Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme

Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Medicinal Chemistry - Volume 105, 13 November 2015, Pages 274-288

Simona Sestito, Giulia Nesi, Simona Daniele, Alma Martelli, Maria Digiacomo, Alice Borghini, Daniele Pietra, Vincenzo Calderone, Annalina Lapucci, Marco Falasca, Paola Parrella, Angelantonio Notarangelo, Maria C. Breschi, Marco Macchia, Claudia Martini,