دانلود مقالات ISI درباره آکت + ترجمه فارسی

Cognitive impairments following cranial irradiation can be mitigated by treatment with a tropomyosin receptor kinase B agonist

Keywords: آکت; DHF; 7,8-dihydroxyflavone; BDNF; brain-derived neurotrophic factor; TrkB; tropomycin receptor kinase B; ERK; extracellular signal-regulated kinase; AKT; protein kinase B; PSD-95; post-synaptic density 95; SGZ; subgranular zone; BrdU; bromodeoxyuridine; Dc

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2016 سفارش ترجمه

Combined inhibition of the EGFR/AKT pathways by a novel conjugate of quinazoline with isothiocyanate

Keywords: آکت; EGFR-TK inhibitors; Multitarget agents; Sulforaphane; Isothiocyanate; Akt phosphorylation; EGFR-TK; epidermal growth factor receptor; EGFR-TKI; epidermal growth factor receptor inhibitor; MET; mesenchymal-epithelial transition factor; PI3K; phosphatidyl

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2016 سفارش ترجمه

Gamma-glutamylcyclotransferase promotes the growth of human glioma cells by activating Notch-Akt signaling

Keywords: آکت; GGCT; Glioma; Notch; Akt;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2016 سفارش ترجمه

Performance of a phosphoflow assay to determine phosphorylation of S6 ribosomal protein as a pharmacodynamic read out for mTOR inhibition

Keywords: آکت; Akt; protein kinase B; BSA; bovine serum albumin; CRP; C-reactive protein; CsA; cyclosporine A; CV; coefficient of variation; EDTA; ethylenediaminetetraacetic acid; ELISA; enzyme-linked, immunosorbent assay; ERK; extracellular signal-regulated kinase; Evr

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2016 سفارش ترجمه

The dipeptide Pro-Asp promotes IGF-1 secretion and expression in hepatocytes by enhancing JAK2/STAT5 signaling pathway

Keywords: آکت; Dipeptide; Pro-Asp; IGF-1; Hepatocytes; JAK2/STAT5; Akt; protein kinase B; Asp; aspartic acid; ERK; extracellular signal-regulated kinase; GH; growth hormone; IGF-1; insulin-like growth factor 1; JAK2; Janus kinase 2; PepT1; peptide transporter 1; PepT2;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2016 سفارش ترجمه

ANGPTL8/betatrophin alleviates insulin resistance via the Akt-GSK3β or Akt-FoxO1 pathway in HepG2 cells

Keywords: آکت; ANGPTL8/betatrophin; Akt; GSK3β; FoxO1; Insulin resistance; HepG2 cells;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2016 سفارش ترجمه

Unravelling exemestane: From biology to clinical prospects

Keywords: آکت; AI(s); aromatase inhibitor (s); AKT; protein kinase B; AREG; amphiregulin; BMD; bone mineral density; CYP; cytochrome P450; DHEAS; dehydroepiandrosterone sulfate; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; EMA; European Medicine

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2016 سفارش ترجمه

Subchronic administration of ascorbic acid elicits antidepressant-like effect and modulates cell survival signaling pathways in mice

Keywords: آکت; Antidepressant; AKT; Ascorbic acid; p38MAPK; Tail suspension test;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2016 سفارش ترجمه

Pelota Regulates Epidermal Differentiation by Modulating BMP and PI3K/AKT Signaling Pathways

Keywords: آکت; AKT; protein kinase B; BMP; bone morphogenetic protein; CE; cornified envelope; E; embryonic day; EPB; epidermal permeability barrier; FLG; filaggrin; pAKT; phospho-AKT; Pelo; Pelota; PI3K; phosphoinositide 3-kinase; pSMAD; phospho-SMAD; SC; stratum corne

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2016 سفارش ترجمه

Overexpression of PRAS40T246A in the Proliferative Compartment Suppresses mTORC1 Signaling, Keratinocyte Migration, and Skin Tumor Development

Keywords: آکت; Ace; acetone; Akt; acutely transforming retrovirus AKT8 in rodent T-cell lymphoma; BK5; bovine keratin 5; DMBA; 7,12-dimethylbenz[a]anthracene; LRC; label retaining cell; PRAS40; proline-rich Akt substrate of 40 kDa; TPA; 12-O-tetradecanoylphorbol-13-acet

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2016 سفارش ترجمه

The cytoprotective effect of biglycan core protein involves Toll-like receptor 4 signaling in cardiomyocytes

Keywords: آکت; TLR4; Toll-like receptor 4; SI/R; simulated ischemia/reperfusion injury; rhBGNc; recombinant human biglycan core protein; GAG; glycosaminoglycan; TGFβ; transforming growth factor-beta; BSA; bovine serum albumin; D-PBS; Dulbecco's phosphate-buffered salin

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2016 سفارش ترجمه

Akt phosphorylates myc-associated zinc finger protein (MAZ), releases P-MAZ from the p53 promoter, and activates p53 transcription

Keywords: آکت; p53; Arf; Mdm2; Akt; MAZ; Phosphorylation; ChIP; chromatin immunoprecipitation; Dox; doxycycline; EMSA; electrophoretic mobility shift assay; IB; immunoblotting; IP; immunoprecipitation; Myr-Akt; myristoylatedAkt; siRNA; small interference RNA; WB; Wester

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2016 سفارش ترجمه

Improvement of Sclerodermatous Graft-Versus-Host Disease in Mice by Niclosamide

Keywords: آکت; Ab; antibody; AKT; acutely transforming retrovirus AKT8 in rodent T-cell lymphoma; ALT; Alanine aminotransferase; AU; arbitrary unit; cGVHD; chronic GVHD; eGFP; enhanced green fluorescent protein; ERK; extracellular signal-regulated kinase; GVHD; graft-ve

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2016 سفارش ترجمه

Effect of the pituitary adenylate cyclase-activating polypeptide on the autophagic activation observed in in vitro and in vivo models of Parkinson's disease

Keywords: آکت; Akt; protein kinase B; Bcl-2; B-cell lymphoma 2 anti-apoptotic protein; DA; dopaminergic; DAPI; 2-(4-amidinophenyl)-1 H-indole-6-carboxamidine hydrochloride; FBS; fetal bovine serum; GFP; green fluorescent protein; JNK; c-Jun. N-terminal kinase; LC3 I an

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2016 سفارش ترجمه

Induced cortical neurogenesis after focal cerebral ischemia - Three active components from Huang-Lian-Jie-Du Decoction

Keywords: آکت; HLJDD; Huang-Lian-Jie-Du-Decoction; BrdU; 5-bromodeoxyuridine; TCM; Traditional Chinese Medicine; pMACO; permanent middle cerebral artery occlusion; CNS; Central Nervous System; VEGF; Vascular Endothelial Growth Factor; Ang; Angiopoietin; qRT-PCR; quantit

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2016 سفارش ترجمه

Class I PI3-kinase or Akt inhibition do not impair axonal polarization, but slow down axonal elongation

Keywords: آکت; Akt; PI3K; mTORC1; Signalling; Axon establishment; Polarity;

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2016 سفارش ترجمه

Berberine treatment attenuates the palmitate-mediated inhibition of glucose uptake and consumption through increased 1,2,3-triacyl-sn-glycerol synthesis and accumulation in H9c2 cardiomyocytes

Keywords: آکت; BBR; berberine; BSA; bovine serum albumin; DAG; 1,2-diacyl-sn-glycerol; DGAT; 1,2-diacyl-sn-glycerol acyltransferase-2; GLUT-4; glucose transporter-4; LPC; lysophosphatidylcholine; PAL; palmitate; PC; phosphatidylcholine; PE; phosphatidylethanolamine; SM;

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2016 سفارش ترجمه

Nucleoprotein supplementation enhances the recovery of rat soleus mass with reloading after hindlimb unloading-induced atrophy via myonuclei accretion and increased protein synthesis

Keywords: آکت; Nucleoproteins; rpS6; Cell differentiation; Hindlimb suspension; Rat; Akt; protein kinase B; CSAs; cross-sectional areas; mTOR; mammalian target of rapamycin; MyoD; myoblast determination protein; Pax7; transcription factors paired-box 7; PBS; phosphate-b

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2016 سفارش ترجمه

Loss of CRABP-II Characterizes Human Skin Poorly Differentiated Squamous Cell Carcinomas and Favors DMBA/TPA-Induced Carcinogenesis

Keywords: آکت; AKT; v-akt murine thymoma viral oncogene homolog 1; pAKT; phosphorylated AKT; ATRA; all-trans retinoic-acid; CRABP-II; cellular retinoic acid binding protein-II; CRBP-I; cellular retinol binding protein-I; DMBA; 7,12-dimethylbenz[a]anthracene; EGF; epider

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2016 سفارش ترجمه

Cucurbitacin E ameliorates hepatic fibrosis in vivo and in vitro through activation of AMPK and blocking mTOR-dependent signaling pathway

Keywords: آکت; CuE; Cucurbitacin E; ECM; extracellular matrix; HSCs; Hepatic stellate cells; TNF-α; tumor necrosis factor-α; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; PARP; poly ADP-ribose polymerase; MAPK; mitogen activated protein kinase; ER

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2016 سفارش ترجمه

Molecular characterization and functional analysis of BdFoxO gene in the oriental fruit fly, Bactrocera dorsalis (Diptera: Tephritidae)

Keywords: آکت; TOR; target of rapamycin; JNK; Jun NH2-terminal kinase; FoxO; forkhead box O; InR; insulin receptor; Akt; protein kinase B; PI3K; phosphatidylinositol 3-kinase; 4EBP; 4E binding protein; ILPs; insulin-like peptides; RT-qPCR; reverse transcription-quantita

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2016 سفارش ترجمه

Estrogen receptor alpha transcriptionally activates casein kinase 2 alpha: A pivotal regulator of promyelocytic leukaemia protein (PML) and AKT in oncogenesis

Keywords: آکت; CK2; Casein Kinase 2; PML; Promyelocytic Leukemia; TBCA; (E)-3-(2,3,4,5-Tetrabromophenyl) acrylic acid; qRT-PCR; quantitative real time polymerase chain reaction; WCL; Whole cell lysate; SDS-PAGE; Sodium Dodecyl Sulphate Polyacrylamide Gel Electrophoresis

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2016 سفارش ترجمه

Kalirin is required for BDNF-TrkB stimulated neurite outgrowth and branching

Keywords: آکت; Rho GEF; Kalrn knockout; TrkB kinase; TrkB phosphorylation; ERK; Akt; CREB;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2016 سفارش ترجمه

PDE4 Inhibition as Potential Treatment of Epidermolysis Bullosa Acquisita

Keywords: آکت; Akt; RAC-alpha serine/threonine-protein kinase; COL7; type VII collagen; EBA; epidermolysis bullosa acquisita; IC; immune complex; MAPK; mitogen-activated protein kinase; PD; pemphigoid disease; PDE4; phosphodiesterase-4; PMA; phorbol 12-myristate 13-acet

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2016 سفارش ترجمه

Pharmacological postconditioning against myocardial infarction with a slow-releasing hydrogen sulfide donor, GYY4137

Keywords: آکت; GYY4137-Morphilino salt (PubChem CID: 469337261); LY294002 (PubChem CID: 3973); N-Nitro-l-arginine methyl ester hydrochloride (PubChem: 39836); AAR; area at risk; Akt; protein kinase B; DATS; diallyltrisulfide; eNOS; endothelial nitric oxide synthase; ERK

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2016 سفارش ترجمه

Lack of mitochondrial DNA impairs chemical hypoxia-induced autophagy in liver tumor cells through ROS-AMPK-ULK1 signaling dysregulation independently of HIF-1α

Keywords: آکت; Akt; protein kinase B; AMPK; AMP-activated protein kinase; AVOs; acidic vesicular organelles; BNIP3; BCL2/adenovirus E1B 19 kDa interacting protein 3; BNIP3L; BCL2/adenovirus E1B 19 kDa interacting protein 3-like; CCND1; cyclin D1; CFSE; 5-(6)-carboxyfl

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2016 سفارش ترجمه

The p21-activated kinase, PAK2, is important in the activation of numerous pancreatic acinar cell signaling cascades and in the onset of early pancreatitis events

Keywords: آکت; CCK; COOH-terminal octapeptide of cholecystokinin; TPA; 12-O-tetradecanoylphorbol-13-acetate; PAK; p21-activated kinases; SFK; Src family of kinases; PKC; protein kinase C; PYK2; proline-rich tyrosine kinase 2; FAK; focal adhesion kinase; SHC; Src homolog

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2016 سفارش ترجمه

6-(3,4-Dihydro-1H-isoquinoline-2-yl)-N-(6-methoxypyridine-2-yl) nicotinamide-26 (DIMN-26) decreases cell proliferation by induction of apoptosis and downregulation of androgen receptor signaling in human prostate cancer cells

Keywords: آکت; 6-(3,4-dihydro-1H-isoquinoline-2-yl)-N-(6 methoxypyridine-2-yl) nicotinamide-26; Androgen receptor; Prostate cancer; Apoptosis; G2/M arrest; AKT;

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2016 سفارش ترجمه

An overview of chemical inhibitors of the Nrf2-ARE signaling pathway and their potential applications in cancer therapy

Keywords: آکت; AA; Ascorbic acid; AEM1; ARE expression modulator 1; AEG1; Astrocyte elevated gene-1; Akt; Protein kinase B; AMPK; AMP-activated protein kinase; APL; Acute promyelocytic leukemia; ARE; Antioxidant response element; ATO; Arsenic trioxide; Bach; BTB and CNC

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2016 سفارش ترجمه

Effects of mutations in Wnt/β-catenin, hedgehog, Notch and PI3K pathways on GSK-3 activity-Diverse effects on cell growth, metabolism and cancer

Keywords: آکت; GSK-3; Wnt/beta-catenin; PI3K; Akt; mTOR; Hedgehog; Notch; Targeted therapy; Therapy resistance;

دانلود رایگان متن کامل مقاله ISI 158 صفحه سال انتشار : 2016 سفارش ترجمه

CXCR3: Latest evidence for the involvement of chemokine signaling in bone cancer pain

Keywords: آکت; Bone cancer pain; Chronic pain; Chemokine; CXCR3; Akt; ERK;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2015 سفارش ترجمه

MicroRNA-133a improves the cardiac function and fibrosis through inhibiting Akt in heart failure rats

Keywords: آکت; miR-133a; Fibrosis; Akt; Heart failure

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

YB-1 overexpression promotes a TGF-β1-induced epithelial-mesenchymal transition via Akt activation

Keywords: آکت; YB-1; TGF-β1; Epithelial-mesenchymal transition; E-cadherin; Akt;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Expression of ROR1, pAkt, and pCREB in gastric adenocarcinoma

Keywords: آکت; ROR1; Akt; CREB; Adenocarcinoma; Stomach

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Expression of human olfactory receptor 10J5 in heart aorta, coronary artery, and endothelial cells and its functional role in angiogenesis

Keywords: آکت; Olfactory receptor; OR10J5; Angiogenesis; AKT; Calcium; HUVEC;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Erythropoietin activates the phosporylated cAMP [adenosine 3′5′ cyclic monophosphate] response element-binding protein pathway and attenuates delayed paraplegia after ischemia-reperfusion injury

Keywords: آکت; 19; 38; AKT; serine/threonine-specific kinase; BCL-2; B-cell lymphoma 2; BDNF; brain-derived neurotrophic factor; CREB; cAMP [adenosine 3′5′ cyclic monophosphate] response element-binding protein; EPO; erythropoietin; pAKT; phosphorylated AKT; pCREB;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Sulforaphane induces apoptosis in adipocytes via Akt/p70s6k1/Bad inhibition and ERK activation

Keywords: آکت; Sulforaphane; Adipocyte; Apoptosis; Akt; ERK;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Impaired degradation of WNK by Akt and PKA phosphorylation of KLHL3

Keywords: آکت; PKA; Akt; KLHL3; WNK4; Insulin;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Echinacea purpurea root extract inhibits TNF release in response to Pam3Csk4 in a phosphatidylinositol-3-kinase dependent manner

Keywords: آکت; Akt; Echinacea; Polysaccharide; Pam3Csk4; PI3K; THP-1;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Differential regulation of Connexin50 and Connexin46 by PI3K signaling

Keywords: آکت; Connexin; Lens; Gap junction; PI3K; Akt

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Decreased AKT1/mTOR pathway mRNA expression in short-term bipolar disorder

Keywords: آکت; Bipolar disorder; AKT; mTOR; Lithium; Treatment; Depression;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

EZH2 phosphorylation regulates Tat-induced HIV-1 transactivation via ROS/Akt signaling pathway

Keywords: آکت; HIV-1; Enhancer of zeste homolog 2; Reactive oxygen species; AKT;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Akt and cAMP response element binding protein mediate 17β-estradiol regulation of glucose transporter 3 expression in human SH-SY5Y neuroblastoma cell line

Keywords: آکت; Glucose transporter 3; 17β-estradiol; Alzheimer's disease; Neuron; Akt; cAMP response element binding protein;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

AKT and MET signalling mediates antiapoptotic radioresistance in head neck cancer cell lines

Keywords: آکت; Head neck cancer; Irradiation; Apoptosis; Stem cells; AKT; MET; ALDH;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

The protective effect of GLP-1 analogue in arterial calcification through attenuating osteoblastic differentiation of human VSMCs

Keywords: آکت; Vascular smooth muscle cells; Calcification; Osteoblastic differentiation; Glucagon-like peptide-1; siRNA; PI3K; Akt; mTOR;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

TRAF6 is required for the GM-CSF-induced JNK, p38 and Akt activation

Keywords: آکت; GM-CSF; TRAF6; JNK; p38; Akt

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Multiple proliferation-survival signalling pathways are simultaneously active in BRAF V600E mutated thyroid carcinomas

Keywords: آکت; Thyroid carcinoma; BRAF; cell signalling pathway; ERK; AKT

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Schisandrin B suppresses glioma cell metastasis mediated by inhibition of mTOR/MMP-9 signal pathway

Keywords: آکت; Akt; mTOR; Cell invasion; Cell migration; PI3K

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Inhibitory effects of PPARγ ligands on TGF-β1-induced CTGF expression in cat corneal fibroblasts

Keywords: آکت; Rosiglitazone; Troglitazone; 15d-PGJ2; JNK; p38 MAPK; ERK; AKT; CTGF; connective tissue growth factor; CCN; cyr61, ctgf, neuroblastoma over-expressed gene; Nov; neuroblastoma over-expressed gene; ECM; extracellular matrix; PRK; photorefractive keratectomy

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Evidence that the MEK/ERK but not the PI3K/Akt pathway is required for protection from myocardial ischemia-reperfusion injury by 3′,4′-dihydroxyflavonol

Keywords: آکت; Flavonol; Myocardial ischemia/reperfusion injury; Oxidative stress; Survival kinases; ERK1/2; Akt; PD98059; LY294002;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه