دانلود مقالات ISI درباره آکت + ترجمه فارسی

MiR-145 functions as a tumor suppressor targeting NUAK1 in human intrahepatic cholangiocarcinoma

Keywords: آکت; MiR-145; NUAK1; Intrahepatic cholangiocarcinoma; AKT; Matrix metalloproteinase protein;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Dasatinib enhances cisplatin sensitivity in human esophageal squamous cell carcinoma (ESCC) cells via suppression of PI3K/AKT and Stat3 pathways

Keywords: آکت; ESCC; Dasatinib; Cisplatin; AKT; Stat3

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

5,3′-Dihydroxy-6,7,4′-trimethoxyflavanone exerts its anticancer and antiangiogenesis effects through regulation of the Akt/mTOR signaling pathway in human lung cancer cells

Keywords: آکت; Akt; Angiogenesis; Apoptosis; Lung cancer cells; 5,3′-Dihydroxy-6,7,4′-trimethoxyflavanone;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Alpha-lipoic acid activates eNOS through activation of PI3-kinase/Akt signaling pathway

Keywords: آکت; Lipoic acid; eNOS; Akt; Phosphorylation; Endothelium;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

AML sensitivity to YM155 is modulated through AKT and Mcl-1

Keywords: آکت; YM155; Akt; XIAP; Bcl-2; Mcl-1; AML;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Research ReportRosiglitazone attenuates early brain injury after experimental subarachnoid hemorrhage in rats

Keywords: آکت; SAH; subarachnoid hemorrhage; EBI; early brain injury; PPARγ; peroxisome proliferator-activated receptor γ; BBB; blood brain barrier; PI3K; phosphoinositide 3-kinase; Akt; protein kinase B; p-Akt; phosphorylated Akt; MMP-9; matrix metallopeptidase 9; DI

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Downregulation of key regulatory proteins in androgen dependent prostate tumor cells by oncolytic reovirus

Keywords: آکت; Hypoxia; Prostate cancer; Reovirus; Androgen receptor; PSA; Akt;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Gardenamide A attenuated cell apoptosis induced by serum deprivation insult via the ERK1/2 and PI3K/AKT signaling pathways

Keywords: آکت; Akt; protein kinase B; DCFH-DA; 2,7-dichlorodihydrofluorescein diacetate; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethylsulfone; eNOS; endothelial NO synthase; ERK; extracellular signal-regulated kinase; GA; Gardenamide A; IGF-1; insulin-lik

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

ShcC proteins: Brain aging and beyond

Keywords: آکت; ShcC adaptor proteins; Signaling; Aging; Brain ischemia; Brain tumors; Immunity; Aβ; beta-amyloid; AD; Alzheimer's disease; Akt; protein kinase B (PKB); ALK; anaplastic lymphoma kinase (receptor tyrosine kinase); APP; alpha-amyloid precursor protein; ARD

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

The anti-tumour activity of rLj-RGD4, an RGD toxin protein from Lampetra japonica, on human laryngeal squamous carcinoma Hep-2 cells in nude mice

Keywords: آکت; rLj-RGD4; Laryngeal squamous carcinoma; Anti-tumour; Hep-2; Nude mice; RGD; Arg-Gly-Asp; rLj-RGD4; recombinant Lampetra japonica (Arg-Gly-Asp) 4; TUNEL; terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end labelling; MVD; intratumoural micr

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Lewis y enhances CAM-DR in ovarian cancer cells by activating the FAK signaling pathway and upregulating Bcl-2/Bcl-XL expression

Keywords: آکت; Lewis y; CAM-DR; Integrin α5β1; FAK signaling pathway; Bcl-2; ECM; extracellular matrix; CAM-DR; cell adhesion-mediated drug resistance; FN; fibronectin; FAK; focal adhesion kinase; PI3K; phosphatidyl inositol 3-kinase; Akt; protein kinase B; ERK; extra

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

ReviewCo-targeting cancer drug escape pathways confers clinical advantage for multi-target anticancer drugs

Keywords: آکت; Afatinib (Pubmed CID: 10184653); Erlotinib (Pubmed CID: 176870); Gefitinib (Pubmed CID: 123631); Pazopanib (Pubmed CID: 10113978); XL647 (Pubmed CID: 10458325); Lenvatinib (Pubmed CID: 9823820); Abl; Abelson murine leukemia viral oncogene homolog 1; AKT;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Illite improves memory impairment and reduces Aβ level in the Tg-APPswe/PS1dE9 mouse model of Alzheimer׳s disease through Akt/CREB and GSK-3β phosphorylation in the brain

Keywords: آکت; Alzheimer׳s disease; Illite; Beta-amyloid; Lithium; CREB; Akt;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

GTS-21 attenuates lipopolysaccharide-induced inflammatory cytokine production in vitro by modulating the Akt and NF-κB signaling pathway through the α7 nicotinic acetylcholine receptor

Keywords: آکت; GTS-21; RAW264.7 cells; Inflammation; NF-κB; Akt; α7 nicotinic acetylcholine receptor;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

A review on the possible molecular mechanism of action of N-acetylcysteine against insulin resistance and type-2 diabetes development

Keywords: آکت; N-acetyl-l-cysteine (NAC) (PubChem CID: 12035); AKT; protein kinase B; AP-1; activator protein 1; CCL2; chemokine (C-C motif) ligand 2; eNOS; endothelial nitric oxide synthase; ERK; extracellular signal-regulated kinase; FFA; free fatty acid; GLUT; gluc

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Targeting cholesterol with β-cyclodextrin sensitizes cancer cells for apoptosis

Keywords: آکت; Cancer; Phosphoinositide 3-kinase; AKT; Epidermal growth factor; Insulin-like growth factor 1; Receptor tyrosine kinase; Pro-survival signal; Apoptosis; Beta-cyclodextrin; 2-Deoxyglucose; Bcl2; Mcl1; ABT-263; TNF-related apoptosis-inducing ligand; Mitocho

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Dual inhibition of allosteric mitogen-activated protein kinase (MEK) and phosphatidylinositol 3-kinase (PI3K) oncogenic targets with a bifunctional inhibitor

Keywords: آکت; Dual inhibition; Akt; ERK; PI-3 Kinase; MEK1; MAP Kinase; Oncogenic signaling; KRAS; Driven oncogenesis;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Acemannan accelerates cell proliferation and skin wound healing through AKT/mTOR signaling pathway

Keywords: آکت; Acemannan; Wound healing; AKT; mTOR; Cyclin D1

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Pretreatment with low dose etomidate prevents etomidate-induced rat adrenal insufficiency by regulating oxidative stress-related MAPKs and apoptosis

Keywords: آکت; Etomidate; Adrenal gland insufficiency; Oxidative stress; MAPK; AKT

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Naringenin suppresses TPA-induced tumor invasion by suppressing multiple signal transduction pathways in human hepatocellular carcinoma cells

Keywords: آکت; ERK; JNK; PI3K; AKT; NF-κB; AP-1

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Akt-dependent Girdin phosphorylation regulates repair processes after acute myocardial infarction

Keywords: آکت; Girdin; Akt; Cardiac fibroblast; Myocardial infarction; Cardiac tissue rupture

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Docosahexaenoic acid inhibits proteolytic processing of sterol regulatory element-binding protein-1c (SREBP-1c) via activation of AMP-activated kinase

Keywords: آکت; SREBP; Sterol regulatory element binding protein; AMPK; AMPK-activated kinase; DHA; Docosahexaenoic Acid; PUFA; Polyunsaturated fatty acids; Akt; Akt/Protein Kinase B; mTORC1; Mammalian target of rapamycin complex 1; p70S6K; p70S6Kinase; T2DM; Type II Dia

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Tomosyn is a novel Akt substrate mediating insulin-dependent GLUT4 exocytosis

Keywords: آکت; GLUT4; glucose transporter 4; EGFP; enhanced green fluorescence protein; GST; glutathione S-transferase; PKA; protein kinase A; SDS-PAGE; sodium dodecyl sulfate-polyacrylamide gel electrophoresis; SNARE; soluble NSF-attachment protein receptors; SNAP-25;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Photoactivation of TAZ via Akt/GSK3β signaling pathway promotes osteogenic differentiation

Keywords: آکت; LPLI; low-power laser irradiation; ALP; alkaline phosphatase; BMP2; bone morphogenetic protein 2; Cbfa1; core-binding factor 1; CK1; casein kinase 1; DEX; dexamethasone; GSK3β; glycogen synthase kinase 3β; LATS; large tumor suppressor; MyoD; myogenic di

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Calcineurin B homologous protein 3 negatively regulates cardiomyocyte hypertrophy via inhibition of glycogen synthase kinase 3 phosphorylation

Keywords: آکت; Akt; protein kinase B; ANP; atrial natriuretic peptide; CaMKII; Ca2 +/calmodulin-dependent protein kinase II; CHP3; calcineurin B homologous protein 3; DAPI; 4′,6-diamidino-2-phenylindole dihydrochloride; DMEM; Dulbecco's modified Eagle's medium; FBS;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Down-regulation of ERK1/2 and AKT-mediated X-ray repair cross-complement group 1 protein (XRCC1) expression by Hsp90 inhibition enhances the gefitinib-induced cytotoxicity in human lung cancer cells

Keywords: آکت; CFA; colony-forming ability; EGFR; epidermal growth factor receptor; Hsp; heat shock protein; MAPK; mitogen-activated protein kinase; NSCLC; non-small cell lung cancer; siRNA; small interfering RNA; XRCC1; X-ray repair cross-complement group 1 protein; XR

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

The natural tumorcide Manumycin-A targets protein phosphatase 1α and reduces hydrogen peroxide to induce lymphoma apoptosis

Keywords: آکت; Manumycin-A; Natural tumoricide; Lymphoma; Apoptosis; Protein phosphatase 1α, PP1α; Reactive oxygen species; Hydrogen peroxide; Superoxide; MEK; Akt;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

BCL-2 family protein, BAD is down-regulated in breast cancer and inhibits cell invasion

Keywords: آکت; AIF; apoptosis inducible factor; AP-1; activator protein-1; AKT; protein kinase B; Apaf-1; apoptosis protease activating factor-1; BAD; Bcl-2-associated death promoter; BCL-2; B-cell lymphoma 2; BCLxL; B-cell lymphoma-extra large; BH3; Bcl-2 homology doma

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

α-TLR2 antibody attenuates the Aβ-mediated inflammatory response in microglia through enhanced expression of SIGIRR

Keywords: آکت; TLR2; SIGIRR; TIR8; Aβ; Microglia; LTP; Hippocampus; PPARγ; PI3 kinase; Akt;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

PTEN regulates lung endodermal morphogenesis through MEK/ERK pathway

Keywords: آکت; Lung morphogenesis; Branching morphogenesis; Pten; ERK; AKT; Cell migration; Endoderm;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Neuroprotection in Parkinsonian-treated mice via estrogen receptor α activation requires G protein-coupled estrogen receptor 1

Keywords: آکت; 17β-Estradiol; Estrogen receptor; GPER1; MPTP; Neuroprotection; Akt;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Genetic obesity alters recruitment of TANK-binding kinase 1 and AKT into hypothalamic lipid rafts domains

Keywords: آکت; TBK1; Insulin receptor; AKT; Insulin resistance; Hypothalamus and lipotoxicity; Obesity

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Bromo-honaucin A inhibits osteoclastogenic differentiation in RAW 264.7 cells via Akt and ERK signaling pathways

Keywords: آکت; Br-Honaucin A; RAW 264.7; Osteoclastogenesis; RANKL; p38; ERK; Akt

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

TG-interacting factor transcriptionally induced by AKT/FOXO3A is a negative regulator that antagonizes arsenic trioxide-induced cancer cell apoptosis

Keywords: آکت; Arsenic trioxide; Biphasic effects; Negative regulator; TG-interacting factor; AKT; FOXO3A

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Phosphorylation of GSK3α/β correlates with activation of AKT and is prognostic for poor overall survival in acute myeloid leukemia patients

Keywords: آکت; Leukemia; GSK3; AKT; PKC delta; RPPA; Signal transduction

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Hepatic proteomic analysis revealed altered metabolic pathways in insulin resistant Akt1+/−/Akt2−/− mice

Keywords: آکت; IRS, insulin receptor substrate; PI3K, phosphoinositide 3-kinase; 2-D DIGE, two-dimensional differential gel electrophoresis; pI, isoelectric point; MALDI, matrix-assisted laser desorption/ionization; TOF, time of flightMouse; Liver; AKT; Insulin resistan

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Hypoxia-mediated cancer stem cells in pseudopalisades with activation of hypoxia-inducible factor-1α/Akt axis in glioblastoma

Keywords: آکت; Cancer stem cell; Pseudopalisade; HIF-1α; Akt; Glioblastoma

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

The role of PI3K/Akt in human herpesvirus infection: From the bench to the bedside

Keywords: آکت; PI3K; Akt; Herpesvirus; Herpes simplex; Varicella-zoster; Cytomegalovirus; Epstein-Barr virus; Kaposi׳s sarcoma associated herpesvirus;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Two triterpeniods from Cyclocarya paliurus (Batal) Iljinsk (Juglandaceae) promote glucose uptake in 3T3-L1 adipocytes: The relationship to AMPK activation

Keywords: آکت; Triterpenoids; Cyclocarya paliurus; Inflammation; Insulin resistance; Glucose uptake; AMPK; Cyclocaric acid B (CAS No. 182315-46-4); Cyclocarioside H (CAS No. 1403937-87-0); Akt; Protein kinase B; AMPK; AMP-activated protein kinase; AUC; Area under the cu

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Ginsenoside Rg3 antagonizes adriamycin-induced cardiotoxicity by improving endothelial dysfunction from oxidative stress via upregulating the Nrf2-ARE pathway through the activation of akt

Keywords: آکت; Ginsenoside Rg3; Adriamycin; Cardiotoxicity; Oxidative stress; Nrf2; Aortic ring; ADM; adriamycin; AKT; protein kinase B; Bax; Bcl-2 associated X protein; Bcl-2; B cell lymphoma-2; CMEC; cardiac microvascular endothelial cells; eNOS; endothelial nitric ox

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Mitogen-activated protein kinase and Akt pathways are involved in 4-n-nonyphenol induced apoptosis in mouse Sertoli TM4 cells

Keywords: آکت; APEs; alkylphenol polyethoxylates; CAT; catalase; DCF; 2′-7′-dichlorofluorescein; DCFH-DA; 5(6)-carboxy-2′-7′-dichlorofluorescein diacetate; DMEM/F-12; Dulbecco's modified Eagle's medium nutrient mixture F-12 HAM; EDCs; endocrine-disrupting compou

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

RGC-32 is a novel regulator of the T-lymphocyte cell cycle

Keywords: آکت; T-cells; Cell cycle; RGC-32; Knockout mouse; Akt; IL-2;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Obesity and asthma: beyond TH2 inflammation

Keywords: آکت; AHR; airway hyperreactivity; AKT; RAC-alpha serine/threonine-protein kinase; AMPK; adenosine monophosphate-activated kinase; ARPF; airway-related pre-ganglionic fibers; ASM; airway smooth muscle; BAL; bronchoalveolar lavage; BMI; body mass index; BTSM; bo

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Research ArticlePTPN11/Shp2 overexpression enhances liver cancer progression and predicts poor prognosis of patients

Keywords: آکت; HCC; hepatocellular carcinoma; Shp2; Src-homology 2 domain-containing phosphatase 2; DFS; disease free survival; OS; overall survival; PI3-K; phosphoinositide 3-kinase; Akt; v-akt murine thymoma viraloncogene homolog; Hepatocellular carcinoma; Shp2; Metas

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

PI3K/Akt signaling in osteosarcoma

Keywords: آکت; OS; osteosarcoma; PI3K; phosphatidylinositol 3-kinase; PTEN; phosphatase and tensin homolog; mTOR; mammalian target of rapamycin; RTKs; receptor tyrosine kinases; PDGFR; platelet-derived growth factor receptor; IGF1R; insulin-like growth factor 1 receptor

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Role of the Akt/GSK-3β/CRMP-2 pathway in axon degeneration of dopaminergic neurons resulting from MPP+ toxicity

Keywords: آکت; Parkinson׳s disease; Axon degeneration; Pathogenesis; Akt; GSK-3β; CRMP-2

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Chemerin: A comprehensive review elucidating the need for cardiovascular research

Keywords: آکت; AP-4; adaptor protein-4 complex; BMI; body mass index; CRP; C-reactive protein; CPB; carboxypeptidase B; CPN; carboxypeptidase N; CVS; cardiovascular system; C/EBP; CCAAT/enhancer binding protein; CCL; CC chemokine ligands; CSF; cerebrospinal fluid; ChemR

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Control of macrophage metabolism and activation by mTOR and Akt signaling

Keywords: آکت; mTOR; Akt; Macrophage activation; Macrophage metabolism; Immunometabolism

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Heterogeneous expression and biological function of ubiquitin carboxy-terminal hydrolase-L1 in osteosarcoma

Keywords: آکت; UCHL1; Osteosarcoma; Proliferation; Invasion; MAPK/ERK; Akt;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Metformin inhibits age-related centrosome amplification in Drosophila midgut stem cells through AKT/TOR pathway

Keywords: آکت; 4E-BP; eukaryotic translation initiation factor 4E-binding protein; 8-oxo-dG; 8-oxo-2′-deoxyguanosine; AMPK; 5′ AMP-activated protein kinase; EBs; enteroblasts; ECs; enterocytes; EEs; enteroendocrine cells; EGFR; epidermal growth factor receptor; IGF1

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه