Keywords: AD، بیماری آلزایمر; α-syn, α-synuclein; Aβ, amyloid β; AD, Alzheimer disease; APP, amyloid precursor protein; a-SMase, acid sphingomyelinase; alk-SMase, Alkaline SMase; Cer, ceramide; CERT, ceramide transfer protein; CSF, cerebrospinal fluid; D609, tricyclodecan-9-yl-xanthog
مقالات ISI AD، بیماری آلزایمر (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: AD، بیماری آلزایمر; Aβ, amyloid-β peptide; AD, Alzheimer disease; APP, amyloid-β precursor protein; GSL, glycosphingolipid; CSF, cerebrospinal fluid; N2a, neuro2a; EGCase, endoglycoceramidaseExosome; Amyloid-β peptide; Alzheimer’s disease; Cynomolgus monkey; APP transgenic m
Keywords: AD، بیماری آلزایمر; AD, Alzheimer disease; MCI, mild cognitive impairment; MRI, magnetic resonance imaging; WML, white matter lesions; LPA, light-intensity physical activity; METs, multiples of the resting metabolic rate; MVPA, moderate-to-vigorous intensity physical activit
Keywords: AD، بیماری آلزایمر; AD, Alzheimer disease; eQTLs, expression quantitative trait loci; GGCRN, gene–gene co-regulation network; HPRD, Human Protein Reference Database; KEGG, Kyoto Encyclopedia of Genes and Genomes; PPI, protein–protein interaction; RWR, random walk with restar
Keywords: AD، بیماری آلزایمر; Adverse effects; Dementia; RehabilitationACSM, American College of Sports Medicine; AD, Alzheimer disease; CDR, Clinical Dementia Rating; CPET, cardiopulmonary exercise test; RPE, rating of perceived exertion
Keywords: AD، بیماری آلزایمر; AD, Alzheimer Disease; CHB, Chinese Han Beijing; CVD, cardiovascular disease; GWAS, genome-wide association study; MAF, minor allele frequency; OR, odds ratio; PD, Parkinson Disease; PCR, polymerase chain reaction; SNP, single nucleotide polymorphism.Card
Keywords: AD، بیماری آلزایمر; 2,4-D, 2,4-dichlorophenoxyacetic acid; 2,4,5-T, 2,4,5-trichlorophenoxyacetic acid; AD, Alzheimer disease; aOR, adjusted odds ratio; AhR, aryl hydrocarbon receptor; ALS, amyotrophic lateral sclerosis; BMI, body mass index; CI, confidence interval; CNS, cen
Keywords: AD، بیماری آلزایمر; AD, Alzheimer disease; MR, magnetic resonance; ROI, region of interest; SWI, susceptibility weighted imagingMagnetic resonance imaging; Susceptibility weighted imaging; Iron deposition; Aging; Alzheimer disease
Keywords: AD، بیماری آلزایمر; AD, Alzheimer disease; Aβ, β-amyloid; ROS, reactive oxygen species; GSH, glutathione; SOD, superoxide dismutase; GSH-Px, glutathione peroxidase; GR, glutathione reductase; MDA, malondialdehyde; MTT, 3-[4,5–dimethylthiazol–2–yl]-2,5-diphenyltetrazolium bro
Keywords: AD، بیماری آلزایمر; Anatomy; High field; Imaging; Molecular; MRI2D, Two-dimensional; 3D, Three-dimensional; 18F-FDG, 18F-fluorodeoxyglucose; AD, Alzheimer disease; AVM, Arteriovenous malformation; DBS, Deep brain stimulation; DG, Dentate gyrus; DTI, Diffusion tensor imaging;
Keywords: AD، بیماری آلزایمر; AVM, avermectin; AVMs, avermectins; α-Syn, alpha synuclein; NAC, non-amyloid-β-component;; AD, Alzheimer disease; NACP, non-amyloid-β-component precursor; PD, Parkinson's disease; MSA, multiple system atrophy; DLB, Dementia with Lewy bodies; UPP, ubiquiti
Keywords: AD، بیماری آلزایمر; AD, Alzheimer disease; CDR, Clinical Dementia Rating; CDR-SoB, Clinical Dementia Rating — Sum of Boxes; CDR-FUNC, Clinical Dementia Rating — Functional Subsum; MMSE, Mini-Mental State Examination; CAMCOG, Cambridge Cognitive Examination; FAQ, Pfeffer's Fu
Phage M13 for the treatment of Alzheimer and Parkinson disease
Keywords: AD، بیماری آلزایمر; AD, Alzheimer disease; PD, Parkinson disease; G3P, Gene 3 product; CED, Convection-enhanced-deliveryBacteriophage M13; Alzheimer disease; Parkinson disease
Association of interleukin-10 polymorphisms with risk factors of Alzheimer’s disease and other dementias (SADEM study)
Keywords: AD، بیماری آلزایمر; AD, Alzheimer disease; VaD, vascular dementia; AD/VaD, mixed dementia; IL-10, interleukin-10; SNP, single nucleotide polymorphism; MAF, proto-oncogeneAlzheimer's disease; Dementia; Genetic association; Haplotypes; Interleukin; Polymorphisms
Effects of chronic noise on mRNA and protein expression of CRF family molecules and its relationship with p-tau in the rat prefrontal cortex
Keywords: AD، بیماری آلزایمر; AD, Alzheimer disease; BSA, bovine serum albumin; CRF, corticotropin-releasing factor; CRFR1/2, Corticotropin-releasing factor receptor 1/2; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; HPA, hypothalamic-pituitary-adrenal; p-tau, phosphorylated tau; P
Characterization of F-spondin in Japanese flounder (Paralichthys olivaceus) and its role in the nervous system development of teleosts
Keywords: AD، بیماری آلزایمر; ECM, extracellular matrix; TSRs, thrombospondin repeats; APP, amyloid precursor protein; AD, Alzheimer disease; ISH, in situ hybridization; DIG, digoxigenin; SEM, standard error of the mean; ORF, open reading frame; TSR1, thrombospondin type 1 repeatJapan
A novel nicotinic mechanism underlies β-amyloid-induced neurotoxicity
Keywords: AD، بیماری آلزایمر; Aβ, amyloid-β; BFCN, basal forebrain cholinergic neurons; α7-nAChRs, α7-containing nicotinic acetylcholine receptors; AD, Alzheimer disease; Patch clamp;
Phenolic composition, antioxidant potential and in vitro inhibitory activity of leaves and acorns of Quercus suber on key enzymes relevant for hyperglycemia and Alzheimer's disease
Keywords: AD، بیماری آلزایمر; ABTS, 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid); DPPH, 2,2-diphenyl-1-picrylhydrazyl; DTNB, 5,5′-dithio-bis(2-nitrobenzoic) acid; Ach, acetylcholine; AChE, acetylcholinesterase; AChEI, AChE inhibitors; AD, Alzheimer disease; BuChE, butyrylch
The alpha secretase ADAM10: A metalloprotease with multiple functions in the brain
Keywords: AD، بیماری آلزایمر; ADAM, A Disintegrin And Metalloproteinase; BACE, β-site APP cleaving enzyme; APP, amyloid precursor protein; AD, Alzheimer disease; RIP, regulated intramembrane proteolysis; PC, prohormone convertase; CNS, central nervous system; UTR, untranslated region;
The endogenous α7 nicotinic acetylcholine receptor antagonist kynurenic acid modulates amyloid-β-induced inflammation in BV-2 microglial cells
Keywords: AD، بیماری آلزایمر; α7nAChR, α7 nicotinic acetylcholine receptor; Aβ, amyloid-β; AD, Alzheimer disease; DMSO, dimethyl sulfoxide; ELISA, enzyme-linked immunosorbent assay; FBS, fetal bovine serum; FACS, fluorescence-activated cell sorting; FDA, fluorescein diacetate; FITC, f
Hippocampus, caudate nucleus and entorhinal cortex volumetric MRI measurements in discrimination between Alzheimer’s disease, mild cognitive impairment, and normal aging
Keywords: AD، بیماری آلزایمر; MRI, magnetic resonance imaging; AD, Alzheimer disease; MCI, Mild Cognitive Impairment; PPV, positive predictive value; NPV, negative predictive value; DWI, diffusion weighted imaging; TE, echo time; TR, repetition time; NEX, number of excitations; p-valu
Abeta, oxidative stress in Alzheimer disease: Evidence based on proteomics studies
Keywords: AD، بیماری آلزایمر; 3NT, 3-Nitrotyrosine; HNE, 4-Hydroxynonenal; AD, Alzheimer disease; aMCI, amnestic mild cognitive impairment; APP, amyloid precursor protein; AICD, amyloid precursor protein intracellular domain; Aβ, amyloid-β; BACE1, beta-secretase 1; CTF, C-terminal fra
Discovery of a benzofuran derivative (MBPTA) as a novel ROCK inhibitor that protects against MPP+-induced oxidative stress and cell death in SH-SY5Y cells
Keywords: AD، بیماری آلزایمر; AD, Alzheimer disease; CM-H2DCFDA, 2′,7′-dichlorofluorescein diacetate; DAF-FM, 4-amino-5-methylamino-2′,7′-difluorofluorescein; FBS, fetal bovine serum; iNOS, inducible nitric oxide synthase; JC-1, 5,5′,6,6′-tetrachloro-1,1′,3,3′-tetraethylbenzimidazolyl
The 2013 SFRBM discovery award: Selected discoveries from the butterfield laboratory of oxidative stress and its sequela in brain in cognitive disorders exemplified by Alzheimer disease and chemotherapy induced cognitive impairment
Keywords: AD، بیماری آلزایمر; Aβ, amyloid β-peptide; AD, Alzheimer disease; ApoA1, apolipoprotein A1; BBB, blood brain barrier; CICI, chemotherapy-induced cognitive impairment; CSF, cerebral spinal fluid; Dox, doxorubicin; DS, Down syndrome; FAEE, ferulic acid ethyl ester; GCEE, gamma
Increased frequency of T cells expressing IL-10 in Alzheimer disease but not in late-onset depression patients
Keywords: AD، بیماری آلزایمر; Ab, beta amyloid peptide; AD, Alzheimer disease; BBB, blood–brain-barrier; COPD, chronic obstructive pulmonary disorder; GDS, Geriatric Depression Scale; IL-10, interleukin 10; LOD, late onset depression; MMSE, Mini-mental State Examination; PCR, polymera
Oxidative modification of lipoic acid by HNE in Alzheimer disease brain
Keywords: AD، بیماری آلزایمر; AD, Alzheimer disease; HNE, 4-hydroxy-2-trans nonenal; HNE-LA, HNE-bound lipoic acid; IPL, inferior parietal lobule; LA, lipoic acid; LADH, lipoamide dehydrogenase/dihydrolipoamide dehydrogenaseAlzheimer disease; Lipid peroxidation; 4-hydroxy-2-trans none
Exploration of deleterious single nucleotide polymorphisms in late-onset Alzheimer disease susceptibility genes
Keywords: AD، بیماری آلزایمر; AD, Alzheimer disease; nsSNP, non-synonymous single nucleotide polymorphism; LOAD, late-onset Alzheimer disease; GWAS, genome-wide association studies; CLU, encoding clusterin; PICALM, encoding phosphatidylinositol binding clathrin assembly protein; CR1,
A conceptual framework and ethics analysis for prevention trials of Alzheimer Disease
Keywords: AD، بیماری آلزایمر; Aβ, amyloid beta; AD, Alzheimer Disease; ADNI, Alzheimer's Disease Neuroimaging Initiative; API, Alzheimer Prevention Initiative; APOE, apolipoprotein E; BioM+, biomarker-positive; BioM−, biomarker-negative; CSF, cerebrospinal fluid; DIAN, Dominantly Inhe
Neurotoxins released from interferon-gamma-stimulated human astrocytes
Keywords: AD، بیماری آلزایمر; AD, Alzheimer disease; cDNA, complementary DNA; CM, conditioned medium; COX, cyclooxygenase; DMEM, Dulbecco’s-modified Eagle’s medium; DPI, diphenylene iodonium; EDTA, ethylene diamine tetra-acetic acid; EGTA, ethylene glycol tetraacetic acid; FBS, fetal
Thalamic cholinergic innervation is spared in Alzheimer disease compared to parkinsonian disorders
Keywords: AD، بیماری آلزایمر; PPN, pedunculopontine nucleus; LDTC, laterodorsal tegmental complex; PET, positron emission tomography; [11C]PMP, AChE [11C]-methyl-4-piperidinyl propionate; AD, Alzheimer disease; PD, Parkinson disease; PDD, Parkinson disease with dementia; DLB, dementia
Erlin-2 is associated with active γ-secretase in brain and affects amyloid β-peptide production
Keywords: AD، بیماری آلزایمر; Aβ, amyloid β-peptide; ACN, acetonitrile; AD, Alzheimer disease; AICD, APP intracellular domain; APP, Aβ precursor protein; FA, formic acid; GCB, γ-secretase inhibitor coupled to biotin via a cleavable linker; GSAPs, γ-secretase associated proteins; IP, i
New perspectives in melatonin uses
Keywords: AD، بیماری آلزایمر; AANAT, N-acetyltransferase; AD, Alzheimer disease; AFMK, N1-acetyl-N2-formyl-5-methoxykynuramine; AMK, N1-acetyl-5-methoxykynuramine; CAT, catalase; CNS, central nervous system; ETC, electron transport chain; GI, gastrointestinal; GPCR, 7-transmembrane G-
MAP1B 1–126 interacts with tubulin isoforms and induces neurite outgrowth and neuronal death of cultured cortical neurons
Keywords: AD، بیماری آلزایمر; Aß, ß-amyloid; AD, Alzheimer disease; DIV, days in vitro; GST, glutathione-S-transferase; HC, heavy chain; LC, light chain; MAP1B, microtubule associated protein 1B; NFT, neurofibrillary tangleMAP1B; Microtubule binding; Neuronal death; Caspase
Photobiomodulation by low-power laser irradiation attenuates Aβ-induced cell apoptosis through the Akt/GSK3β/β-catenin pathway
Keywords: AD، بیماری آلزایمر; Aβ, amyloid-β-peptide; AD, Alzheimer disease; LPLI, low-power laser irradiation; TCF, T-cell factor; LEF, lymphocyte enhancer factor; YAP, Yes-associated protein; GSK3β, glycogen synthase kinase 3β; NFTs, neurofibrillary tangles; YFP, yellow fluorescence
An open system for automatic home-cage behavioral analysis and its application to male and female mouse models of Huntington's disease
Keywords: AD، بیماری آلزایمر; AD, Alzheimer disease; PD, Parkinson's disease; HD, Huntington's disease; WT, wild-typeMouse behavior; Home cage behavior; Video-based automated behavior phenotyping; Huntington's disease; R6/2 transgenic mouse
Heme oxygenase-1 posttranslational modifications in the brain of subjects with Alzheimer disease and mild cognitive impairment
Keywords: AD، بیماری آلزایمر; 3-NT, 3-nitrotyrosine; AD, Alzheimer disease; HNE, 4-hydroxy-2-nonenal; HO, heme oxygenase; MCI, mild cognitive impairment; PC, protein carbonyls; pSer, phosphoserine; pThr, phosphothreonine; pTyr, phosphotyrosineAlzheimer disease; Heme oxygenase; Mild co
Identification of two novel synaptic γ-secretase associated proteins that affect amyloid β-peptide levels without altering Notch processing
Keywords: AD، بیماری آلزایمر; Aβ, amyloid β-peptide; AD, Alzheimer disease; APP, amyloid precursor protein; CFL1, cofilin-1; CTF, carboxyterminal fragment; GCB, γ-secretase inhibitor with a cleavable biotin moiety; GSAP, γ-secretase associated protein; HEK, human embryonic kidney; LC-
Neurotransmitter receptors and cognitive dysfunction in Alzheimer's disease and Parkinson's disease
Keywords: AD، بیماری آلزایمر; AD, Alzheimer disease; PD, Parkinson's disease; NMDA receptors, N-methyl-d-aspartate receptors; GPCRs, G protein-coupled receptors; PKA, protein kinase A; PLC, phospholipase C; cAMP, cyclic advenosine monophosphato; CREB, cAMP response element binding pro
Physical exercise as a possible strategy for brain protection: Evidence from mitochondrial-mediated mechanisms
Keywords: AD، بیماری آلزایمر; AIF, apoptosis inducing factor; ATP, adenosine triphosphate; AD, Alzheimer disease; BDNF, brain-derived neurotrophic factor; Ca2+, calcium; CAT, catalase; Cu/Zn-SOD, copper/zinc superoxide dismutase; Drp1, dynamin-related protein 1; ETC, electron transpor
Increased short latency afferent inhibition after anodal transcranial direct current stimulation
Keywords: AD، بیماری آلزایمر; tDCS, transcranial direct current stimulation; AD, Alzheimer disease; SLAI, short latency afferent inhibition; MEP, motor evoked potential; TMS, transcranial magnetic stimulation; FDI, first dorsal interosseous; RMT, resting motor threshold; MSO, maximum
Novel demonstration of conformationally modified tau in sporadic inclusion-body myositis muscle fibers
Keywords: AD، بیماری آلزایمر; AD, Alzheimer disease; PHFs, paired-helical filaments; s-IBM, sporadic inclusion-body myositisSporadic inclusion-body myositis; Conformationally modified tau; Alz50; TG3; MC1; Paired-helical filaments; Alzheimer disease
Protective effects of 17β estradiol on altered age related neuronal parameters in female rat brain
Keywords: AD، بیماری آلزایمر; AD, Alzheimer disease; E2, 17β-estradiol; GST, glutathione-S-transferases; ROS, reactive oxygen species; SOD, superoxide dismutaseAntioxidant enzymes; Brain aging; Estradiol; Membrane linked ATPases; Neurolipofuscin; Oxidative stress
Mechanism of inhibition of PP2A activity and abnormal hyperphosphorylation of tau by I2PP2A/SET
Keywords: AD، بیماری آلزایمر; AD, Alzheimer disease; PP2A, protein phosphatase-2A; MEK1/2, MAP kinase kinase; ERK 1/2, extracellular regulated kinase; PHAP1, putative histocompatibility leukocyte antigen class II associated protein-1Alzheimer disease; Asparaginyl endopeptidase; Ischem
The ALS/PDC syndrome of Guam: Potential biomarkers for an enigmatic disorder
Keywords: AD، بیماری آلزایمر; AD, Alzheimer disease; ALS/PDC, amyotrophic lateral sclerosis/parkinsonism dementia complex; BMAA, beta methyl amino alanine; CYP2D6, cytochrome P450 2D6; FTDP-17, frontotemporal dementia and parkinsonism linked to chromosome 17; LRPE, linear retinal pigm
Calmodulin regulates the non-amyloidogenic metabolism of amyloid precursor protein in platelets
Keywords: AD، بیماری آلزایمر; APP, amyloid precursor protein; Aβ, amyloid β peptide; AD, Alzheimer disease; mAb, monoclonal antibodyAmyloid precursor protein; Human platelets; Proteolysis; Calmodulin
β-Amyloid peptide increases levels of iron content and oxidative stress in human cell and Caenorhabditis elegans models of Alzheimer disease
Keywords: AD، بیماری آلزایمر; Aβ, β-amyloid peptide; AD, Alzheimer disease; ANOVA, analysis of variance; APP, β-amyloid precursor protein; APPsw, β-amyloid precursor protein Swedish mutation; DAF-2DA, 4,5-diaminofluorescein diacetate; DCFH-DA, 2′,7′-dichlorodihydrofluorescein diacetat
ACS84, a novel hydrogen sulfide-releasing compound, protects against amyloid β-induced cell cytotoxicity
Keywords: AD، بیماری آلزایمر; H2S, hydrogen sulfide; Aβ, amyloid beta; CBS, cystathionine β-synthase; CSE, cystathionine γ-lyase; AD, Alzheimer disease; CSF, cerebrospinal fluid; NSAIDs, nonsteroidal anti-inflammatory drugs; DMEM, Dulbecco's modified Eagle's medium; COX-2, cyclooxygen
Oxidatively generated DNA damage after Cu(II) catalysis of dopamine and related catecholamine neurotransmitters and neurotoxins: Role of reactive oxygen species
Keywords: AD، بیماری آلزایمر; AD, Alzheimer disease; PD, Parkinson disease; ROS, reactive oxygen species; nDNA, nuclear DNA; mtDNA, mitochondrial DNA; ST-DNA, salmon testis DNA; SOD, superoxide dismutase; TBP, N-tert-butyl-α-phenylnitrone; TMP, 2,2,6,6-tetramethyl-4-piperidone; PEI, p
Development of Alzheimer-disease neuroimaging-biomarkers using mouse models with amyloid-precursor protein-transgene expression
Keywords: AD، بیماری آلزایمر; AD, Alzheimer disease; APP, amyloid precursor protein; CSF, cerebrospinal fluid; FDG, [F-18]fluorodeoxyglucose; MCI, mild cognitive impairment; MRI, magnetic resonance imaging; MRS, magnetic resonance spectroscopy; NAA, N-acetylaspartate; PET, positron em
β-Amyloid impairs axonal BDNF retrograde trafficking
Keywords: AD، بیماری آلزایمر; AD, Alzheimer disease; Aβ, β-amyloid; APP, amyloid precursor protein; BDNF, brain-derived neurotrophic factor; CNS, central nervous system; LTP, long-term potentiation; PI3K, phosphoinositide-3-kinase; PS1, presenilin-1; Rab7, Ras-related GTP-binding prot