دانلود مقالات ISI درباره آکت + ترجمه فارسی

Combination of galectin inhibitor GCS-100 and BH3 mimetics eliminates both p53 wild type and p53 null AML cells

Keywords: آکت; LGALS3; Galectin 3; LGALS1; Galectin 1; AML; Acute myeloid leukemia; qRT-PCR; Real-time PCR; AKT; Protein kinase B; ERK; Extracellular receptor kinase; BCL2; B cell lymphoma 2; BCL-XL; B cell lymphoma 2 Like 1; MCL-1; Myeloid cell leukemia 1; Ph +;  Phi

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

A hydrogen peroxide safety valve: The reversible phosphorylation of catalase from the freeze-tolerant North American wood frog, Rana sylvatica

Keywords: آکت; Akt; Protein kinase B; AMPK; Adenosine monophosphate-activated protein kinase; cAMP; Cyclic adenosine monophosphate; CAMK; Calmodulin dependent kinase; Cdc2; Cyclin dependent kinase 1; Cdk5; Cyclin dependent kinase 5; cGMP; Cyclic guanidine monophosphate;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Reduced AKT phosphorylation contributes to endoplasmic reticulum stress-mediated hippocampal neuronal apoptosis in rat recurrent febrile seizure

Keywords: آکت; Febrile seizure; ERS; TRIB3; AKT; Apoptosis

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Research reportPTP4A3 is a target for inhibition of cell proliferatin, migration and invasion through Akt/mTOR signaling pathway in glioblastoma under the regulation of miR-137

Keywords: آکت; miR-137; PTP4A3; Akt; mTOR; Glioblastoma multiforme;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Early effects of Aβ1-42 oligomers injection in mice: Involvement of PI3K/Akt/GSK3 and MAPK/ERK1/2 pathways

Keywords: آکت; Beta-amyloid; Cognitive impairment; Oxidative stress; Akt; ERK1/2; GSK3

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Apigenin and naringenin ameliorate PKCβII-associated endothelial dysfunction via regulating ROS/caspase-3 and NO pathway in endothelial cells exposed to high glucose

Keywords: آکت; PKCβII; protein kinase C βII; ROS; reactive oxygen species; HUVECs; human umbilical vein endothelial cells; HAECs; human aortic endothelial cells; NF-κB; nuclear factor-κB; NO; nitric oxide; DMSO; dimethyl sulfoxide; ACh; acetylcholine; PE; phenylephr

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

MED27 promotes melanoma growth by targeting AKT/MAPK and NF-κB/iNOS signaling pathways

Keywords: آکت; MED27; Melanoma; AKT; MAPK; NF-κB; iNOS;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Human umbilical cord blood derived mesenchymal stem cells improve cardiac function in cTnTR141W transgenic mouse of dilated cardiomyopathy

Keywords: آکت; Umbilical cord blood mesenchymal stem cells; Dilated cardiomyopathy; Akt; Paracrine effects;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Effect of dehydroepiandrosterone (DHEA) on Akt and protein kinase C zeta (PKCζ) phosphorylation in different tissues of C57BL6, insulin receptor substrate (IRS)1−/−, and IRS2−/− male mice fed a high-fat diet

Keywords: آکت; Dehydroepiandrosterone; Liver; Akt; IRS1; IRS2;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Carbohydrate-based peptidomimetics targeting neuropilin-1: Synthesis, molecular docking study and in vitro biological activities

Keywords: آکت; MRI; magnetic resonance imaging; AKT; serine/threonine protein kinase; ERK1/2; extracellular signal-regulated protein kinases 1 and 2; Neuropilin-1; VEGF; Carbohydrate scaffolds; Peptidomimetics; Molecular modeling;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Preservation of cell-survival mechanisms by the presenilin-1 K239N mutation may cause its milder clinical phenotype

Keywords: آکت; Presenilin 1 mutation; Amyloid-β; Oxidative stress; Apoptosis; MAP kinase signaling; Akt;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Original ArticleMelanocytes/MelanomaMIG6 Is MEK Regulated and Affects EGF-Induced Migration in Mutant NRAS Melanoma

Keywords: آکت; AKT; v-akt murine thymoma viral oncogene homolog; BRAF; v-raf murine sarcoma viral oncogene homolog B1; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; ERBB; v-erb-b2 erythroblastic leukemia viral oncogene homolog; ERK; extracellular

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Collagen XVII Shedding Suppresses Re-Epithelialization by Directing Keratinocyte Migration and Dampening mTOR Signaling

