دانلود مقالات ISI درباره فعالیت ضد تومور + ترجمه فارسی

Isatin-β-thiocarbohydrazones: Microwave-assisted synthesis, antitumor activity and structure-activity relationship

Keywords: فعالیت ضد تومور; Isatin-β-thiocarbohydrazones; Synthesis; Antitumor activity; 3D pharmacophore elucidation;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Design, synthesis and biological evaluation of novel antitumor spirotetrahydrothiopyran-oxindole derivatives as potent p53-MDM2 inhibitors

Keywords: فعالیت ضد تومور; Spirooxindole; p53-MDM2 inhibitors; Antitumor activity; Organocatalytic cascade reaction;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Binary and ternary copper(II) complexes of a new Schiff base ligand derived from 4-acetyl-5,6-diphenyl-3(2H)-pyridazinone: Synthesis, spectral, thermal, antimicrobial and antitumor studies

Keywords: فعالیت ضد تومور; Pyridazinone; Binary and ternary complexes; Schiff base; Thermodynamic parameters; Antimicrobial activity; Antitumor activity;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Spectroscopic, molecular docking and structural activity studies of (E)-N′-(substituted benzylidene/methylene) isonicotinohydrazide derivatives for DNA binding and their biological screening

Keywords: فعالیت ضد تومور; Isonicotinohydrazides; UV spectroscopy; Molecular docking; Binding mode; Binding constant; Antitumor activity;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Ultrasonic nanotherapy of breast cancer using novel ultrasound-responsive alginate-shelled perfluorohexane nanodroplets: In vitro and in vivo evaluation

Keywords: فعالیت ضد تومور; Dox; doxorubicin; Dox-NDs; doxorubicin-loaded Nanodroplets; Dox-ND-US; doxorubicin-loaded Nanodroplets combined with sonication; Ultrasound-responsive nanodroplets; Contrast agents; Biodistribution; Toxicity; Antitumor activity;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis, antifungal and antitumor activity of two new types of imidazolin-2-ones

Keywords: فعالیت ضد تومور; Benzimidazolones; Imidazopyridines; Antifungal activity; Antitumor activity; mTOR;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Discovery of novel antitumor nitric oxide-donating β-elemene hybrids through inhibiting the PI3K/Akt pathway

Keywords: فعالیت ضد تومور; β-Elemene; Furoxan; Antitumor activity; Apoptosis; PI3K/Akt pathway;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis, characterization and antitumor activity of novel ferrocene bisamide derivatives containing pyrimidine-moiety

Keywords: فعالیت ضد تومور; Ferrocene derivative; Pyrimidine-moiety; X-ray structural analysis; Antitumor activity; Cell apoptosis;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Safety against nephrotoxicity in paclitaxel treatment: Oral nanocarrier as an effective tool in preclinical evaluation with marked in vivo antitumor activity

Keywords: فعالیت ضد تومور; Oral nanoemulsion; Paclitaxel; Antitumor activity; Sub-chronic toxicity; Hematological analysis; Histopathology;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Structure-based design and SAR development of 5,6-dihydroimidazolo[1,5-f]pteridine derivatives as novel Polo-like kinase-1 inhibitors

Keywords: فعالیت ضد تومور; PLK1 inhibitor; Structure-based drug design; Antitumor activity; Multidrug resistance;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Enhanced antitumor activity of gemcitabine by polysaccharide-induced NK cell activation and immune cytotoxicity reduction in vitro/vivo

Keywords: فعالیت ضد تومور; SEP; A polysaccharide isolated from Strongylocentrotus nudus egg; TLR; toll-like receptor; NKG2D; natural-killer group 2 member D; DAP10; DNAX-associated protein 10; Akt; protein kinase B; MICA; MHC class I-related chain A; sMICA; soluble MHC class I-rela

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis and biological evaluation of a D-ring-contracted analogue of lamellarin D

Keywords: فعالیت ضد تومور; Alkaloid synthesis; Transition metal catalysis; Natural product mimetics; Antitumor activity; Molecular docking;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Design, synthesis and biological evaluation of novel 4-phenoxyquinoline derivatives containing 3-oxo-3,4-dihydroquinoxaline moiety as c-Met kinase inhibitors

Keywords: فعالیت ضد تومور; Synthesis; 4-Phenoxyquinoline derivatives; c-Met inhibitors; Antitumor activity;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Discovery of novel pyrrolo-pyridine/pyrimidine derivatives bearing pyridazinone moiety as c-Met kinase inhibitors

Keywords: فعالیت ضد تومور; Pyrrolo[2,3-b]pyridines; Pyrrolo[2,3-d]pyrimidines; Pyridazinone; c-Met; Antitumor activity; Docking study;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Platinum(IV) complexes conjugated with phenstatin analogue as inhibitors of microtubule polymerization and reverser of multidrug resistance

Keywords: فعالیت ضد تومور; Antitumor activity; Pt(IV) complex; Tubulin polymerization; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Aptamer-mediated gene therapy enhanced antitumor activity against human hepatocellular carcinoma in vitro and in vivo

Keywords: فعالیت ضد تومور; Recombinant adenovirus; PTEN; Aptamer EpDT3; Gene delivery system; Antitumor activity; Human hepatocellular carcinoma;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis and biological evaluation of novel dinuclear platinum(II) complexes derived from a novel chiral ligand

Keywords: فعالیت ضد تومور; Dinuclear platinum(II) complexes; (1R,1′R,2R,2′R)-N1,N1′-(13-phenylenebis(methylene))dicyclohexane-1; 2-Diamine; Tetradentate ligand; Antitumor activity;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2017 سفارش ترجمه

Novel 6-methoxycarbonyl indolinones bearing a pyrrole Mannich base moiety as angiokinase inhibitors

Keywords: فعالیت ضد تومور; 6-Methoxycarbonyl indolinones; Conformational restriction strategy; Angiokinase inhibitors; Antitumor activity;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2017 سفارش ترجمه

Design, synthesis and biological evaluation of novel 4-(2-fluorophenoxy)quinoline derivatives as selective c-Met inhibitors

Keywords: فعالیت ضد تومور; c-Met; Antitumor activity; Synthesis; Molecular docking; 6,7-Disubstituted-4-(2-fluorophenoxy)quinolines;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2017 سفارش ترجمه

Antitumor activity, pharmacokinetics, tumor-homing effect, and hepatotoxicity of a species cross-reactive c-Met antibody

Keywords: فعالیت ضد تومور; Cancer; c-Met; Fully human antibody; Cross-reactivity; Antitumor activity;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2017 سفارش ترجمه

Effect of selenylation modification on antitumor activity of peptidoglycan from Lactobacillus acidophilus

Keywords: فعالیت ضد تومور; PG; peptidoglycan; Se-PG; selenizing peptidoglycan; TCA; Trichloroacetic acid; PBS; Phosphate-buffered saline; CCK-8; Cell Counting Kit; FT-IR; Fourier Transform infrared spectroscopy; FITC; fluorescein isothiocyanate; Ann; Annexin V; PI; propidium iodide

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2017 سفارش ترجمه

Discovery of a series of 1,3,4-oxadiazole-2(3H)-thione derivatives containing piperazine skeleton as potential FAK inhibitors

Keywords: فعالیت ضد تومور; Benzodioxan; Oxadiazoles; Piperazine; Antitumor activity; FAK;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2017 سفارش ترجمه

Study on antitumor, antioxidant and immunoregulatory activities of the purified polyphenols from pinecone of Pinus koraiensis on tumor-bearing S180 mice in vivo

Keywords: فعالیت ضد تومور; P. koraiensis; Pinus koraiensis; PPP; polyphenols of P. koraiensis pinecone; S180; sarcoma 180; TUNEL; TdT-mediated dUTP nick end labeling; O2−; superoxide anions; H2O2; sydrogen peroxide; SOD; superoxide dismutase; GSH-Px; glutathione peroxidasex; GSH;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2017 سفارش ترجمه

Novel pyrazolo[3,4-d]pyrimidine with 4-(1H-benzimidazol-2-yl)-phenylamine as broad spectrum anticancer agents: Synthesis, cell based assay, topoisomerase inhibition, DNA intercalation and bovine serum albumin studies

Keywords: فعالیت ضد تومور; Pyrazolo[3,4-d]pyrimidine; Benzimidazole; Antitumor activity; ct-DNA; Bovine serum albumin;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2017 سفارش ترجمه

A stable nanoplatform for antitumor activity using PEG-PLL-PLA triblock co-polyelectrolyte

Keywords: فعالیت ضد تومور; Polyelectrolyte; PEG-PLL-PLA; Stable platform; Nanomedicine; Antitumor activity;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2017 سفارش ترجمه

Antitumor activity of conventional and supercritical extracts from Piper nigrum L. cultivar Bragantina through cell cycle arrest and apoptosis induction

Keywords: فعالیت ضد تومور; Piper nigrum; Supercritical CO2; Piperine; Apoptosis; Cell cycle arrest; Antitumor activity;

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis and antitumor activity of novel substituted uracil-1′(N)-acetic acid ester derivatives of 20(S)-camptothecins

Keywords: فعالیت ضد تومور; Camptothecin; Synthesis; Substituted uracil-1′(N)-acetic acid; Antitumor activity; The mechanism of antitumor activity;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2017 سفارش ترجمه

Organotin(IV) carboxylates based on 2-(1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)acetic acid: Syntheses, crystal structures, luminescent properties and antitumor activities

Keywords: فعالیت ضد تومور; Organotin carboxylate; Amide carboxylic acid; Supramolecular structure; Luminescent property; Antitumor activity;

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2017 سفارش ترجمه

Rapid discovery of cyclopamine analogs from Fritillaria and Veratrum plants using LC-Q-TOF-MS and LC-QqQ-MS

Keywords: فعالیت ضد تومور; Fritillaria; Veratrum; Cyclopamine analogs; Chemical screening; Targeted isolation; Antitumor activity;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2017 سفارش ترجمه

Structural variety of mono- and binuclear transition metal complexes of 3-[(2-hydroxy-benzylidene)-hydrazono]-1-(2-hydroxyphenyl)-butan-1-one: Synthesis, spectral, thermal, molecular modeling, antimicrobial and antitumor studies

Keywords: فعالیت ضد تومور; Polydentate Schiff base; Mono- and binuclear complexes; Thermal studies; Molecular modeling; Antimicrobial activity; Antitumor activity;

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis and cytostatic properties of polyfunctionalized furanoallocolchicinoids

Keywords: فعالیت ضد تومور; Colchicine; Allocolchicinoids; Cross-coupling; Antitumor activity; Tubulin binding agents;

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2017 سفارش ترجمه

New quinoline-arylamidine hybrids: Synthesis, DNA/RNA binding and antitumor activity

Keywords: فعالیت ضد تومور; Hybrid molecule; 7-Chloroquinoline; Aromatic amidine; DNA/RNA binding; Antitumor activity;

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2017 سفارش ترجمه

Fragilolides A-Q, norditerpenoid and briarane diterpenoids from the gorgonian coral Junceella fragilis

Keywords: فعالیت ضد تومور; Gorgonian coral; Junceella fragilis; Fragilolides A-Q; Antitumor activity; Anti-HBeAg express; Inhibition of NO production;

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2017 سفارش ترجمه

Novel gold(I) complexes with 5-phenyl-1,3,4-oxadiazole-2-thione and phosphine as potential anticancer and antileishmanial agents

Keywords: فعالیت ضد تومور; Gold(I) complexes; 5-Phenyl-1,3,4-oxadiazole-2-thione; Antitumor activity; Antileishmania; AmB; Amphotericin B; α-MEM; minimum essential medium; BHK-21; Hamster (Mesocricetus auratus) kidney fibroblast; B16-F10; mouse (Mus musculus) skin melanoma cell li

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis, spectroscopic characterization, antimicrobial and antitumor studies of mono-, bi- and tri-nuclear metal complexes of a new Schiff base ligand derived from o-acetoacetylphenol

Keywords: فعالیت ضد تومور; Polydentate Schiff base; o-Acetoacetylphenol; Mono-, bi- and trinuclear complexes; Molecular modeling; Antimicrobial activity; Antitumor activity;

دانلود رایگان متن کامل مقاله ISI 52 صفحه سال انتشار : 2017 سفارش ترجمه

Discovery of 1-(3-aryl-4-chlorophenyl)-3-(p-aryl)urea derivatives against breast cancer by inhibiting PI3K/Akt/mTOR and Hedgehog signalings

Keywords: فعالیت ضد تومور; Breast cancer; Drug design; Antitumor activity; PI3K; mTOR; Hedgehog;

دانلود رایگان متن کامل مقاله ISI 55 صفحه سال انتشار : 2017 سفارش ترجمه

Structure-based design and synthesis of imidazo[1,2-a]pyridine derivatives as novel and potent Nek2 inhibitors with in vitro and in vivo antitumor activities

Keywords: فعالیت ضد تومور; Nek2 inhibitors; Imidazo[1,2-a]pyridine; Antitumor activity; Selectivity; Nek2; NIMA-related kinase 2; Nlp; ninein-like protein; SAC; spindle assembly checkpoint; Mad1/2; mitotic arrest deficient 1/2; Hec1; highly expressed in cancer 1; CIN; chromosome in

دانلود رایگان متن کامل مقاله ISI 106 صفحه سال انتشار : 2017 سفارش ترجمه

Metabolism-based structure optimization: Discovery of a potent and orally available tyrosine kinase ALK inhibitor bearing the tetracyclic benzo[b]carbazolone core

Keywords: فعالیت ضد تومور; EML4-ALK kinase; Oxidative metabolism; Benzo[b]carbazolone; hERG; Antitumor activity;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

Effects of cultural medium on the formation and antitumor activity of polysaccharides by Cordyceps gunnii

Keywords: فعالیت ضد تومور; Cordyceps gunnii; Fermentation; Polysaccharide; Antitumor activity; Molecular weight distribution;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Synthesis and antitumor activity of ATB-429 derivatives containing a nitric oxide-releasing moiety

Keywords: فعالیت ضد تومور; VJRZZAUSRQHVAB-UHFFFAOYSA-N; FLTVEWINZQQISY-UHFFFAOYSA-N; NKSSHCIJJUSHTI-UHFFFAOYSA-N; FRXDVDHWFLUAMW-UHFFFAOYSA-N; PLQJDZREQJCQAP-UHFFFAOYSA-N; WAFAULTYESCLRC-UHFFFAOYSA-N; JXFQAABXOJURSK-UHFFFAOYSA-N; BTQLKFMADUDCQO-UHFFFAOYSA-N; LNVYUTKBSPJEOM-UHFFFAOY

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Study on the synthesis and biological activities of α-substituted arylacetates derivatives

Keywords: فعالیت ضد تومور; Arylacetates; Anisodamine; α-Glucosidase inhibitory activity; Antitumor activity; Hypoglycemic effect

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Synthesis, antitumor evaluation and molecular docking studies of [1,2,4]triazolo[4,3-b][1,2,4,5]tetrazine derivatives

Keywords: فعالیت ضد تومور; VQMBYCGKKNTCPS-UHFFFAOYSA-NTriazole; Tetrazine; X-ray diffraction; Antitumor activity; Docking study; Toxicity

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Investigation of antitumor mechanism of the chiral ruthenium complex Λ-[Ru(phen)2p-MOPIP]2 + in human gastric cancer MGC-803 cells

Keywords: فعالیت ضد تومور; Chiral ruthenium complexes; Antitumor activity; Telomerase inhibitor; Cell cycle arrest; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Synthesis, in vitro antitumor activity and molecular modeling studies of a new series of benzothiazole Schiff bases

Keywords: فعالیت ضد تومور; Benzothiazole; Schiff bases; Antitumor activity; Molecular modeling; In silico studies

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Photo-induced DNA cleavage and cytotoxicity of a ruthenium(II) arene anticancer complex

Keywords: فعالیت ضد تومور; Ruthenium anticancer complex; DNA cleavage; Phototoxicity; Antitumor activity; Comet assay; Photodynamic chemotherapy;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Structural identification and antitumor activity of the extracellular polysaccharide from Aspergillus terreus

Keywords: فعالیت ضد تومور; Aspergillus terreus; Extracellular polysaccharide; Structure; Antitumor activity;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Anti-tumor and immunomodulatory activities of an exopolysaccharide from Rhizopus nigricans on CT26 tumor-bearing mice

Keywords: فعالیت ضد تومور; Rhizopus nigricans; Exopolysaccharide; Immunomodulatory; Antitumor activity;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Synthesis, and docking studies of phenylpyrimidine-carboxamide derivatives bearing 1H-pyrrolo[2,3-b]pyridine moiety as c-Met inhibitors

Keywords: فعالیت ضد تومور; Phenylpyrimidine; 1H-Pyrrolo[2,3-b]pyridine; Synthesis; Docking; c-Met inhibitors; Antitumor activity

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Synthesis, characterization and biological studies on NiII and CuII complexes of two novel α,β-unsaturated 1,3-diketones related to curcuminoids

Keywords: فعالیت ضد تومور; α,β-Unsaturated 1,3-diketones; Curcuminoids; Antitumor activity; DNA binding; 1,7-Diarylheptanoids

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Toxicity and antitumor efficacy of Croton polyandrus oil against Ehrlich ascites carcinoma cells

Keywords: فعالیت ضد تومور; Antitumor activity; Croton polyandrous; Ehrlich ascites carcinoma; Essential oil; Genotoxicity; Toxicity;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه