دانلود مقالات ISI درباره Gsk3 + ترجمه فارسی

Regulation of nucleocytoplasmic trafficking of viral proteins: An integral role in pathogenesis?

Keywords: BPV; bovine papillomavirus; BRAP2; BRCA1-associated protein 2; CAV; chicken anaemia virus; CBP; CREB binding protein; Cdk; cyclin dependent kinase; CK1; protein kinase CK1; CK2; protein kinase CK2; Crm1; chromosome region maintenance protein 1; CTD; C-ter

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2011 سفارش ترجمه

Associate Editor: V.J. WattsRegulation of stem cell pluripotency and differentiation by G protein coupled receptors

Keywords: G protein coupled receptor; GPCR; Pluripotency; Stem cell; Differentiation; EB; Embryoid body; ES cells; Embyronic stem cells; FZD; Frizzled; GPCRs; G protein coupled receptors; GSK3; Glycogen synthase kinase 3; hATSCs; Human adipose tissue-derived mesenc

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2011 سفارش ترجمه

Synthesis and biological evaluation of new 3-(6-hydroxyindol-2-yl)-5-(Phenyl) pyridine or pyrazine V-Shaped molecules as kinase inhibitors and cytotoxic agents

Keywords: Indole; Pyridine; Pyrazine; CDK; GSK3; DYRK1A; Cytotoxicity; Molecular modeling;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2011 سفارش ترجمه

GSK3: A possible link between beta amyloid peptide and tau protein

Keywords: Alzheimer disease; Beta-amyloid peptide; ApoE4; GSK3; Presenilin; Tau

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

β-Amyloid precursor protein and tau protein levels are differently regulated in human cerebellum compared to brain regions vulnerable to Alzheimer's type neurodegeneration

Keywords: Alzheimer's disease; Amyloid precursor protein; APP; Tau; GSK3; Insulin degrading enzyme

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Changes related to phosphatidylinositol 3-kinase/Akt signaling in leiomyomas: possible involvement of glycogen synthase kinase 3α and cyclin D2 in the pathophysiology

Keywords: Uterine leiomyomas; signal transduction; PI3K/Akt; GSK3; cyclin D2; cell survival

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

CK2 and GSK3 phosphorylation on S29 controls wild-type ATXN3 nuclear uptake

Keywords: ATXN3; Phosphorylation; CK2; GSK3; Subcellular localization; Mass spectrometry

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Tissue selectivity and potential clinical applications of trenbolone (17β-hydroxyestra-4,9,11-trien-3-one): A potent anabolic steroid with reduced androgenic and estrogenic activity

Keywords: 17 β-TBOH; trenbolone; 17 α-TBOH; epitrenbolone; 17β-E2; estradiol; AR; androgen receptor; Akt; serine/threonine-specific kinase family; ACTH; adrenocorticotropic hormone; BMD; bone mineral density; Ca2+; calcium; CSA; cross-sectional area; DHT; dihydr

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2010 سفارش ترجمه

Exogenous insulin stimulates glycogen accumulation in Rhipicephalus (Boophilus) microplus embryo cell line BME26 via PI3K/AKT pathway

Keywords: PI3K; GSK3; BME26 cell line; Signal transduction; Tick; Embryogenesis; Glycogen; Insulin

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Altered growth factor signaling pathways as the basis of aberrant stem cell maturation in schizophrenia

Keywords: ACPT; acid phosphatase, testicular; APC; adenomatous polyposis coli; BCL; B-cell lymphoblastic leukemia; BDNF; brain-derived neurotrophic factor; BMP; bone morphogenic protein; CA; Cornus Ammonis; CDK; cyclin-dependent kinase; CK; casein kinase; CNV; copy

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Phosphatidylinositol-3-Kinase/Akt Signaling Pathway and Kidney Cancer, and the Therapeutic Potential of Phosphatidylinositol-3-Kinase/Akt Inhibitors

Keywords: kidney; carcinoma; renal cell; D 21266; 1-phosphatidylinositol 3-kinase; mTOR protein; 17-HWT; 17-hydroxy-wortmannin; APC; alkylphosphocholine; ERK; extracellular regulated kinase; GSK3; glycogen synthase kinase-3; HIF; hypoxia-inducible factor; IC50; hal

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

XIAP associates with GSK3 and inhibits the promotion of intrinsic apoptotic signaling by GSK3

Keywords: XIAP; GSK3; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Glycogen synthase kinase-3 regulates microglial migration, inflammation, and inflammation-induced neurotoxicity

Keywords: Neuroinflammation; GSK3; Lithium; Cytokine; Lipopolysaccharide; Neuroprotection; Microglia motility

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Regenerative pharmacology in the treatment of genetic diseases: The paradigm of muscular dystrophy

Keywords: MD; muscular dystrophies; DMD; duchenne muscular dystrophy; DAPC; dystrophin-associated protein complex; DGC; dystrophin-glycoprotein complex; DG; dystroglycans; SCG; sarcoglycans; nNOS; neuronal nitric oxide synthase; NO; nitric oxide; HDAC; histone deac

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Elevated glycogen synthase kinase-3 activity in Fragile X mice: Key metabolic regulator with evidence for treatment potential

Keywords: GSK3; Fragile X; Lithium; mGluR; Behavior; Audiogenic seizures

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Cyclic AMP regulates extracellular matrix gene expression and metabolism in cultured primary rat chondrocytes

Keywords: AC; adenylyl cyclase; Act D; actinomycin D; Agc1; aggrecan; ANOVA; analysis of variance; cAMP; cyclic 3′, 5′-adenosine monophosphate; cGK; cyclic guanine monophosphate-dependent protein kinase; Col2a1; type II collagen; Col10a1; type X collagen; CPT-c

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Dopamine D1 receptor activation induces tau phosphorylation via cdk5 and GSK3 signaling pathways

Keywords: Dopamine receptor; Tau; Calcium; cdk5; GSK3; PKA

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Akt regulates skeletal development through GSK3, mTOR, and FoxOs

Keywords: myrAkt, myristoylated Akt; EGFP, enhanced green fluorescence protein; tg(L), transgenic mice with low expression; tg(H), transgenic mice with high expression; FoxO3a-TM, FoxO3a triple mutant; dn, dominant negativeAkt; GSK3; mTOR; FoxO; Chondrocyte maturat

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2009 سفارش ترجمه

The role of glycogen synthase kinase 3 in the early stages of Alzheimers’ disease

Keywords: GSK3; Alzheimer disease; Tau protein

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

HSP105 interacts with GRP78 and GSK3 and promotes ER stress-induced caspase-3 activation

Keywords: HSP105; GRP78; UPR; Apoptosis; GSK3; ER stress;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

Additive effects of histone deacetylase inhibitors and amphetamine on histone H4 acetylation, cAMP responsive element binding protein phosphorylation and ΔFosB expression in the striatum and locomotor sensitization in mice

Keywords: histone deacetylase; cAMP responsive element binding protein; chromatin immunoprecipitation; butyric acid; valproic acid; amphetamine; AcH4; acetylated H4; BA; butyric acid; B+S; butyric acid+saline; ChIP; chromatin immunoprecipitation; co-IP; co-immunopr

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

Unexpectedly robust assembly of the Axin destruction complex regulates Wnt/Wg signaling in Drosophila as revealed by analysis in vivo

Keywords: Wnt signaling; Axin; Mutant analysis; Scaffold; Destruction complex; Complex assembly; In vivo; Drosophila; APC; GSK3; beta-catenin

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2008 سفارش ترجمه

Dual kinase-mediated regulation of PITK by CaMKII and GSK3

Keywords: PITK; PP1; CaMKII; GSK3

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Lithium Regulates Glycogen Synthase Kinase-3β in Human Peripheral Blood Mononuclear Cells: Implication in the Treatment of Bipolar Disorder

Keywords: Bipolar disorder; GSK3; lithium; PBMC

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

GSK-3β regulation in skeletal muscles by adrenaline and insulin: Evidence that PKA and PKB regulate different pools of GSK-3

Keywords: Glycogen synthase kinase; 8-pCPT-2′-O-Me-cAMP; Akt; cAMP; GSK3; AKAP

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Synthesis and structure–activity relationship of 3,4′-bispyridinylethylenes: Discovery of a potent 3-isoquinolinylpyridine inhibitor of protein kinase B (PKB/Akt) for the treatment of cancer

Keywords: Inhibitors of Akt; Akt1; Akt2; Akt3; PKA; PKB; protein kinase B; GSK3; FL5.12-Akt1; X-ray; Anticancer; Apoptosis; Antitumor; Pharmacokinetics; Kinase inhibitors; Structure-based design

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

The role of GSK3 in glucose homeostasis and the development of insulin resistance

Keywords: GSK3; Insulin signaling; Glucose homeostasis

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Identification of potential glycogen kinase-3 inhibitors by structure based virtual screening

Keywords: GSK3; Pharmacophore mapping; Virtual screening; Docking; FlexX;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Tau overexpression in transgenic mice induces glycogen synthase kinase 3β and β-catenin phosphorylation

Keywords: Alzheimer; transgenic; tau; GSK3; Wnt; aa; amino acid; Aβ; amyloid β-protein; AD; Alzheimer's disease; APP; amyloid precursor protein; EM; electron microscopy; GSK3β; glycogen synthase kinase 3β; NFT; neurofibrillary tangle; Non-tg; non-transgenic l

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

3D-QSAR and molecular docking study on bisarylmaleimide series as glycogen synthase kinase 3, cyclin dependent kinase 2 and cyclin dependent kinase 4 inhibitors: An insight into the criteria for selectivity

Keywords: GSK3; CoMFA; QSAR; CDK2; CDK4

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2007 سفارش ترجمه

Molecular connexions between dementia and diabetes

Keywords: Diabetes; Alzheimer's disease; Insulin; GSK3; Insulin-degrading enzyme; PhosphorylationT2DM; Type II diabetes mellitus; AD; Alzheimer's disease; MCI; Mild cognitive impairment; NFT; Neurofibrillary tangle; IR; Insulin receptor; PKB; Protein kinase B; GSK3

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2007 سفارش ترجمه

The role of mitochondria in protection of the heart by preconditioning

Keywords: 5HD; 5-hydroxydecanoate; AMPK; AMP activated protein kinase; ANT; Adenine nucleotide translocase; APD; Action potential duration; BCDH; branched chain 2-oxoacid dehydrogenase; CrK; creatine kinase; CsA; cyclosporin A; CyP; cyclophilin; Cx43; connexin43; G

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2007 سفارش ترجمه

Polymorphisms in the phosphate and tensin homolog gene are not associated with late-onset Alzheimer's disease

Keywords: Late-onset Alzheimer's disease; PTEN; GSK3; Polymorphism; Genetics; DNA pooling;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2006 سفارش ترجمه

Mitotic phosphorylation of tankyrase, a PARP that promotes spindle assembly, by GSK3

Keywords: Tankyrase; GSK3; Mitosis; Phosphorylation; MPM-2; NuMA; Spindle

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Isoquinoline–pyridine-based protein kinase B/Akt antagonists: SAR and in vivo antitumor activity

Keywords: Akt inhibitor; Protein kinase B; PKB; GSK3; FL5.12-Akt; Anticancer

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Discovery and SAR of oxindole–pyridine-based protein kinase B/Akt inhibitors for treating cancers

Keywords: Akt inhibitor; Protein kinase B; PKB; GSK3; FL5.12-Akt; Anticancer

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

PerspectiveCytoskeletal modulators and pleiotropic strategies for Alzheimer drug discovery

Keywords: Tau; Dementia; GSK3; Environmental enrichment; Neurofibrillary tangle;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Discovery of trans-3,4′-bispyridinylethylenes as potent and novel inhibitors of protein kinase B (PKB/Akt) for the treatment of cancer: Synthesis and biological evaluation

Keywords: Akt inhibitors; Akt; PKB; Protein kinase B; GSK3; FL5.12-Akt1; Anticancer; Apoptosis; X-ray

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Phosphorylation of the Pro-X-Thr-Pro site in phosphatase inhibitor-2 by cyclin-dependent protein kinase during M-phase of the cell cycle

Keywords: CDC2; Cyclin B1; GSK3; ERK1/2; MAPK; MEK; Histone H3; Nocodazole; Roscovitine;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

The common inositol-reversible effect of mood stabilizers on neurons does not involve GSK3 inhibition, myo-inositol-1-phosphate synthase or the sodium-dependent myo-inositol transporters

Keywords: Sensory neurons; GSK3; Phosphoinositide signaling; Lithium; Valproate; Carbamazepine; Inositol; Transporters; MIP-synthase

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

AMP-activated protein kinase (AMPK) activating agents cause dephosphorylation of Akt and glycogen synthase kinase-3

Keywords: Akt; Protein kinase B; AMPK; AMP-activated kinase; GSK3; AICAR; Phenformin

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

The neuroprotective agent, valproic acid, regulates the mitogen-activated protein kinase pathway through modulation of protein kinase A signalling in Dictyostelium discoideum

Keywords: cAMP; Dictyostelium; ERK2; GSK3; Lithium; MAP kinase; Neuroprotection; PKA; Signalling; Valproic acidACA, adenylyl cyclase; BSA, bovine serum albumin; cAMP, cyclic AMP; cAR1, cAMP receptor 1; csA, contact sites A; ERK2; extracellular signal-regulated kina

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

Activation of the transcription factor NFAT1: concerted or modular regulation?

Keywords: NES; nuclear export signal; NLS; nuclear localisation signal; SP region; serine and proline-rich region; SRR region; serine-rich region; NFAT; nuclear factor of activated T-cells; MAP kinase; mitogen-activated protein kinase; CKI; casein kinase I; GSK3; g

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

Features and potentials of ATP-site directed CK2 inhibitors

Keywords: CK2; casein kinase 2; Dyrk1A; dual specificity tyrosine phosphorylation-regulated kinase; DMAT; 4,5,6,7-tetrabromo-2-(dimethylamino)benzimidazole; GSK3; glycogen synthase kinase 3; HSP90; heat shock protein; MNX; 1,8-dihydroxy-4-nitro-xanthen-9-one; PI3 k

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Intracellular signal transduction pathways induced by leptin in C2C12 cells

Keywords: Leptin; C2C12 cells; Signal transduction; PI3K; phosphatidylinositol 3 kinase; Akt/PKB; protein kinase B; GSK3; glycogen synthase kinase 3; PKC-ζ; protein kinase C ζ; ERKs; extracellular signal-regulated kinases; P38 MAPK; p38 mitogen-activated protein

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Optimal Classes of Chemotherapeutic Agents Sensitized by Specific Small-Molecule Inhibitors of Akt In Vitro and In Vivo

Keywords: Akt; inhibitors; chemosensitization; apoptosis; synergy; PI3K; phosphatidyl inositol 3' kinase; PTEN; phosphatase and tensin homolog deleted in chromosome 10; GSK3; glycogen synthase kinase 3;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Substrate specificity of protein kinases and computational prediction of substrates

Keywords: AGC; protein kinases A, G, C; AMPK; AMP-activated protein kinase; CaMK; calmodulin-dependent kinase; CDK; cyclin-dependent kinase; CMGC kinases; cyclin-dependent kinases, MAP kinases, glycogen synthase kinase 3 (GSK3) and CK2-related protein kinases; FRET

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Glycogen synthase kinase 3 has a proapoptotic function in Hydra gametogenesis

Keywords: Cnidaria; Hydra; GSK3; Wnt; Oogenesis; Gametogenesis; Apoptosis; Nurse cell;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

Role of cyclin-dependent kinase 5 and its activator P35 in local axon and growth cone stabilization

Keywords: axonal growth; navigation; microtubules; nervous system development; Cdk5; cyclin-dependent kinase 5; E; embryonic day; GCL; ganglion cell layer; GSK3; glycogen synthase kinase 3; mab; monoclonal antibody; MAP1B; microtubule-associated protein 1B; NEC; ne

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2005 سفارش ترجمه

Protein kinases as targets for antimalarial intervention: Kinomics, structure-based design, transmission-blockade, and targeting host cell enzymes

Keywords: CamK; calmodulin kinase; CDK; cyclin-dependent kinase; CDPK; calcium-dependent protein kinase; CK1; casein kinase 1; CQ; chloroquine; EPK; eukaryotic protein kinase domain; ERK; extracellular signal-regulated kinase; GSK3; glycogen synthase kinase 3; Hb;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2005 سفارش ترجمه