Keywords: پروتئین اتصال دهنده استیل کولین; MG; myasthenia gravis; AChR; nicotinic acetylcholine receptor; ECD; extracellular domain; MIR; main immunogenic region; AChBP; acetylcholine binding protein; α-Btx; α-bungarotoxin.; Nicotinic acetylcholine receptor; Extracellular domain; Myasthenia grav
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Keywords: پروتئین اتصال دهنده استیل کولین; On-line microfluidics; Nano-liquid chromatography-mass spectrometry (nano-LC-MS); Snake venom proteome screening; Venom purification; Lymnaea stagnalis acetylcholine binding protein (Ls-AChBP); Nicotinic acetylcholine receptor; ACN; acetonitrile; AChB
Keywords: پروتئین اتصال دهنده استیل کولین; On-line microfluidics; Nano-liquid chromatography-mass spectrometry (nano-LC-MS); Snake venom proteome screening; Venomics; Lymnaea stagnalis acetylcholine binding protein (Ls-AChBP); Nicotinic acetylcholine receptor; AChBP; Acetylcholine binding prot
The binding orientation of epibatidine at α7 nACh receptors
Keywords: پروتئین اتصال دهنده استیل کولین; Cys-loop; Ion channel; Radioligand; Epibatidine; Agonist; α7 nACh; Nicotinic; Receptor; AChBP; 5-HT; 5-hydroxytryptamine; nACh; nicotinic acetylcholine; GABA; gamma-aminobutyric acid; HEK; human embryonic kidney; AChBP; acetylcholine binding protein; 5HT
Characterization of a reproducible rat EAMG model induced with various human acetylcholine receptor domains
Keywords: پروتئین اتصال دهنده استیل کولین; MG; myasthenia gravis; AChR; nicotinic acetylcholine receptor; ECD; extracellular domain; MIR; main immunogenic region; AChBP; acetylcholine binding protein; α-Btx; α-bungarotoxin; EAMG; experimental autoimmune myasthenia gravis; EMG; electromyography;
Assessment of the functionality and stability of detergent purified nAChR from Torpedo using lipidic matrixes and macroscopic electrophysiology
Keywords: پروتئین اتصال دهنده استیل کولین; nAChR-DCs; nicotinic acetylcholine receptors detergent complexes; Tc; Torpedo californica; Tm; Torpedo marmorata; PLB; planar lipid bilayer; TEVC; two electrode voltage clamp; LCP; Lipidic Cubic Phase; FC; foscholine family 12-16 carbon chain; LFC; lyso
Synthesis and biological activities of indolizine derivatives as alpha-7 nAChR agonists
Keywords: پروتئین اتصال دهنده استیل کولین; α7 nAChR; Indolizine; Agonists; SAR; Schizophrenia; ACh; acetylcholine; THF; tetrahydrofuran; DMSO; dimethylsulfoxide; CNS; central nervous system; HRMS; high resolution mass; DIPEA; diisopropylethylamine; AChBP; acetylcholine binding protein; SAR; struc
Biomolecular recognition of antagonists by α7 nicotinic acetylcholine receptor: Antagonistic mechanism and structure-activity relationships studies
Keywords: پروتئین اتصال دهنده استیل کولین; AChBP; acetylcholine binding protein; Ala; alanine; Arg; arginine; ATP; adenosine triphosphate; CNS; central nervous system; CoMFA; comparative molecular field analysis; CoMSIA; comparative molecular similarity indices analysis; Cys; cysteine; 3D-QSAR; th
Exploration of the molecular architecture of the orthosteric binding site in the α4β2 nicotinic acetylcholine receptor with analogs of 3-(dimethylamino)butyl dimethylcarbamate (DMABC) and 1-(pyridin-3-yl)-1,4-diazepane
Keywords: پروتئین اتصال دهنده استیل کولین; nACh receptor agonists; Structure-activity studies; Ls-AChBP; Ac-AChBP; Lobeline; DMABC analogs; Ac; Aplysia californica; ACh; acetylcholine; AChBP; acetylcholine binding protein; CNS; central nervous system; CDI; 1,1â²-carbonyldiimidazole; Ct; Capitel
The binding characteristics and orientation of a novel radioligand with distinct properties at 5-HT3A and 5-HT3AB receptors
Keywords: پروتئین اتصال دهنده استیل کولین; Antagonist; Cys-loop; Ion channel; Radioligand; 5-HT3; Agonist; 5-HT; 5-hydroxytryptamine; nACh; nicotinic acetylcholine; GABA; gamma-aminobutyric acid; HEK; human embryonic kidney; AChBP; acetylcholine binding protein; 5HTBP; an AChBP mutant modified to
Interactions of acetylcholine binding site residues contributing to nicotinic acetylcholine receptor gating: Role of residues Y93, Y190, K145 and D200
Keywords: پروتئین اتصال دهنده استیل کولین; ACh; acetylcholine; nAChR; nicotinic acetylcholine receptor; AChBP; acetylcholine binding protein; LBD; ligand binding domain; dTC; d-tubocurarine; DC6C; Dansyl C6 Choline; nAChR; Resting state; Desensitized state; αγ interface; αδ interface; Molecula
The pharmacological profile of ELIC, a prokaryotic GABA-gated receptor
Keywords: پروتئین اتصال دهنده استیل کولین; Cys-loop; Erwinia; Ligand-gated; Antagonist; Nicotinic; ELIC; GLIC; GABA; nACh; nicotinic acetylcholine; AChBP; acetylcholine binding protein; GABA; γ-aminobutyric acid; ELIC; Erwinia ligand-gated ion channel; GLIC; Gloeobacter ligand-gated ion channel;
The Haemonchus contortus UNC-49B subunit possesses the residues required for GABA sensitivity in homomeric and heteromeric channels
Keywords: پروتئین اتصال دهنده استیل کولین; 5-HT3; serotonin (5-hydroxytryptamine)-gated ion channel receptor; AChBP; acetylcholine binding protein; cRNA; copy RNA; LGIC; ligand-gated ion channels; MS-222; 3-aminobenzoic acid ethyl ester, methanesulphonate salt; nAChR; nicotinic acetylcholine recep
Allosteric modulators induce distinct movements at the GABA-binding site interface of the GABA-A receptor
Keywords: پروتئین اتصال دهنده استیل کولین; GABAA receptor; Benzodiazepine efficacy; Oocyte expression; Allosteric modulation; Pentobarbital; GABA; BZD; benzodiazepine; GABAR; GABA-A receptor; MTSEA-Biotin; N-biotinaminoethyl methanethiosulfonate; MTSES; 2-sulfonatoethyl methanethiosulfonate; DMCM;
In silico characterization of cytisinoids docked into an acetylcholine binding protein
Keywords: پروتئین اتصال دهنده استیل کولین; Nicotinic acetylcholine receptors; Acetylcholine binding protein; Cytisinoids; Docking;
Development of surface plasmon resonance biosensor assays for primary and secondary screening of acetylcholine binding protein ligands
Keywords: پروتئین اتصال دهنده استیل کولین; Surface plasmon resonance; Biosensor; Nicotinic acetylcholine receptor; Acetylcholine binding protein; Sequential assay; Screening
Docking to flexible nicotinic acetylcholine receptors: A validation study using the acetylcholine binding protein
Keywords: پروتئین اتصال دهنده استیل کولین; Protein flexibility; Molecular docking; Ensemble generation; Nicotinic; Acetylcholine receptors; nAChR; Acetylcholine binding protein; AChBP
Bis-neonicotinoid insecticides: Observed and predicted binding interactions with the nicotinic receptor
Keywords: پروتئین اتصال دهنده استیل کولین; Acetylcholine binding protein; Bis-neonicotinoid insecticides; Imidacloprid; Nicotinic acetylcholine receptor
Combined roles of loops C and D in the interactions of a neonicotinoid insecticide imidacloprid with the α4β2 nicotinic acetylcholine receptor
Keywords: پروتئین اتصال دهنده استیل کولین; Neonicotinoids; Imidacloprid; Nicotinic acetylcholine receptor; Ion channels; Ligand binding domain; Chicken α4β2 nicotinic receptor; Homology modeling; Acetylcholine binding protein; ACh; acetylcholine; nAChR; nicotinic acetylcholine receptor; EC50; co
Insight in nAChR subtype selectivity from AChBP crystal structures
Keywords: پروتئین اتصال دهنده استیل کولین; Nicotinic acetylcholine receptor selectivity; Acetylcholine binding protein; X-ray structure
A virtual screening study of the acetylcholine binding protein using a relaxed–complex approach
Keywords: پروتئین اتصال دهنده استیل کولین; Acetylcholine binding protein; Nicotinic acetylcholine receptor; Relaxed–complex; Molecular dynamics; Docking; Virtual screening
Rhesus monkey α7 nicotinic acetylcholine receptors: Comparisons to human α7 receptors expressed in Xenopus oocytes
Keywords: پروتئین اتصال دهنده استیل کولین; Voltage-clamp; Alzheimer's disease; Acetylcholine binding protein; α7 nicotinic receptor;
Activation of ionotropic receptors and thermodynamics of binding
Keywords: پروتئین اتصال دهنده استیل کولین; AChBP; acetylcholine binding protein; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole; ÎCp; heat capacity change; ÎH; change in enthalpy; ÎS; change in entropy; ÎG; change in free energy; GABAA; A-type γ-aminobutyric acid; MPPB; 1-methyl-5-phenyl-5-pro