An induction effect of heat shock on the transcript of globular acetylcholinesterase in NG108-15 cells
Keywords: آهی; AChE; PRiMA; Heat shock; Transcription; Molecular form
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Development of new acetylcholinesterase reactivators: Molecular modeling versus in vitro data
Keywords: آهی; QM/MM; quantum mechanic/molecular mechanics; AChE; acetylcholinesterase; MmAChE; Mus musculus acetylcholinesterase; DFT; Density Functional Theory; TS; transition state; Acetylcholinesterase; QM/MM; Chemical mechanism of reactivation; Neurotoxic agents;
Kinetic analysis of interactions of different sarin and tabun analogues with human acetylcholinesterase and oximes: Is there a structure–activity relationship?
Keywords: آهی; Organophosphorus compounds; Oximes; AChE; Reactivation; Structure–activity relationship
Identification of non-alkaloid acetylcholinesterase inhibitors from Ferulago campestris (Besser) Grecescu (Apiaceae)
Keywords: آهی; Ferulago campestris; Daucane derivative; Ache; Bioassay-guided fractionation
Efficient hydrolysis of the chemical warfare nerve agent tabun by recombinant and purified human and rabbit serum paraoxonase 1
Keywords: آهی; PON1; paraoxonase 1; HPON1; human PON1; RPON1; rabbit PON1; rePON1; recombinant PON1; OP; organophosphate; CWNA; chemical warfare nerve agent; DFP; diisopropylfluorophosphate; CPO; chloropyrifos oxon; AChE; acetylcholinesterase; BChE; butyrylcholinesteras
The ameliorating effect of the extract of the flower of Prunella vulgaris var. lilacina on drug-induced memory impairments in mice
Keywords: آهی; AChE; acetylcholinesterase; AD; Alzheimer's disease; CREB; cAMP response element-binding protein; EEPV; the ethanolic extract of the flower of Prunella vulgaris var. lilacina; ERK; extracellular signal-regulated kinase; NMDA; N-methyl-d-aspartate; LTP;
Evaluation of medical countermeasures against organophosphorus compounds: The value of experimental data and computer simulations
Keywords: آهی; Organophosphorus compounds; Oximes; AChE; Reactivation; Computer model
PRiMA directs a restricted localization of tetrameric AChE at synapses
Keywords: آهی; AChE; PRiMA; Molecular form; Synapse; Lipid raft
In vitro and in vivo interactions of aluminum on NTPDase and AChE activities in lymphocytes of rats
Keywords: آهی; Aluminum; Lymphocytes; NTPDase; AChE; In vitro; In vivo
Fluoride-induced brain damages in suckling mice
Keywords: آهی; AChE; Cerebellum; Cerebrum; Laminin; TBARS; tGSH; SOD; GPx; CAT; Suckling mice
Acute effects of benzo[a]pyrene on digestive gland enzymatic biomarkers and DNA damage on mussel Mytilus galloprovincialis
Keywords: آهی; Acute exposure; Benzo[a]pyrene; BPH; GST; CAT; AChE; DNA damage
The use of Fulvia fragilis (Mollusca: Cardiidae) in the biomonitoring of Bizerta lagoon: A mutimarkers approach
Keywords: آهی; Fulvia fragilis; Bizerta lagoon; Biomarkers; GSH; CAT; GST; MDA; AChE
Chemical markers’ fishing and knockout for holistic activity and interaction evaluation of the components in herbal medicines
Keywords: آهی; Two-dimensional turbulent flow chromatography/LC–MS; Chemical markers’ fishing and knockout; Holistic evaluation; Interaction; AChE; Herbal medicine; Lycoris radiata
Molecular basis of inhibition of substrate hydrolysis by a ligand bound to the peripheral site of acetylcholinesterase
Keywords: آهی; AChE; acetylcholinesterase; ATMA; 3-(acetamido)-N,N,N-trimethylanilinium; DTNB; 5,5â²-dithiobis-(2-nitrobenzoic acid); M7C; N-methyl(7-dimethylcarbamoxy)quinolinium iodide; TcAChE; AChE from Torpedo californica; Acetylcholinesterase; Peripheral site; Thi
Chronic administration of troxerutin protects mouse brain against d-galactose-induced impairment of cholinergic system
Keywords: آهی; Troxerutin; d-Galactose; ROS; Cholinergic system; AchE; nAchRα7
Brain acetylcholinesterase, malondialdehyde and reduced glutathione as biomarkers of continuous exposure of tench, Tinca tinca, to carbofuran or deltamethrin
Keywords: آهی; Pesticide; AChE; Oxidative stress; Fish; Biomarker; Carbofuran; Deltamethrin
Baculovirus expression, biochemical characterization and organophosphate sensitivity of rBmAChE1, rBmAChE2, and rBmAChE3 of Rhipicephalus (Boophilus) microplus
Keywords: آهی; Acetylcholinesterase; AChE; Cattle fever tick; Acaricide resistance; Acari; Ixodidae
Prevalence of musculoskeletal pain in the general Swedish population from 1968 to 2002: Age, period, and cohort patterns
Keywords: آهی; Musculoskeletal; Pain; Ache; Trends; Age; Period; Cohort;
Selective recognition and elimination of nicotinic acetylcholine receptor-reactive B cells by a recombinant fusion protein AChR-Fc in myasthenia gravis in vitro
Keywords: آهی; AChE; acetylcholinesterase; AChR; nicotinic acetylcholine receptor; ANOVA; one-way analysis of variance; BCR; B cell receptor; BrdU; bromodeoxyuridine; EAMG; experimental autoimmune myasthenia gravis; ELISA; enzyme-linked immunosorbent assay; FACS; fluore
Synergism of resistance to phosalone and comparison of kinetic properties of acetylcholinesterase from four field populations and a susceptible strain of Colorado potato beetle
Keywords: آهی; Colorado potato beetle; AChE; Susceptibility; Inhibition; Synergism
Biomarker responses in Solea senegalensis exposed to sodium hypochlorite used as antifouling
Keywords: آهی; AChE; acetylcholinesterase (EC 3.1.1.7); CAT; catalase (EC 1.11.1.6); CbE; carboxylesterase (EC 3.1.1.1.); EROD; ethoxyresorufin O-deethylase; GR; glutathione reductase (EC 1.6.4.2); GPX; glutathione peroxidase (EC 1.11.1.9); GST; glutathione S-transferas
Co-localization of PRiMA with acetylcholinesterase in cholinergic neurons of rat brain: An immunocytochemical study
Keywords: آهی; 3n; oculomotor nucleus; Aβ; amyloid beta peptide; AChE; acetylcholinesterase; ChAT; choline acetyltransferase; EM; electron microscope; ER; endoplasmic reticulum; GAD67; glutamic acid decarboxylase 67; LB; lamellar body; MS/DB; medial septum diagonal ban
Using a phylogenetic approach to selection of target plants in drug discovery of acetylcholinesterase inhibiting alkaloids in Amaryllidaceae tribe Galantheae
Keywords: آهی; Amaryllidaceae; Galantheae; AChE; Alkaloids; Phylogeny; Galanthus; DNA; Drug discovery
Multiple biomarkers of pollution effects in caged mussels on the Greek coastline
Keywords: آهی; Biomarkers; AchE; CAT; GST; MTs; RNA:DNA ratio; Mytilus galloprovincialis; Mediterranean
Neurodegeneration, Neuroprotection, and Disease-Oriented NeuroscienceResearch PaperCurcuminoids enhance memory in an amyloid-infused rat model of Alzheimer's disease
Keywords: آهی; curcumin; bisdemethoxycurcumin; demethoxycurcumin; genes; memory; hippocampus; Aβ; amyloid peptide; AChE; acetylcholinesterase; AD; Alzheimer's disease; LTP; long term potentiation; NMDA; N-methyl-d-aspartate; PSD-95; post synaptic density protein-95; RT
Multipotent drugs with cholinergic and neuroprotective properties for the treatment of Alzheimer and neuronal vascular diseases. I. Synthesis, biological assessment, and molecular modeling of simple and readily available 2-aminopyridine-, and 2-chloropyri
Keywords: آهی; 2-Aminopyridine; 2-Chloropyridines; AChE; BuChE; Kinetic analysis; Inhibition mechanism; Neuroprotection; Molecular modeling; Alzheimer’s disease; Neuronal vascular diseases
Targeting Alzheimer’s disease: Novel indanone hybrids bearing a pharmacophoric fragment of AP2238
Keywords: آهی; Alzheimer’s disease; AChE; Aβ inhibition; Indanone; Hybrid molecules
Genomic analysis of the carboxylesterases: Identification and classification of novel forms
Keywords: آهی; AADAC; arylacetamide deacetylase; AChE; acetylcholinesterase; BChE; butyrylcholinesterase; CAUXIN; carboxylesterase-like urinary excreted protein; CE; carboxylesterase; Carboxylesterase; Serine hydrolase; Nomenclature; Xenobiotic metabolism; Genome;
Single and combined effects of hypoxia and contaminated sediments on the amphipod Monoporeia affinis in laboratory toxicity bioassays based on multiple biomarkers
Keywords: آهی; AChE; Antioxidant enzymes; Contaminated sediments; DNA strand breaks; Hypoxia; Multivariate analysis; Oxidative stress biomarkers
Analysis of motor function modulated by cholinergic neurons in planarian dugesia japonica
Keywords: آهی; cholinergic neurons; physostigmine; neural network; muscle contraction behavior; neuroregeneration; planarian; ACh; acetylcholine; AChE; acetylcholinesterase; AP; alkaline phosphatase; BCIP; 5-bromo-4-chloro-3-indolyl-phosphate; ChAT; choline acetyltransf
Heterogeneous dopamine populations project to specific subregions of the primate amygdala
Keywords: آهی; extended amygdala; ventral tegmental area; retrorubral field; dorsal tier; ventral tier; substantia nigra; III N; cranial nerve III; A8-RRF; A8-retrorubral field; A9-dt; A9-dorsal tier of substantia nigra; A9-vt; A9-ventral tier of substantia nigra; A10-V
Dendrimers and derivatives as a potential therapeutic tool in regenerative medicine strategies-A review
Keywords: آهی; 2-AS; 12-(9-anthroyloxy) stearic acid; 2-D; two-dimensional; 3-D; three-dimensional; 3-TC; lamivudine; 5-ASA; 5-aminosalicylic acid; Ac; acetylated; AChE; acetylcholinesterase; AF; alexaFluor; AFM; atomic force microscopy; ATRP; atom transfer radical poly
Novel acetylcholinesterase inhibitors: Synthesis and structure-activity relationships of phthalimide alkyloxyphenyl N,N-dimethylcarbamate derivatives
Keywords: آهی; Carbamate insecticides; AChE; Multiple binding sites; Phthalimide alkyloxyphenyl N,N-dimethylcarbamate; Inhibitory activity; Structure-activity relationship;
Rational design and synthesis of highly potent anti-acetylcholinesterase activity huperzine A derivatives
Keywords: آهی; Alzheimer’s disease; Hupzine A; AChE; Docking study
In-vitro regeneration of sarin inhibited electric eel acetylcholinesterase by bis-pyridinium oximes bearing xylene linker
Keywords: آهی; Bis-pyridinium oximes; Reactivators; 2-PAM; Organophosphorus nerve agents; Sarin; Acetylcholinesterase; Xylene linkers; AChE; acetylcholinesterase; 2-PAM; 2-(hydroxyiminomethyl)-1-methylpyridinium chloride;
Sensitivity of young rats to nicotine exposure: Physiological and biochemical parameters
Keywords: آهی; Nicotine; PBG-synthase; Glucose; Glycogen; AChE; Plasma cotinine; Young rats
Active site directed docking studies: Synthesis and pharmacological evaluation of cis-2,6-dimethyl piperidine sulfonamides as inhibitors of acetylcholinesterase
Keywords: آهی; Alzheimer's diseases; AChE; Docking
Toxicological and metabolic parameters of the teleost fish (Leporinus obtusidens) in response to commercial herbicides containing clomazone and propanil
Keywords: آهی; AChE; Herbicides; Leporinus obtusidens; Metabolism; Oxidative stress;
Blockade of GABA(B) receptors completely reverses age-related learning impairment
Keywords: آهی; CGP55845; aging; GABA(B) receptor; cognitive enhancement; odor; learning; AChE; acetylcholinesterase; MCI; mild cognitive impairments; SD; standard deviation;
Paeonol attenuates neurotoxicity and ameliorates cognitive impairment induced by d-galactose in ICR mice
Keywords: آهی; Ach; acetylcholine; AChe; acetylcholine esterase; D-gal; d-galactose; DTNB; dithio-bis-nitrobenzoic acid; GPx; glutathione peroxidase; GSH; reduced glutathione; MC; Moutan cortex of Paeonia suffruticosa Andrews; MDA; malondialdehyde; Na+; K+-ATPase, Na+,
RNAi of ace1 and ace2 in Blattella germanica reveals their differential contribution to acetylcholinesterase activity and sensitivity to insecticides
Keywords: آهی; AChE; RNA interference; ace genes; Cockroach; Insecticides
Extreme variability in the formation of chlorpyrifos oxon (CPO) in patients poisoned by chlorpyrifos (CPF)
Keywords: آهی; AChE; acetylcholinesterase (EC 3.1.1.7); BChE; butyrylcholinesterase (EC 3.1.1.8); CPF; chlorpyrifos; CPO; chlorpyrifos oxon; PON 1; paraoxonase 1 (EC 3.1.8.1); RBC; red blood cells; Organophosphorus; Chlorpyrifos; Poisoning; Toxicokinetics; Pralidoxime;
Neurophysiological alterations in Caenorhabditis elegans exposed to dichlorvos, an organophosphorus insecticide
Keywords: آهی; Caenorhabditis elegans; Dichlorvos; AChE; ACh; Paralysis; Feeding; Nose contraction
Pre-treatment with ebselen and vitamin E modulate acetylcholinesterase activity: interaction with demyelinating agents
Keywords: آهی; Ethidium bromide; AChE; Rat; Demyelination; Vitamin E; Ebselen
Recombinant expression and biochemical characterization of the catalytic domain of acetylcholinesterase-1 from the African malaria mosquito, Anopheles gambiae
Keywords: آهی; Insecticide resistance; Mosquito; Malaria; Organophosphate; Carbamate; Cholinergic synapse; AChE; acetylcholinesterase; ATC; acetylthiocholine iodide; AβMTC; acetyl-(β-methyl)thiocholine iodide; PTC; propionylthiocholine iodide; BTC; butyrylthiocholine
Two-dimensional turbulent flow chromatography coupled on-line to liquid chromatography-mass spectrometry for solution-based ligand screening against multiple proteins
Keywords: آهی; On-line bioseparation/chemical analysis strategy; Two-dimensional; Turbulent flow chromatography; Ligand screening; AChE; BChE;
Catalpol ameliorates beta amyloid-induced degeneration of cholinergic neurons by elevating brain-derived neurotrophic factors
Keywords: آهی; Aβ25-35; learning and memory; muscarinic receptor; BDNF; cholinergic neurons; catalpol; AChE; acetylcholinesterase; AcTC; acetylthiocholine ester; AD; Alzheimer's disease; Aβ; beta-amyloid peptide; BDNF; brain-derived neurotrophic factor; ChAT; cholin
Soman induces ictogenesis in the amygdala and interictal activity in the hippocampus that are blocked by a GluR5 kainate receptor antagonist in vitro
Keywords: آهی; basolateral amygdala; CA1 area; ictogenesis; GluR5 receptors; nerve agents; ACh; acetylcholine; AChE; acetylcholinesterase; ACSF; artificial cerebrospinal fluid; BLA; basolateral nucleus of the amygdala; CNQX; 6-cyano-7-nitroquinoxaline-2,3-dione; GluR5KR
Transcriptional regulation of proline-rich membrane anchor (PRiMA) of globular form acetylcholinesterase in neuron: An inductive effect of neuron differentiation
Keywords: آهی; PRiMA; proline rich membrane anchor; AChE; acetylcholinesterase; MAP; mitogen-activated protein; cAMP; 3â²-5â²-cyclic adenosine monophosphate; ERK; extracellular signal-regulated kinase; MEK; mitogen-activate protein kinase; AChE; PRiMA; G4 enzyme; Prom
Regional and laminar distribution of the vesicular glutamate transporter, VGluT2, in the macaque monkey auditory cortex
Keywords: آهی; A1; auditory area 1 (core); AChE; acetylcholinesterase; AL; anterolateral area (belt); CB; calbindin; CL; caudolateral area (belt); CM; caudomedial area (belt); CO; cytochrome oxidase; CPB; caudal parabelt area (parabelt); CS; central sulcus; Ins; insula;