Keywords: آکت; ADAMs; a disintegrin and metalloproteinases; Akt; acutely transforming retrovirus AKT8 in rodent T-cell lymphoma; ECM; extracellular matrix; HD; hemidesmosome; mTOR; mechanistic target of rapamycin; PI3K; phosphoinositide 3-kinase;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Original ArticleKeratinocytes/EpidermisConstitutive Autophagy and Nucleophagy during Epidermal Differentiation

Keywords: آکت; AKT; acutely transforming retrovirus AKT8 in rodent T-cell lymphoma; HP1α; heterochromatin protein 1α; LMNA; lamin A; LMNB1; lamin B1;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

LRG1 mRNA expression in breast cancer associates with PIK3CA genotype and with aromatase inhibitor therapy outcome

Keywords: آکت; PIK3CA mutations; Breast cancer; First line aromatase inhibitors therapy; LRG1; AI; aromatase inhibitors; AKT; also known as Protein kinase B (PKB); BC; breast cancer; ER; estrogen receptor; FAM81B; family with sequence similarity, 81 member B; HER2; huma

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Phosphorylation of MITF by AKT affects its downstream targets and causes TP53-dependent cell senescence

Keywords: آکت; MITF; AKT; Phosphorylation; TP53; Senescence;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Improvement of mTORC1-driven overproduction of apoB-containing triacylglyceride-rich lipoproteins by short-chain fatty acids, 4-phenylbutyric acid and (R)-α-lipoic acid, in human hepatocellular carcinoma cells

Keywords: آکت; ACC; acetyl-CoA carboxylase; Akt; protein kinase B; AMPK; AMP-activated protein kinase; apoB; apolipoprotein B; apoE; apolipoprotein E; CPT1α; carnitine palmitoyltransferase 1α; DGAT1; diacylglycerol O-acyltransferase 1; DGAT2; diacylglycerol O-acyltran

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Protective effects of DJ-1 medicated Akt phosphorylation on mitochondrial function are promoted by Da-Bu-Yin-Wan in 1-methyl-4-phenylpyridinium-treated human neuroblastoma SH-SY5Y cells

Keywords: آکت; Parkinson's disease; Mitochondrial dysfunction; DJ-1; Akt; Phosphorylation; Da-Bu-Yin-Wan

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

A novel dual GLP-1 and GIP receptor agonist is neuroprotective in the MPTP mouse model of Parkinson′s disease by increasing expression of BNDF

Keywords: آکت; Insulin; Apoptosis; Incretin; Growth factor; AKT; Neuron

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Genistein alleviates lead-induced neurotoxicity in vitro and in vivo: Involvement of multiple signaling pathways

Keywords: آکت; Akt; protein kinase B; BLL; blood lead level; Bax; Bcl-2-associated X protein; Bcl-2; B-cell leukemia/lymphoma-2; CAT; catalase; GEN; genistein; ERK; extracellular signal-regulated kinases; GCI; global cerebral ischemia; Pb; lead; MAPK; mitogen-activated

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

VIP and PACAP analogs regulate therapeutic targets in high-risk neuroblastoma cells

Keywords: آکت; MYCN; ALK; AKT; PKA; Invasion; Differentiation;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Chinese herbal medicine Fuzheng Kang-Ai decoction sensitized the effect of gefitinib on inhibition of human lung cancer cells through inactivating PI3-K/Akt -mediated suppressing MUC1 expression

Keywords: آکت; FZKA decoction; Gefitinib; NSCLC cells; Akt; P65; MUC1;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Disruption of Akt signaling decreases dopamine sensitivity in modulation of inhibitory synaptic transmission in rat prefrontal cortex

Keywords: آکت; Dopamine; Dopamine receptors; Inhibitory synaptic transmission; Akt; Prefrontal cortex; Schizophrenia;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Neuronal Ca2+ sensor-1 contributes to stress tolerance in cardiomyocytes via activation of mitochondrial detoxification pathways

Keywords: آکت; Akt; protein kinase B; AMPK; AMP-activated protein kinase; ATP; adenosine triphosphate; CaMKII; Ca2+/calmodulin-dependent protein kinase II; FCCP; carbonyl cyanide-p-trifluoromethoxyphenylhydrazone; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; GSK3β;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

MiR-18b suppresses high-glucose-induced proliferation in HRECs by targeting IGF-1/IGF1R signaling pathways

Keywords: آکت; DR; diabetic retinopathy; PDR; proliferative diabetic retinopathy; HRECs; human retinal endothelial cells; REC; retinal microvascular endothelial cell; VEGF; vascular endothelial growth factor; IGF-1; insulin growth factor-1; IGF1R; insulin growth factor-

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

The histamine H4-receptor and the central and peripheral nervous system: A critical analysis of the literature

Keywords: آکت; Histamine H4 receptor; Nervous system; Neuron; Microglia; Antibody specificity; Publication bias; A 943931; H4R antagonist (4-((3R)-3-amino-pyrrolidin-1-yl)-6,7-dihydro-5H-benzo[6,7]cyclohepta[1,2-d]pyrimidin-2-ylamine); ACh; acetylcholine; AKT; protein k

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Weight Loss Upregulates the Small GTPase DIRAS3 in Human White Adipose Progenitor Cells, Which Negatively Regulates Adipogenesis and Activates Autophagy via Akt–mTOR Inhibition

Keywords: آکت; Adipogenesis; Aging; Autophagy; Caloric restriction; DIRAS3; ERK1/2; Human adipose-derived stromal/progenitor cells; IGF-1; Insulin; mTOR; Akt; Obesity; Weight loss

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Oncogenic circuit constituted by Ser31-HBx and Akt increases risks of chronic hepatitis and hepatocellular carcinoma

Keywords: آکت; HBx; Akt; Phosphorylation; Hepatocellular carcinoma;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Mulberry anthocyanin extract ameliorates insulin resistance by regulating PI3K/AKT pathway in HepG2 cells and db/db mice

Keywords: آکت; Mulberry anthocyanins; Glucose metabolism; HepG2 cells; db/db mice; AKT

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Research ArticleEnhanced expression of c-myc in hepatocytes promotes initiation and progression of alcoholic liver disease

Keywords: آکت; 4-HNE; 4-Hydroxynonenal; ACOX; acyl-CoA oxidase; AKT; RAC-alpha serine/threonine protein kinase; alb-myctg; transgenic mice with overexpression of c-myc in hepatocytes; ALD; alcoholic liver disease; ALT; alanine aminotransferase; Asns; asparagine syntheth

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

The broken “Off” switch in cancer signaling: PP2A as a regulator of tumorigenesis, drug resistance, and immune surveillance

Keywords: آکت; PP2A; AKT; CIP2A; SET; Cell cycle; Immune surveillance; Drug resistance

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Research reportThe flavonoid baicalein rescues synaptic plasticity and memory deficits in a mouse model of Alzheimer's disease

Keywords: آکت; AD; Alzheimer's disease; ACSF; artificial cerebrospinal fluid; Akt; serine threonine Kinase; APP; amyloid precursor protein; Aβ; β-amyloid; BACE1; β-secretase enzyme; Bai; baicalein; fEPSP; field excitatory postsynaptic potential; GluR1; α-amino-3-h

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Glucose-Induced Oxidative Stress Reduces Proliferation in Embryonic Stem Cells via FOXO3A/β-Catenin-Dependent Transcription of p21cip1

Keywords: آکت; glucose; oxidative stress; proliferation; FOXO; β-catenin; embryonic stem cell; metabolism; AKT; c-jun kinase

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Research reportThe antidepressant-like effect of alarin is related to TrkB-mTOR signaling and synaptic plasticity

Keywords: آکت; GALP; galanin-like peptide; mTOR; mammalian target of rapamycin; TrkB; tropomyosin-related kinase B; ERK; extracellular signal-regulated kinase; AKT; protein kinase B; p70S6K; ribosomal protein S6 kinase; 4E-BP1; eukaryotic initiation factor 4E binding pr

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Non-genomic oestrogen receptor signal in B lymphocytes: An approach towards therapeutic interventions for infection, autoimmunity and cancer

Keywords: آکت; mER; membrane bound oestrogen receptor; GPER; G-protein coupled oestrogen receptor; PIP2; phosphatidylinositol 4,5-biphosphate; IP3; inositol triphosphate; PI3 kinase; phosphoinositide 3-kinase; Akt; protein kinase B a Serine/Threonine specific protein ki

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Activation of type 5 metabotropic glutamate receptor promotes the proliferation of rat retinal progenitor cell via activation of the PI-3-K and MAPK signaling pathways

Keywords: آکت; AKT; protein kinase B; AMD; age-related macular degeneration; bFGF; basic fibroblast growth factor; BrdU; 5-Bromo-2-deoxyUridine; DHPG; (S)-3,5-dihydroxyphenylglycine hydrate; DMEM/F12; Dulbecco's Modified Eagle's Medium and Hams F12; EGF; epidermal g

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Insulin-like growth factor 1 rescues R28 retinal neurons from apoptotic death through ERK-mediated BimEL phosphorylation independent of Akt

Keywords: آکت; Neuroprotection; Insulin-like growth factor 1; PI3K; Akt; MAPK; ERK; Bim;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Protective effect of carnosic acid against paraquat-induced redox impairment and mitochondrial dysfunction in SH-SY5Y cells: Role for PI3K/Akt/Nrf2 pathway

Keywords: آکت; Paraquat; Carnosic acid; Mitochondria; Oxidative stress; Akt; Nrf2;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Nanomedicine of synergistic drug combinations for cancer therapy - Strategies and perspectives

Keywords: آکت; Nanomedicine; Synergistic drug combinations; Cancer therapy; Strategies; Perspectives; ADC; antibody-drug conjugate; Akt; serine/threonine-specific protein kinase, or known as protein kinase B; BD; biodistribution; CI; combination index; cRGD Peptide; cyc

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

Aβ-Induced Drp1 phosphorylation through Akt activation promotes excessive mitochondrial fission leading to neuronal apoptosis

Keywords: آکت; Aβ; Amyloid β; AD; Alzheimer's disease; Akt; protein kinase B; AraC; cytosine arabinoside; ATP; adenosine triphosphate; CaM; calmodulin; CaMKIα; Ca2 +/calmodulin-dependent kinase type 1 alpha; CaMKII; Ca2 +/calmodulin-dependent kinase type II; CDK; c

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

A Frameshift in CSF2RB Predominant Among Ashkenazi Jews Increases Risk for Crohn's Disease and Reduces Monocyte Signaling via GM-CSF

Keywords: آکت; IBD; Inflammatory Bowel Disease; Risk Factor; Ethnic Variation; AJ; Ashkenazi Jewish; AKT; AK strain transforming; CD; Crohn's disease; CRC; colorectal cancer; CSF2RA; CSF-receptor, α chain; CSF2RB; CSF-receptor, β chain; CyTOF; time-of-flight mass cyto

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2016 سفارش ترجمه

BCKA down-regulates mTORC2-Akt signal and enhances apoptosis susceptibility in cardiomyocytes

Keywords: آکت; Diabetes; Isoproterenol; BCKA; Apoptosis; mTORC2; Akt;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2016 سفارش ترجمه

PI3K-AKT signaling pathway is involved in hypoxia/thermal-induced immunosuppression of small abalone Haliotis diversicolor

Keywords: آکت; Haliotis diversicolor; Immunosuppression; PI3K; AKT; Thermal; Hypoxia; Bacterial challenge;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2016 سفارش ترجمه

SC79 rescues osteoblasts from dexamethasone though activating Akt-Nrf2 signaling

Keywords: آکت; Dexamethasone (Dex); SC79; Akt; Oxidant stress; Nrf2;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2016 سفارش ترجمه

Loganin possesses neuroprotective properties, restores SMN protein and activates protein synthesis positive regulator Akt/mTOR in experimental models of spinal muscular atrophy

Keywords: آکت; SMN; survival motor neuron; SMA; spinal muscular atrophy; Akt; protein kinase B; ERK; extracellular signal-regulated kinases; GSK-3β; glycogen synthase kinase-3 beta; CREB; cAMP response element-binding protein; Elk-1; ETS-like transcription factor; BDNF

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2016 سفارش ترجمه

Autophagy prevention sensitizes AKTi-1/2-induced anti-hepatocellular carcinoma cell activity in vitro and in vivo

Keywords: آکت; Hepatocellular carcinoma; AKT; AKTi-1/2; Autophagy and chemo-sensitization;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2016 سفارش ترجمه

Nuclear factor-κB-dependent microRNA-130a upregulation promotes cervical cancer cell growth by targeting phosphatase and tensin homolog

Keywords: آکت; NF-κB; Cervical cancer; miR-130a; PTEN; AKT; Tumorigenesis;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2016 سفارش ترجمه

Disruption of ATP-sensitive potassium channel function in skeletal muscles promotes production and secretion of musclin

Keywords: آکت; Action potential; Calcium; Natriuretic peptide; Fatty acid; Endurance; AKT; protein kinase B; ANP; atrial natriuretic peptide; ATP; adenosine triphosphate; CaMKII; calcium/calmodulin-dependent protein kinase II; FOXO1; forkhead box O1 transcription factor

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2016 سفارش ترجمه

Polymerase delta-interacting protein 2 regulates collagen accumulation via activation of the Akt/mTOR pathway in vascular smooth muscle cells

Keywords: آکت; Akt; protein kinase B; Atg; autophagy-related gene; ECM; extracellular matrix; 4E-BP1; eukaryotic initiation factor 4E binding protein 1; eIF4E; eukaryotic translation initiation factor 4E; Hsc70; heat shock cognate protein 70; LC3B; microtubule-associate

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2016 سفارش ترجمه

Effects and mechanisms of melatonin on the proliferation and neural differentiation of PC12 cells

Keywords: آکت; Melatonin; PC12 cells; Neuronal differentiation; ERK1/2; AKT;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2016 سفارش ترجمه