دانلود مقالات ISI درباره AD، بیماری آلزایمر + ترجمه فارسی

Platelet serotonin concentration and monoamine oxidase type B activity in female patients in early, middle and late phase of Alzheimer's disease

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; ANOVA, One-Way Analysis of Variance; HPLC, high pressure liquid chromatography; MAO, monoamine oxidase; MMSE, Mini Mental State Examination; NINDS-ADRDA, National Institute of Neurologic and Communicative Disorders and Stroke and

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Intracellular amyloid induces impairments on electrophysiological properties of cultured human neurons

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; APP, amyloid precursor protein; ANOVA, analysis of variances; Aβ, amyloid β; eAβ, extracellular amyloid β; iAβ, intracellular amyloid β; DMEM, Dulbecco's modified Eagle's medium; ELISA, enzyme-linked immunosorbent assay; FBS, feta

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Downregulation of LPR1 at the blood–brain barrier in streptozotocin-induced diabetic mice

Keywords: AD، بیماری آلزایمر; Low-density lipoprotein receptor related protein; Amyloid-β peptide; Blood–brain barrier; Diabetes mellitusDM, diabetes mellitus; AD, Alzheimer's disease; STZ, streptozotocin; LRP1, low-density lipoprotein receptor related protein 1; Aβ, amyloid-β peptide

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Time-course of blood–brain barrier disruption in senescence-accelerated mouse prone 8 (SAMP8) mice

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; APP, amyloid precursor protein; BBB, blood–brain barrier; EB, Evans blue; HRP, horseradish peroxidase; ME, mean extravasation; PBS, phosphate buffered saline; PFA, p-formaldehyde; ROI, region of interest; SAMP8, senescence-acceler

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Triosephosphate isomerase deficiency: New insights into an enigmatic disease

Keywords: AD، بیماری آلزایمر; TPI, triosephosphate isomerase; DHAP, dihydroxyacetone phosphate; AD, Alzheimer's disease; AGE, advanced glycation end product; Aβ, amyloid β-peptideNeurodegeneration; Enzymopathy; Conformational disease; Glycolysis; Methylglyoxal; Advanced glycation end

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

The role of kynurenines in disorders of the central nervous system: Possibilities for neuroprotection

Keywords: AD، بیماری آلزایمر; 3-HA, 3-hydroxyanthranilic acid; 3-HK, 3-hydroxykynurenine; AD, Alzheimer's disease; AMPA, alpha-amino-3-hydroxy-5-methylisoxazole-4-proprionic acid; ANA, anthranilic acid; BBB, blood-brain barrier; CSD, cortical spreading depression; EAA, excitatory amin

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Protective effect of curcumin (Curcuma longa), against aluminium toxicity: Possible behavioral and biochemical alterations in rats

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; DNA, deoxyribonucleic acid; ROS, reactive oxygen species; DTNB, dithiobisnitrobenzoic acid; H2O2, hydrogen peroxide; GSH, reduced glutathione; LOX, lipooxygeanse; NO, nitric oxideAluminium; Alzheimer's disease; Oxidative stress; C

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Attenuation of oxidative neuronal cell death by coffee phenolic phytochemicals

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; Aβ, amyloid β; CGA, chlorogenic acid; DAPI, 4,6-diamidino-2-phenylindole; DCFH-DA, 2′,7′-dichlorofluorescin diacetate; H2O2, hydrogen peroxide; IDC, instant decaffeinated coffee; JNK, c-Jun N-terminal protein kinase; MAPK, mitogen

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Validation of an 18F-labeled biphenylalkyne as a positron emission tomography imaging agent for β-amyloid plaques

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; Aβ, β-amyloid; FDDNP, 2-(1-[6-[(2-fluoroethyl)methyl-amino]-2-naphthyl]ethylidend)malononitrile; IMPY, 6-iodo-2-(4′-dimethylamino-)phenyl-imidazo[1,2-a]pyridine; PET, positron emission tomography; PIB, 2-(4′-(methylaminophenyl)-6-

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Modulation of brain-derived neurotrophic factor as a potential neuroprotective mechanism of action of omega-3 fatty acids in a parkinsonian animal model

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; BBB, blood brain barrier; BDNF, brain-derived neurotrophic factor; CNS, central nervous system; DA, dopamine; DAergic, dopaminergic; DHA, docosahexaenoic acid; DL, dorsolateral; DM, dorsomedial; GDNF, glial cell line-derived neuro

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Memory improvement in ibotenic acid induced model rats by extracts of Scutellaria baicalensis

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; Ibo model, ibotenic acid induced memory deficient model; ChAT, choline acetyl transferase; GAD65/67, glutamic acid decarboxylase 65/67; NMDA, N-methyl-d-aspartic acid; AMPA, alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Mechanism of bis(7)-tacrine inhibition of GABA-activated current in cultured rat hippocampal neurons

Keywords: AD، بیماری آلزایمر; GABAA receptor; Acetylcholinesterase inhibitor; Competitive inhibition; pA2; KineticsACh, acetylcholine; AChE, acetylcholinesterase; AD, Alzheimer's disease; ANOVA, analysis of variance; Bis(7)-tacrine, 1,7-N-heptylene-bis-9,9′-amino-1,2,3,4-tetrahydroacr

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Trafficking, a key player in regulated intramembrane proteolysis

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; Aph-1, anterior pharynx defective protein-1; APP, amyloid precursor protein; DRM, detergent-resistant membrane; ER, endoplasmic reticulum; GGA, Golgi-localized γ-ear-containing Arf-binding protein; I-CLiP, intramembrane cleaving p

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Function, regulation and therapeutic properties of β-secretase (BACE1)

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; ADAM, a disintegrin and metalloprotease; APP, amyloid precursor protein; Aβ, amyloid-β-peptide; BACE1, β-site APP cleaving enzyme 1; NRG1, Neuregulin-1; PS, presenilinAlzheimer's disease; Aβ; APP; BACE1; Neuregulin; Secretase

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

NAP protects memory, increases soluble tau and reduces tau hyperphosphorylation in a tauopathy model

Keywords: AD، بیماری آلزایمر; NAP, NAPVSIPQ; AD, Alzheimer's disease; ADNP, activity-dependent neuroprotective protein; MWM, Morris water maze; htau, human tau; DM-Tau-tg, double mutant tau transgenic mice; NFTs, neurofibrillary tangles; w.t., wild-typeTau; Tauopathy; NAP; Neurodegene

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Abnormalities of the uncinate fasciculus and posterior cingulate fasciculus in mild cognitive impairment and early Alzheimer's disease: A diffusion tensor tractography study

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; DTI, diffusion tensor imaging; DTT, diffusion tensor tractography; MCI, mild cognitive impairment; ROI, region of interest; MMSE, mini-mental state examination; ADAS-Jcog., Alzheimer's disease assessment scale-cognitive component-

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Autophagy in Caenorhabditis elegans

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; ALS, amyotrophic lateral sclerosis; Atg, autophagy-related gene; APP, amyloid precursor protein; BH3, Bcl-2 homology region 3; Daf, dauer formation; Deg, degeneration; FOXO, Forkhead box O family of transcription factors; GABA, γ-

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

A single dose of passive immunotherapy has extended benefits on synapses and neurites in an Alzheimer's disease mouse model

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; Aβ, amyloid-beta peptide; NGS, normal goat serumAlzheimer's; Immunotherapy; Amyloid; Senile plaque; Synaptic plasticity

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Membrane interactions of a self-assembling model peptide that mimics the self-association, structure and toxicity of Aβ(1–40)

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; Aβ, β-amyloid peptide; POPC, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine; POPG, 1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-rac-1-glycerol [sodium salt]; DMPC, 1, 2-dimyristoyl-3-sn-phosphatidylcholine; LUV, large unilamellar v

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Peoniflorin attentuates Aβ(1–42)-mediated neurotoxicity by regulating calcium homeostasis and ameliorating oxidative stress in hippocampus of rats

Keywords: AD، بیماری آلزایمر; Aβ(1–42), β-amyloid peptide (1–42); AD, Alzheimer's disease; [Ca2+]i, intracellular free calcium concentration; CP, carbonyl protein; DNPH, dinitrophenylhydrazone; DTNB, dithio-bis-nitrobenzoic acid; GSH, reduced glutathione; MDA, malondialdehyde; MWM, Mo

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Activation of PKCδ and ERK1/2 in the sensitivity to UV-induced apoptosis of human cells harboring 4977 bp deletion of mitochondrial DNA

Keywords: AD، بیماری آلزایمر; 8-OHdG, 8-hydroxy 2′-deoxyguanosine; AD, Alzheimer's disease; CPEO, chronic progressive external ophthalmoplegia; H2O2,, hydrogen peroxide; LHON, Leber's hereditary optic neuropathy; MAPK, mitogen-activated protein kinase; MELAS, mitochondrial myopathy, e

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Transcriptional regulation of the murine Presenilin-2 gene reveals similarities and differences to its human orthologue

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; Aβ, amyloid beta; APP, amyloid precursor protein; CNS, central nervous system; EMSA, electrophoretic mobility shift assay; FAD, familial Alzheimer's disease; FBS, fetal bovine serum; HEK, human embryonal kidney; LTK, leukocyte tyr

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Stimulus pattern dependence of the Alzheimer's disease amyloid-β 42 peptide's inhibition of long term potentiation in mouse hippocampal slices

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's Disease; Aβ42, amyloid beta 1–42; ACSF, artificial cerebral spinal fluid; fEPSP, field excitatory post synaptic potentiation; HFIP, hexafluoroisopropanol; HFS, high frequency stimulation; Hz, hertz; LTP, long term potentiation; PTP, post t

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Transcriptional profiles of receptors and transporters involved in brain cholesterol homeostasis at the blood–brain barrier: Use of an in vitro model

Keywords: AD، بیماری آلزایمر; ABCA, ATP-binding cassette subfamily A; ABCG, ATP-binding cassette subfamily G; AD, Alzheimer's disease; Aβ peptide, amyloid β peptide; Apo, Apolipoprotein; BBB, blood–brain barrier; BCECs, brain capillary endothelial cells; CNS, central nervous system; H

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Alzheimer's-associated Aβ oligomers show altered structure, immunoreactivity and synaptotoxicity with low doses of oleocanthal

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; ADDLs, Aβ-derived diffusible ligands; oAβs, oligomeric Aβ; OC, oleocanthal; Aβ-OC, ADDLs formed in the presence of OC; ADDL+OC, preformed ADDLs treated with OCAlzheimer's disease; Amyloid beta; Oligomer; Olive oil; Synapse

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Ganglioside GM1 binding the N-terminus of amyloid precursor protein

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; Aβ, β-amyloid peptide; APP, amyloid β-protein precursor; APPs, secreted APP derivatives; APP-NTFs, APP N-terminal fragments; GAL-CER, gal-ceramide; CTB, cholera toxin B subunit; anti-APPCT, the anti-C-terminal APP polyclonal antib

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Assessing neuronal networks: Understanding Alzheimer's disease

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; ADC, apparent diffusion coefficient; APP, amyloid precursor protein; DMN, default mode network; DTI, diffusion tensor imaging; EEG, electroencephalographic; EMEA, European Medicines Agency; FA, fractional anisotropy; FDA, Federal

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Calpain activates caspase-8 in neuron-like differentiated PC12 cells via the amyloid-β-peptide and CD95 pathways

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; α-CD95, anti-CD95 antibody; Aβ, amyloid-β-peptide; APP, amyloid precursor protein; BAPTA, BAPTA-AM (1,2-Bis-(o-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid tetraacetoxymethyl ester); DISC, death-inducing signaling complex; DMEM,

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Zinc and copper modulate Alzheimer Aβ levels in human cerebrospinal fluid

Keywords: AD، بیماری آلزایمر; Aβ42, β-amyloid ending at residue 42; AD, Alzheimer's disease; APP, amyloid protein precursor; APLP2, amyloid precursor-like protein 2; CAA, congophilic amyloid angiopathy; CERAD, consortium to establish a registry for Alzheimer's disease; CI, confidence

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Huperzine A protects isolated rat brain mitochondria against β-amyloid peptide

Keywords: AD، بیماری آلزایمر; Aβ, β-amyloid peptide; AD, Alzheimer's disease; α-KGDHC, α-ketoglutarate dehydrogenase complex; FCCP, cyanide-p-trifluoromethoxyphenyl hydrazone; H2-DCFDA, dichlorodihydrofluorescein diacetate; HupA, huperzine A; MPT, mitochondrial permeability transition

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Aβ(1-40) Fibril Polymorphism Implies Diverse Interaction Patterns in Amyloid Fibrils

Keywords: AD، بیماری آلزایمر; Aβ, amyloid-β peptide; AD, Alzheimer's disease; cryo-EM, electron cryo-microscopy; TEM, transmission electron microscopyamyloid; neurodegeneration; prion; protein folding; structure

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Regional brain metabolism with cytochrome c oxidase histochemistry in a PS1/A246E mouse model of autosomal dominant Alzheimer's disease: Correlations with behavior and oxidative stress

Keywords: AD، بیماری آلزایمر; Aβ, beta-amyloid; AChE, acetylcholinesterase; AD, Alzheimer's disease; APP, β-amyloid precursor protein; COX, cytochrome c oxidase; DAB, diaminobenzidine; PBS, phosphate buffer saline; PS1, presenilin-1; 8-OHdG, 8-hydroxy-2-deoxyguanosineNeuronal metaboli

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Smad2 isoforms are differentially expressed during mouse brain development and aging

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; DAB, 3,3′-diaminobenzidine; MH1/2, Mad homology domain 1/2; PBS, phosphate-buffered saline; TBS, Tris-buffered saline; TGFβ1, transforming growth factor β1; Smad2(Δexon3), Smad2 missing exon 3; Smad2(FL), full length Smad2; Smad2(

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

A cog in cognition: How the α7 nicotinic acetylcholine receptor is geared towards improving cognitive deficits

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; AEP, auditory evoked potential; DAT, dementia of Alzheimer type; DHβE, dihydro-beta-erythroidine; EEG, electroencephalography; ERP, event-related potential; GABA, gamma-aminobutyric acid; MATRICS, Measurement and Treatment Researc

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Circulating insulin-like growth factor I and cognitive function: Neuromodulation throughout the lifespan

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; ALS, amyotrophic lateral sclerosis; BBB, blood–brain barrier; GH, growth hormone; GHRH, growth hormone releasing hormone; IGF-I, insulin-like growth factor-I; IGF-IR, insulin-like growth factor receptor; IGFBP3, insulin-like growt

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Kinetic partitioning between aggregation and vesicle permeabilization by modified ADan

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's Disease; DLS, Dynamic light scattering; DOPC, 1,2-Dioleoyl-sn-glycero-3-phosphocoline; DOPG, 1,2-Dioleoyl-sn-glycero-3-[phospho-rac-(1-glycerol)]; FDD, Familial Danish Dementia; IAPP, Islet Amyloid PolypeptideFamilial Danish Dementia; Non-

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Resveratrol inhibits beta-amyloid oligomeric cytotoxicity but does not prevent oligomer formation

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; Aβ, beta-amyloid peptide; fAβ, beta-amyloid fibril; ThT, thioflavin T; Res, resveratrol; SDS-PAGE, sodium dodecyl sulfate-polyacrylamide gel electrophoresis; CD, circular dichroism; TEM, transmission electron microscope; MTT, 3-(4

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Influence of age on aluminum induced lipid peroxidation and neurolipofuscin in frontal cortex of rat brain: A behavioral, biochemical and ultrastructural study

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's Disease; Al, Aluminum; CD, conjugated dienes; CAT, Catalase; GSHPx, Glutathione Peroxidase; SOD, Superoxide dismutase; LF, Lipofuscin; TP, Total Proteins; TL, Total Lipid; PC, Protein Carbonyl; LPO, Lipid peroxidation; LOOH, Lipid hydroper

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Galantamine inhibits β-amyloid aggregation and cytotoxicity

Keywords: AD، بیماری آلزایمر; Aβ, β-Amyloid peptide; NMR, Nuclear magnetic resonance; AD, Alzheimer's disease; LDH, Lactate dehydrogenase; AchE, Acetyl-cholinesterase; MTT, Methylthiazoletetrazolium; Tris, Tri(hydroxymethyl)amino-methane; EM, Electron microscopyAmyloid oligomers; Gala

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Biochemical characterization of tau protein and its associated syndapin 1 and protein kinase Cɛ for their functional regulation in rat brain

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; CDK5, cyclin-dependent kinase 5; CH-3S, cholesterol-3-sulfate; CK1, casein kinase 1; DTT, dithiothreitol; GSK-3β, glycogen synthase kinase-3β; NFT, neurofibrillary tangle; nPKC, novel Ca2+-independent and diacylglycerol-dependent

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Evaluation of the effects of vitamin A supplementation on adult rat substantia nigra and striatum redox and bioenergetic states: Mitochondrial impairment, increased 3-nitrotyrosine and α-synuclein, but decreased D2 receptor contents

