کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10958165 1099976 2013 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Regulatory mechanisms for glycogenolysis and K+ uptake in brain astrocytes
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیولوژی سلول
پیش نمایش صفحه اول مقاله
Regulatory mechanisms for glycogenolysis and K+ uptake in brain astrocytes
چکیده انگلیسی
Recent advances in brain energy metabolism support the notion that glycogen in astrocytes is necessary for the clearance of neuronally-released K+ from the extracellular space. However, how the multiple metabolic pathways involved in K+-induced increase in glycogen turnover are regulated is only partly understood. Here we summarize the current knowledge about the mechanisms that control glycogen metabolism during enhanced K+ uptake. We also describe the action of the ubiquitous Na+/K+ ATPase for both ion transport and intracellular signaling cascades, and emphasize its importance in understanding the complex relation between glycogenolysis and K+ uptake.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neurochemistry International - Volume 63, Issue 5, November 2013, Pages 458-464
نویسندگان
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