The antinociceptive effect of zolpidem and zopiclone in mice
Keywords: ضد انعقاد; Zopiclone; Zolpidem; Opioids; Hotplate; Mice; Antinociception; Drugs interaction;
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The involvement of central cholinergic system in (+)-matrine-induced antinociception in mice
Keywords: ضد انعقاد; (+)-Matrine; Antinociception; Central cholinergic system; Atropine; Opioid receptors; Binding assay;
Remote Nerve Injection of Mu Opioid Receptor Adeno-associated Viral Vector Increases Antinociception of Intrathecal Morphine
Keywords: ضد انعقاد; Recombinant adeno-associated viral; mu opioid receptor; dorsal root ganglia; intrathecal morphine; antinociception;
Antinociceptive activity of new imidazolidine carbonyl derivatives.
Keywords: ضد انعقاد; CNS activity; Opioid-like analgesics; Antinociception; Imidazo[2,1-c] [1,2,4]triazines; Molecular structure; Amido-imido tautomerism;
Antinociceptive effects of choline against acute and inflammatory pain
Keywords: ضد انعقاد; antinociception; choline; hot plate test; formalin test; nicotinic receptors; ACh; acetylcholine; AMMS; Academy of Military Medical Sciences; BBB; blood-brain barrier; α-Bgt; α-bungarotoxin; COX; cyclooxygenase; DRG; dorsal root ganglion; MLA; methyll
Inhibition of acute nociceptive responses in rat spinal cord by a bradykinin B1 receptor antagonist
Keywords: ضد انعقاد; Bradykinin B1 receptor; Antinociception; Spinal cord; (Rat);
Concurrent nociceptive stimulation impairs the anxiolytic effect of midazolam injected into the periaqueductal gray in mice
Keywords: ضد انعقاد; Neurotransmitters, modulators, transporters, and receptors; Behavioral pharmacology; Anxiety; Fear; Different EPM; Antinociception; Midazolam; Periaqueductal gray; Mice;
Analgesic properties of the novel compound M43068 in rat models of acute and neuropathic pain
Keywords: ضد انعقاد; Neuropathic pain; Allodynia; Formalin test; Antinociception; Neurometer; (Rat);
Environmental and intraperitoneal ethanol influences morphine antinociceptive effect in mice
Keywords: ضد انعقاد; Analgesic; Antinociception; Opioid; Morphine; Intraperitoneal ethanol; Environmental ethanol;
Antinociceptive properties of ethanolic extract and fractions of Pterodon pubescens Benth. seeds
Keywords: ضد انعقاد; Pterodon pubescens; Antinociception; Abdominal constriction; Formalin test; Mass spectrometry;
Effects of intraplantar injections of nociceptin and its N-terminal fragments on nociceptive and desensitized responses induced by capsaicin in mice
Keywords: ضد انعقاد; Nociceptin; N-Terminal fragments of nociceptin; Capsaicin-induced nociceptive response; Antinociception; Intraplantar injection; Capsaicin desensitization
Chronic Î9-tetrahydrocannabinol treatment produces antinociceptive tolerance in mice without altering Protein Kinase A activity in mouse brain and spinal cord
Keywords: ضد انعقاد; Cannabinoid; THC; Antinociception; Tolerance; Protein Kinase A;
Antinociceptive, hypothermic, hypotensive, and reinforcing effects of a novel neurotensin receptor agonist, NT69L, in rhesus monkeys
Keywords: ضد انعقاد; Neurotensin; Self-administration; Opioids; Antinociception; Rhesus monkeys;
A comparative study with two types of elevated plus-maze (transparent vs. opaque walls) on the anxiolytic effects of midazolam, one-trial tolerance and fear-induced analgesia
Keywords: ضد انعقاد; BZD; benzodiazepines; EPM; elevated plus-maze; IA; index of antinociception; M; midazolam; OTT; one-trial tolerance; S; saline; TFL; tail-flick latencies; Antinociception; Elevated plus-maze; Midazolam; One-trial tolerance; Transparent walls;
Enhancement of transdermal fentanyl and buprenorphine antinociception by transdermal Î9-tetrahydrocannabinol
Keywords: ضد انعقاد; Fentanyl; Buprenorphine; Î9-THC; Antinociception; Transdermal; (Guinea pig);
Morphine has an antinociceptive effect through activation of the okadaic-acid-sensitive Ser/Thr protein phosphatases PP2A and PP5 estimated by tail-pinch test in mice
Keywords: ضد انعقاد; Sensory system; Pain modulation: pharmacology; Antinociception; Antisense oligodeoxynucleotide; Morphine; Okadaic acid; Serine/threonine protein phosphatase;
BU74, a complex oripavine derivative with potent kappa opioid receptor agonism and delayed opioid antagonism
Keywords: ضد انعقاد; Efficacy; Antinociception; Kappa-opioid; Delayed antagonism;
Physiological control of emotion-related behaviors by endogenous enkephalins involves essentially the delta opioid receptors
Keywords: ضد انعقاد; antidepressant-like effects; mice; antinociception; anxiety; knockout animals; ANOVA; analysis of variance; APN; aminopeptidase N; MOR; mu opioid receptor; NEP; neutral endopeptidase; RB 101; H3N-CH(CH2-CH2-S-CH3)-CH2-S-S-CH2-CH(CH2Ï)-CONH-CH(CH2Ï)-COOC
Effects of N-Methyl-D-Aspartate Receptor Antagonists on Acute Morphine-Induced and l-Methadone-Induced Antinociception in Mice
Keywords: ضد انعقاد; NMDA; opioid; morphine; l-methadone; antinociception; mice;
Inhibitors of serine/threonine protein phosphatases antagonize the antinociception induced by agonists of α2 adrenoceptors and GABAB but not κ-opioid receptors in the tail flick test in mice
Keywords: ضد انعقاد; Antinociception; G protein-coupled receptors; Serine/threonine protein phosphatases; Okadaic acid; Cantharidin; Tail flick test;
Alterations in brain Protein Kinase A activity and reversal of morphine tolerance by two fragments of native Protein Kinase A inhibitor peptide (PKI)
Keywords: ضد انعقاد; Morphine analgesia and tolerance; Protein Kinase A; Antinociception; Pain; Mouse; Protein Kinase A inhibitors;
Action of neuropeptide Y on nociceptive transmission in substantia gelatinosa of the adult rat spinal dorsal horn
Keywords: ضد انعقاد; NPY; SG neurons; blind whole-cell patch-clamp technique; [Leu31; Pro-34]-NPY; BIBP 3226; antinociception; CNQX; 6-cyano-7-nitroquinoxaline-2,3-dione; CNS; central nervous system; CV; conduction velocity; DRG; dorsal root ganglion; EGTA; ethyleneglycolbis-
RFamide-related peptides signal through the neuropeptide FF receptor and regulate pain-related responses in the rat
Keywords: ضد انعقاد; neuropeptide FF; RFamide-related peptide; neuropathic pain; antinociception; potassium channel; hypothalamus; hNPFF2R; human neuropeptide FF2 receptor; i.t.; intrathecal; NPFF; neuropeptide FF; NPFF2R; neuropeptide FF 2 receptor; NTS; nucleus of the solit
Inhibition of morphine tolerance by spinal melanocortin receptor blockade
Keywords: ضد انعقاد; Antinociception; μ-Opioid receptor (MOR); Melanocortin 4 receptor (MC4-R); Morphine tolerance; Spinal cord; Dorsal root ganglia (DRG);
Medetomidine and dexmedetomidine: a review of cardiovascular effects and antinociceptive properties in the dog
Keywords: ضد انعقاد; α2-agonist; antinociception; cardiovascular; dexmedetomidine; dog; medetomidine;
Comparison of the antinociceptive effect of acute morphine in female and male Sprague-Dawley rats using the long-lasting mu-antagonist methocinnamox
Keywords: ضد انعقاد; Neurotransmitters, modulators, transporters, and receptors; Opioid receptors; Mu-opioid receptor; G protein; Antinociception; Methocinnamox; Sex difference; Gender;
Endomorphin 1[Ï] and endomorphin 2[Ï], endomorphins analogues containing a reduced (CH2NH) amide bond between Tyr1 and Pro2, display partial agonist potency but significant antinociception
Keywords: ضد انعقاد; Endomorphins; Analogues; Reduced amide bond; Antinociception; Intracebroventricular; Tail-flick; Formalin-model;
Effect of a selective GABAB receptor agonist baclofen on the μ-opioid receptor agonist-induced antinociceptive, emetic and rewarding effects
Keywords: ضد انعقاد; Emesis; Antinociception; Rewarding effect; Baclofen; Ferret; DMN; dorsal motor nucleus; GABA; γ-aminobutyric acid; CGP 35348; (3-Aminopropyl)(diethoxymetyl)phosphinic acid; CNS; central nervous system; DAMGO; [d-Ala2,N-Me-Phe4,Gly5-ol]enkephalin; DVC; do
Antinociceptive effect of leaf essential oil from Croton sonderianus in mice
Keywords: ضد انعقاد; Croton sonderianus; Antinociception; Essential oil; Chemical nociception; Mouse
Attenuation of capsaicin-induced acute and visceral nociceptive pain by α- and β-amyrin, a triterpene mixture isolated from Protium heptaphyllum resin in mice
Keywords: ضد انعقاد; Protium heptaphyllum; Triterpene mixture; α- and β-amyrin; Capsaicin; Antinociception; Mouse
Behavioral and pharmacological characterization of a distal peripheral nerve injury in the rat
Keywords: ضد انعقاد; CCI; chronic constriction injury; DNI; distal nerve injury; DRG; dorsal root ganglion; SNI; spared nerve injury; SNL; spinal nerve ligation; TCA; tricyclic antidepressant; Antinociception; Gabapentin; Imipramine; Morphine; Neuropathic pain; Plantar nerve;
Involvement of 5-HT2 receptors in the antinociceptive effect of Uncaria tomentosa
Keywords: ضد انعقاد; Uncaria tomentosa; Antinociception; 5-HT2 receptors; Mechanism of action;
Influence of Estrous Cycle and Gonadal Hormone Depletion on Nociception and Opioid Antinociception in Female Rats of Four Strains
Keywords: ضد انعقاد; Opioids; antinociception; gonadal hormones; nociception; rat strains;
Peripheral effect of a kappa opioid receptor antagonist on nociception evoked by formalin injected in TMJ of pregnant rats
Keywords: ضد انعقاد; Pregnancy; Temporomandibular joint; Kappa opioid receptor; Antinociception; Formalin test; Dynorphin;
Peripherally acting NMDA receptor/glycineB site receptor antagonists inhibit morphine tolerance
Keywords: ضد انعقاد; Antinociception; Pain; Tolerance; Glutamate; NMDA receptor/glycineB site antagonist; Blood-brain barrier;
Mechanisms involved in the antinociception caused by agmatine in mice
Keywords: ضد انعقاد; Agmatine; Antinociception; Imidazoline receptors; α2-adrenergic receptors; Nitric oxide system; 5-HT receptors;
Antinociceptive properties of acetylenic thiophene and furan derivatives: Evidence for the mechanism of action
Keywords: ضد انعقاد; Thiophene; Furan; Antinociception; Opioidergic mechanism
Ultra-low-dose naloxone suppresses opioid tolerance, dependence and associated changes in mu opioid receptor-G protein coupling and Gβγ signaling
Keywords: ضد انعقاد; morphine; antinociception; withdrawal; signal transduction; adenylyl cyclase; [3H]DAMGO; Tyr-d-Ala-Gly-N-Methyl-Phe-Gly; GIRK channels; G protein-activated inwardly rectifying potassium channels; KOR; κ opioid receptor; MOR; μ opioid receptor; NLX; nalo
A preclinical comparison between different opioids: antinociceptive versus adverse effects
Keywords: ضد انعقاد; Opioids; Antinociception; Analgesia; Side-effects; Rodent; Fentanyl; Morphine; Buprenorphine; Adverse event;