Keywords: γ-TmT; gamma-tocopherol-rich mixture of tocopherols; γ-T; gamma-tocopherol; Nrf2; nuclear factor (erythroid-derived 2)-like 2; Nrf2 (-/-); Nrf2 knockout; DSS; dextran sulfate sodium; AOM; azoxymethane; PGE2; prostaglandin E2; RONS; reactive oxygen and n
CommentaryAntioxidants for prostate cancer chemoprevention: Challenges and opportunities
Keywords: 8-oxo-dG; 8-oxo-2â²-deoxyguanosine; ADT; androgen-deprivation therapy; AR; androgen receptor; ARE; antioxidant response element; ATBC; Alpha-Tocopherol, Beta-Carotene; BPH; benign prostatic hyperplasia; CARET; Carotene and Retinol Efficacy Trial; CRPC; c
Intranuclear matrix metalloproteinases promote DNA damage and apoptosis induced by oxygen-glucose deprivation in neurons
Keywords: 8-oxo-dG; 8-hydroxy-2â²-dexoguanine; BBB; blood-brain barrier; BER; base excision repair; Cy3; Cyanine 3; DAPI; 4â²-6-diamidino-2-phenylindole; DMSO; dimethyl sulfoxide; dUTP; deoxyuridine triphosphate; FBS; fetal bovine serum; FITC; fluorescein isoth
Lycopene inhibits DNA damage and reduces hMTH1 mRNA expression in the liver of Mongolian gerbils treated with ferric nitrilotriacetate
Keywords: 8-Oxo-dG; 8-hydroxy-2â²-deoxyguanosine; BHT; butylated hydroxytoluene; EtBr; ethidium bromide; Fe/NTA; ferric nitrilotriacetate; HCC; hepatocellular carcinoma; hMTH; human MutT homologue; LMA; low melting point agarose; LP; lycopene; NMA; normal melting
Reduction of 8-oxodGTP in the nucleotide pool by hMTH1 leads to reduction in mutations in the human lymphoblastoid cell line TK6 exposed to UVA
Keywords: Oxidative stress; hMTH1; Mutagenesis; UVA; 8-oxo-dG; 8-OH-dG; 8-oxo-dGTP; Reactive oxygen species
Ochratoxin A reduces aflatoxin B1 induced DNA damage detected by the comet assay in Hep G2 cells
Keywords: 8-oxo-dG; 8-oxoguanine; AFB1; aflatoxin B1; AFB1-FAPY; AFB1-formamidopyrimidin; AFBO; AFB1-exo-8,9-epoxide; AP site; apirimidinic or apurinic site; CIT; citrinin; DCFH-DA; dihydrodichlorofluorescein diacetate; DON; deoxinivalenol; EFSA; European Food Safe
Occult hepatitis C virus elicits mitochondrial oxidative stress in lymphocytes and triggers PI3-kinase-mediated DNA damage response
Keywords: 8-oxo-dG; 8-oxo-2â²-deoxyguanosine; ALT; alanine transferase; ARP; aldehyde-reactive probe; CM-H2DCFDA; 5-(and-6)-chloromethyl-2â²,7â²-dichlorodihydrofluorescein diacetate acetyl ester; DCF; 2â²,7â²-dichlorofluorescin; DSB; double-strand break; EDTA;
Ellagitannins, ellagic acid and vascular health
Keywords: ACE; angiotensin converting enzyme; ACO; acyl CoA oxidase; AMPK; 5â²-AMP activated protein kinase; ApoB; apolipoprotein B; COMT; catechol ortho methyl transferase; CPT; carnitine palmitoyl transferase; CRP; C-reactive protein; CYP450; cytochrome P450; d.
DNA polymerase gamma and mitochondrial disease: Understanding the consequence of POLG mutations
Keywords: mtDNA; mitochondrial DNA; PEO; progressive external ophthalmoplegia; pol γ; DNA polymerase γ; NRTI; nucleoside reverse-transcriptase inhibitor; ad; autosomal dominant; WT; wild-type; ROS; reactive oxygen species; 8-oxo-dG; 8-oxo-7,8-dihydro-2â²-deoxygu
Oxidative damage in gill of Mytilus edulis from Merseyside, UK, and reversibility after depuration
Keywords: Mussel; Comet; Lipid peroxidation; 8-oxo-dG; SSB
Human 8-oxoguanine-DNA glycosylase 1 protein and gene are expressed more abundantly in the superficial than basal layer of human epidermis
Keywords: Skin cancer; hOGG1; DNA repair; 8-Oxo-dG; UVA; Ultraviolet; Oxidative DNA damage
Accumulation of 8-oxo-deoxyguanosine in cardiovascular tissues with the development of hypertension
Keywords: 8-Oxo-dG; MTH1; Hypertension; Aorta; Apoptosis
Lipid peroxidation-derived etheno-DNA adducts in human atherosclerotic lesions
Keywords: ANPG; alkyl-DNA-glycosylase; ApoE-KO; apolipoprotein E knockout; BPDE; benzo(a)pyrene diolepoxide; DRZ; diagonal radioactive zone; ÉdA; 1,N6-ethenodeoxyadenine; ÉdC; 3,N4-ethenodeoxycytosine; HNE; trans-4-hydroxy-2-nonenal; LOH; loss of heterozigosity;
The case for 8,5â²-cyclopurine-2â²-deoxynucleosides as endogenous DNA lesions that cause neurodegeneration in xeroderma pigmentosum
Keywords: DNA repair; Parkinson's disease; transcription; dopamine; cockayne syndrome; DeSanctis-Cacchione syndrome; BER; base excision repair; CS; Cockayne syndrome; CSF; cerebrospinal fluid; cyclo-dA; 8,5â²-cyclo-2â²-deoxyadenosine; Cyclopurine-deoxynucleosid
Arsenite and monomethylarsonous acid generate oxidative stress response in human bladder cell culture
Keywords: As (III); MMA(III); Oxidative stress; ROS; DCFDA; 8-oxo-dG
8-hydroxydeoxyguanosine suppresses NO production and COX-2 activity via Rac1/STATs signaling in LPS-induced brain microglia
Keywords: ROS; reactive oxygen species; oh8dG; 8-hydroxydeoxyguanosine; 8-oxo-dG; 8-oxo-deoxyguanosine; oh8G; 8-hydroxyguanosine; 8-oxo-G; 8-oxo-guanosine; dG; deoxyguanosine; G; guanosine; oh8dGTP; 8-hydroxydeoxyguanosine triphosphate; 8-oxo-deoxyguanosine triphos
Antioxidants prevent oxidative DNA damage and cellular transformation elicited by the over-expression of c-MYC
Keywords: ROS; Superoxide; Vitamin C; 8-Oxo-dG; Foci; Mitochondria
Methamphetamine-enhanced embryonic oxidative DNA damage and neurodevelopmental deficits
Keywords: Methamphetamine; Amphetamines; Reactive oxygen species; Oxidative DNA damage; Neurotoxicity; Neurodevelopmental deficits; Dopaminergic nerve terminals; Teratogenesis; Motor coordination; METH; methamphetamine; ROS; reactive oxygen species; GD; gestational
Senescence-associated decline in the intranuclear accumulation of hOGG1-α and impaired 8-oxo-dG repair activity in senescing normal human oral keratinocytes in vivo
Keywords: Keratinocytes; Senescence; Oxidative stress; 8-oxo-dG;
Molecular and biochemical mechanisms in teratogenesis involving reactive oxygen species
Keywords: ASA; acetylsalicylic acid; ATM; ataxia telangiectasia mutated; COX; cyclooxygenase (PHS component); CYP; cytochromes P450; ETYA; eicosatetraynoic acid; G6PD; glucose-6-phosphate dehydrogenase; GSH; glutathione; iNOS; inducible nitric oxide synthase; IR; i