Keywords: مهار کننده آلدوز ردوکتاز; Alcoholic steatosis; Aldose reductase inhibitor; Metabolomics; Polyol pathway; Saturated fatty acid biosynthesis;
مقالات ISI مهار کننده آلدوز ردوکتاز (ترجمه نشده)
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Keywords: مهار کننده آلدوز ردوکتاز; Aldose reductase inhibitor; Diabetic neuropathy; Peripheral sympathetic nerve activity; Action potential;
Keywords: مهار کننده آلدوز ردوکتاز; Aldose reductase; Enzyme inhibitors; Anti-inflammatory agents; Molecular modelling; 5-Arylidene-4-thiazolidinone derivatives; 5-(carbamoylmethoxy)benzylidene-2-oxo/thioxo-4-thiazolidinone derivatives; AGEs; advanced glycation-end products; AR; aldose redu
Keywords: مهار کننده آلدوز ردوکتاز; AGEs; advanced glycation end-products; ALR1; aldehyde reductase; ALR2; aldose reductase; ARI; aldose reductase inhibitor; BEI; binding efficiency index; DHN; 1,4-dihydroxynonene; GSH; glutathione; HNE; 4-hydroxynonenal; LE; ligand efficiency; LELP; ligand
Keywords: مهار کننده آلدوز ردوکتاز; Diabetic retinopathy; Diabetic cataract; Diabetic keratopathy; Aldose reductase inhibitor; Kinostat®
Pistafolin B is the major aldose reductase inhibitor of the pods of tara [Caesalpinia spinose (Molina) Kuntze]
Keywords: مهار کننده آلدوز ردوکتاز; 1H NMR; proton nuclear magnetic resonance; ANOVA; one-way analysis of variance; AR; aldose reductase; ARI; aldose reductase inhibitor; CH2Cl2; methylene chloride; EI-MS; electron ionization mass spectrometry; EtOAc; ethyl acetate; FBS; foetal bovine serum
Regulation on SIRT1-PGC-1α/Nrf2 pathway together with selective inhibition of aldose reductase makes compound hr5F a potential agent for the treatment of diabetic complications
Keywords: مهار کننده آلدوز ردوکتاز; Diabetic complications; ROS; Antioxidant; Sirt1; Nrf2; Aldose reductase inhibitor;
Aldose reductase inhibitors attenuate β-amyloid-induced TNF-α production in microlgia via ROS-PKC-mediated NF-κB and MAPK pathways
Keywords: مهار کننده آلدوز ردوکتاز; Neuroinflammation; β-Amyloid; Aldose reductase inhibitor; Sorbinil; Zopolrestat;
Characterization of DHDP, a novel aldose reductase inhibitor isolated from Lysimachia christinae
Keywords: مهار کننده آلدوز ردوکتاز; 1D; one-dimensional; 2D; two-dimensional; AR; aldose reductase; ARI; aldose reductase inhibitor; BD; binding degree; CH2Cl2; methylene chloride; EALC; the ethyl acetate fraction of Lysimachia christinae methanolic extract; EtOAc; ethyl acetate; FAB-MS; fa
1-Acetyl-5-phenyl-1H-pyrrol-3-ylacetate: An aldose reductase inhibitor for the treatment of diabetic nephropathy
Keywords: مهار کننده آلدوز ردوکتاز; 1-Acetyl-5-phenyl-1H-pyrrol-3-ylacetate; Diabetic nephropathy; Aldose reductase inhibitor; Apoptosis;
Characterization of AKR1B16, a novel mouse aldo-keto reductase
Keywords: مهار کننده آلدوز ردوکتاز; Aldose reductase inhibitor; Enzyme kinetics; Gene orthology; Retinaldehyde reductase; Steroid oxidoreductase; Subcellular localization; Î4-Ae; androst-4-ene-3,17-dione; AKR; aldo-keto reductase; AKR1B16; AKR family member 1B16; ARI; aldose reductase inhi
Design and synthesis of chiral 2H-chromene-N-imidazolo-amino acid conjugates as aldose reductase inhibitors
Keywords: مهار کننده آلدوز ردوکتاز; 2H-chromene-3-carboxylicacids; Amino acids; Imidazole; Diabetic complications; Aldose reductase inhibitor; Molecular docking;
A series of pyrido[2,3-b]pyrazin-3(4H)-one derivatives as aldose reductase inhibitors with antioxidant activity
Keywords: مهار کننده آلدوز ردوکتاز; Aldose reductase inhibitor; Antioxidant activity; Pyrido[2,3-b]pyrazin-3(4H)-one; Structure-activity relationship;
Phenolic 4-hydroxy and 3,5-dihydroxy derivatives of 3-phenoxyquinoxalin-2(1H)-one as potent aldose reductase inhibitors with antioxidant activity
Keywords: مهار کننده آلدوز ردوکتاز; Aldose reductase inhibitor; Antioxidant; Quinoxalines; Structure–activity relationships
Effects of C-glycosylation on anti-diabetic, anti-Alzheimer's disease and anti-inflammatory potential of apigenin
Keywords: مهار کننده آلدوز ردوکتاز; ACh; acetylthiocholine iodide; AChE; acetylcholinesterase; AGEs; advanced glycation endproducts; AR; aldose reductase; ARI; aldose reductase inhibitor; AMT; 2-amino-5,6-dihydro-6-methyl-4H-1,3-thiazine hydrochloride; AD; Alzheimer's disease; Aβ; amyloi
Predictive QSAR modeling of aldose reductase inhibitors using Monte Carlo feature selection
Keywords: مهار کننده آلدوز ردوکتاز; Aldose reductase; Aldose reductase inhibitor; QSAR; Monte Carlo; MC-MLR
Aldose reductase regulates miR-200a-3p/141-3p to coordinate Keap1-Nrf2, Tgfβ1/2, and Zeb1/2 signaling in renal mesangial cells and the renal cortex of diabetic mice
Keywords: مهار کننده آلدوز ردوکتاز; 3â²UTR; 3â²-untranslated region; ACVR2B; activin receptor type 2B; AR/Ar; aldose reductase; ARI; aldose reductase inhibitor; BT; KspAr+/â::Arâ/â bitransgenics; Col4; collagen IV; DN; diabetic nephropathy; E-cad; E-cadherin; ECM; extracellular matr
LC–MS/MS method for the quantification of aldose reductase inhibitor – Epalrestat and application to pharmacokinetic study
Keywords: مهار کننده آلدوز ردوکتاز; Epalrestat; Aldose reductase inhibitor; Diabetic neuropathy; LC–MS/MS; Motor nerve conduction velocity; Neuropathy pain
Development and validation of a rapid high-performance liquid chromatography-tandem mass spectrometry method for the determination of WJ-38, a novel aldose reductase inhibitor, in rat plasma and its application to a pharmacokinetic study
Keywords: مهار کننده آلدوز ردوکتاز; Aldose reductase inhibitor; WJ-38; Liquid chromatography-tandem mass spectrometry; Rat plasma; Pharmacokinetics
Inhibition of aldose reductase and anti-cataract action of trans-anethole isolated from Foeniculum vulgare Mill. fruits
Keywords: مهار کننده آلدوز ردوکتاز; Trans-anethole; Aldose reductase inhibitor; Foeniculum vulgare; Anti-cataract; Antidiabetic;
Flavonoids isolated from Syzygium aqueum leaf extract as potential antihyperglycaemic agents
Keywords: مهار کننده آلدوز ردوکتاز; Syzygium aqueum; α-Glucosidase inhibitor; α-Amylase inhibitor; Aldose reductase inhibitor; Advanced glycation end-products inhibitor;
Antioxidant and antiglycemic potential of Peltophorum pterocarpum plant parts
Keywords: مهار کننده آلدوز ردوکتاز; Peltophorum pterocarpum; α-Glucosidase inhibitor; α-Amylase inhibitor; Advanced glycation end-products inhibitor; Aldose reductase inhibitor;
Structure-activity relations on [1-(3,5-difluoro-4-hydroxyphenyl)-1H-pyrrol-3-yl]phenylmethanone. The effect of methoxy substitution on aldose reductase inhibitory activity and selectivity
Keywords: مهار کننده آلدوز ردوکتاز; AKR; aldoketoreductase; ALR1; aldehyde reductase; ALR2; aldose reductase; ARI; aldose reductase inhibitor; PKC; protein kinase C; rmsd; root-mean squared deviation; SDH; sorbitol dehydrogenase; Aldose and aldehyde reductase; ARI; Long-term diabetic compli
Ganoderic acid Df, a new triterpenoid with aldose reductase inhibitory activity from the fruiting body of Ganoderma lucidum
Keywords: مهار کننده آلدوز ردوکتاز; Ganoderma lucidum; Aldose reductase inhibitor; Ganoderic acid
Probenecid treatment enhances retinal and brain delivery of N-4-benzoylaminophenylsulfonylglycine: An anionic aldose reductase inhibitor
Keywords: مهار کننده آلدوز ردوکتاز; Retinal delivery; Brain delivery; Anion transporter; Aldose reductase inhibitor;
Polyol pathway impairs the function of SERCA and RyR in ischemic-reperfused rat hearts by increasing oxidative modifications of these proteins
Keywords: مهار کننده آلدوز ردوکتاز; AR; aldose reductase; ARI; aldose reductase inhibitor; ATP; adenosine triphosphate; E[Ca2+]i; electrically induced calcium transient; GAPDH; glyceraldehydes-3-phosphate dehydrogenase; GSH; glutathione; HR; heart rate; [Ca2+]i; intracellular calcium; I/R;
Research ReportThirteen-month inhibition of aldose reductase by zenarestat prevents morphological abnormalities in the dorsal root ganglia of streptozotocin-induced diabetic rats
Keywords: مهار کننده آلدوز ردوکتاز; Aldose reductase inhibitor; Streptozotocin; Diabetic neuropathy; Dorsal root ganglia;
Inhibition of aldose reductase by dietary antioxidant curcumin: Mechanism of inhibition, specificity and significance
Keywords: مهار کننده آلدوز ردوکتاز; AKR; aldo-keto reductase; ALR1; aldehyde reductase; ALR2, AKR1B1; human aldose reductase; HSIR, AKR1B10; human small intestine reductase; ARI; aldose reductase inhibitor; RBC; red blood cells; Aldo-keto reductase; ALR2; AKR1B10; Curcumin; Sorbitol;
Aldose reductase inhibitor counteracts the attenuated adhesion of human corneal epithelial cells induced by high glucose through modulation of MMP-10 expression
Keywords: مهار کننده آلدوز ردوکتاز; Aldose reductase; Matrix metalloproteinase-10; Human corneal epithelial cell; Aldose reductase inhibitor; Diabetic keratoepitheliopathy;
Attenuation of aldose reductase gene suppresses high-glucose-induced apoptosis and oxidative stress in rat lens epithelial cells
Keywords: مهار کننده آلدوز ردوکتاز; Sugar cataract; Aldose reductase; Rat lens epithelial cell; Small interference RNA; Aldose reductase inhibitor
High glucose induction of DNA-binding activity of the transcription factor NFκB in patients with diabetic nephropathy
Keywords: مهار کننده آلدوز ردوکتاز; Nuclear factor kappa B; Diabetic nephropathy; Aldose reductase; Aldose reductase inhibitor; siRNA
Erythrocyte sorbitol level as a predictor of the efficacy of epalrestat treatment for diabetic peripheral polyneuropathy
Keywords: مهار کننده آلدوز ردوکتاز; Aldose reductase inhibitor; Diabetic neuropathy; Epalrestat; Erythrocyte sorbitol level
The role of polyol pathway in high glucose-induced endothelial cell damages
Keywords: مهار کننده آلدوز ردوکتاز; Polyol pathway; Endothelial cell damage; High glucose; Aldose reductase inhibitor; Oxidative stress
Quantitative structure–activity relationship of spirosuccinimide type aldose reductase inhibitors diminishing sorbitol accumulation in vivo
Keywords: مهار کننده آلدوز ردوکتاز; QSAR; Aldose reductase inhibitor; Sorbitol accumulation; Caco-2 cell permeability
Water extract of Aralia elata prevents cataractogenesis in vitro and in vivo
Keywords: مهار کننده آلدوز ردوکتاز; Aralia elata; Anticataract; Diabetes; Aldose reductase inhibitor; Antioxidant; Lens culture; Diabetic animal;
Quantitative structure and aldose reductase inhibitory activity relationship of 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-4-spiro-3â²-pyrrolidine-1,2â²,3,5â²-tetrone derivatives
Keywords: مهار کننده آلدوز ردوکتاز; QSAR; Aldose reductase inhibitor; Genetic function approximation; Physicochemical descriptor;