Keywords: بیماری آلزایمر; Alzheimer's disease; Behavioral and psychological symptoms of dementia (BPSD); Gender differences;
مقالات ISI بیماری آلزایمر (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Low serum concentration of free triiodothyronine (FT3) is associated with increased risk of Alzheimer's disease
Keywords: بیماری آلزایمر; Thyroid hormones; Free T3; Mild cognitive impairment; Alzheimer's disease; Dementia;
Role of repulsive forces on self-assembly behavior of amyloid β-peptide (1-40): Molecular dynamics simulation approach
Keywords: بیماری آلزایمر; Self-assembly; Alzheimer's disease; Force field; Hydrophobic forces;
Design and synthesis of thymine modified phthalocyanine for Aβ protofibrils photodegradation and Aβ peptide aggregation inhibition
Keywords: بیماری آلزایمر; Alzheimer's disease; Metal ion recognition; Photodynamic therapy; Aβ protofibrils degradation; Aβ aggregation inhibition;
Identifying Mild Cognitive Impairment and mild Alzheimer's disease based on spontaneous speech using ASR and linguistic features
Keywords: بیماری آلزایمر; Mild cognitive impairment; Alzheimer's disease; Automatic screening; Automatic speech recognition; Natural language processing; Classifier combination;
Topological reorganization of EEG functional network is associated with the severity and cognitive impairment in Alzheimer's disease
Keywords: بیماری آلزایمر; Alzheimer's disease; Electroencephalogram; Cognitive functions; Graph theory; Complex network;
Motor deficits in 16-month-old male and female 3xTg-AD mice
Keywords: بیماری آلزایمر; Alzheimer's disease; 3xTg-AD; Motor behaviour; Mouse model; Aging;
TSPO and amyloid deposits in sub-regions of the hippocampus in the 3xTgAD mouse model of Alzheimer's disease
Keywords: بیماری آلزایمر; Neuroinflammation; Alzheimer's disease; TSPO; CLINDE; DRM106; 3xTgAD; TSPO; 18kDa translocator protein; SPECT; single-photon emission computed tomography;
Circulating APP, NCAM and Aβ serve as biomarkers for Alzheimer's disease
Keywords: بیماری آلزایمر; Circulating biomarker; Alzheimer's disease; Amyloid-precursor protein; Neural cell adhesion molecule; β-Amyloid;
Soluble Aβ1-42 suppresses TNF-α and activates NLRP3 inflammasome in THP-1 macrophages
Keywords: بیماری آلزایمر; Alzheimer's disease; Soluble amyloid-β; TNF-α; NLRP3 inflammasome; NF-κB;
Astroglial water channel aquaporin 4-mediated glymphatic clearance function: A determined factor for time-sensitive treatment of aerobic exercise in patients with Alzheimer's disease
Keywords: بیماری آلزایمر; Aerobic exercise; Alzheimer's disease; Aquaporin 4; Glymphatic system;
A new target for Alzheimer's disease: A small molecule SERCA activator is neuroprotective in vitro and improves memory and cognition in APP/PS1 mice
Keywords: بیماری آلزایمر; Alzheimer's disease; ER stress; SERCA; Drug discovery; Small molecules; Medicinal chemistry; Neurodegeneration;
A cascade synthesis, in vitro cholinesterases inhibitory activity and docking studies of novel Tacrine-pyranopyrazole derivatives
Keywords: بیماری آلزایمر; Multicomponent reaction; Tacrine-pyranopyrazole derivatives; Cholinesterase inhibition; Alzheimer's disease; Docking study;
New AChE inhibitors from microbial transformation of trachyloban-19-oic acid by Syncephalastrum racemosum
Keywords: بیماری آلزایمر; Syncephalastrum racemosum; Biotransformation; Trachyloban-19-oic acid; Acetylcholinesterase; Alzheimer's disease;
ABCA1 rs2230805 and rs2230806 common gene variants are associated with Alzheimer's disease
Keywords: بیماری آلزایمر; Alzheimer's disease; ATP-binding cassette transporter subfamily A member 1 (ABCA1); Single nucleotide polymorphism (SNP); Association study;
Frankincense upregulates the hippocampal calcium/calmodulin kinase II-α during development of the rat brain and improves memory performance
Keywords: بیماری آلزایمر; AD; Alzheimer's disease; CaMK; calcium/calmodulin protein kinase; cDNA; complementary deoxyribonucleic acid; LTP; long-term potentiation; MWM; Morris water maze; PCR; polymerase chain reaction; Calcium/calmodulin kinase II; Frankincense; mRNA expression
Regulatory region single nucleotide polymorphisms of the apolipoprotein E gene as risk factors for Alzheimer's disease
Keywords: بیماری آلزایمر; Alzheimer's disease; Apolipoprotein E; APOE promoter; Single nucleotide polymorphism;
Serum haptoglobin in Chinese patients with Alzheimer's disease and mild cognitive impairment: A case-control study
Keywords: بیماری آلزایمر; Alzheimer's disease; Mild cognitive impairment; Haptoglobin; Inflammation;
Design, synthesis, X-ray studies, and biological evaluation of novel BACE1 inhibitors with bicyclic isoxazoline carboxamides as the P3 ligand
Keywords: بیماری آلزایمر; β-secretase; Alzheimer's disease; Memapsin 2; BACE-1; Isoxazoline;
Discovery of amino-1,4-oxazines as potent BACE-1 inhibitors
Keywords: بیماری آلزایمر; Alzheimer's disease; BACE-1; Amino-1,4-oxazines; pKa; P-gp;
New lignans attenuating cognitive deterioration of Aβ transgenic flies discovered in Acorus tatarinowii
Keywords: بیماری آلزایمر; Acorus tatarinowii; Lignan; Tatarinoid; Transgenic fly; Alzheimer's disease;
Association of GPX1 and GPX4 polymorphisms with episodic memory and Alzheimer's disease
Keywords: بیماری آلزایمر; Alzheimer's disease; MCI; Episodic memory; GPX1; GPX4;
Valproic acid attenuates Aβ25-35-induced neurotoxicity in PC12 cells through suppression of mitochondria-mediated apoptotic pathway
Keywords: بیماری آلزایمر; Alzheimer's disease; PC12 cells; Aβ25-35; Valproic acid; Apoptosis; Oxidative stress; Mitochondrial dysfunction; Inflammation; NF-κB signaling;
Protective effects of silk lutein extract from Bombyx mori cocoons on β-Amyloid peptide-inducedãapoptosis in PC12 cells
Keywords: بیماری آلزایمر; Alzheimer's disease; Silk lutein extract; β-Amyloid; PC12 cells; Apoptosis; Neurodegeneration; Oxidative stress; Bombyx mori cocoons;
In-vitro evaluation and in-silico studies applied on newly synthesized amide derivatives of N-phthaloylglycine as Butyrylcholinesterase (BChE) inhibitors
Keywords: بیماری آلزایمر; Amide; Butyrylcholinesterase (BChE); Alzheimer's disease; Computer aided drug designing (CADD); Molecular docking simulation; In silico studies; Schotten Baumann reaction;
Design, synthesis, and evaluation of polyamine-memantine hybrids as NMDA channel blockers
Keywords: بیماری آلزایمر; Polyamine; NMDA channel blocker; Alzheimer's disease; Memantine; Guanidine;
Saccade latency delays in young apolipoprotein E (APOE) epsilon 4 carriers
Keywords: بیماری آلزایمر; Prosaccade; Antisaccade; APOE polymorphism; LATER model; Alzheimer's disease;
Glucagon like peptide-1 (GLP-1) likes Alzheimer's disease
Keywords: بیماری آلزایمر; GLP-1; Alzheimer's disease; Diabetes; Nervous system;
FKBP12-immunopositive inclusions in patients with α-synucleinopathies
Keywords: بیماری آلزایمر; AD; Alzheimer's disease; α-SYN; α-Synuclein; AT8; anti-human PHF-tau monoclonal; DAB; 3,3â²-diaminobenzidine tetrahydrochloride; DLB; dementia with Lewies; FKBP12; FK506 binding protein 12; GCI; glial cytoplasmic inclusion; MSA; multiple system atrop
Development and validation of an UHPLC-ESI-QTOF-MS method for quantification of the highly hydrophilic amyloid-β oligomer eliminating all-D-enantiomeric peptide RD2 in mouse plasma
Keywords: بیماری آلزایمر; UHPLC-ESI-QTOF-MS; Mouse plasma; D-peptide; Amyloid-β peptide; Therapeutic compound; Alzheimer's disease;
Apigenin as neuroprotective agent: Of mice and men
Keywords: بیماری آلزایمر; Neuroprotection; Alzheimer's disease; Parkinson's disease; Apigenin; Flavonoids;
Aqueous extracts of two tropical ethnobotanicals (Tetrapleura tetraptera and Quassia undulata) improved spatial and non-spatial working memories in scopolamine-induced amnesic rats: Influence of neuronal cholinergic and antioxidant systems
Keywords: بیماری آلزایمر; TT; Tetrapleura tetraptera; QU; Quassia undulata; AD; Alzheimer's disease; AChE; acetylcholinesterase; BChE; butyrylcholinesterase; HPLC-DAD; high-performance liquid chromatography coupled with diode array detector; NOR; novel object recognition test; S
Conversion of iodine to fluorine-18 based on iodinated chalcone and evaluation for β-amyloid PET imaging
Keywords: بیماری آلزایمر; Aβ; β-amyloid; AD; Alzheimer's disease; PET; positron emission tomography; SPECT; single photon emission computed tomography; DMFC; 4-dimethylamino-4â²-fluoro-chalcone; FMC; 4â²-fluoro-4-methylamino-chalcone; DMIC; 4-dimethylamino-4â²-iodo-chalcone
Early Aβ-HBc virus-like particles immunization had better effects on preventing the deficit of learning and memory abilities and reducing cerebral Aβ load in PDAPP mice
Keywords: بیماری آلزایمر; β-amyloid peptide (Aβ); Virus-like particles (VLPs); Amyloid plaque; Immunotherapy; Alzheimer's disease;
Enantiomeric lignans with anti-β-amyloid aggregation activity from the twigs and leaves of Pithecellobium clypearia Benth
Keywords: بیماری آلزایمر; Enantiomers; Lignans; Aβ aggregation; Molecular docking; Molecular dynamics; Alzheimer's disease;
Revealing brain mechanisms of mTOR-mediated translational regulation: Implications for chronic pain
Keywords: بیماری آلزایمر; mTOR; Pain; Multiple sclerosis; Depression; Alzheimer's disease; Parkinson's disease;
Dangguishaoyao-San attenuates LPS-induced neuroinflammation via the TLRs/NF-κB signaling pathway
Keywords: بیماری آلزایمر; DSS; Dangguishaoyao-San; AD; Alzheimer's disease; LPS; lipopolysaccharide; Aβ; amyloid β; NF-κB; nuclear factor κB; IκB; inhibitor of NF-κB; TLR-2; toll-like receptor-2; TLR-4; toll-like receptor-4; TNF-α; tumor necrosis factor-α; iNOS; inducibl
Neuregulin 1 regulates amyloid precursor protein cell surface expression and non-amyloidogenic processing
Keywords: بیماری آلزایمر; Amyloid-precursor protein; Neuregulin 1; Secreted APPα; Non-amyloidogenic processing; ADAM10; AD; Alzheimer's disease; APP; amyloid precursor protein; EGF; epithelial growth factor; ER; endoplasmic reticulum; NRG1; neuregulin; sAPPα; secreted APPα; s
Discovery of novel scaffolds for γ-secretase modulators without an arylimidazole moiety
Keywords: بیماری آلزایمر; Alzheimer's disease; Gamma-secretase modulator; Amyloid-beta peptide; Cytochrome P450 3A4;
A review on the hybrids of hydroxycinnamic acid as multi-target-directed ligands against Alzheimer's disease
Keywords: بیماری آلزایمر; Caffeic acid; Ferulic acid; Hybrids; Multi-target-directed ligands; Alzheimer's disease;
Structure-activity relationship of clovamide and its related compounds for the inhibition of amyloid β aggregation
Keywords: بیماری آلزایمر; Alzheimer's disease; Amyloid aggregation; Clovamide; Structure-activity relationship; Catechol;
Cholinesterase inhibitory alkaloids from the rhizomes of Coptis chinensis
Keywords: بیماری آلزایمر; Coptis chinensis; Alzheimer's disease; Cholinesterase; Protoberberine; Tricyclic amide;
Design and synthesis of donepezil analogues as dual AChE and BACE-1 inhibitors
Keywords: بیماری آلزایمر; Alzheimer's disease; Acetylcholinesterase; β-Secretase 1; Donepezil analogues; Permeability;
Gamma-linolenic acid ameliorates Aβ-induced neuroinflammation through NF-κB and MAPK signalling pathways
Keywords: بیماری آلزایمر; Alzheimer's disease; Amyloid β; Gamma-linolenic acid; Inflammation; NF-κB;
Research reportMotor function deficits in the 12 month-old female 5xFAD mouse model of Alzheimer's disease
Keywords: بیماری آلزایمر; 5xFAD mouse model; Alzheimer's disease; Motor coordination; Gait; Locomotion; Balance; Motor learning; Grip strength; Swimming ability; Auditory startle reflex; Peripheral motor nerves;
Research reportPharmacological activation of the Nrf2 pathway by 3H-1, 2-dithiole-3-thione is neuroprotective in a mouse model of Alzheimer disease
Keywords: بیماری آلزایمر; Alzheimer's disease; D3T; Cognition; Oxidative stress; Hippocampal neurogenesis; Sirt1; Nrf2;
A novel method based on independent component analysis for brain MR image tissue classification into CSF, WM and GM for atrophy detection in Alzheimer's disease
Keywords: بیماری آلزایمر; Independent component analysis; Band expansion process; Brain MRI; Support vector machines; Alzheimer's disease;
A novel Aβ epitope vaccine based on bacterium-like particle against Alzheimer's disease
Keywords: بیماری آلزایمر; Alzheimer's disease; Amyloid-β; Bacterium-like particle; Immunotherapy; Vaccine;
Design, synthesis and evaluation of pterostilbene β-amino alcohol derivatives as multifunctional agents for Alzheimer's disease treatment
Keywords: بیماری آلزایمر; Alzheimer's disease; Pterostilbene β-amino alcohol derivatives; Acetylcholinesterase inhibitors; Aβ aggregation inhibitors; Neuroprotective effects; Multifunctional agents;
Sesamin and sesamolin reduce amyloid-β toxicity in a transgenic Caenorhabditis elegans
Keywords: بیماری آلزایمر; AD; Alzheimer's disease; Aβ; β-amyloid; C. elegans; Caenorhabditis elegans; DMSO; dimethyl sulfoxide; PT50; median paralysis time; Alzheimer's disease; β-Amyloid; Sesame lignans; Sesamin; Sesamolin; Sesamol; Caenorhabditis elegans;