Keywords: عضله صاف راه هوایی; Airway inflammation; Airway remodeling; Anti-muscarinic drug; Cholinergic regulation; Non-neuronal ACh; ACh; acetylcholine; ASM; airway smooth muscle; cAMP; cyclic adenosine monophosphate; ChAT; choline acetyltransferase; CHT1; high-affinity choline trans
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Keywords: عضله صاف راه هوایی; COPD; chronic obstructive pulmonary disease; O3; ozone; BUD; budesonide; BALF; bronchoalveolar lavage fluid; MMP; matrix metalloproteinase; HIF-1α; hypoxia-inducible factor-1α; VEGF; vascular endothelial growth factor; α-SMA; α-smooth muscle actin; GS
Keywords: عضله صاف راه هوایی; ANOVA; Analysis of variance; ASM; Airway smooth muscle; BALF; Bronchoalveolar lavage fluid; cDNA; Complementary DNA; COL1α1; Collagen, type I, alpha 1; CON; Conventional chronic model/protocol; H&E; Hematoxylin and eosin; IL; Interleukin; MMP-9; Matrix m
Keywords: عضله صاف راه هوایی; ACQ; asthma control questionnaire; AHR; airway hyperresponsiveness; Anti-IL5; anti-interleukin 5; AQLQ; asthma quality of life questionnaire; ASM; airway smooth muscle; BAL; bronchoalveolar lavage; BT; Bronchial Thermoplasty; ECM; extracellular matrix; ED
Keywords: عضله صاف راه هوایی; XHE-III-74; Deuterated compounds; Asthma; GABAA receptor; Airway hyperresponsiveness; Airway smooth muscle;
Keywords: عضله صاف راه هوایی; Elastography; Finite element method; Image registration; Airway smooth muscle; Deep inspiration; Bronchodilation;
Keywords: عضله صاف راه هوایی; AEC; airway epithelial cell; AHR; airway hyperresponsiveness; AM; alveolar macrophage; APC; antigen presenting cell; ASM; airway smooth muscle; BAL; bronchoalveolar lavage; CCR; C-C chemokine receptor; CCL; C-C motif ligand; DAMP; damage-associated molecu
Keywords: عضله صاف راه هوایی; ACOS; asthma and chronic obstructive pulmonary disease overlap syndrome; ACQ; Asthma Control Questionnaire; AHR; airway hyperresponsiveness; ASM; airway smooth muscle; BAL; bronchoalveolar lavage; BHR; bronchial hyperresponsiveness; CLCA1; chloride channe
Keywords: عضله صاف راه هوایی; airway inflammation; asthma; cytokines; AHR; airway hyper-responsiveness; ASM; airway smooth muscle; DC; dendritic cell; hMab; human monoclonal antibody; TJ; tight junction; TSLP; thymic stromal lymphopoietin; TSLPR; thymic stromal lymphopoietin receptor;
Keywords: عضله صاف راه هوایی; asthma; COPD; metabolism; oxidative stress; remodeling; ASM; airway smooth muscle; ATP; adenosine triphosphate; CS; cigarette smoke; DAMP; damage-associated molecular pattern; Drp1; dynamin-related protein 1; ER; endoplasmic reticulum; Fis1; fission 1; Mf
Keywords: عضله صاف راه هوایی; Refractory asthma; asthma control; airway smooth muscle; airway remodeling; epithelium neuroendocrine cells; mucosal nerves; bronchial epithelium; ACT; Asthma Control Test; AQLQ; Asthma Quality of Life Questionnaire; ASM; Airway smooth muscle; BT; Bronchi
Keywords: عضله صاف راه هوایی; Airway epithelium; airway smooth muscle; cytokines; eosinophil; inflammation; inflammatory mediators; lymphocyte; mast cell
Keywords: عضله صاف راه هوایی; Airway smooth muscle; Length adaptation; Bronchi; Hyperresponsiveness;
Keywords: عضله صاف راه هوایی; CA; citric acid; ASM; airway smooth muscle; BAL; bronchoalveolar lavage; BALF; BAL fluid; PAS; periodic acid-Schiff; TGF; transforming growth factor; NACC; non-asthmatic chronic cough; Chronic cough; Airway remodeling; Cough reflex hypersensitivity; Airwa
Keywords: عضله صاف راه هوایی; asthma; COPD; pulmonary fibrosis; pulmonary hypertension; ADDS; antibody-dependent degranulatory synapse; ASM; airway smooth muscle; β2-AR; β2-adrenergic receptor; Ca2+; calcium ion; CADM1; cell adhesion molecule 1; CD; cluster of differentiation; CPA3;
Keywords: عضله صاف راه هوایی; ARDS; acute respiratory distress syndrome; AHR; airway hyperresponsiveness; ASM; airway smooth muscle; BAL; bronchoalveolar lavage; CPA; carboxypeptidase A; CADM1; cell adhesion molecule 1; COPD; chronic obstructive pulmonary disease; NADPH; dihydronicoti
Keywords: عضله صاف راه هوایی; ASM; airway smooth muscle; AHR; airway hyperresponsiveness; β2AR; beta 2 adrenergic receptor; BTR; bitter taste receptor; CysLT1R; cysteinyl leukotriene receptor 1; CaSR; calcium sensing receptor; EP; prostanoid EP receptor; GPCR; G protein-coupled recep
Keywords: عضله صاف راه هوایی; ADAM; A Disintegrin And Metalloprotease Domain; AHR; airway hyperreponsiveness; Ang; angiopoietin; ASM; airway smooth muscle; BALf; bronchoalveolar lavage fluid; bFGF; basic fibroblast growth factor; BM; basement membrane; Col; collagen; CTGF; connective
Keywords: عضله صاف راه هوایی; AIR; Asthma Intervention Research; AQLQ; Asthma Quality of Life Questionnaire; ASM; airway smooth muscle; FDA; US Food and Drug Administration; ICS; inhaled corticosteroid; PPS; posterior probability of success; QOL; quality of life;
Keywords: عضله صاف راه هوایی; Complement mediated injury; Asthma; Anaphylatoxins; AHR; airway hyperresponsiveness; BAL; bronchoalveolar lavage; ASM; airway smooth muscle; MAC; membrane attack complex; Treg; regulatory T cells;
Keywords: عضله صاف راه هوایی; β2-AR; β2-adrenoreceptor; ASM; airway smooth muscle; BI; Bliss independence; COPD; chronic obstructive pulmonary disease; CRC; concentration-response curve; E; effect; EFS; electrical field stimulation; ECn; effective concentration for n% of maximal eff
Keywords: عضله صاف راه هوایی; Bronchial thermoplasty; Airway smooth muscle; Severe asthma;
Keywords: عضله صاف راه هوایی; Asthma; Airway smooth muscle; Contraction; Airway mechanics; Mechanotransduction;
Keywords: عضله صاف راه هوایی; Airway smooth muscle; Animal model; Chronic lung diseases; Montelukast; Salbutamol; COPD; chronic obstructive pulmonary diseases; BSMC; bronchial smooth muscle cells;
SIRT7 regulates the TGF-β1-induced proliferation and migration of mouse airway smooth muscle cells by modulating the expression of TGF-β receptor I
Keywords: عضله صاف راه هوایی; ASM; airway smooth muscle; CCK-8; Cell Counting Kit-8; FBS; fetal bovine serum; RT-qPCR; real-time quantitative polymerase chain reaction; SIRT7; sirtuin 7; TβRI; TGF-β receptor I; TGF-β1; transforming growth factor-beta 1; Airway smooth muscle cells;
Selective inhibition of histamine-evoked Ca2+ signals by compartmentalized cAMP in human bronchial airway smooth muscle cells
Keywords: عضله صاف راه هوایی; AC; adenylyl cyclase; 2-APB; 2-aminoethoxyphenylborane; ASM; airway smooth muscle; cAMP; 3',5'-cyclic AMP; COPD; chronic obstructive pulmonary disease; [Ca2+]i; intracellular free Ca2+ concentration; DMSO; dimethyl sulfoxide; EC50 (IC50); half-maximally e
Selectively targeting prostanoid E (EP) receptor-mediated cell signalling pathways: Implications for lung health and disease
Keywords: عضله صاف راه هوایی; ASM; airway smooth muscle; BAL; bronchoalveolar; CHO; Chinese hamster ovary; COX; cyclooxygenase; EP; prostanoid E; ERK; extracellular signal-regulated kinase; GPCR; G protein-coupled receptors; GSK-3; glucogen synthase kinase-3; HMLC; human lung mast cel
Chronic IL-33 expression predisposes to virus-induced asthma exacerbations by increasing type 2 inflammation and dampening antiviral immunity
Keywords: عضله صاف راه هوایی; IL-33; rhinovirus; asthma; exacerbation; antiviral; AEC; Airway epithelial cell; ASM; Airway smooth muscle; BALF; Bronchoalveolar lavage fluid; CRE; Cockroach extract; FITC; Fluorescein isothiocyanate; HMGB1; High-mobility group box 1; ILC2; Type 2 innate
Testosterone induces hyporesponsiveness by interfering with IP3 receptors in guinea pig airway smooth muscle
Keywords: عضله صاف راه هوایی; Airway smooth muscle; Testosterone; Airway responsiveness; Intracellular Ca2+; IP3 receptor isoforms;
Inflammatory mediators mediate airway smooth muscle contraction through a G protein-coupled receptor-transmembrane protein 16A-voltage-dependent Ca2+ channel axis and contribute to bronchial hyperresponsiveness in asthma
Keywords: عضله صاف راه هوایی; Airway smooth muscle; asthma; hypersensitivity; inflammatory mediator; TMEM16A; 5-HT; 5-Hydroxytryptamin; Ai38D; Cre-dependent GCaMP3 reporter mouse; ASM; Airway smooth muscle; ASMC; Airway smooth muscle cell; ClCa; Ca2+-activated Clâ; CTR; Control; GCa
Orosomucoid-like 3 (ORMDL3) upregulates airway smooth muscle proliferation, contraction, and Ca2+ oscillations in asthma
Keywords: عضله صاف راه هوایی; ORMDL3; asthma; airway smooth muscle; sarcoplasmic reticulum Ca2+ transport ATPase 2b; airway hyperresponsiveness; AHR; Airway hyperresponsiveness; ASM; Airway smooth muscle; [Ca2+]i; Intracellular Ca2+; CPA; Cyclopiazonic acid; DMEM; Dulbecco modified Ea
S100A8 protein attenuates airway hyperresponsiveness by suppressing the contraction of airway smooth muscle
Keywords: عضله صاف راه هوایی; S100A8; Asthma; Airway hyperresponsiveness; Airway smooth muscle; Contraction;
Doxofylline does not increase formoterol-induced cAMP nor MKP-1 expression in ASM cells resulting in lack of anti-inflammatory effect
Keywords: عضله صاف راه هوایی; Theophylline; Cilomilast; Interleukin 8; COPD; Asthma; Chemokine; ASM; airway smooth muscle; MAPK; mitogen-activated protein kinase; MKP-1; MAPK phosphatase 1; PDE; phosphodiesterase; PP2A; protein phosphatase 2A; TNF; tumour necrosis factor;
Leukotriene receptor antagonist attenuated airway inflammation and hyperresponsiveness in a double-stranded RNA-induced asthma exacerbation model
Keywords: عضله صاف راه هوایی; Asthma; Cysteinyl leukotrienes; Double-stranded RNA; Leukotriene receptor antagonist; Virus; Ach; acetylcholine; AHR; airway hyperresponsiveness; ASM; airway smooth muscle; BAL; bronchoalveolar lavage; BALF; bronchoalveolar lavage fluid; CCL; Chemokine (C
An in vitro study examining the duration between deep inspirations on the rate of renarrowing
Keywords: عضله صاف راه هوایی; Airway smooth muscle; Oscillating strain; Breathing maneuvers; Deep inspiration; Asthma;
Responsiveness to bronchodilator procaterol in COPD as assessed by forced oscillation technique
Keywords: عضله صاف راه هوایی; Airway; Airway smooth muscle; Forced oscillation technique; Impedance; Bronchodilator; Procaterol;
CD38 in the pathogenesis of allergic airway disease: Potential therapeutic targets
Keywords: عضله صاف راه هوایی; Airway smooth muscle; Asthma; CD38; MicroRNAs; Calcium regulation;
Development of therapeutic antibodies to G protein-coupled receptors and ion channels: Opportunities, challenges and their therapeutic potential in respiratory diseases
Keywords: عضله صاف راه هوایی; ASM; airway smooth muscle; CFTR; cystic fibrosis transmembrane conductance regulator; COPD; chronic obstructive pulmonary disease; FPR; formyl peptide receptor; GPCR; G protein-coupled receptor; TRP; transient receptor potential; G protein-coupled recepto
Prostaglandin E2 induces expression of MAPK phosphatase 1 (MKP-1) in airway smooth muscle cells
Keywords: عضله صاف راه هوایی; Prostaglandins; Cell signalling; CREB; MKP-1; Airway smooth muscle; Inflammation;
Interaction between corticosteroids and muscarinic antagonists in human airways
Keywords: عضله صاف راه هوایی; Airway smooth muscle; Asthma; ICS; LAMA; Drug interactionANOVA, analysis of variance; ASM, airway smooth muscle; BHR, bronchial hyperresponsiveness; BI, Bliss Independence; cAMP, cyclic adenosine monophosphate; COPD, chronic obstructive pulmonary disease;
Pulmonary, gastrointestinal and urogenital pharmacologyNa+ permeates through L-type Ca2+ channel in bovine airway smooth muscle
Keywords: عضله صاف راه هوایی; L-type Ca2+ channels; Subunit CaV1.2; Na+ permeability; Airway smooth muscle; Sarcoplasmic reticulum Ca2+ release; Contraction;
Brain natriuretic peptide modulates calcium homeostasis and epidermal growth factor receptor gene signalling in asthmatic airways smooth muscle cells
Keywords: عضله صاف راه هوایی; BNP; Contraction; Airway smooth muscle; EGFR signalling; α-Smooth muscle actin;
CTNNA3 and SEMA3D: Promising loci for asthma exacerbation identified through multiple genome-wide association studies
Keywords: عضله صاف راه هوایی; Asthma; exacerbation; genome-wide association study; expression quantitative trait locus; CTNNA3; SEMA3D; biobank; childhood asthma; ABRIDGE; Asthma BioRepository for Integrative Genomic Exploration; ASM; Airway smooth muscle; BioVU; Biobank of Vanderbilt
γ-Tocotrienol reduces human airway smooth muscle cell proliferation and migration
Keywords: عضله صاف راه هوایی; Vitamin E; γ-Tocotrienol; Airway smooth muscle; Asthma;
Expression of CysLT2 receptors in asthma lung, and their possible role in bronchoconstriction
Keywords: عضله صاف راه هوایی; Airway smooth muscle; Anti-asthma drugs; CysLT receptors; Cysteinyl leukotrienes; Leukotriene receptor antagonistCysLT, cysteinyl leukotriene; ICS, inhaled corticosteroids; LABA, long-acting β2 receptor agonist
Pharmacological characterization of the interaction between the dual phosphodiesterase (PDE) 3/4 inhibitor RPL554 and glycopyrronium on human isolated bronchi and small airways
Keywords: عضله صاف راه هوایی; RPL554; Glycopyrronium; Synergistic interaction; Relaxant response; Human isolated bronchi; Small airways; Airway smooth muscle; Asthma; COPD; β2-AR; β2-adrenoreceptor; ASM; airway smooth muscle; BI; Bliss independence; COPD; chronic obstructive pulmona
Obesity and asthma: beyond TH2 inflammation
Keywords: عضله صاف راه هوایی; AHR; airway hyperreactivity; AKT; RAC-alpha serine/threonine-protein kinase; AMPK; adenosine monophosphate-activated kinase; ARPF; airway-related pre-ganglionic fibers; ASM; airway smooth muscle; BAL; bronchoalveolar lavage; BMI; body mass index; BTSM; bo
Vitamin D for the treatment of respiratory diseases: Is it the end or just the beginning?
Keywords: عضله صاف راه هوایی; 1,25(OH)2D; 1,25-dihydroxyvitamin D3; 25(OH)D; 25-hydroxyvitamin D3; AFRS; allergic fungal rhinosinusitis; APC; antigen presenting cell; AR; allergic rhinitis; ASM; airway smooth muscle; ATAQ; asthma therapy assessment questionnaire; CCL; chemokine (CC mo
Associate editor: Ikuko KimuraResearch and development of bronchodilators for asthma and COPD with a focus on G protein/KCa channel linkage and β2-adrenergic intrinsic efficacy
Keywords: عضله صاف راه هوایی; Airway smooth muscle; β2-adrenergic receptor agonists; Muscarinic receptor antagonists; Ca2+-activated K+ channels; Voltage-dependent Ca2+ channels; Allosteric modulators of G protein-coupled receptors;
ReviewSophora flavescens Ait.: Traditional usage, phytochemistry and pharmacology of an important traditional Chinese medicine
Keywords: عضله صاف راه هوایی; 5-HT; 5-hydroxytryptamine; 5R-DHT; 5R-dihydrotestosterone; Ach; Acetylcholine; AGE; Advanced glycation end product; AHR; Airway hyperreactivity; ALP; Alkaline phosphatase; ANP; Atrial natriuretic peptide; ASM; Airway smooth muscle; cGMP-PDE5; Cyclic guano