Keywords: مهار آلوستریک; Allosteric inhibition; Anticoagulants; Thrombin; Heparin-binding site; Enzyme regulation;
مقالات ISI مهار آلوستریک (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: مهار آلوستریک; Allosteric inhibition; PEF(S); Calpain-1 inhibitors; Structure-based design; Docking; PEF(S); penta-EF hand calcium binding domain; TNS; p-toluidinylnaphthalene-6-sulfonate; CysPc; calpain-like protease domain; kDa; kilo Dalton; SAR; structure activity re
Keywords: مهار آلوستریک; MAP2K7; Crystal structure; Stable mutant; Cysteine replacement; Microgravity; Allosteric inhibition; MAP2K; mitogen-activated kinase kinase; JNK; c-jun N-terminal kinase; DVD; domain for versatile docking;
Keywords: مهار آلوستریک; Allosteric site; Ligand binding site predictor; Viral polymerase; Allosteric inhibition
Keywords: مهار آلوستریک; Allosteric inhibition; Anticoagulants; Coagulation; Glycosaminoglycan mimetics; Thrombin;
Novel heparin mimetics reveal cooperativity between exosite 2 and sodium-binding site of thrombin
Keywords: مهار آلوستریک; LMWH; low molecular weight heparin; LMWL; low molecular weight lignin; PEG; polyethylene glycol; UFH; unfractionated heparin; Allosteric inhibition; Exosites; Heparin; Heparin mimetics; Thrombin;
Small molecule targeting of PTPs in cancer
Keywords: مهار آلوستریک; Tyrosine phosphatases; Chemical probes; Drug-like inhibitors; Allosteric inhibition; Cancer;
Exploring neuroprotective potential of Withania somnifera phytochemicals by inhibition of GluN2B-containing NMDA receptors: An in silico study
Keywords: مهار آلوستریک; N-methyl-d-aspartate receptors; Excitotoxicity; Neurodegenerative diseases; Withania somnifera; Allosteric inhibition
On scaffold hopping: Challenges in the discovery of sulfated small molecules as mimetics of glycosaminoglycans
Keywords: مهار آلوستریک; Allosteric inhibition; Anticoagulants; Scaffold hopping; Thrombin; Virtual screening;
Binding sites and hydrophobic pockets in Human Thioredoxin 1 determined by normal mode analysis
Keywords: مهار آلوستریک; Molecular modeling; Normal mode analysis; Human Thioredoxin 1; Binding sites; Allosteric inhibition;
Structure-based design of novel HCV NS5B thumb pocket 2 allosteric inhibitors with submicromolar gt1 replicon potency: Discovery of a quinazolinone chemotype
Keywords: مهار آلوستریک; HCV NS5B polymerase; Thumb pocket 2; Non-nucleoside inhibitor; Allosteric inhibition; Structure-based drug design;
Binding and discerning interactions of PTP1B allosteric inhibitors: Novel insights from molecular dynamics simulations
Keywords: مهار آلوستریک; Molecular modeling; Allosteric inhibition; Binding free energy; B-factor; Per-residue energy decomposition; Hydrogen bond
Discovery and development of the χ-conopeptide class of analgesic peptides
Keywords: مهار آلوستریک; Venom peptide; Cone snail; Norepinephrine transporter; Pain; Allosteric Inhibition
Orally active aminopyridines as inhibitors of tetrameric fructose-1,6-bisphosphatase
Keywords: مهار آلوستریک; Fructose-1,6-bisphosphatase; FBPase; Allosteric inhibition; Structure–activity studies; X-ray crystallography; Genotoxicity; Glucose reduction; db/db Mouse model
Characterization of specific binding by mass spectrometry: Associations of E. coli citrate synthase with NADH and 2-azidoATP
Keywords: مهار آلوستریک; Citrate synthase; Allosteric inhibition; ESI-MS; MALDI-TOF-MS; Peptide mapping; Protein modification; TCA cycle
Structure-based discovery of small molecules targeting different surfaces of protein-kinase CK2
Keywords: مهار آلوستریک; POMs; polyoxometalates; V; vanadium; Mo; molybdenum; W; tungsten; DRB; D-ribofuranosylbenzimidazole; Protein kinase CK2; Non-competitive inhibitor; Allosteric inhibition; Protein-protein interaction;
Sulfonylureido thiazoles as fructose-1,6-bisphosphatase inhibitors for the treatment of Type-2 diabetes
Keywords: مهار آلوستریک; Fructose-1,6-bisphosphatase; Allosteric inhibition; Structure–activity studies; X-ray crystallography; Glucose reduction; db/db Mouse model; Aminothiazole bioactivation
Kinetic properties of Pelophylax esculentus muscle FBPase
Keywords: مهار آلوستریک; FBPase; d-fructose-1,6-bisphosphate 1-phosphohydrolase, [EC 3.1.3.11]; Fru-1,6P2; fructose-1,6-bisphosphate; Fru-2,6P2; fructose-2,6-bisphosphate; BTP; bis-tris-propane; PMSF; phenylmethanesulfonyl fluoride; DTT; dithiothreitol; Fructose-1,6-bisphopha
N114S mutation causes loss of ATP-induced aggregation of human phosphoribosylpyrophosphate synthetase 1
Keywords: مهار آلوستریک; Phosphoribosylpyrophosphate synthetase 1; Superactivity; ATP; Allosteric inhibition; Aggregation effect; Secondary structure
Substrate specificity effects of lipoxygenase products and inhibitors on soybean lipoxygenase-1
Keywords: مهار آلوستریک; LO; lipoxygenase; sLO-1; soybean lipoxygenase-1; 15-hLO-1; human reticulocyte 15-lipoxygenase; AA; arachidonic acid; 15-HPETE; 15-(S)-hydroperoxyeicosatetraenoic acid; 15-HETE; 15-(S)-hydroxyeicosatetraenoic acid (reduced oxidation product of AA); 12-HPET
Crystal structure of HsEg5 in complex with clinical candidate CK0238273 provides insight into inhibitory mechanism, potency, and specificity
Keywords: مهار آلوستریک; HsEg5; Mitotic kinesin; X-ray structure; CK0238273; Allosteric inhibition;
A molecular dynamics study of WPD-loop flexibility in PTP1B
Keywords: مهار آلوستریک; Molecular dynamics; WPD-loop; S-loop; Allosteric inhibition; PTP1B
Development of carboxylic acid replacements in indole-N-acetamide inhibitors of hepatitis C virus NS5B polymerase
Keywords: مهار آلوستریک; Hepatitis C virus; NS5B polymerase; Allosteric inhibition; Indoles; Acid replacements
A targeted molecular dynamics study of WPD loop movement in PTP1B
Keywords: مهار آلوستریک; Targeted molecular dynamics; WPD loop; Allosteric inhibition; PTP1B
The origin of the high sensitivity of muscle fructose 1,6-bisphosphatase towards AMP
Keywords: مهار آلوستریک; FBPase, fructose 1,6-bisphosphatase; F1,6-P2, fructose 1,6-bisphosphate; F2,6-P2, fructose 2,6-bisphosphate; PFK, phosphofructokinase; TNP-AMP, 2′,3′-O-(2,4,6-trinitrophenyl)adenosine 5′-monophosphateMuscle FBPase; Allosteric inhibition; AMP binding; Glyc