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; CNS, central nervous system; D2R, dopamine receptor 2; GSH, reduced glutathione; GST, glutathione-S-transferase; METC, mitochondrial electron transfer chain; NO•, nitric oxide; •NO2, nitrogen dioxide radical; O2−•, superoxide anio

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Cholinergic depletion of the medial septum followed by phase shifting does not impair memory or rest–activity rhythms measured under standard light/dark conditions in rats

Keywords: AD، بیماری آلزایمر; ACh, acetylcholine; AChE, acetylcholinesterase; AD, Alzheimer's disease; ANOVA, analysis of variance; ChAT, choline acetyltransferase; DAB, diaminobenzidine; IgG-SAP, 192 IgG Saporin; MS/VDM, medial septum and vertical limb of the diagonal band of Broca;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

The Structure of Aβ42 C-Terminal Fragments Probed by a Combined Experimental and Theoretical Study

Keywords: AD، بیماری آلزایمر; Aβ, amyloid β-protein; CTF, C-terminal fragment; AD, Alzheimer's disease; REMD, replica exchange molecular dynamics; IM-MS, ion mobility mass spectrometry; ATD, arrival time distribution; MD, molecular dynamics; nano-ESI, nano-electrospray ionization; MAL

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Lipoprotein receptors and cholesterol in APP trafficking and proteolytic processing, implications for Alzheimer's disease

Keywords: AD، بیماری آلزایمر; LDLR, low-density lipoprotein receptor; LRP, LDLR-related protein; apoER2, apoE receptor 2; sorLA, sorting protein-related receptor containing LDLR class A repeats; AD, Alzheimer's disease; Aβ, amyloid-β peptide; APP, β-amyloid precursor protein; APLP1, a

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

(−)-Epigallocatechin-3-gallate prevents lipopolysaccharide-induced elevation of beta-amyloid generation and memory deficiency

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; Aβ, amyloid peptide; APP, β-amyloid precursor protein; EGCG, (−)-epigallocatechin-3-gallate; LPS, lipopolysaccharide; PS2, presenilin 2(−)-Epigallocatechin-3-gallate (EGCG); Lipopolysaccharide (LPS); Neuroinflammation; Alzheimer's

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Selective apoptosis induction in the hippocampal mossy fiber pathway by exposure to CT105, the C-terminal fragment of Alzheimer's amyloid precursor protein

Keywords: AD، بیماری آلزایمر; Aβ, β-amyloid protein; AD, Alzheimer's disease; APP, β-amyloid precursor protein; CLSM, confocal laser-scanning microscope; CT105, 105 amino acid carboxyl-terminal fragment of β-amyloid precursor protein; GluR2/3, AMPA-type glutamate receptor subunits 2 a

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Developmental expression and subcellular localization of glutaminyl cyclase in mouse brain

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; APP, amyloid precursor protein; BSA, bovine serum albumin; DAB, 3,3′-diaminobenzidine; GFAP, glial fibrillary acidic protein; PB, phosphate buffer; PBS, phosphate-buffered saline; QC, glutaminyl cyclaseAlzheimer's disease; Glutami

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Colocalization of dopamine receptor subtypes with dopamine and cAMP-regulated phosphoprotein (DARPP-32) in rat brain

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; cAMP, cyclic adenosine monophosphate; CB-1, cannabinoid receptor 1; CNS, central nervous system; DA, dopamine; DR, dopamine receptor; DARPP-32, dopamine and cAMP-regulated phosphoprotein; ERK, extracellular receptor kinases; GPCR,

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Mice deficient in dihydrolipoyl succinyl transferase show increased vulnerability to mitochondrial toxins

Keywords: AD، بیماری آلزایمر; DLST, dihydrolipoyl succinyl transferase; DLD, dihydrolipoamide dehydrogenase; OGDH, α-ketoglutarate dehydrogenase; KGDHC, α-ketoglutarate dehydrogenase complex; AD, Alzheimer's disease; HD, Huntington's disease; PD, Parkinson's disease; 8OH2dG, 8-hydroxy

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Transthyretin: More than meets the eye

Keywords: AD، بیماری آلزایمر; AD, Alzheimer's disease; ApoA-I, apolipoprotein A-I; Aβ, amyloid beta; APP, amyloid precursor protein; CNS, central nervous system; CSF, cerebrospinal fluid; DRG, dorsal root ganglion; FAP, familial amyloid polyneuropathy; GBS, Guillain–Barré syndrome; KO

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه