Keywords: 5â² UTR; 5â² untranslated region; 3â² UTR; 3â² untranslated region; ALPL; alkaline phosphatase liver-type; AP; alkaline phosphatase; CKD; chronic kidney disease; DNE; dominant negative effect; ECM; extracellular matrix; ERT; enzyme replacement therapy
مقالات ISI (ترجمه نشده)
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Keywords: Galectin-3; Bone remodeling; Bone strength; Osteoblasts; Osteoclasts; Macrophages; VSMCs; vascular smooth muscle cells; Lgal-3â/â; galectin-3 knockout; Runx2; Runt-related transcription factor 2; WT; wild type; μCT; micro-computed tomography; BV/TV;
Keywords: ECM; extracellular matrix; DC; dental cementum; AB; alveolar bone; DE; dentin; LCM; laser capture microdissection; LC-MS/MS; liquid chromatography coupled to tandem mass spectrometry; COL1A1; collagen alpha-1(I) chain; COL12A1; collagen alpha-1(XII) chain
Keywords: Alkaline phosphatase; Hypophosphatasia; Mutation analysis; Pyridoxal phosphate; Phosphoethanolamine; ALPL
Keywords: ALP; alkaline phosphatase; ALPL; alkaline phosphatase bone, liver, kidney; BMD; bone mineral density; BMP; bone morphogenetic protein; BMPR; BMP receptor; BRE; BMP responsive element; co-SMAD; common-mediator SMAD; DKK1; dickkopf Wnt signaling pathway inh
Keywords: Asthma; inflammatory phenotypes; gene expression; induced sputum; neutrophils; eosinophils; ACQ; Asthma Control Questionnaire; ALPL; Alkaline phosphatase, tissue-nonspecific isozyme; AUC; Area under the curve; BIRC3; Baculoviral IAP repeat containing 3; B
Enzyme replacement therapy in perinatal hypophosphatasia: Case report of a negative outcome and lessons for clinical practice
Keywords: Hypophosphatasia; Alkaline phosphatase; ALPL; Skeletal dysplasia; Enzyme replacement therapy; Asfotase alfa; Orphan drug;
The MEK5/ERK5 mitogen-activated protein kinase cascade is an effector pathway of bone-sustaining bisphosphonates that regulates osteogenic differentiation and mineralization
Keywords: ANOVA; analysis of variance; ANT; adenine-nucleotide-translocase; ALPL; alkaline phosphatase; Apppl; ATP analogue triphosphoric acid-1-adenosine-5â²yl ester 3-(3-methylbut-3-enyl) ester; BP; bisphosphonate; EC; endothelial cell; eNOS; endothelial nitric
Repeatedly low plasma alkaline phosphatase in a 56-year-old woman. A case of hypophosphatasia diagnosed in adulthood
Keywords: HPP; hypophosphatasia; ALP; alkaline phosphatase; P-ALP; plasma alkaline phosphatase; TNSALP; the gene encoding the tissue-nonspecific isoenzyme of alkaline phosphatase; ALPL; synonym to TNSALP; PPi; inorganic pyrophosphate; PLP; pyridoxal 5´-phosphate;
Profiling of human epigenetic regulators using a semi-automated real-time qPCR platform validated by next generation sequencing
Keywords: MSC; Mesenchymal stromal/stem cell; AMSC; Adipose-tissue derived mesenchymal stromal/stem cell; RT-qPCR; Real-time reverse transcriptase quantitative polymerase chain reaction; RNA-seq; RNA sequencing; EpiReg; Epigenetic regulator; HAT; Histone acetyl tra
Identification of a p.Arg708Gln variant in COL1A2 in atypical femoral fractures
Keywords: Atypical femoral fractures; ALPL; COL1A2; Bisphosphonates; Genetic variants;
Moderate chronic kidney disease impairs bone quality in C57Bl/6J mice
Keywords: CKD; Chronic Kidney Disease; 5/6 Nx; 5/6th nephrectomy; TPTx; thyroparathyroidectomy; qBSE; quantitative backscattered scanning electron microscopy; BUN; blood urea nitrogen; PTH; parathyroid hormone; BV/TV; trabecular bone volume fraction; Tb.N; trabecul
Antiadipogenic and proosteogenic effects of luteolin, a major dietary flavone, are mediated by the induction of DnaJ (Hsp40) Homolog, Subfamily B, Member 1
Keywords: Pparγ; peroxisome proliferator activated receptor γ; aP2; adipocyte protein 2; siRNA; small interfering RNA; MSC; mesenchymal stem cells; DMI; Dexamethasone, IBMX, and Insulin; Dnajb1; DnaJ (Hsp40) Homolog, Subfamily B, Member 1; LCA; licochalcone A; TN
Simvastatin coating of TiO2 scaffold induces osteogenic differentiation of human adipose tissue-derived mesenchymal stem cells
Keywords: hAD-MSCs; human adipose tissue-derived mesenchymal stem cells; TiO2; titanium dioxide; SIM; simvastatin; OPN; osteopontin protein; SPP1; osteopontin mRNA; OPG; osteoprotegerin protein; TNFRSF11B; osteoprotegerin mRNA; OC; osteocalcin protein; BGLAP; osteo
p107-Dependent recruitment of SWI/SNF to the alkaline phosphatase promoter during osteoblast differentiation
Keywords: pRB; p107; SWI/SNF; Alpl; Osteoblasts;
Involvement of MAPK signaling pathway in the osteogenic gene expressions of Cervi Pantotrichum Cornu in MG-63 human osteoblast-like cells
Keywords: Cervi Pantotrichum Cornu; Osteoblast; MG-63; MAPK; ERK1/2; JNK1/2; p38; ELK1; cJUN; COL1A1; ALPL; BGLAP; SPP1
Novel ALPL genetic alteration associated with an odontohypophosphatasia phenotype
Keywords: Hypophosphatasia; Odontohypophosphatasia; Tissue non-specific alkaline phosphatase; ALPL; Collagen-binding site; Compound heterozygous mutations;
Plasma membrane Pdia3 and VDR interact to elicit rapid responses to 1α,25(OH)2D3
Keywords: 1α,25(OH)2D3; 1α,25-dihydroxyvitamin D3; VDR; vitamin D receptor; Pdia3; protein disulfide isomerase family A, member 3; PLA2; phospholipase A2; PLAA; PLA2 activating protein; PGE2; prostaglandin E2; PI3K; phosphatidylinositol 3-kinases; Alpl; alkaline
Compound heterozygosity of two functional null mutations in the ALPL gene associated with deleterious neurological outcome in an infant with hypophosphatasia
Keywords: Tissue-nonspecific alkaline phosphatase; ALPL; Hypophosphatasia; Encephalopathy
Functional characterization of a novel mutation localized in the start codon of the tissue-nonspecific alkaline phosphatase gene
Keywords: Tissue-nonspecific alkaline phosphatase; ALPL; Hypophosphatasia; Dominant negative effect; Transcript variants; Polymorphism
Transcriptional phenotypes of asthma defined by gene expression profiling of induced sputum samples
Keywords: Asthma phenotypes; gene expression profiling; induced sputum; IL-1; TNF-α; neutrophils; eosinophils; ACQ; Asthma control questionnaire; ALPL; Alkaline phosphatase, tissue-nonspecific isozymes; BCR; B-cell receptor; BMI; Body mass index; FENO; Fractional
Extraction, characterization of polysaccharides from lycium barbarum and its effect on bone gene expression in rats
Keywords: GC–MS; FT-IR; LBP; Osteoporosis; Col5a2; Alpl; BMD