Keywords: 2,5-DXP; 2,5-diketopiperazine; ACC; adenoid cystic carcinomas; BBR; berberine; BET; bromodomain and extraterminal; CA; chebulagic acid; CPT; camptothecin; EMT; epithelial-mesenchymal transition; GSK3; glycogen synthase kinase 3-; HCC; hepatocellular carci
مقالات ISI (ترجمه نشده)
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Keywords: AGE; advanced glycation end products; AICAR; 5-Aminoimidazole-4-carboxamide ribonucleotide; AMPK; 5â² adenosine monophosphate-activated protein kinase; APC; antigen-presenting cell; Atg7; autophagy-related gene 7; ATP; adenosine triphosphate; ATRA; all-t
Keywords: Aβ; amyloid beta; AMPAR; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; AD; Alzheimer's disease; APP; amyloid precursor protein; Arc; activity-regulated cytoskeleton-associated protein; BDNF; brain-derived neurotrophic factor; AFM; ato
Keywords: AD; Alzheimer's disease; PPs; polyphenols; EGCG; epigallocatechin gallate; NFTs; neurofibrillary tangles; ACh; acetylcholine; Aβ; amyloid-beta; APP; amyloid precursor protein; PS-1; presenilin-1; PS-2; presenilin-2; AChE; acetylcholine esterase; Cdk5;
Keywords: Neurodegeneration; Insulin signaling; Triiodothyronine; Diabetes; Hippocampus; Tau protein; GSK3;
Keywords: Cerebellar granule neurons; Migration; Leading process; Axon; Microtubules; Glycogen synthase kinase-3; CGN; cerebellar granule neuron; EGL; external granule layer; IGL; internal granule layer; ML; molecular layer; CNS; central nervous system; DIV; days i
Keywords: AD; Alzheimer's disease; APP; amyloid precursor protein; ApoE; apolipoprotein E; CNS; central nervous system; degu; Octodon degus; GFAP; glial fibrillary acidic protein; GSK3; glycogen synthase kinase 3; NCBI; National Centre for Biotechnology Information
Keywords: CREB; cAMP responsive element binding protein; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GSK3; glycogen synthase kinase type 3; H2; molecular hydrogen; H2O2; hydrogen peroxide; IL-1β; interleukin-1β; IL-6; interleukin-6; NF-kB; nuclear factor tra
Keywords: Phenotype switching; Melanoma; Cancer-associated fibroblasts; Drug resistance; Tumor-stroma interactions; CAF; Cancer associated fibroblasts; CDSS; Cancer drug sensitivity screening; EMT; Epithelial-to-mesenchymal transition; FACS; Fluorescence-activated
Keywords: Alzheimer's disease; Heavy metals; Berberine; Amyloid-β40/42; Tau protein; Proinflammatory cytokines and In silico analysis; AChE; acetylcholinesterase; AD; Alzheimer's disease; Akt; Protein kinase B; AMPK; 5Ⲡadenosine monophosphate-activated protein
Keywords: ASPS; advanced sleep phase syndrome; AUD; alcohol use disorder; BDZ; benzodiazepine; CK1; casein kinase 1; CD; circadian desynchrony; CRSDs; circadian rhythm sleep disorders; DSPS; delayed sleep phase disorder; DA; dopamine; DARPP32; dopamine- and cAMP-re
Keywords: AA; amino acid; Aβo; oligomeric β-amyloid; Aβ; β-amyloid; AD; Alzheimer's disease; α7nAChR; α7 nicotinic acetylcholine receptor; ALS; amyotrophic lateral sclerosis; APLP1; amyloid beta precursor-like protein 1; APP; amyloid precursor protein; β-A
Keywords: Liver; RAGE; AKT; GSK3; NRF2; AGEs; Advanced glycation end products; RAGE; receptor for advanced glycation end products; ROS; reactive oxygen species; Nfkb1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1; PI3K; phosphoinositide 3-ki
Keywords: APC; adenomatous polyposis coli gene; CK1; casein kinase 1; DTF; desmoid-type fibromatosis; ECM; extracellular matrix; FAP; familial adenomatous polyposis; Fap-1α; fibroblast activation protein 1α; GSK3; glycogen synthase kinase 3; MRI; magnetic resona
Keywords: KME; aqueous extract of Korean mistletoe; EMG; electromyography; FoxO1; forkhead box protein O1; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; GSK3; glycogen synthase kinase 3; IGF; insulin growth factor; IR; insulin receptor; IRS1; insulin receptor su
Keywords: ACCORD-MIND; Action to Control Cardiovascular Risk in Diabetes-Memory in Diabetes; BBB; blood-brain barrier; BD; bipolar disorder; BDNF; brain-derived neurotrophic factor; DISC1; disrupted in schizophrenia 1; GLUT; glucose transporter; GSK3; glycogen sy
Keywords: Oxysterols; Survival; Nrf2; Autophagy; 5,6-S; 5,6-secosterol; 24OH; 24-hydroxycholesterol; 25OH; 25-hydroxycholesterol; 27OH; 27-hydroxycholesterol; 7K; 7-ketocholesterol; 7βOH; 7β-hydroxycholesterol; AGE; advanced glycation end products; AMPK; AMP-acti
Keywords: NDDs; neurodevelopmental disorders; PA; perinatal asphyxia; GFAP; glial fibrillary acidic protein; MAP-2; Microtubule associate protein-2; NF H/Mp; phosphorylated high and medium molecular weight neurofilaments; NeuN; neuron-specific nuclear protein; OF;
Keywords: Stem/progenitor cells; Sp1; P2X7 receptors; P2Y13 receptors; GSK3; Nrf-2; DUSP; MAPK signaling; (AIS); axon initial segment; (ATF3); activating transcription factor 3; (BBG); Brilliant Blue G; (BDNF); brain-derived neurotrophic factor; (bFGF); basic fibro
Keywords: BBB; blood-brain barrier; Bcl-2; B-cell lymphoma 2; Cdk5; cyclin-dependent kinase 5; DCX; doublecortin; GSK3; glycogen synthase kinase 3; MCAO; middle cerebral artery occlusion/reperfusion; NF-κB; nuclear factor-kappa B; SalA; salvianolic acid A; β-cate
Keywords: Blood-brain barrier; Neurovascular unit; Glycolysis; Lactate; Brain development; AGEs; advanced glycation end products; ADP; ribose-adenosine diphosphate ribose; ATP; adenosine triphosphate; BBB; blood-brain barrier; BDNF; brain-derived growth factor; C
Keywords: ACE; angiotensin converting enzyme; Akt; protein kinase B; DBP; diastolic blood pressure; GSK3; glycogen synthase kinase 3; HDL-C; high-density-lipoprotein cholesterol; HMGCoA; 3-hydroxy-3-methylglutaryl coenzyme A; LDL-C; low-density-lipoprotein choleste
Keywords: AC; adenylyl cyclase; AKT; protein kinase B; AMPK; AMP-activated protein kinase; AnR; androgen receptor; ARF6; ADP ribosylation factor 6; CaMK; Ca2+-calmodulin dependent kinase; CaMKK; CaMK kinase; cAMP; cyclic adenosine 3â²,5â²-monophosphate; CDK5; cyc
Keywords: AMP; adenosine monophosphate; FBPase; fructose-1,6-bisphosphatase; FBP1; liver FBPase; FBP2; muscle FBPase; F1,6P2; fructose-1,6-bisphosphate; F6P; fructose-6-phosphate; FITC; fluorescein isothiocyanate; GSK3; glycogen synthase kinase 3; WT; wildtype; Fru
Keywords: Neurotrophins; Signalling endosome; Endosome acidification; Trk receptors; Membrane motility; Receptor internalization; AP-2; adaptor protein complex 2; BDNF; brain-derived neurotrophic factor; CREB; cAMP response element-binding protein; EEA1; early endo
Keywords: AD; Alzheimer's disease; Aβ; amyloid beta; CDK5; cyclin-dependent kinase 5; CNS; central nervous system; COX; cyclooxygenase; CRP; C-reactive protein; FADD; Fas-Associated protein with Death Domain; GSK3; glycogen synthase kinase-3; IFN-γ; interferon-γ
Keywords: Atoh1; Atonal homolog 1; MC; mucinous colon cancer; SRCC; signet ring cell carcinoma; GSK3; glycogen synthase kinase 3; Lgr5; Leucine-rich repeat-containing G-protein coupled receptor 5; IEC; intestinal epithelial cells; MUC2; mucin 2; TFF3; trefoil facto
Keywords: Pyridazinone; Phthalazinone; Kinases; Docking; GSK3;
Keywords: BMPs; Bone morphogenetic proteins; CMs; Cardiomyocytes; CPCs; Cardiac progenitor cells; CPVT; Catecholamine polymorphic ventricular tachycardia; DMSO; Dimethylsulfoxide; ECs; Endothelial cells; END-2; Endoderm-like cell line; ESCs; Embryonic stem cells; F
Keywords: APC; adenomatosis polyposis coli; C-domain; central domain; CRMP2; collapsin response mediator protein 2; DAPI; 4â²,6-diamidino-2-phenylindole; GSK3; glycogen synthase kinase 3; IC50; half-maximal inhibitory concentration; MAP1B; microtubule-associated p
Keywords: ERK; extracellular signal regulated protein kinase; FoxO1/3; forkhead family transcription factor; GSK3; glycogen synthase kinase-3; HIF; hypoxia-inducible factor; IGF; insulin-like growth factor; IRE1; inositol-requiring protein 1; JNK; c-Jun N-terminal
Keywords: BDNF; brain-derived neurotrophic factor; GCL; granule cell layer; GSK3; glycogen synthase kinase 3; NGS; normal goat serum; NIH; novelty-induced hypophagia; qRT-PCR; Quantitative Real Time-PCR; SGZ; subgranular zone; VEGF; vascular endothelial growth fact
Keywords: ECM; extracellular matrix; NF-κB; nuclear factor kappa B; Akt; protein kinase B; tPA; tissue plasminogen activator; TSRs; thrombospondin type 1 repeats; PDGF; platelet-derived growth factor; PCR; polymerase chain reaction; MCA; middle cerebral artery; CB
Keywords: ARE; antioxidant response element; ATP; adenosine triphosphate; BDNF; brain-derived neurotrophic factor; CAT; catalase; COX; cyclooxygenase; CREB; cAMP-response element-binding-protein (CREB); DNA; deoxyribonucleic acid; EFE; ethyl ferulate (ethyl 4-hydro
Keywords: Inositol; Insulin resistance; Diabetes; Polycystic ovary syndrome; Metabolic syndrome; Diabetic neuropathy; AC; adenylyl cyclase; ACC; acetyl-coenzyme A carboxylase; AGEs; advanced glycation end products; AMP; adenosine monophosphate; cAMP; cyclic AMP; AM
Crystal structure of GSK3β in complex with the flavonoid, morin
Keywords: GSK3; Morin; Alzheimer's disease; Complex structure; Natural compound;
Exercising with blocked muscle glycogenolysis: Adaptation in the McArdle mouse
Keywords: Insulin receptor; AMPK; Glycogen; McArdle mouse; AMPK; 5â² adenosine monophosphate-activated protein kinase; CaMKII; Ca2Â +/calmodulin-dependent protein kinase II; EDL; Extensor digitorum longus; GLUT4; Glucose transporter 4; GS; Glycogen synthase; GSK3;
Baicalin exerts neuroprotective effects via inhibiting activation of GSK3β/NF-κB/NLRP3 signal pathway in a rat model of depression
Keywords: MDD; major depressive disorder; HPA; Hypothalamus-Pituitary-Adrenal; CNS; central nervous system; NSCs; neural stem cells; DG; dentate gyrus; CUMS; chronic unpredictable mild stress; BA; Baicalin; SPT; sucrose preference test; FST; forced swimming test; O
Diphenyl diselenide regulates Nrf2/Keap-1 signaling pathway and counteracts hepatic oxidative stress induced by bisphenol A in male mice
Keywords: BPA; bisphenol A; PhSe2; diphenyl diselenide; Nrf2; nuclear factor (erythroid-derived 2)-like 2; Keap1; Kelch-like ECH-associated protein 1; i.g; intragastric;; EDCs; endocrine disrupting chemicals; NPSH; non-protein thiol; PND; postnatal day; δALA-D; δ
Enhanced Repair of UV-Induced DNA Damage by 1,25-Dihydroxyvitamin D3 in Skin Is Linked to Pathways that Control Cellular Energy
Keywords: 1,25(OH)2D3; 1α,25-dihydroxyvitamin D3; 2-dG; 2-deoxy-d-glucose; 8-oxo-dG; 8-oxo-2â²-deoxyguanosine; Akt; acutely transforming retrovirus AKT8 in rodent T-cell lymphoma; CPD; cyclobutane pyrimidine dimer; ÎÏm; mitochondrial membrane potential; ECAR; e
Treatment of Dendropanax morbifera leaves extract improves diabetic phenotype and inhibits diabetes induced retinal degeneration in db/db mice
Keywords: Dendropanax morbifera; Type 2 diabetes mellitus; Retinal degeneration; Db/db mice; Glucose transporter; AMP-activated protein kinase; DLE; Dendropanax morbifera leaves extract; IGT; Impaired glucose tolerance; GK; glucokinase; PEPCK; phosphoenolpyruvate c
The amyloid precursor protein binds to β-catenin and modulates its cellular distribution
Keywords: APP; amyloid precursor protein; BACE; beta-APP cleaving enzyme; GSK3; Glycogen Synthase Kinase 3; PCP; planar cell polarity; TCF/LEF; T-cell factor/lymphoid enhancer factor; TopFlash; TCL/LEF-Firefly luciferase; Alzheimer's disease; β-catenin; Amyloid
The Dictyostelium GSK3 kinase GlkA coordinates signal relay and chemotaxis in response to growth conditions
Keywords: GlkA; glycogen synthase kinase-like kinase A; PI(3,4,5)P3; phosphatidylinositol (3,4,5)-triphosphate; MyoII; Myosin II; AL; activation loop; HM; hydrophobic motif; RBD; Ras binding domain; iTRAQ; isobaric tags for relative and absolute quantification; DIA
Ubiquitin-proteasome signaling in lung injury
Keywords: AJ; adherens junctions; ALI; acute lung injury; AMPK; adnosine monophosphate activated protein kinase; ARDS; acute respiratory distress syndrome; ATP; adenosine triphosphate; CFTR; cystic fibrosis transmembrane conductance regulator; cIAP; cellular inhibi
TNFα disrupts blood brain barrier integrity to maintain prolonged depressive-like behavior in mice
Keywords: Blood brain barrier; Depression recovery; GSK3; Learned helplessness; Neuroinflammation; TNFα;
Liver carbohydrates metabolism: A new islet-neogenesis associated protein peptide (INGAP-PP) target
Keywords: GK; Glucokinase; G-6-Pase; glucose-6-phosphatase; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; GSK3; glycogen synthase kinase-3β; HIS; hepatic insulin sensitivity; HOMA-IR; homeostasis model assessment; INGAP-PP; islet-neogenesis associated protein p
Structure-based design of novel quinoxaline-2-carboxylic acids and analogues as Pim-1 inhibitors
Keywords: Quinoxaline; Pim-1; Kinase inhibitor; Anticancer targeted therapy; IC50; 50% inhibitory concentration; SAR; structure-activity relationships; Pim; proviral integration site of Moloney murine leukemia virus; CML; chronic myeloid leukemia; DYRK1A; dual spec
A partnership with the proteasome; the destructive nature of GSK3
Keywords: AMPK; AMP-activated protein kinase; ARE; antioxidant response element; β-TrCP; beta-transducin repeat containing protein; CKI; casein kinase-1; CHD; chromatin helicase DNA-binding factor; CRY; cryptochrome; EMT; epithelial-mesenchymal transition; FGD; fa
Neuroprotective effects of valproic acid on brain ischemia are related to its HDAC and GSK3 inhibitions
Keywords: Valproic acid; Neuroprotection; Inflammation; Oxidative stress; HDAC; GSK3;
New mechanism underlying IL-31-induced atopic dermatitis
Keywords: Atopic dermatitis; pruritogens; brain-derived natriuretic peptide; pruritus; skin; dorsal root ganglion; keratinocytes; dendritic cells; soluble N-ethylmaleimide-sensitive factor activating protein receptors; AD; Atopic dermatitis; BNP; Brain-derived na