دانلود مقالات ISI درباره آکت + ترجمه فارسی

Metformin inhibits age-related centrosome amplification in Drosophila midgut stem cells through AKT/TOR pathway

Keywords: آکت; 4E-BP; eukaryotic translation initiation factor 4E-binding protein; 8-oxo-dG; 8-oxo-2′-deoxyguanosine; AMPK; 5′ AMP-activated protein kinase; EBs; enteroblasts; ECs; enterocytes; EEs; enteroendocrine cells; EGFR; epidermal growth factor receptor; IGF1

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Activation of spinal chemokine receptor CXCR3 mediates bone cancer pain through an Akt-ERK crosstalk pathway in rats

Keywords: آکت; Bone cancer; Pain; CXCR3; ERK; Akt;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Multiwalled carbon nanotube buckypaper induces cell cycle arrest and apoptosis in human leukemia cell lines through modulation of AKT and MAPK signaling pathways

Keywords: آکت; Leukemia cell lines; MWCNT Buckypaper; Cell cycle; Cyclins; AKT; MAPKs;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

The critical role of Akt in cardiovascular function

Keywords: آکت; Akt; Vascular remodeling; Signal transduction;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Melanocytic nevi excised during B-Raf proto-oncogene (BRAF) inhibitor therapy: A study of 19 lesions from 10 patients

Keywords: آکت; B-Raf proto-oncogene inhibition; CD4; CD8; melanocytic nevi; phosphorylated extracellular signal-regulated kinase; phosphorylated protein kinase B; AKT; protein kinase B; BRAF; B-Raf proto-oncogene; MAPK; mitogen-activated protein kinase; NRAS; neuroblast

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Photoactivation of Dok1/ERK/PPARγ signaling axis inhibits excessive lipolysis in insulin-resistant adipocytes

Keywords: آکت; Akt; protein kinase B; Dex; dexamethasone; Dok1; downstream of tyrosine kinases-1; ERK1/2; extracellular signal-regulated kinase 1 and 2; ap2; fatty acid binding protein 4; IBMX; isobutylmethylxanthine; IRS; insulin receptor substrate; InsR; insulin recep

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Phosphatidylinositol-3,4,5-trisphosphate stimulates Ca2 + elevation and Akt phosphorylation to constitute a major mechanism of thromboxane A2 formation in human platelets

Keywords: آکت; (DiC16-PIP3); 1-O-(1,2-di-palmitoyl-sn-glyero-3-O-phosphoryl)-D-myo-inositol-3,4,5-trisphosphate; (DiC8-PIP3); 1-O-(1,2-di-octanoyl-sn-glyero-3-O-phosphoryl)-D-myo-inositol-3,4,5-trisphosphate; (SOCE); store operated Ca2 + entry; (PLC); phospholipase C;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Enhancement effect of resveratrol on the intestinal absorption of bestatin by regulating PEPT1, MDR1 and MRP2 in vivo and in vitro

Keywords: آکت; Res; resveratrol; Mdr1; multidrug resistance 1; Pept1; peptide transporter 1; Mrp2; multidrug resistance-associated protein 2; IGF-1R; insulin-like growth factor 1 receptor; ERK; extracellular signal-regulated kinase; AKT; protein kinase B; ABC; ATP-bindi

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Heterogeneous expression and biological function of ubiquitin carboxy-terminal hydrolase-L1 in osteosarcoma

Keywords: آکت; UCHL1; Osteosarcoma; Proliferation; Invasion; MAPK/ERK; Akt;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

The PI3K/AKT Pathway and Renal Cell Carcinoma

Keywords: آکت; PI3K; AKT; mTOR; Renal cell carcinoma; Targeted therapy

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Mild hypoxia in vivo regulates cardioprotective SUR2A: A role for Akt and LDH

Keywords: آکت; Hypoxia; LDH; Oxygen; SUR2A; Heart; Akt;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Role for the PI3K/Akt/Nrf2 signaling pathway in the protective effects of carnosic acid against methylglyoxal-induced neurotoxicity in SH-SY5Y neuroblastoma cells

Keywords: آکت; Carnosic acid; Methylglyoxal; Oxidative stress; Akt; Nrf2

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Transforming growth factor β-interacting factor-induced malignant progression of hepatocellular carcinoma cells depends on superoxide production from Nox4

Keywords: آکت; Hepatocellular carcinoma; Transforming growth factor β-interacting factor; NADPH oxidase; Reactive oxygen species; AKT; Free radicals;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

MicroRNA-29A/PTEN pathway modulates neurite outgrowth in PC12 cells

Keywords: آکت; DMEM; Dulbecco's Minimum Essential Medium; FBS; Fetal Bovine Serum; GAPDH; Glyceraldehyde-3-Phosphate Dehydrogenase; HBx; hepatitis B virus X; MREs; miRNA response elements; NGF; nerve growth factor; PBS; Phosphate Balanced Solution; PVDF; Polyvinylidene

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Class I PI 3-kinases: Function and evolution

Keywords: آکت; Phosphoinositide; PI3K; AKT; PTEN; Signal Transduction; Cancer; Kinase; Phosphatase; Evolution; Phylogeny;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Natural plant flavonoid apigenin directly disrupts Hsp90/Cdc37 complex and inhibits pancreatic cancer cell growth and migration

Keywords: آکت; Apigenin; Heat shock protein 90; Cell division cycle protein 37; SRL-PFAC; Pancreatic cancer; Apigenin (PubChem CID: 5280443); Galangin (PubChem CID: 5281616); Baicalein (PubChem CID: 5281605); Genistein (PubChem CID: 5280961); Naringenin (PubChem CID: 93

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Research ReportExtracellular α-crystallin protects astrocytes from cell death through activation of MAPK, PI3K/Akt signaling pathway and blockade of ROS release from mitochondria

Keywords: آکت; Akt; protein kinase B; EAE; experimental allergic encephalomyelitis; ERK; extracellular signal-regulated kinase; FCS; fetal calf serum; JNK; c-Jun N-terminal kinases; LDH; lactate dehydrogenase; MAPK; mitogen-activated protein kinases; MEK; mitogen-activa

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Asiaticoside attenuates diabetes-induced cognition deficits by regulating PI3K/Akt/NF-κB pathway

Keywords: آکت; PI3K; phosphoinositide 3-kinase; Akt; protein Kinase B; NF-κB; nuclear Factor -kappa B; STZ; streptozotocin; AChE; acetylcholinesterase; ChAT; choline acetyltransferase; Aβ; amyloid beta; IGF; insulin-like growth factors; Na+-K+-ATPase; Na+-K+-adenosine

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

CCN1 acutely increases nitric oxide production via integrin αvβ3-Akt-S6K-phosphorylation of endothelial nitric oxide synthase at the serine 1177 signaling axis

Keywords: آکت; Endothelial nitric oxide synthase; Nitric oxide; Phosphorylation; CCN1; Integrin; Akt; S6K; Vasodilation; Free radicals;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Growth-factor dependent expression of the translationally controlled tumour protein TCTP is regulated through the PI3-K/Akt/mTORC1 signalling pathway

Keywords: آکت; Translationally controlled tumour protein TCTP; PI 3-kinase pathway; Akt; mTOR complex 1; Initiation factor eIF4E; TOP mRNA

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

The loss of NDRG2 expression improves depressive behavior through increased phosphorylation of GSK3β

Keywords: آکت; NDRG2; N-myc downstream-regulated gene 2; HIF1α; hypoxia-inducible factor 1 α; HSP90; heart shock protein 90; NDRG2; AKT; GSK3β; HIF1α; HSP90;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

In vitro and in vivo anti-inflammatory activity of Phyllanthus acidus methanolic extract

Keywords: آکت; Pa-ME; methanolic extract of Phyllanthus acidus; HPLC; high performance liquid chromatography; PGE2; prostaglandin E2; NO; nitric oxide; COX; cyclooxygenase; iNOS; inducible NO synthase; TLR; Toll-like receptor (TLR); NF-κB; nuclear factor-κB; Akt; prot

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

The protective effect of eupafolin against TNF-α-induced lung inflammation via the reduction of intercellular cell adhesion molecule-1 expression

Keywords: آکت; ERK1/2; extracellular signal-regulated kinase; MAPK; mitogen-activated protein kinase; PI3K; phosphatidylinositol 3-kinase; Eupafolin; Intercellular cell adhesion molecule-1; MAPKs; AKT; Inflammation;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Epibrassinolide alters PI3K/MAPK signaling axis via activating Foxo3a-induced mitochondria-mediated apoptosis in colon cancer cells

Keywords: آکت; AR; Androgen receptor; AZ; Antizyme; AZI; Antizyme inhibitor; AP-1; Activator protein 1; BR; Brassinosteroid; Bcl-2; B-cell lymphoma 2; DiOC6; 3,3′-dihexyloxacarbocyanineiodide; CHENSpm; N1-ethyl-N11-((cycloheptyl)methy)-4,8-diazaundecane; DAPI; 4′,6-

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Piperine blocks interleukin-2-driven cell cycle progression in CTLL-2 T lymphocytes by inhibiting multiple signal transduction pathways

Keywords: آکت; Akt; ERK1/2; IL-2; Piperine; STAT3; STAT5; T lymphocyte

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Insulin upregulates the expression of epithelial sodium channel in vitro and in a mouse model of acute lung injury: Role of mTORC2/SGK1 pathway

Keywords: آکت; AFC; alveolar fluid clearance; AGC; protein kinase A, protein kinase G and protein kinase C; AKT; protein kinase B; ALI; acute lung injury; ARDS; acute respiratory distress syndrome; AT II; type II alveolar epithelial cell; ENaC; epithelial sodium channel

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Plasma membrane gp96 enhances invasion and metastatic potential of liver cancer via regulation of uPAR

Keywords: آکت; mgp96; uPAR; Liver cancer; MAPK; DFS; ADAMTS9; a disintegrin-like and metalloprotease domain with thrombospondin type 1 motifs 9; AIMP1; aminoacyl tRNA synthetase complex-interacting multifunctional protein 1; AKT; v-akt murine thymoma viral oncogene homo

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Overexpression of GRK6 rescues l-DOPA-induced signaling abnormalities in the dopamine-depleted striatum of hemiparkinsonian rats

Keywords: آکت; Parkinson's disease; l-DOPA-induced dyskinesia; GRK6; Lentivirus; ERK1/2; p38; Akt; JNK; ΔFosB;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Research ReportDiallyl trisufide protects against oxygen glucose deprivation -induced apoptosis by scavenging free radicals via the PI3K/Akt -mediated Nrf2/HO-1 signaling pathway in B35 neural cells

Keywords: آکت; DATS; diallyl trisulfide; OGD; oxygen glucose deprivation; Nrf2; nuclear factor E2-related factor 2; HO-1; Heme oxygenase-1; PI3K; phosphatidylinositol 3 kinase; Akt; protein kinase B; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyltetrazolium bromide; DC

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

OGD induced modification of FAK- and PYK2-coupled pathways in organotypic hippocampal slice cultures

Keywords: آکت; OGD; FAK; PYK2; Src; Akt; MAPK

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Cocoa and cocoa flavanol epicatechin improve hepatic lipid metabolism in in vivo and in vitro models. Role of PKCζ

Keywords: آکت; AKT; protein kinase B; AMPK; AMP-activated protein kinase; aPKC; atypical protein kinase C; Cho; cholesterol; EC; (−)-epicatechin; EDTA; ethylenediaminetetraacetic acid; NEFA; non-esterified fatty acids; PFA; paraformaldehyde; PKC; protein kinase C; PMS

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Nck1 deficiency improves pancreatic β cell survival to diabetes-relevant stresses by modulating PERK activation and signaling

Keywords: آکت; Pancreatic β cell survival; Nck1; PERK; Autophagy; Nrf2; Akt;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

CB1 cannabinoid receptor antagonist attenuates left ventricular hypertrophy and Akt-mediated cardiac fibrosis in experimental uremia

Keywords: آکت; α-SMA; α-smooth muscle actin; ANP; atrial natriuretic peptide; β-MHC; myosin heavy chain beta; BNP; brain natriuretic peptide; BW; body weight; CB1R; cannabinoid receptor type 1; CKD; chronic kidney disease; CMR; cardiac magnetic resonance; CVD; cardio

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

EGF stimulates the activation of EGF receptors and the selective activation of major signaling pathways during mitosis

Keywords: آکت; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; PLC-γ1; phospholipase C-γ1; PI3K; phosphoinositide 3-kinase; GAP; GTPase-activating protein; ERKs; extracellular signal-regulated kinases; MEK; mitogen-activated protein kinase kinase

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Effects of chronic cerebral hypoperfusion and low-dose progesterone treatment on apoptotic processes, expression and subcellular localization of key elements within Akt and Erk signaling pathways in rat hippocampus

Keywords: آکت; 2VO; bilateral common carotid artery occlusion; Akt; protein kinase B; Casp 3; caspase 3; CCH; chronic cerebral hypoperfusion; Cyt C; cytochrome c; EDTA; ethylenediaminetetraacetic acid; EGTA; ethylene glycol tetraacetic acid; EPM; elevated plus maze; Erk

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Ink4/Arf locus restores glucose tolerance and insulin sensitivity by reducing hepatic steatosis and inflammation in mice with impaired IRS2-dependent signalling

Keywords: آکت; T2DM; type 2 diabetes mellitus; AKT; V-akt murine thymomaviral oncogene homolog kinase; AUC; area under the curve; SAPK/JNK; stress-activated protein kinase/c-Jun N-terminal kinases; IRS2; insulin receptor substrate 2; BW; body weight; CDK; cyclin-depende

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Dual role of Src kinase in governing neuronal survival

Keywords: آکت; Src kinase; Excitotoxicity; NMDA receptor; Calpain; Akt

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

NDRG2 promotes myoblast proliferation and caspase 3/7 activities during differentiation, and attenuates hydrogen peroxide - But not palmitate-induced toxicity

Keywords: آکت; NDRG2; N-myc downstream-regulated gene 2; MRFs; myogenic regulatory factors; Cdk; cyclin-dependent kinase; Rb; retinoblastoma; Myf5; myogenic factor 5; MyoD; myogenic differentiation; p27; p27 kip1; p21; p21 waf1/cip1; Akt; thymoma viral proto-oncogene; P

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme

Keywords: آکت; PDK1 inhibitors; Kinase inhibitors; Oxindole derivatives; Glioblastoma; GBM stem cells; Multi-target therapy; PI3K; phosphatidylinositol-3-kinase; PDK1; phosphoinositide-dependent kinase-1; GSK3; Glycogen synthase kinase 3; CHK1; Checkpoint kinase-1; Akt;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

P2Y1 receptor mediated neuronal fibre outgrowth in organotypic brain slice co-cultures

Keywords: آکت; Purinergic stimulation; P2Y1 receptors; Organotypic slice co-culture; Dopaminergic system; Fiber growth; PI3K/Akt; ERK1/2; ACSF; artificial cerebrospinal fluid; ADPβS; adenosine-5′-O-(2-thiodiphosphate); Akt; serine-threonine kinase Akt; ANOVA; analy

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

MET Suppresses Epithelial VEGFR2 via Intracrine VEGF-induced Endoplasmic Reticulum-associated Degradation

Keywords: آکت; HGF; VEGF; ERAD; PI3 kinase; AKT; MEK; IRE1; XBP1

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

The mesmiRizing complexity of microRNAs for striated muscle tissue engineering

Keywords: آکت; ACS; acute coronary syndrome; Ago-2; Argonaute 2; Akt; protein kinase B; AMI; acute myocardial infarction; anti-miR; antagomiRs against microRNA; Bcl-2; B cell leukemia/lymphoma 2; CAD; coronary artery disease; Camk-IIγ; calcium/calmodulin-dependent prot

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2015 سفارش ترجمه

Physiology and pathophysiology of IGFBP-1 and IGFBP-2 – Consensus and dissent on metabolic control and malignant potential

Keywords: آکت; IGFBP-1; IGFBP-2; metabolism; diabetes; obesity; cancer; AKT; PTEN; steroids

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2015 سفارش ترجمه

Differential contribution of key metabolic substrates and cellular oxygen in HIF signalling

Keywords: آکت; ACC; acetyl-CoA carboxylase; Akt; protein kinase B (PKB); α-KG; α-ketoglutarate; AMPK; AMP-activated protein kinase; BPTES; (bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sulfide; DIC; differential interference contrast; DMEM; Dulbecco׳s Modifie

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2015 سفارش ترجمه

Methylseleninic acid promotes antitumour effects via nuclear FOXO3a translocation through Akt inhibition

Keywords: آکت; Methylseleninic acid (PubChem CID: 161597); Sodium selenite (PubChem CID: 24934); Cisplatin (PubChem CID: 441203); LY294002 (PubChem CID: 3973); MSA; methylseleninic acid; Se; selenium; PPP; pentose phosphate pathway; TCA; tricarboxylic acid; ROS; reactiv

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2015 سفارش ترجمه

Bioactivity-integrated UPLC/Q-TOF-MS of Danhong injection to identify NF-κB inhibitors and anti-inflammatory targets based on endothelial cell culture and network pharmacology

Keywords: آکت; Akt; protein kinase B; ANAVO; analysis of variance; Bax; Bcl-2 associated X protein; Bcl-2; B-cell lymphoma-2; BCR; B cells receptors; CA; caffeic acid; CAD; coronary artery disease; CHM; Chinese herbal medicines; DEX; dexamethasone; DHI; Danhong injectio

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2015 سفارش ترجمه

Wnt5a and Wnt11 inhibit the canonical Wnt pathway and promote cardiac progenitor development via the Caspase-dependent degradation of AKT

Keywords: آکت; Wnt signaling; β-Catenin; Caspase; Akt; Heart; Cardiac progenitor cell;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2015 سفارش ترجمه

Associate editor: B. TeicherTargeting the genetic alterations of the PI3K-AKT-mTOR pathway: Its potential use in the treatment of bladder cancers

Keywords: آکت; Urothelial bladder cancer; PI3K; AKT; PTEN; mTOR; TSC1; AMPK; AMP-activated protein kinase; Bad; B cell leukemia/lymphoma-2 associated death agonist; Bcl-2; B cell leukemia-2; Bim; B cell leukemia/lymphoma-2 interacting mediator of cell death; CREB; cycli

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2015 سفارش ترجمه

Liposomal short-chain C6 ceramide induces potent anti-osteosarcoma activity in vitro and in vivo

Keywords: آکت; Osteosarcoma; Liposomal C6 ceramide; Apoptosis; Akt; Methotrexate and chemo-sensitization;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2015 سفارش ترجمه

Inhibition of SH2-domain-containing inositol 5-phosphatase (SHIP2) ameliorates palmitate induced-apoptosis through regulating Akt/FOXO1 pathway and ROS production in HepG2 cells

Keywords: آکت; Lipoapoptosis; SHIP2; Palmitate; ROS; Akt; FOXO-1; Liver; HepG2; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2015 سفارش ترجمه