دانلود مقالات ISI درباره بیماری آلزایمر + ترجمه فارسی

Down regulation of pro-inflammatory pathways by tanshinone IIA and cryptotanshinone in a non-genetic mouse model of Alzheimer's disease

Keywords: بیماری آلزایمر; Aβ1-42 (PubChem CID: 57339251); Cryptotanshinone (PubChem CID: 160254); Tanshinone IIA (PubChem CID: 164676); AD; Alzheimer's disease; APP; amyloid precursor protein; CNS; central nervous system; COX; cyclooxygenase; CRY; cryptotanshinone; CTRL; cont

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

A novel Aβ epitope vaccine based on bacterium-like particle against Alzheimer's disease

Keywords: بیماری آلزایمر; Alzheimer's disease; Amyloid-β; Bacterium-like particle; Immunotherapy; Vaccine;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Resource Use and Cost of Alzheimer's Disease in France: 18-Month Results from the GERAS Observational Study

Keywords: بیماری آلزایمر; Alzheimer's disease; costs; France; resource use;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Chemical profile and bioactive properties of the essential oil isolated from Clinopodium serpyllifolium (M.Bieb.) Kuntze growing in Palestine

Keywords: بیماری آلزایمر; Essential oil; Clinopodium serpyllifolium; Treated effluent; Alzheimer's disease; Obesity; Agro-Industrial crops; White-Leaved savory;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

A novel silanization agent based single used biosensing system: Detection of C-reactive protein as a potential Alzheimer's disease blood biomarker

Keywords: بیماری آلزایمر; 3-cyanopropyltrimethoxysilane; C-reactive protein (CRP); Biosensor; Electrochemical impedance spectroscopy (EIS); Alzheimer's disease;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Mechanistic analyses of the suppression of amyloid β42 aggregation by apomorphine

Keywords: بیماری آلزایمر; Aβ; amyloid β-protein; AD; Alzheimer's disease; HFIP; 1,1,1,3,3,3,-hexafluoroisopropyl alcohol; HMQC; heteronuclear multiple quantum coherence; HPLC; high performance liquid chromatography; LC-MS; liquid chromatography-mass spectrometry; LC/Q Tof-MS

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Region- and Cell-specific Aneuploidy in Brain Aging and Neurodegeneration

Keywords: بیماری آلزایمر; AD; Alzheimer's disease; FACS; Fluorescence-Activated Cell Sorting; FCM; Flow Cytometry; FISH; Fluorescence In-situ Hybridization; MVA; mosaic variegated aneuploidy; aging; neurodegeneration; aneuploidy;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Design, synthesis and evaluation of pterostilbene β-amino alcohol derivatives as multifunctional agents for Alzheimer's disease treatment

Keywords: بیماری آلزایمر; Alzheimer's disease; Pterostilbene β-amino alcohol derivatives; Acetylcholinesterase inhibitors; Aβ aggregation inhibitors; Neuroprotective effects; Multifunctional agents;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Down-Regulation of KV4 Channel in Drosophila Mushroom Body Neurons Contributes to Aβ42-Induced Courtship Memory Deficits

Keywords: بیماری آلزایمر; Aβ; amyloid-β; AD; Alzheimer's disease; AE; after eclosion; APP; Aβ precursor protein; CI; courtship index; DI; discrimination index; DNKv4; Kv4 dominant-negative mutant; IA; A-type K+ current; LI; learning index; MB; mushroom body; PN; projection ne

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Neuroprotective effect of a new photobiomodulation technique against Aβ25-35 peptide-induced toxicity in mice: Novel hypothesis for therapeutic approach of Alzheimer's disease suggested

Keywords: بیماری آلزایمر; Alzheimer's disease; Neurodegenerescence; Memory; Neuroinflammation; Amyloid β; Phosphorylated tau; Photobiomodulation; Electromagnetic; LLLT; Magnetic; Photonic; Oxidative stress;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Prion-like Spreading in Tauopathies

Keywords: بیماری آلزایمر; Alzheimer's disease; Animal models; Prion; Strains; Tau; Transmission;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Depressive- and anxiety-like phenotypes in young adult APPSwe/PS1dE9 transgenic mice with insensitivity to chronic mild stress

Keywords: بیماری آلزایمر; Alzheimer's disease; Anxiety; Amyloid beta; Depression; Hippocampus; APP; Swe/PS1dE9 mice;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

HMGB1 Neutralization Attenuates Hippocampal Neuronal Death and Cognitive Impairment in Rats with Chronic Cerebral Hypoperfusion via Suppressing Inflammatory Responses and Oxidative Stress

Keywords: بیماری آلزایمر; AD; Alzheimer's disease; BBB; blood-brain barrier; CAT; catalase; CBF; cerebral blood flow; CCH; chronic cerebral hypoperfusion; DAMPs; damage-associated molecular patterns; EB; Evans Blue; HMGB1; High-mobility group box-1; MDA; decreased malondialdeh

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Multiple pharmacological activities of Caesalpinia crista against aluminium-induced neurodegeneration in rats: Relevance for Alzheimer's disease

Keywords: بیماری آلزایمر; AD; Alzheimer's disease; AlCl3; aluminium chloride; TNFα; tumour necrosis factor; MDA; malondialdehyde; ACh; Eacetylcholinesterase; ACh; acetylcholine; MECC; methanolic extracts of Caesalpinia crista; IL-1; interleukin-1; IL-6; interleukin-6 BDNF brain

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

The role of Plasma Membrane Calcium ATPases (PMCAs) in neurodegenerative disorders

Keywords: بیماری آلزایمر; Alzheimer's disease; Calcium; Excitotoxicity; Neurodegeneration; Parkinson's disease; Protein oxidation;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

A pectin from fruits of Lycium barbarum L. decreases β-amyloid peptide production through modulating APP processing

Keywords: بیماری آلزایمر; Lycium barbarum L.; Pectin; Aβ42; Alzheimer's disease; Amyloid precursor protein processing;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Anosognosia in degenerative brain diseases: The role of the right hemisphere and of its dominance for emotions

Keywords: بیماری آلزایمر; Right hemisphere; Anosognosia; Emotional disturbances; Alzheimer's disease; bvFTD; Qualitative synthesis;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

A new switching-delayed-PSO-based optimized SVM algorithm for diagnosis of Alzheimer's disease

Keywords: بیماری آلزایمر; Alzheimer's disease; Support vector machine; Switching delayed particle swarm optimization; Classification; Principal component analysis;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Association of vascular endothelial growth factor levels in CSF and cerebral glucose metabolism across the Alzheimer's disease spectrum

Keywords: بیماری آلزایمر; Vascular endothelial growth factor; Glucose metabolism; Alzheimer's disease;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Highly functionalized 2-amino-4H-pyrans as potent cholinesterase inhibitors

Keywords: بیماری آلزایمر; 2-amino-4H-pyrans; Alzheimer's disease; AChE; BChE; Molecular docking simulations;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Cortical hypoperfusion and reduced cerebral metabolic rate of oxygen in the arcAβ mouse model of Alzheimer's disease

Keywords: بیماری آلزایمر; Alzheimer's disease; Cerebral amyloidosis; Cerebral blood flow; Cerebral metabolic rate of oxygen; Photoacoustic tomography; Mouse model; Oxygen extraction fraction;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

EPA enriched ethanolamine plasmalogens significantly improve cognition of Alzheimer's disease mouse model by suppressing β-amyloid generation

Keywords: بیماری آلزایمر; Alzheimer's disease; β-amyloid; EPA enriched ethanolamine plasmalogens; Eicosapentaenoic acid; Cognitive function;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Enhanced capillary electrophoretic screening of Alzheimer based on direct apolipoprotein E genotyping and one-step multiplex PCR

Keywords: بیماری آلزایمر; AD; Alzheimer's disease; ApoE; apolipoprotein E; CE; capillary electrophoresis; EtBr; ethidium bromide; LIF; laser-induced fluorescence; PTFE; polytetrafluoroethylene; PVP; poly(vinylpyrrolidone); SGE; slab gel electrophoresis; TBE; tris-borate-EDTA; VP

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Investigation of multi-target-directed ligands (MTDLs) with butyrylcholinesterase (BuChE) and indoleamine 2,3-dioxygenase 1 (IDO1) inhibition: The design, synthesis of miconazole analogues targeting Alzheimer's disease

Keywords: بیماری آلزایمر; Alzheimer's disease; Miconazole derivatives; Multifunctional agents; Butyrylcholinesterase (BuChE); Indoleamine 2,3-dioxygenase 1 (IDO1);

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Systemic or Forebrain Neuron-Specific Deficiency of Geranylgeranyltransferase-1 Impairs Synaptic Plasticity and Reduces Dendritic Spine Density

Keywords: بیماری آلزایمر; ALS; amyotrophic lateral sclerosis; aCSF; artificial cerebrospinal fluid; AD; Alzheimer's disease; ANOVA; analysis of variance; AO; apical oblique; BS; basal shaft; CaMKII α; Ca2+/calmodulin-dependent protein kinase; CNS; central nervous system; Cre+;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Thymoquinone activates MAPK pathway in hippocampus of streptozotocin-treated rat model

Keywords: بیماری آلزایمر; Alzheimer's disease; Hippocampus; Thymoquinone; Streptozotocin; MAPK;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

miR-34a deficiency in APP/PS1 mice promotes cognitive function by increasing synaptic plasticity via AMPA and NMDA receptors

Keywords: بیماری آلزایمر; Aβ; amyloid β; ACSF; artificial cerebrospinal fluid; AD; Alzheimer's disease; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; ANOVA; analysis of variance; APP; amyloid precursor protein; BACE1; beta-secretase 1; BSA; bovine serum albumin;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Long-term treadmill exercise attenuates Aβ burdens and astrocyte activation in APP/PS1 mouse model of Alzheimer's disease

Keywords: بیماری آلزایمر; Alzheimer's disease; Treadmill exercise; β-Amyloid protein; Aβ metabolism; Astrocyte;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Novel 8-hydroxyquinoline derivatives targeting β-amyloid aggregation, metal chelation and oxidative stress against Alzheimer's disease

Keywords: بیماری آلزایمر; 8-Hydroxyquinoline; β-Amyloid; Neuroprotection; Antioxidant; Alzheimer's disease;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Multifunctional 5,6-dimethoxybenzo[d]isothiazol-3(2H)-one-N-alkylbenzylamine derivatives with acetylcholinesterase, monoamine oxidases and β-amyloid aggregation inhibitory activities as potential agents against Alzheimer's disease

Keywords: بیماری آلزایمر; Alzheimer's disease; Benzo[d]isothiazol-3(2H)-one derivatives; Monoamine oxidase inhibitors; Acetylcholinesterase inhibitors; Aβ aggregation inhibitors; Multifunctional agents;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Melatonin improves vascular cognitive impairment induced by ischemic stroke by remyelination via activation of ERK1/2 signaling and restoration of glutamatergic synapses in the gerbil hippocampus

Keywords: بیماری آلزایمر; AD; Alzheimer's disease; CA1; hippocampal Cornu Ammonis 1 area; ERK 1/2; extracellular signal-regulated protein kinases 1/2; F-J B; Fluoro-Jade B; IVD; ischemic vascular dementia; MBP; myelin basic protein; p-ERK1/2; phospho-ERK1/2; tGCI; transient gl

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Searching for improved mimetic peptides inhibitors preventing conformational transition of amyloid-β42 monomer

Keywords: بیماری آلزایمر; Mimetic peptides; Alzheimer's disease; Amyloid β-peptide; Aβ aggregation; Molecular dynamics; Molecular docking;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Effects of biflavonoids from Garcinia madruno on a triple transgenic mouse model of Alzheimer's disease

Keywords: بیماری آلزایمر; CA1 and Sub; subiculum of the hippocampus; EC; entorhinal cortex; Amyg; amygdala. BFbiflavonoid fraction; Veh; vehicle; Alzheimer's disease; Garcinia madruno; Biflavonoid fraction; Emotional behavior; Neuroinflammation;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Yacon leaf extract supplementation demonstrates neuroprotective effect against memory deficit related to β-amyloid-induced neurotoxicity

Keywords: بیماری آلزایمر; Alzheimer's disease; Yacon; Memory; Oxidative stress;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Secondary treated effluent irrigation did not impact chemical composition, and enzyme inhibition activities of essential oils from Origanum syriacum var. syriacum

Keywords: بیماری آلزایمر; Cholinesterase inhibitory activities; Alzheimer's disease; Anti-obesity; Origanum syriacum var. syriacum; Antioxidant; Antibacterial;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

The p38 mitogen activated protein kinase regulates β-amyloid protein internalization through the α7 nicotinic acetylcholine receptor in mouse brain

Keywords: بیماری آلزایمر; p38 mitogen activated protein kinase; α7 nicotinic acetylcholine receptor; Aβ internalization; Apoptosis; Alzheimer's disease;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Novel 3-phenylcoumarin-lipoic acid conjugates as multi-functional agents for potential treatment of Alzheimer's disease

Keywords: بیماری آلزایمر; Alzheimer's disease; Neuroprotective activity; Coumarin; Lipoic acid; Amyloid beta; Antioxidant;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Mitoferrin-1 is Involved in the Progression of Alzheimer's Disease Through Targeting Mitochondrial Iron Metabolism in a Caenorhabditis elegans Model of Alzheimer's Disease

Keywords: بیماری آلزایمر; mfn-1; mitoferrin-1; AD; Alzheimer's disease; ROS; reactive oxygen species; Aβ; β-amyloid; TMRE; tetramethylrhodamine ethyl ester; SLC25A28; solute carrier family 25 member 28; SLC25A37; solute carrier family 25 member 37; PCR; polymerase chain reacti

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Ketogenic diet, high intensity interval training (HIIT) and memory training in the treatment of mild cognitive impairment: A case study

Keywords: بیماری آلزایمر; Alzheimer's disease; Mild cognitive impairment (MCI); Metabolic syndrome (MetS); Ketogenic diet; MoCA; Memory loss;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Plumbagin ameliorates memory dysfunction in streptozotocin induced Alzheimer's disease via activation of Nrf2/ARE pathway and inhibition of β-secretase

Keywords: بیماری آلزایمر; Plumbagin; GFAP; Astrocytes; Trigonelline; β-secretase; Alzheimer's disease;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Phytochemicals as inhibitors of NF-κB for treatment of Alzheimer's disease

Keywords: بیماری آلزایمر; AChE; acetylcholine esterase; AD; Alzheimer's disease; AP1; activator protein 1; APP; amyloid precursor protein; Aβ; amyloid beta; BACE1; β-site of APP cleaving enzyme; Bax; Bcl-2-associated X protein; BBB; blood-brain barrier; Bcl-2; B-cell lymphoma

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Pharmacodynamics in Alzheimer's disease model rats of a bifunctional peptide with the potential to accelerate the degradation and reduce the toxicity of amyloid β-Cu fibrils

Keywords: بیماری آلزایمر; Alzheimer's disease; Amyloid β; Degradation; Copper ions;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Intracerebroventricular injection of Aβ1-42 combined with two-vessel occlusion accelerate Alzheimer's disease development in rats

Keywords: بیماری آلزایمر; Alzheimer's disease; Aβ1-42; Two-vessel occlusion; Cerebral ischemia;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Curcumin derivatives and Aβ-fibrillar aggregates: An interactions' study for diagnostic/therapeutic purposes in neurodegenerative diseases

Keywords: بیماری آلزایمر; Amyloid β fibrillar aggregates; Alzheimer's disease; Curcumin-derivatives; Molecular dynamics simulations; Hippocampal HT-22 mouse cells;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Metal-involved theranostics: An emerging strategy for fighting Alzheimer's disease

Keywords: بیماری آلزایمر; 3,4Apy; 3,4-diaminopyridine; 4Apy; 4-aminopyridine; AChE; acetylcholinesterase; AD; Alzheimer's disease; AFM; atomic force microscopy; APP; amyloid precursor protein; Aβ; amyloid-β peptide; BBB; blood brain barrier; bpy; 2,2-bipyridine; BSA; bovine se

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Effects of thymol on amyloid-β-induced impairments in hippocampal synaptic plasticity in rats fed a high-fat diet

Keywords: بیماری آلزایمر; Thymol; Alzheimer's disease; β-Amyloid; Long term potentiation; Hippocampus; High-fat diet;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

The TRPM2 channel nexus from oxidative damage to Alzheimer's pathologies: An emerging novel intervention target for age-related dementia

Keywords: بیماری آلزایمر; Oxidative damage; Alzheimer's disease; TRPM2 channel; Neurodegeneration; Neuroinflammation; Neurovascular dysfunction;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Research reportMetabolic profiling of the effects of ginsenoside Re in an Alzheimer's disease mouse model

Keywords: بیماری آلزایمر; Alzheimer's disease; Ginsenoside Re; Metabolomics; Ultra performance liquid chromatography-mass spectrometry;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Functional significance of O-GlcNAc modification in regulating neuronal properties

Keywords: بیماری آلزایمر; PTM; post-translational modification; OGT; O-GlcNAc transferase; OGA; O-GlcNAcase; O-GlcNAc; O-linked β-N-acetylglucosamine; UDP-GlcNAc; uridine diphosphate N-acetylglucosamine; GalNAc; N-acetylgalactosamine; Gal; galactose; PSD; postsynaptic density; NF

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Effects of safflower yellow on beta-amyloid deposition and activation of astrocytes in the brain of APP/PS1 transgenic mice

Keywords: بیماری آلزایمر; Alzheimer's disease; Safflower yellow; Beta-amyloid; Astrocytes;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه