دانلود مقالات ISI درباره آلدووز ردوکتاز + ترجمه فارسی

Structural basis for the inhibition of AKR1B10 by the C3 brominated TTNPB derivative UVI2008

Keywords: آلدووز ردوکتاز; Cancer; Enzyme inhibitor; Psoriasis; RAR/RXR agonist; Retinoic acid; Skin disease; AR; Aldose Reductase; AKR; Aldo-Keto Reductase; AKR1B10; AKR family member 1B10; AKR1B15; AKR family member 1B15; AKR1A1; AKR family member 1A1 or aldehyde reductase; ARIs;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Characterization of DHDP, a novel aldose reductase inhibitor isolated from Lysimachia christinae

Keywords: آلدووز ردوکتاز; 1D; one-dimensional; 2D; two-dimensional; AR; aldose reductase; ARI; aldose reductase inhibitor; BD; binding degree; CH2Cl2; methylene chloride; EALC; the ethyl acetate fraction of Lysimachia christinae methanolic extract; EtOAc; ethyl acetate; FAB-MS; fa

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Interaction of AR and iNOS in lens epithelial cell: A new pathogenesis and potential therapeutic targets of diabetic cataract

Keywords: آلدووز ردوکتاز; Diabetic cataract; Aldose reductase; Inducible nitric oxide synthase; Interaction;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Identification of new potent inhibitor of aldose reductase from Ocimum basilicum

Keywords: آلدووز ردوکتاز; Ocimum basilicum; Aldose reductase; Aldehyde reductase; Docking studies; Diabetic complications;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Triterpenes and meroterpenes from Ganoderma lucidum with inhibitory activity against HMGs reductase, aldose reductase and α-glucosidase

Keywords: آلدووز ردوکتاز; Ganoderma lucidum; Triterpenoids; Farnesyl hydroquinone; Triterpene-farnesyl hydroquinone conjugates; HMG-CoA reductase; Aldose reductase; α-Glucosidase;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

4-Hydroxynonenal metabolites and adducts in pre-carcinogenic conditions and cancer

Keywords: آلدووز ردوکتاز; ABC transporters; ATP-binding cassette transporters; AhR; aryl hydrocarbon receptor; AKR; aldo-keto reductase; Akt; protein kinase B; ALDH; aldehyde dehydrogenase; AOR; alkenal/one oxidoreductase; AP-1; activator Protein-1; AR; aldose reductase; ARE/EpRE;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Aldose reductase (AKR1B) deficiency promotes phagocytosis in bone marrow derived mouse macrophages

Keywords: آلدووز ردوکتاز; Aldose reductase; Macrophages; Metabolism; Inflammation; Innate immunity; Phagocytosis;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2017 سفارش ترجمه

AR C-106T gene polymorphism and diabetic nephropathy in the Eastern Asians with T2DM: A meta-analysis including 2120 subjects

Keywords: آلدووز ردوکتاز; Aldose reductase; C-106T; Polymorphism; Diabetic nephropathy; Type 2 diabetes mellitus;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2017 سفارش ترجمه

Therapeutic journey of 2,4-thiazolidinediones as a versatile scaffold: An insight into structure activity relationship

Keywords: آلدووز ردوکتاز; Thiazolidinedione; PPARγ; Antihyperglycemic; Anticancer; Antimicrobial; AI-2; Auto inducer-2; ATP; Adenosine triphosphate; ALR; Aldose reductase; COX; Cyclooxygenase; EC50; Half maximal effective concentration; ED50; Median effective dose; FFAR1; Free fa

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis of benzothiadiazine derivatives exhibiting dual activity as aldose reductase inhibitors and antioxidant agents

Keywords: آلدووز ردوکتاز; Aldose reductase; Benzothiadiazine derivatives; Antioxidant activity;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Protective effect of Tephrosia purpurea in diabetic cataract through aldose reductase inhibitory activity

Keywords: آلدووز ردوکتاز; Tephrosia purpurea; Diabetic cataract; Aldose reductase; Rutin

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

The inhibitory activity of aldose reductase of flavonoid compounds: Combining DFT and QSAR calculations

Keywords: آلدووز ردوکتاز; QSAR model; DFT study; Flavonoids; Aldose reductase; Artificial neural network

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Coumarin-thiazole and -oxadiazole derivatives: Synthesis, bioactivity and docking studies for aldose/aldehyde reductase inhibitors

Keywords: آلدووز ردوکتاز; Coumarin; Thiazole; Oxadiazole; Aldose reductase; Molecular docking; Enzyme inhibition;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

In vitro and in vivo inhibition of aldose reductase and advanced glycation end products by phloretin, epigallocatechin 3-gallate and [6]-gingerol

Keywords: آلدووز ردوکتاز; Diabetes; Aldose reductase; Enzyme kinetics; Bioactive compounds; Functional foods;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

A combination of the main constituents of Fufang Xueshuantong Capsules shows protective effects against streptozotocin-induced retinal lesions in rats

Keywords: آلدووز ردوکتاز; AGEs; advanced glycation end products; AR; aldose reductase; cFXT; combination of main constituents of Fufang Xueshuantong Capsule; Contr.; control group; DR; diabetic retinopathy; HXBJJ; erythrocyte aggregation indexes; FXT; Fufang Xueshuantong Capsule;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2016 سفارش ترجمه

Cornus mas L. (cornelian cherry), an important European and Asian traditional food and medicine: Ethnomedicine, phytochemistry and pharmacology for its commercial utilization in drug industry

Keywords: آلدووز ردوکتاز; AAE; ascorbic acid equivalent; AAPH; 2,2′-Azobis(2-amidinopropane) dihydrochloride; ABTS; 2,2-Azinobis-3-ethylbenzothiazoline-6-sulfonic acid; AD; Alzheimer's disease; AFLP; Amplified fragment length polymorphism; AIP; Atherogenic index parameter; ALP;

دانلود رایگان متن کامل مقاله ISI 71 صفحه سال انتشار : 2016 سفارش ترجمه

Acylated flavonol glycosides and δ-truxinate derivative from the aerial parts of Lysimachia clethroides

Keywords: آلدووز ردوکتاز; Lysimachia clethroides; Acylated flavonol glycoside; δ-Truxinate derivative; Aldose reductase;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2015 سفارش ترجمه

Aldose reductase inhibition of a saponin-rich fraction and new furostanol saponin derivatives from Balanites aegyptiaca

Keywords: آلدووز ردوکتاز; Balanites aegyptiaca; Zygophyllaceae; Diabetes; Furostane; Aldose reductase; Preparative HPLC; MeFr; methylene chloride fraction; EtFr; ethyl acetate fraction; BuFr; n-butanol saturated with water fraction; RwFr; remaining water fraction;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Anti-osmotic and antioxidant activities of gigantol from Dendrobium aurantiacum var. denneanum against cataractogenesis in galactosemic rats

Keywords: آلدووز ردوکتاز; DC; diabetic cataracts; AR; aldose reductase; NO; nitric oxide; iNOS; inducible nitric oxide synthase; ARI; aldose reductase inhibitors; PBS; phosphate buffer saline; FBS; fetal bovine serum; NIH; National Institute of Health; MD; molecular docking; PDB;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Basic nutritional investigationVitamin K1 alleviates streptozotocin-induced type 1 diabetes by mitigating free radical stress, as well as inhibiting NF-κB activation and iNOS expression in rat pancreas

Keywords: آلدووز ردوکتاز; Diabetes; Type 1 diabetes; Pancreas; Aldose reductase; Vitamin K; Oxidative stress; Antioxidant;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Hyperglycemia and redox status regulate RUNX2 DNA-binding and an angiogenic phenotype in endothelial cells

Keywords: آلدووز ردوکتاز; AR; aldose reductase; D-ELISA; DNA-based enzyme-linked immunosorbent assay; DTT; dithiothreitol; EMSA; electrophoretic mobility shift assay; HAdEC; human microvascular adipose-derived ECs (HAdEC); HBME; human bone marrow microvascular ECs; HG; hyperglycem

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Mechanisms of CDDO-imidazolide-mediated cytoprotection against acrolein-induced neurocytotoxicity in SH-SY5Y cells and primary human astrocytes

Keywords: آلدووز ردوکتاز; AR; aldose reductase; BSA; bovine serum albumin; BSO; buthionine sulfoximine; CDDO-Im; triterpenoid 2-cyano-3,12-dixooleana-1,9-dien-28-imidazolide; CDNB; 1-chloro-2,4-dinitrobenzene; DMEM; Dulbecco's modified Eagle's medium; FBS; fetal bovine serum;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

SIRT1 contributes to aldose reductase expression through modulating NFAT5 under osmotic stress: In vitro and in silico insights

Keywords: آلدووز ردوکتاز; AK; acetyllysine; AP-1; activator protein 1; AR; aldose reductase; BGT1; betaine/gamma-aminobutyric acid transporter; Egr-1; early growth response protein 1; FSP27; fat-specific protein 27; HSP90; heat shock protein 90; NAD+; nicotinamide adenine dinucleo

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Triple aldose reductase/α-glucosidase/radical scavenging high-resolution profiling combined with high-performance liquid chromatography-high-resolution mass spectrometry-solid-phase extraction-nuclear magnetic resonance spectroscopy for identification of

Keywords: آلدووز ردوکتاز; High-resolution bioactivity profiling; HPLC-HRMS-SPE-NMR; Radix Scutellariae; α-Glucosidase; Aldose reductase; Radical scavenging;

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2015 سفارش ترجمه

Original ResearchAssociation of Diabetic Autonomic Neuropathy with Red Blood Cell Aldose Reductase Activity

Keywords: آلدووز ردوکتاز; polyol pathway; aldose reductase; diabetic autonomic neuropathy; autonomic function tests; voie des polyols; aldose réductase; neuropathie diabétique autonome; explorations fonctionnelles du système nerveux autonome;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Additive effect of aldose reductase Z-4 microsatellite polymorphism and glycaemic control on cataract development in type 2 diabetes

Keywords: آلدووز ردوکتاز; Aldose reductase; Genetic polymorphism; Cataract; Glycaemic control; Type 2 diabetes

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Synthesis and biological evaluation of steroidal derivatives as selective inhibitors of AKR1B10

Keywords: آلدووز ردوکتاز; Aldose reductase; AKR1B10; Inhibitors; Steroidal derivatives; Molecular docking

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Tonicity-responsive enhancer binding protein regulates the expression of aldose reductase and protein kinase C δ in a mouse model of diabetic retinopathy

Keywords: آلدووز ردوکتاز; aldose reductase; protein kinase C; TonEBP; diabetic retinopathy; hyperglycemia;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Effects of C-glycosylation on anti-diabetic, anti-Alzheimer's disease and anti-inflammatory potential of apigenin

Keywords: آلدووز ردوکتاز; ACh; acetylthiocholine iodide; AChE; acetylcholinesterase; AGEs; advanced glycation endproducts; AR; aldose reductase; ARI; aldose reductase inhibitor; AMT; 2-amino-5,6-dihydro-6-methyl-4H-1,3-thiazine hydrochloride; AD; Alzheimer's disease; Aβ; amyloi

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Aldose reductase inhibition suppresses azoxymethane-induced colonic premalignant lesions in C57BL/KsJ-db/db mice

Keywords: آلدووز ردوکتاز; Aldose reductase; Colon cancer; Obesity; Oxidative stress and inflammation;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Vicenin 2 isolated from Artemisia capillaris exhibited potent anti-glycation properties

Keywords: آلدووز ردوکتاز; AGEs; advanced glycation end products; AR; aldose reductase; NADPH; β-nicotinamide adenine dinucleotide phosphate; BSA; bovine serum albumin; CML; Nε-(carboxymethyl) lysine; DMF; 1-deoxy-1-demorpholino-d-fructose; DMSO; dimethyl sulfoxide; DNPH; 2,4-din

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Predictive QSAR modeling of aldose reductase inhibitors using Monte Carlo feature selection

Keywords: آلدووز ردوکتاز; Aldose reductase; Aldose reductase inhibitor; QSAR; Monte Carlo; MC-MLR

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Sfmbt2 10th intron-hosted miR-466(a/e)-3p are important epigenetic regulators of Nfat5 signaling, osmoregulation and urine concentration in mice

Keywords: آلدووز ردوکتاز; 3′UTR; 3′-untranslated region; AVP; arginine vasopressin; Aqp1/2/3; aquaporin-1/2/3; Ar; aldose reductase; Cdkn1c or p57; Cyclin-dependent kinase inhibitor 1C; C2MC; Chromosome 2 miRNA cluster; Dcx; Doublecortin; ddAVP; 1-desamino-8-d-arginine vasopre

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Inhibitory effect of banana (Musa sp. var. Nanjangud rasa bale) flower extract and its constituents Umbelliferone and Lupeol on α-glucosidase, aldose reductase and glycation at multiple stages

Keywords: آلدووز ردوکتاز; Diabetes mellitus; Ethanol extract; α-Glucosidase inhibitors; Glycation; Aldose reductase; Umbelliferone; Lupeol

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Bioflavonoid ellagic acid inhibits aldose reductase: Implications for prevention of diabetic complications

Keywords: آلدووز ردوکتاز; Aldose reductase; Aldehyde reductase; Diabetic cataract; Ellagic acid; Lens opacity; Sorbitol;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Symplocos cochinchinensis attenuates streptozotocin-diabetes induced pathophysiological alterations of liver, kidney, pancreas and eye lens in rats

Keywords: آلدووز ردوکتاز; Symplocos cochinchinensis; Diabetes; Streptozotocin; Aspartate aminotransferase; Creatinine; Pancreas; Insulin; % HbA1c; Carbonyl content; Aldose reductase

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Aldose reductase regulates miR-200a-3p/141-3p to coordinate Keap1-Nrf2, Tgfβ1/2, and Zeb1/2 signaling in renal mesangial cells and the renal cortex of diabetic mice

Keywords: آلدووز ردوکتاز; 3′UTR; 3′-untranslated region; ACVR2B; activin receptor type 2B; AR/Ar; aldose reductase; ARI; aldose reductase inhibitor; BT; KspAr+/−::Ar−/− bitransgenics; Col4; collagen IV; DN; diabetic nephropathy; E-cad; E-cadherin; ECM; extracellular matr

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Association study of sorbitol dehydrogenase −888G>C polymorphism with type 2 diabetic retinopathy in Caucasian-Brazilians

Keywords: آلدووز ردوکتاز; type 2 diabetes; diabetic retinopathy; polyol pathway; sorbitol dehydrogenase; polymorphism; AGEs; Advanced glycation end-products; AR; Aldose reductase; DR; Diabetic retinopathy; NPDR; Non-proliferative diabetic retinopathy; OR; Odds ratio; PKC; Protein

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

Inhibition of aldose reductase by Aegle marmelos and its protective role in diabetic cataract

Keywords: آلدووز ردوکتاز; Aegle marmelos; Aldose reductase; α-Crystallins; Chaperone activity;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Aldose reductase inhibition suppresses colon cancer cell viability by modulating microRNA-21 mediated programmed cell death 4 (PDCD4) expression

Keywords: آلدووز ردوکتاز; Aldose reductase; Colon cancer; PDCD4; miR-21; AMPK;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Anti-neuroinflammatory efficacy of the aldose reductase inhibitor FMHM via phospholipase C/protein kinase C-dependent NF-κB and MAPK pathways

Keywords: آلدووز ردوکتاز; AR; aldose reductase; LPS; lipopolysaccharide; FMHM; (5-formylfuran-2-yl) methyl 4-hydroxy-2-methylenebutanoate; PKC; protein kinase C; PLC; phospholipase C; NF-κB; nuclear factor kappa B; IKK; I kappa B kinase; IκB; inhibitor of kappa B; MAPKs; mitogen

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Aldose reductase inhibition enhances TRAIL-induced human colon cancer cell apoptosis through AKT/FOXO3a-dependent upregulation of death receptors

Keywords: آلدووز ردوکتاز; AOM; azoxymethane; AR; aldose reductase; ARIs; AR inhibitors; CRC; colorectal cancer; DISC; death-inducing signaling complex; DR; death receptor; TNF; tumor necrosis factor; PARP; poly(ADP-ribose) polymerase; TRAIL; tumor necrosis factor-related apoptosis

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2013 سفارش ترجمه

X-ray structure of the V301L aldo–keto reductase 1B10 complexed with NADP+ and the potent aldose reductase inhibitor fidarestat: Implications for inhibitor binding and selectivity

Keywords: آلدووز ردوکتاز; AKR1B10; Aldo–keto reductase; Aldose reductase; Diabetes; Enzyme inhibitor; Fidarestat

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Evaluation of the prostaglandin F synthase activity of human and bovine aldo-keto reductases: AKR1A1s complement AKR1B1s as potent PGF synthases

Keywords: آلدووز ردوکتاز; AA; arachidonic acid; AKR; aldo-keto reductases; BLOTTO; fat-free dry milk in PBS-T; COX; cyclooxygenase; DD3; dihydrodiol dehydrogenase 3; IL-1β; interleukine-1 beta; PBS-T; PBS with Tween 20; PGs; prostaglandins; PGD2; prostaglandin D2; PGE2; prostagla

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Aldo–keto reductases in retinoid metabolism: Search for substrate specificity and inhibitor selectivity

Keywords: آلدووز ردوکتاز; Aldo–keto reductase; Aldose reductase; Retinoid inhibitors; Retinoic acid

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

The molecular basis for inhibition of sulindac and its metabolites towards human aldose reductase

Keywords: آلدووز ردوکتاز; AR, aldose reductase; SLD, sulindac; SLDs, sulindac and its two metabolites; NSAIDs, non-steroidal anti-inflammatory drugs; COXs, cyclooxygenasesSulindac; Metabolite; Tolmetin; Aldose reductase; Crystal structure

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Inhibitory effect of polysaccharides from pumpkin on advanced glycation end-products formation and aldose reductase activity

Keywords: آلدووز ردوکتاز; Pumpkin; Polysaccharide; Aldose reductase; Antiglycation;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Aldose reductase inhibitory activity of alcoholic extract of Pedalium murex Linn fruit

Keywords: آلدووز ردوکتاز; Aldose reductase; Kinetic study; Pedalium murex; Rat lens;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Aldose reductase inhibitory principles from the whole plant of Hybanthus enneaspermus (Linn) F. Muell

Keywords: آلدووز ردوکتاز; Hybanthus enneaspermus; Aldose reductase; Rat lens; Beta sitosterol; diabet; flavonoinds;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Evaluation of in vitro aldose reductase inhibitory potential of different fraction of Hybanthus enneaspermus Linn F. Muell

Keywords: آلدووز ردوکتاز; Hybanthus enneaspermus; Total phenol; Total flavonoid; Rat lens; Aldose reductase; Diabetic cataract; Different fractions;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه