دانلود مقالات ISI درباره بیماری آلزایمر + ترجمه فارسی

Neuroanatomical Distribution of DEK Protein in Corticolimbic Circuits Associated with Learning and Memory in Adult Male and Female Mice

Keywords: بیماری آلزایمر; BLA; basolateral amygdaloid complex; CA; cornu ammonis; CeA; central amygdaloid complex; CNS; central nervous system; DG; dentate gyrus; DP; dorsal peduncular cortex; ENT; entorhinal cortex; GCL; granule cell layer; HNSCC; human head and neck squamous cel

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Galangin's potential as a functional food ingredient

Keywords: بیماری آلزایمر; Galangin; Propolis; Alpinia officinarum; Functional food ingredient; Polypharmacology; Flavonoid; AChE; acetylcholinesterase; AD; Alzheimer's disease; ADME; Administration, Distribution, Metabolism and Excretion; AHR; airway hyperresponsive; AhR; aryl h

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Beta-secretase/BACE1 promotes APP endocytosis and processing in the endosomes and on cell membrane

Keywords: بیماری آلزایمر; Alzheimer's disease; Beta-secretase BACE1; Presenilin 1(PSEN1); Amyloid beta precursor protein (APP); Endocytosis;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

An inorganic overview of natural Aβ fragments: Copper(II) and zinc(II)-mediated pathways

Keywords: بیماری آلزایمر; Metal ions; Alzheimer's disease; Neurodegenerative diseases; Aβ-degrading enzyme; Metallostasis;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Design, synthesis and evaluation of 4′-OH-flurbiprofen-chalcone hybrids as potential multifunctional agents for Alzheimer's disease treatment

Keywords: بیماری آلزایمر; Alzheimer's disease; Flurbiprofen-chalcone hybrids; Multifunctional agents; Monoamine oxidase inhibitors; Aβ aggregation inhibitors; Anti-inflammatory agents;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

The amyloid precursor protein binds to β-catenin and modulates its cellular distribution

Keywords: بیماری آلزایمر; APP; amyloid precursor protein; BACE; beta-APP cleaving enzyme; GSK3; Glycogen Synthase Kinase 3; PCP; planar cell polarity; TCF/LEF; T-cell factor/lymphoid enhancer factor; TopFlash; TCL/LEF-Firefly luciferase; Alzheimer's disease; β-catenin; Amyloid

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Metabolic syndrome marks early risk for cognitive decline with APOE4 gene variation: A case study

Keywords: بیماری آلزایمر; APOE4; Alzheimer's disease; Metabolic syndrome; Ketogenic diet; HIIT;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

The Protective Effects of IGF-I against β-Amyloid-related Downregulation of Hippocampal Somatostatinergic System Involve Activation of Akt and Protein Kinase A

Keywords: بیماری آلزایمر; AC; adenylyl cyclase; AD; Alzheimer's disease; Akt; protein kinase B; Aβ; beta-amyloid; BDNF; brain-derived neurotrophic factor; CCK; cholecystokinin, CRE, cyclic AMP response element; CREB; CRE-binding protein; GABA; γ-aminobutyric acid; GFAF; glial

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

Design and synthesis of gallocyanine inhibitors of DKK1/LRP6 interactions for treatment of Alzheimer's disease

Keywords: بیماری آلزایمر; DKK1/LRP6 interactions; Tau phosphorylation; Phenoxazinone; Alzheimer's disease; Gallocyanine derivatives;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

Design and synthesis of some new carboxamide and propanamide derivatives bearing phenylpyridazine as a core ring and the investigation of their inhibitory potential on in-vitro acetylcholinesterase and butyrylcholinesterase

Keywords: بیماری آلزایمر; Alzheimer's disease; Pyridazine; Acetylcholinesterase inhibitory activity; Butyrylcholinesteraseinhibitory activity; Molecular docking;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

Potent human glutaminyl cyclase inhibitors as potential anti-Alzheimer's agents: Structure-activity relationship study of Arg-mimetic region

Keywords: بیماری آلزایمر; Glutaminyl cyclase inhibitor; Alzheimer's disease; Beta-amyloid;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

Upregulated BMP6 pathway involved in the pathogenesis of Aβ toxicity in vivo

Keywords: بیماری آلزایمر; Bone morphogenetic protein 6; Alzheimer's disease; APP/PS1; CL2006 C. elegans;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

Alzheimer disease associated variants in SORL1 accelerate dementia development in Parkinson disease

Keywords: بیماری آلزایمر; Parkinson's disease; Dementia; Alzheimer's disease; SORL1; Genetic association;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2018 سفارش ترجمه

APOE ε4 is associated with higher levels of CSF SNAP-25 in prodromal Alzheimer's disease

Keywords: بیماری آلزایمر; APOE ε4; Alzheimer's disease; Mild cognitive impairment; SNAP-25; Synaptic function;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2018 سفارش ترجمه

Neuroprotective effects of Bergenia ciliata on NMDA induced injury in SH-SY5Y cells and attenuation of cognitive deficits in scopolamine induced amnesia in rats

Keywords: بیماری آلزایمر; Bergenia ciliate; SH-SY5Y; Scopolamine; Streptozotocin; NMDA; Cholinesterase; Alzheimer's disease;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2018 سفارش ترجمه

The inhibitory effect of chitosan oligosaccharides on β-site amyloid precursor protein cleaving enzyme 1 (BACE1) in HEK293 APPswe cells

Keywords: بیماری آلزایمر; AD; Alzheimer's disease; BACE1; β-secretase or β-site amyloid precursor protein cleaving enzyme 1; Aβ; β-amyloid peptide; APP; amyloid precursor protein; COS; chitosan oligosaccharides; MTT; 3-[4,5-dimethylthiazol-2-yl]- 2,5- diphenyltetrazolium bro

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2018 سفارش ترجمه

Cu and Zn coordination to amyloid peptides: From fascinating chemistry to debated pathological relevance

Keywords: بیماری آلزایمر; AD; Alzheimer's disease; AFM; atomic force microscopy; APP; amyloid precursor protein; Aβ; amyloid-β peptide; DHA; dihydro ascorbic acid; EPR; electron paramagnetic resonance; FAD; familial Alzheimer's disease; hAβ, hIAPP; human peptides; IAPP; isl

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2018 سفارش ترجمه

MFG-E8 inhibits Aβ-induced microglial production of cathelicidin-related antimicrobial peptide: A suitable target against Alzheimer's disease

Keywords: بیماری آلزایمر; Aβ42; MFG-E8; Microglia; CRAMP; Alzheimer's disease;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2018 سفارش ترجمه

Ischemic tau protein gene induction as an additional key factor driving development of Alzheimer's phenotype changes in CA1 area of hippocampus in an ischemic model of Alzheimer's disease

Keywords: بیماری آلزایمر; Alzheimer's disease; Brain ischemia; Tau protein; Gene; Rat hippocampus;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2018 سفارش ترجمه

GIT2-A keystone in ageing and age-related disease

Keywords: بیماری آلزایمر; AD; Alzheimer's disease; ArfGAP; ADP-ribosylation factor GTPase-activating proteins; AT; adipose tissue; ATM; Ataxia Telangiectasia Mutated; ATP; adenosine tri-phosphate; BRCA1; breast cancer type 1 susceptibility protein; CNS; central nervous system; D

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2018 سفارش ترجمه

Reduction of amyloid beta by Aβ3-10-KLH vaccine also decreases tau pathology in 3×Tg-AD mice

Keywords: بیماری آلزایمر; Alzheimer's disease; Aβ3-10-KLH vaccine; Aβ; Tau phosphorylation;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2018 سفارش ترجمه

Unique expression pattern of KIBRA in the enteric nervous system of APP/PS1 mice

Keywords: بیماری آلزایمر; KIBRA; Jejunal myenteric plexus; GABAergic neuron; Alzheimer's disease;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2018 سفارش ترجمه

Soluble TREM2 changes during the clinical course of Alzheimer's disease: A meta-analysis

Keywords: بیماری آلزایمر; Soluble TREM2; Alzheimer's disease; Inflammation; Meta-analysis;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2018 سفارش ترجمه

Characterization of Impaired Cerebrovascular Structure in APP/PS1 Mouse Brains

Keywords: بیماری آلزایمر; AD; Alzheimer's disease; BBB; blood-brain barrier; CNS; Central Nervous System; GFAP; glial fibrillary acidic protein; GLUT1; glucose transporter 1; LRP-1; receptor-related protein-1; ZO-1; zonula occludense-1; Alzheimer's disease; blood brain barri

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2018 سفارش ترجمه

Integrating spatial-anatomical regularization and structure sparsity into SVM: Improving interpretation of Alzheimer's disease classification

Keywords: بیماری آلزایمر; Alzheimer's disease; Support vector machine (SVM); Spatial-anatomical regularization; Structure sparsity; Proximal algorithm;

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2018 سفارش ترجمه

TSPO ligand PK11195 improves Alzheimer-related outcomes in aged female 3xTg-AD mice

Keywords: بیماری آلزایمر; TSPO; translocator protein 18 kD; AD; Alzheimer's disease; Aging; Alzheimer's; β-Amyloid; Neuroinflammation; TSPO;

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2018 سفارش ترجمه

Free-floating adult human brain-derived slice cultures as a model to study the neuronal impact of Alzheimer's disease-associated Aβ oligomers

Keywords: بیماری آلزایمر; Tissue slices; Organotypic culture; Human brain; Alzheimer's disease; Aβ oligomers; Epilepsy;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

An arabinogalactan from fruits of Lycium barbarum L. inhibits production and aggregation of Aβ42

Keywords: بیماری آلزایمر; Lycium barbarum; Polysaccharide; Aβ42; Alzheimer's disease;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

Multifaceted assessment of the APP/PS1 mouse model for Alzheimer's disease: Applying MRS, DTI, and ASL

Keywords: بیماری آلزایمر; Alzheimer's disease; MRI; MRS; ASL; DTI; APP/PS1 transgenic mice;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2018 سفارش ترجمه

The exosome of adipose-derived stem cells reduces β-amyloid pathology and apoptosis of neuronal cells derived from the transgenic mouse model of Alzheimer's disease

Keywords: بیماری آلزایمر; Alzheimer's disease; Amyloid beta; Human adipose stem cells; Exosomes;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2018 سفارش ترجمه

Absence of association of the Ala58Val (rs17571) CTSD gene variant with Parkinson's disease or amyotrophic lateral sclerosis in a Han Chinese population

Keywords: بیماری آلزایمر; Parkinson's disease; Amyotrophic lateral sclerosis; Alzheimer's disease; CTSD gene; rs17571;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2018 سفارش ترجمه

Amylase, glucosidase, tyrosinase, and cholinesterases inhibitory, antioxidant effects, and GC-MS analysis of wild mint (Mentha longifolia var. calliantha) essential oil: A natural remedy

Keywords: بیماری آلزایمر; Mentha longifolia; 1,8-cineol; Linalool; Alzheimer's disease; Integrative medicine; Diabetes mellitus;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

PERK as a hub of multiple pathogenic pathways leading to memory deficits and neurodegeneration in Alzheimer's disease

Keywords: بیماری آلزایمر; Alzheimer's disease; PERK; eIF2α; Translation; BACE1; Aβ; Tau; Learning and memory;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

Promising horizon to alleviate Alzeheimer's disease pathological hallmarks via inhibiting mTOR signaling pathway: A new application for a commonplace analgesic

Keywords: بیماری آلزایمر; Alzheimer's disease; Autophagy; mTOR; Tau phosphorylation; Tramadol;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

Alzheimer's disease-associated ubiquitin mutant Ubb+1: Properties of the carboxy-terminal domain and its influence on biomolecular interactions

Keywords: بیماری آلزایمر; AD; Alzheimer's disease; CSP; chemical shift perturbation; DUB; deubiquitinating enzyme; hetNOE; heteronuclear nuclear Overhauser effects; HSQC; heteronuclear single quantum coherence; POPC; palmitoyl oleoyl phosphatidylcholine; POPG; palmitoyl oleoyl p

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2018 سفارش ترجمه

Competitive homo- and hetero- self-assembly of amyloid-β 1-42 and 1-40 in the early stage of fibrillation

Keywords: بیماری آلزایمر; AD; Alzheimer's disease; Aβ; amyloid-β peptide; Aβ40; amyloid-β peptide (1-40); Aβ42; amyloid β peptide (1-42); APP; amyloid precursor protein; Ala; alanine; ATD; arrival time distribution; CCS; collision cross section; DTIMS; drift tube ion m

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2018 سفارش ترجمه

Investigating the efficacy of a combination Aβ-targeted treatment in a mouse model of Alzheimer's disease

Keywords: بیماری آلزایمر; Aβ; Amyloid-beta peptide; AD; Alzheimer's disease; BBB; Blood-Brain Barrier; CNS; Central nervous system; GFAP; Glial fibrillary acidic protein; MRI; Magnetic resonance image; MRIgFUS; Magnetic resonance image guided focused ultrasound; SI; scyllo-Inos

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2018 سفارش ترجمه

Characterization of a pectin from Lonicera japonica Thunb. and its inhibition effect on Aβ42 aggregation and promotion of neuritogenesis

Keywords: بیماری آلزایمر; Rhamnogalacturonan I (RG-I) pectic polysaccharide; Lonicera japonica Thunb.; Aβ42 aggregation; Neuritogenesis; Alzheimer's disease;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2018 سفارش ترجمه

Myelin changes at the early stage of 5XFAD mice

Keywords: بیماری آلزایمر; Alzheimer's disease; Myelin; 5XFAD mice; Cognition;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

Baicalin and ginsenoside Rb1 promote the proliferation and differentiation of neural stem cells in Alzheimer's disease model rats

Keywords: بیماری آلزایمر; Alzheimer's disease; Neural stem cells; Ginsenoside Rb1; Baicalin;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

Diabetes mellitus and Alzheimer's disease: GSK-3β as a potential link

Keywords: بیماری آلزایمر; 3xTg; triple-transgenic; Aβ; β-amyloid; AD; Alzheimer's disease; ADAS-cog; Alzheimer's Disease Assessment Scale-cognitive subscale; Akt; protein kinase B; APP; amyloid precursor protein; CREB; cAMP-response element binding protein; DM; diabetes mell

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

Functional brain connectivity in Alzheimer's disease: An EEG study based on permutation disalignment index

Keywords: بیماری آلزایمر; Functional brain connectivity; Permutation disalignment index; Alzheimer's disease; EEG;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

CEPO-Fc (An EPO Derivative) Protects Hippocampus Against Aβ-induced Memory Deterioration: A Behavioral and Molecular Study in a Rat Model of Aβ Toxicity

Keywords: بیماری آلزایمر; AD; Alzheimer's disease; Aβ; amyloid β-protein; BBB; blood-brain barrier; CEPO-Fc; carbamylated erythropoietin-Fc; EPO; erythropoietin; ERK; extracellular signal-regulated kinase; JNK; Jun N-terminal kinase; MAPKs; Mitogen-activated protein kinases;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

Astrocytic glutamatergic transporters are involved in Aβ-induced synaptic dysfunction

Keywords: بیماری آلزایمر; Glutamate transporters; Synaptic plasticity; Long-term potentiation; TBOA; Astrocytes; Alzheimer's disease;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

Glia-specific APOE epigenetic changes in the Alzheimer's disease brain

Keywords: بیماری آلزایمر; Apolipoprotein E (APOE); Alzheimer's disease (AD); DNA methylation; Epigenetics; Fluorescence-activated nuclei sorting (FANS); Glia; 7AAD; 7-Aminoactinomycin D; ACTB; actin beta; AD; Alzheimer's disease; AIF1; allograft inflammatory factor 1; APOE; ap

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

Multiscale deep neural network based analysis of FDG-PET images for the early diagnosis of Alzheimer's disease

Keywords: بیماری آلزایمر; Alzheimer's disease; Multiscale deep neural network learning; Metabolism FDG-PET; Early diagnosis;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

Locomotor activity, emotionality, sensori-motor gating, learning and memory in the APPswe/PS1dE9 mouse model of Alzheimer's disease

Keywords: بیماری آلزایمر; Alzheimer's disease; Dementia; Aging; Learning and memory; Locomotor activity; Anxiety; Sensori-motor gating;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

Identifying aMCI with functional connectivity network characteristics based on subtle AAL atlas

Keywords: بیماری آلزایمر; aMCI; amnesic Mild Cognitive Impairment; AD; Alzheimer's Disease; NC; Normal Controls; AAL; Automated Anatomical Labeling; ANIMAL; Automatic Nonlinear Imaging Matching and Anatomical Labeling; CDR; Clinical Dementia Rating Scale; MMSE; Mini-Mental State

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

Untangling Genetic Risk for Alzheimer's Disease

Keywords: بیماری آلزایمر; Alzheimer's disease; Endolysosomal pathway; Functional genomics; Genome-wide association studies; Immune response; Lipid metabolism;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

Flavonoid-rich ethanol extract from the leaves of Diospyros kaki attenuates cognitive deficits, amyloid-beta production, oxidative stress, and neuroinflammation in APP/PS1 transgenic mice

Keywords: بیماری آلزایمر; Alzheimer's disease; Diospyros kaki; Flavonoids; Cognitive dysfunction; Amyloid metabolism; Inflammation;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه