دانلود مقالات ISI درباره Gsk3 + ترجمه فارسی

Wnt signaling in adult intestinal stem cells and cancer

Keywords: APC; Adenomatous Polyposis Coli; Axin; axis inhibition protein; β-TrCP; beta-transducin repeat containing protein; BMP; bone morphogenic protein; CBC; crypt base columnar; CRC; colorectal carcinoma; CSCs; cancer stem cells; Dkk; Dickkopf; FAP; Familial A

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Protein kinase-D1 overexpression prevents lipid-induced cardiac insulin resistance

Keywords: AMPK; AMP-activated protein kinase; AW; anterior wall; BNP; B-type natriuretic peptide; caPKD1; cardiospecific constitutively active PKD1 overexpression; DAG; diacylglycerol; EFS; electric field stimulation; [18F]FDG; [18F]fluoro-deoxyglucose; [18F]FTHA;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Crosstalk between tyrosine kinase receptors, GSK3 and BMP2 signaling during osteoblastic differentiation of human mesenchymal stem cells

Keywords: BMPs; bone morphogenic proteins; TGF-β; transforming growth factor beta; MSC; mesenchymal stem cell; PDGF; platelet derived growth factor; FGF; fibroblast growth factor; EGF; epidermal growth factor; RTK; receptors tyrosine kinase; HMSC; human MSC; ALP;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

C-Src-mediated phosphorylation of δ-catenin increases its protein stability and the ability of inducing nuclear distribution of β-catenin

Keywords: δ-Catenin; c-Src; Tyrosine phosphorylation; GSK3; E-cadherin;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

New insights into Notch1 regulation of the PI3K-AKT-mTOR1 signaling axis: Targeted therapy of γ-secretase inhibitor resistant T-cell acute lymphoblastic leukemia

Keywords: ADAM; a disintegrin and metalloprotease; AICAR; 5-aminoimidazole-4-carboxamide ribonucleotide; AKT; protein kinase B (PKB); ALL; acute lymphoblastic leukemia; AML; acute myeloid leukemia; AMPK; adenosine monophosphate (AMP) activated protein kinase; ANK;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Oral administration of soybean peptide Vglycin normalizes fasting glucose and restores impaired pancreatic function in Type 2 diabetic Wistar rats

Keywords: Saline group; HFD/saline group; STZ group; HFD/STZ/saline group; Low group; HFD/STZ/Vglycin 40 μg/[g·d]; High group; HFD/STZ/Vglycin 80 μg/[g·d] group; Met group; HFD/STZ/Met; p-Akt; phosphorylated Akt; C-PARP; cleaved PARP; GSK3; Glycogen Synthase Ki

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2014 سفارش ترجمه

Small molecule modulators of Wnt/β-catenin signaling

Keywords: APC; adenomatous polyposis coli; CRC; colorectal cancer; Dvl; dishevelled; LEF/TCF; lymphoid enhancer factor/T cell factor; Fzd1; Frizzled1; GFP; green fluorescent protein; GSK3; glycogen synthase kinase 3; SAR; structure-activity relationships; Wnt sig

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Transglutaminase 2 as a novel activator of LRP6/β-catenin signaling

Keywords: Fzd; Frizzled; LRP5/6; LRP5 or LRP6; APC; Adenomatosis Polyposis Coli; GSK3; Glycogen Synthase Kinase 3; TG2; Tissue transglutaminase; VSMCs; Vascular smooth muscle cells; TGases; Transglutaminases; ECM; Extracellular matrix; MEFs; Mouse embryonic fibrobl

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Regulatory mechanisms for glycogenolysis and K+ uptake in brain astrocytes

Keywords: AE; anion exchanger; AMPK; AMP-activated protein kinase; CA; carbonic anhydrase; CTS; cardiotonic steroids; DAB; 1,4-dideoxy-1,4-imino-d-arabinitol; DIDS; 4,4′-diisothiocyanostilbene-2,2′-disulfonic acid; EGFR; epidermal growth factor receptor; ERK; e

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Destabilization of fructose 1,6-bisphosphatase-Z-line interactions is a mechanism of glyconeogenesis down-regulation in vivo

Keywords: FBPase; Glyconeogenesis; GSK3; Insulin; Striated muscle;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Chibby drives β catenin cytoplasmic accumulation leading to activation of the unfolded protein response in BCR-ABL1 + cells

Keywords: CML; chronic myeloid leukemia; TK; tyrosine kinase; LSC; leukemic stem cell; APC; Adenomatous polyposis coli; GSK3; glycogen synthase kinase 3; CBY; Chibby; TCF; T cell factor; LEF; lymphoid enhancer factor; ER; endoplasmic reticulum; UPR; unfolded protei

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Therapeutic concentrations of valproate but not amitriptyline increase neuropeptide Y (NPY) expression in the human SH-SY5Y neuroblastoma cell line

Keywords: AMI; amitriptyline; AP-1; activator protein 1; Atoh1; atonal homolog-1; BDNF; brain-derived neurotrophic factor; bp; base pair; CREB; cAMP response element-binding protein; Cp; crossing point; ERK; extracellular signal-regulated kinase; DMEM/F12 Ham; Dulb

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

The conserved role of the AKT/GSK3 axis in cell survival and glycogen metabolism in Rhipicephalus (Boophilus) microplus embryo tick cell line BME26

Keywords: 10-DEBC; 10-(4′-(N,N-Diethylamino) butyl)-2-chlorophenoxazine hydrochloride; AKT; Protein kinase B; CN; Negative control; DMSO; Dimethyl sulfoxide; dsRNA; Double-stranded RNA; dsCN; Unrelated dsRNA; dsAKT; Double-stranded RNA for protein kinase B; dsGSK

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

TCDD induces the expression of insulin-like growth factor binding protein 4 in 5L rat hepatoma cells: A cautionary tale of the use of this cell line in studies on dioxin toxicity

Keywords: AhR; aryl hydrocarbon receptor; AKT1S1; proline-rich AKT1 substrate 1; CYP1A1; cytochrome P450 1A1; 4E-BP1; eukaryotic translation initiation factor 4E-binding protein 1; ERK; extracellular signal-regulated protein kinase; GSK3; glycogen synthase kinase 3

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Glycogen synthase kinase 3 regulates expression of nuclear factor-erythroid-2 related transcription factor-1 (Nrf1) and inhibits pro-survival function of Nrf1

Keywords: ARE; antioxidant response element; CNC-BZIP; Cap 'n' Collar-type basic leucine zipper; CPD; Cdc4 phosphodegron domain; ER; endoplasmic reticulum; GSK3; glycogen synthase kinase 3; Nrf1; nuclear factor E2-related factor-1; SCF; Skp1-Cul1-F-box; UPS

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Effects of the Ras homolog Rhes on Akt/protein kinase B and glycogen synthase kinase 3 phosphorylation in striatum

Keywords: GPCR; G protein-coupled receptor; GSK3; glycogen synthase kinase-3; LiCl; lithium chloride; PKA; protein kinase A; TMR; transmembrane receptors; PP2A; protein phosphatase 2A; Rhes; Ras Homolog Enriched in Striatum; dopamine; lithium; G protein; striatum;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Tau protein phosphatases in Alzheimer's disease: The leading role of PP2A

Keywords: AD; Alzheimer's disease; NFT; neurofibrillary tangles; PHF; paired helical filaments; SP; senile plaques; APP; apolipoprotein; PP1; protein phosphatase-1; PP2A; protein phosphatase-2A; PP2B; protein phosphatase-2B; PP5; protein phosphatase-5; PTEN; phosph

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Wnt signaling inhibits CTL memory programming

Keywords: T cells; Cytotoxicity; Wnt; GSK3; Cytokines; Memory; mTOR; Rapamycin;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Wnt/β-catenin signaling activates bone morphogenetic protein 2 expression in osteoblasts

Keywords: ALP; alkaline phosphatase; BGJ medium; Biggers, Gwatkin, and Judah medium; BMP; bone morphogenetic protein; β-TrCP; β-transducin repeat-containing protein; Col1a1; type I collagen 1a1; CTGF; connective-tissue growth factor; CREB; cAMP responsive element

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Lithium enhances CRTC oligomer formation and the interaction between the CREB coactivators CRTC and CBP - Implications for CREB-dependent gene transcription

Keywords: BDNF; brain derived neurotrophic factor; bZip; basic region-leucine zipper; CBP; CREB-binding protein; ChIP; chromatin immunoprecipitation; CRE; cAMP-response element; CREB; cAMP-response element binding protein; CRTC; cAMP-regulated transcriptional coact

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Neuroscience Forefront ReviewProneural genes in neocortical development

Keywords: Ascl1; Achaete scute-like 1; AS-C; achaete-scute complex; BAF; Brahma-associated factors; bHLH; basic-helix-loop-helix; CGE; caudal ganglionic eminences; GABA+; GABAergic; glu+; glutamatergic; GSK3; glycogen synthase kinase 3; Hes1; hairy and enha

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2013 سفارش ترجمه

Tau protein kinases: Involvement in Alzheimer's disease

Keywords: AD; Alzheimer's disease; APP; amyloid precursor protein; Arg; Abl-related gene; SFK; Src family kinase; Aβ; β-amyloid; BBB; blood brain barrier; LD50; lethal dose 50; c-Abl; c-Abelson; Cables; c-Abl-binding adaptator protein; CaMKII; Ca2+/calmodulin-dep

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2013 سفارش ترجمه

The sources of salidroside and its targeting for multiple chronic diseases

Keywords: 6-OHDA; 6-hydroxydopamine; Aβ; β-amyloid protein; MPTP; 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine; MPP+; N-methyl-4-phenylpyridine; AD; Alzheimer's disease; PD; Parkinson's disease; STZ; streptozotocin; PI3K; phosphatidylinositol 3-kinase; ROS; react

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2020 سفارش ترجمه

Single prolonged stress enhances hippocampal glucocorticoid receptor and phosphorylated protein kinase B levels

Keywords: PTSD; posttraumatic stress disorder; SPS; single prolonged stress; EPM; elevated plus maze; OF; open field; GR; glucocorticoid receptor; Akt; protein kinase B; pAkt; phosphorylated Akt; PI3K; phosphoinositide 3-kinase; mTOR; mammalian target of Rapamycin;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

In vitro mitochondrial failure and oxidative stress mimic biochemical features of Alzheimer disease

Keywords: Sodium azide; Hydrogen peroxide; Tau; GSK3; p35/25; BACE1

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Axonal degeneration in Alzheimer's disease: When signaling abnormalities meet the axonal transport system

Keywords: Alzheimer's disease; Axonal transport; Synapse; Kinase; Phosphatase; Amyloid; Presenilin; Tau; Kinesin; Dynein; Signaling; Amyloid; ApoE; GSK3; CK2

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Anti-HER3 Domain 1 and 3 Antibodies Reduce Tumor Growth by Hindering HER2/HER3 Dimerization and AKT-Induced MDM2, XIAP, and FoxO1 Phosphorylation

Keywords: Ab; antibody; NRG; neuregulin; PBS; phosphate-buffered saline; TR-FRET; time-resolved fluorescence resonance energy transfer; XIAP; X-linked inhibitor of apoptosis; FoxO1; forkhead box O1; MDM2; murine double minute 2; GSK3; glycogen synthase kinase 3;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

Proteasome inhibition-induced p38 MAPK/ERK signaling regulates autophagy and apoptosis through the dual phosphorylation of glycogen synthase kinase 3β

Keywords: GSK3; p70S6K; MAPK; MG132; Autophagy

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Muscle FBPase binds to cardiomyocyte mitochondria under glycogen synthase kinase-3 inhibition or elevation of cellular Ca2+ level

Keywords: FBPase; Mitochondria; GSK3; Calcium; Cardiomyocyte; Hypertrophy

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Functional significance of glycogen synthase kinase-3 regulation by serotonin

Keywords: FST; forced swim test; GSK3; glycogen synthase kinase-3; 5-HT1A; serotonin type 1A receptors; i.p.; intraperitoneal; KI; knock-in; PI3K; phosphoinositide 3-kinase; PKA; protein kinase A; PKC; protein kinase C; WT; wild type; Serotonin; 5-HT1A; Fluoxetine;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Neurodegeneration, Neuroprotection, and Disease-Oriented NeuroscienceResearch PaperSimilar pattern of peripheral neuropathy in mouse models of type 1 diabetes and Alzheimer's disease

Keywords: Alzheimer's disease; amyloid precursor protein; diabetes; insulin signaling; sciatic nerve; diabetic neuropathy; AD; Alzheimer's disease; APP; amyloid precursor protein; Aβ; amyloid β; EDTA; ethylenediaminetetraacetic acid; FL-APP; full-length APP; GSK3

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Identification of the couple GSK3α/c-Myc as a new regulator of hexokinase II in benzo[a]pyrene-induced apoptosis

Keywords: GSK3; Hexokinase II; c-Myc; Apoptosis; Mitochondria; Benzo[a]pyrene; NHE1;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Brassinosteroids inhibit in vitro angiogenesis in human endothelial cells

Keywords: Angiogenesis; Human umbilical vein endothelial cells; Migration; Natural products; Receptors; AR; androgen receptor; BES1; BRI1 EMS Suppressor 1; BIN2; Brassinosteroid-Insensitive 2; BRI1; Brassinosteroid-Insensitive 1; BRs; brassinosteroids; DMSO; dimeth

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Inhibition of GSK3 attenuates amphetamine-induced hyperactivity and sensitization in the mouse

Keywords: GSK3; Amphetamine; Hyperactivity; Sensitization

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

The role of pseudokinases in cancer

Keywords: ALL; Acute Lymphoblastic Leukaemia; AML; Acute Myeloid Leukaemia; AMPK; 5′-Adenosine Monophosphate Activated Protein Kinase; ATF4; Activating Transcriptional Factor 4; ATP; Adenosine-5′-Triphosphate; BTICs; Brain Tumour-Initiating Cells; C/EBPα; CCAA

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Wnt6, Wnt10a and Wnt10b inhibit adipogenesis and stimulate osteoblastogenesis through a β-catenin-dependent mechanism

Keywords: MSC; mesenchymal stem cell; PPARγ; peroxisome proliferator-activated receptor-γ; FABP4; fatty acid-binding protein 4; C/EBPα; CCAAT/enhancer-binding protein-α; WAT; white adipose tissue; BAT; brown adipose tissue; Id2; inhibitor of DNA binding 2; TLE3

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

ReviewCadherins and neuropsychiatric disorders

Keywords: Brain development; Neural circuit; Synaptic function; Cadherin; Catenin; Wnts; GSK3; Lithium; Disc1; Genetic Linkage; Genome-wide association study; Autism; Schizophrenia; Bipolar disorder; Epilepsy; Cognitive impairment; Addiction; Alcoholism;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2012 سفارش ترجمه

Synthesis of GSK3β mimetic inhibitors of Akt featuring a novel extended dipeptide surrogate

Keywords: Akt; GSK3; Peptidomimetics; Protein–protein interactions; β Strand

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Inhibition of neuronal calcium oscillations by cell surface APP phosphorylated on T668

Keywords: Alzheimer disease; Cultured rat cortical neurons; Calcium oscillations; T668; Phosphorylation; JNK; GSK3; CDK5; Trafficking

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

LKB1 regulates development and the stress response in Dictyostelium

Keywords: LKB1; GSK3; Development; Stress

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Valproate reduces tau phosphorylation via cyclin-dependent kinase 5 and glycogen synthase kinase 3 signaling pathways

Keywords: Alzheimer's disease; Tau; CDK5; GSK3; APP/PS1 transgenic mouse; Valproate; Okadaic acid

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Novel insights for the treatment of Alzheimer's disease

Keywords: 5-HT; 5-hydroxytryptamine (serotonin); Aβ; beta amyloid peptide; AD; Alzheimer's disease; APP; amyloid precursor protein; BDNF; brain-derived neurotrophic factor; cDNA; complementary deoxyribonucleic acid; CoQ10; coenzyme Q10 (ubiquinone); GSK3; glycog

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

The 14-3-3 proteins in regulation of cellular metabolism

Keywords: 4E-BP1; eIF4E-binding protein 1; AANAT; arylalkylamine N-acetyltransferase; ACC; acetyl-CoA carboxylase; AKT; protein kinase B; AMPK; AMP dependent protein kinase; AS; ATP synthase; AS160; AKT substrate 160; ATG; autophagy related; BAD; Bcl-2 antagonist o

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Tau inhibits tubulin oligomerization induced by prion protein

Keywords: AD; Alzheimer disease; CBB; Coomassie brilliant blue; CtmPrP; transmembrane form of prion protein with the C-terminus residing in the lumen of endoplasmic reticulum; cytoPrP; cytosolic prion protein; EDC; 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide; ER;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

β2-Glycoprotein-I based peptide regulate endothelial-cells tissue-factor expression via negative regulation of pGSK3β expression and reduces experimental-antiphospholipid-syndrome

Keywords: Autoimmunity; Antiphospholipid syndrome; Peptide; GSK3; Anti-β2GPI antibodies

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Modulation of human embryonic stem cell-derived cardiomyocyte growth: A testbed for studying human cardiac hypertrophy?

Keywords: ANF; atrial natriuretic factor; bFGF; basic human fibroblast growth factor; CaMK II; Ca2+/calmodulin-dependent kinase II; EB; embryoid body; ERK; extracellular signal-regulated kinases; GSK3; glycogen synthase kinase 3; HDACII; histone deacetylase; FKBP;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Research ArticleGlycogen synthase kinase 3 involvement in the excessive proinflammatory response to LPS in patients with decompensated cirrhosis

Keywords: Cirrhosis; Alcohol; Innate immunity; Lipopolysaccharides; AKT; Glycogen synthase kinase 3; TLR4; Toll-like receptor 4; LPS; lipopolysaccharides; TNF-α; tumor necrosis factor-α; IL; interleukin; GSK3; glycogen synthase kinase 3; PI3K; phosphatidylinosito

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Serine phosphorylation regulates disabled-1 early isoform turnover independently of Reelin

Keywords: ApoER2; apolipoprotein E receptor 2; CsA; cyclosporine A; Cdk; cyclin dependent kinase; Dab1; Disabled-1; CHX; cycloheximide; CPTS; 3,4',4″,4-copper phthalocyanine tetrasulfonic acid, tetrasodium salt; CsA; cyclosporine A; ED; embryonic day; GSK3; glyco

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Mechanisms of antidepressant action: An integrated dopaminergic perspective

Keywords: MDD; Major depressive disorder; DA; dopamine/dopaminergic; NA; noradrenaline; 5-HT; serotonin; 5-HT1A; serotonin receptor 1A; SSRI; selective serotonin reuptake inhibitor; CSF; cerebrospinal fluid; 5-HIAA; 5-Hydroxyindoleacetic acid; NGF; nerve growth fac

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

The role of low-grade inflammation in the polycystic ovary syndrome

Keywords: ADMA; asymmetric dimethylarginine; A-FABP; adipocyte fatty acid-binding protein; AGEs; advanced glycation endproducts; MA; molecular adhesions; Akt/PKB; Akt/protein kinase B; CRP; C reacting protein; ESR; erothrocyte sedimentation rate; ET-1; endothelin-1

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه