دانلود مقالات ISI درباره AP، آپیکال + ترجمه فارسی

تحقیقات چند رشته ای در مورد قابلیت زیستی و فعالیت پپتیدهای پروتئین لوپین

A multidisciplinary investigation on the bioavailability and activity of peptides from lupin protein

Keywords: AP، آپیکال; Bioactive peptides; Caco-2 cells; HMGCoA reductase; Intestinal absorption; Lupinus albus; Plant proteinACE, angiotensin converting enzyme; AP, apical; APBS, adaptive Poisson–Boltzmann solver; BL, basolateral; DPP-IV, dipeptidyl peptidase IV; HMGCoAR, 3-hy

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Structure–activity relationships of dibenzoylhydrazines for the inhibition of P-glycoprotein-mediated quinidine transport

Keywords: AP، آپیکال; AP, apical; BL, basolateral; CNS, central nervous system; DBHs, dibenzoylhydrazines; DDI, drug–drug interactions; ESI, electrospray ionization; esp, electrostatic potential; FBS, fetal bovine serum; GA, Genetic Algorithm; HBSS, Hank’s balanced salt soluti

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Tuning the inflammatory response to silver nanoparticles via quercetin in Caco-2 (co-)cultures as model of the human intestinal mucosa

Keywords: AP، آپیکال; ACP, acid phosphatase; Ag-NPs, silver nanoparticles; ALP, alkaline phosphatase; AP, apical; BL, basolateral; CAT, catalase; DLS, dynamic light scattering; DMSO, dimethylsulfoxide; GIT, gastrointestinal tract; GR, glutathione reductase; GST, glutathione-S-

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Antitumour activity of EPA-enriched phospholipids liposomes against S180 ascitic tumour-bearing mice

Keywords: AP، آپیکال; AO, acridine orange; AP, apical; BL, basolateral; BW, body weight; CAT, catalase; DHA, docosahexaenoic acid; EB, ethidium bromide; EPA, eicosapentaenoic acid; GSH, glutathione; PL, phospholipids; PUFAs, polyunsaturated fatty acids; ROS, reactive oxygen sp

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Inhibitory effects of herbal constituents on P-glycoprotein in vitro and in vivo: Herb–drug interactions mediated via P-gp

Keywords: AP، آپیکال; AG, andrographolide; AP, apical; AUC, the area under the concentration–time curve; BL, basolateral; Cmax, the maximum plasma concentration; CMC, carboxymethylcellulose; CYP3A4, cytochrome P450 3A4; DAG, dehydroandrographolide; DDIs, drug–drug interactions

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

In vitro to in vivo evidence of the inhibitor characteristics of Schisandra lignans toward P-glycoprotein

Keywords: AP، آپیکال; HMs, herbal medicines; P-gp, P-glycoprotein; SLE, Schisandra lignans extract; DDI, drug–drug interaction; TBS-T, Tris-buffered saline-Tween 20; AP, apical; BL, basolateral; HBSS, Hank's balanced salt solution; AUC, the area under the concentration–time cu

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

A protocol for differentiation of human intestinal Caco-2 cells in asymmetric serum-containing medium

Keywords: AP، آپیکال; Foetal bovine serum; Basolateral medium; Serum reduction; Alkaline phosphatase; Permeability; Differentiation protocol; 3Rs; EnterocytesALP, alkaline phosphatase; AP, apical; BL, basolateral; FBS, foetal bovine serum; pNP, p-nitrophenol; pNPP, p-nitrophen

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

A protocol for in situ enzyme assays to assess the differentiation of human intestinal Caco-2 cells

Keywords: AP، آپیکال; ALP, alkaline phosphatase; ANPEP, alanyl (membrane) aminopeptidase; AP, apical; BL, basolateral; HRP, horseradish peroxidase; IAP, intestinal alkaline phosphatase; l-Ala-NA, l-alanine-p-nitroanilide; p-NP, p-Nitrophenol; p-NPP, p-Nitrophenyl phosphate; SU

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Bio-relevant media to assess drug permeability: Sodium taurocholate and lecithin combination or crude bile?

Keywords: AP، آپیکال; Ap, apical; Papp, apparent permeability coefficient; Bl, basolateral; BL, bile; BCS, Biopharmaceutical Classification System; DMEM, Dulbecco's modified Eagle medium; FaSSIF, fasted state simulated intestinal fluid; FeSSIF, fed state simulated intestinal f

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Co-cultures of enterocytes and hepatocytes for retinoid transport and metabolism

Keywords: AP، آپیکال; AP, apical; BC, β-carotene; BCMO1, β-carotene 15,15′-monooxygenase; BL, basolateral; CM, chylomicrons; FBS, fetal bovine serum; HPRT, human hypoxanthine phosphoribosyltransferase; RA, retinoic acid; RBP4, retinol binding protein 4; ROH, retinol; REs, reti

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Comparison of differing cytopathic effects in human airway epithelium of parainfluenza virus 5 (W3A), parainfluenza virus type 3, and respiratory syncytial virus

Keywords: AP، آپیکال; Ap, apical; BL, basolateral; BrdU, 5-bromo-2-deoxyuridine; CPE, cytopathic effect; EMCV, encephalomyocarditis virus; GFP, green fluorescent protein; HAE, human airway epithelial cells; H&E, hematoxylin and eosin; IFN, interferon; MOI, multiplicity of infe

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

The effects of excipients on transporter mediated absorption

Keywords: AP، آپیکال; ABC, ATP-binding cassette transporters; ADMET, absorption, distribution, metabolism, excretion, and toxicity; ACE, angiotensin-converting enzyme; AIDS, acquired immune deficiency syndrome; AMP, adenosine mono-phosphate; AP, apical; API, active pharmaceuti

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2010 سفارش ترجمه

Intracellular zinc stores protect the intestinal epithelium from Ochratoxin A toxicity

Keywords: AP، آپیکال; AP, apical; BCRP, breast cancer resistance protein; BL, basolateral; FCS, foetal calf serum; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; MTs, metallothioneins; MRP2, multidrug resistance protein 2; MTF-1, metal-specific transcription factor-1; OTA, o

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Pharmacokinetic characterization of ginsenoside Rh2, an anticancer nutrient from ginseng, in rats and dogs

Keywords: AP، آپیکال; AIC, Akaike’s Information Criterion; AP, apical; BL, basolateral; AUC, area under the plasma concentration–time curve; BCRP, breast cancer resistance protein; Css, the steady state average plasma level; CER, cumulative excretion rate; DF, degree of fluctu

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2009 سفارش ترجمه

Metabolism and transfer of the mycotoxin zearalenone in human intestinal Caco-2 cells

Keywords: AP، آپیکال; AP, apical; BL, basolateral; 5α-DHT, 5α-dihydrotestosterone; HBSS, Hank’s balanced salt solution; HPLC, high-performance liquid chromatography; HSD, hydroxysteroid dehydrogenase; Km, Michaelis constant; PBS, phosphate buffered saline; PGN, pregnenolone; T

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Permeability evaluation of peptidic HCV protease inhibitors in Caco-2 cells-correlation with in vivo absorption predicted in humans

Keywords: AP، آپیکال; HCV, hepatitis C virus; AUC, area under the curve; HPLC, high performance liquid chromatography; AP, apical; BL, basolateral; P-gp, P-glycoprotein; BCRP, breast cancer resistant proteinHCV protease inhibitor; In vivo and in vitro pharmacokinetics; Human p

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Effects of red wine on ochratoxin A toxicity in intestinal Caco-2/TC7 cells

Keywords: AP، آپیکال; AP, apical; BL, basolateral; BCRP, breast cancer resistance protein; MRP, multidrug resistance protein; OTA, ochratoxin A; TEER, trans-epithelial electrical resistance; TJ, tight junction; FCS, foetal calf serumMycotoxin; Caco-2; Claudin-4; Apoptosis; Tig

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Determination of CH330331, a novel 4-anilinoquinazoline inhibitor of epidermal growth factor receptor tyrosine kinase, in human Caco-2 monolayers by high performance liquid chromatography with ultraviolet detection: Application to a trans-epithelial trans

Keywords: AP، آپیکال; AP, apical; BCRP, breast cancer resistance protein; ANOVA, one-way analysis of variance; BL, basolateral; CV, coefficient of variation; EGFR, epidermal growth factor receptor; DMEM, Dulbecco's modified Eagle's medium; DMSO, dimethyl sulphoxide; HBSS, Hank

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Epithelial transport of deoxynivalenol: Involvement of human P-glycoprotein (ABCB1) and multidrug resistance-associated protein 2 (ABCC2)

Keywords: AP، آپیکال; ABC, ATPase binding cassette; AP, apical; BL, basolateral; BCRP, breast cancer resistance protein; 2-DOG, 2-deoxy-d-glucose; DON, deoxynivalenol; HBSS, Hank’s balanced salt solution; HPLC, high-performance liquid chromatography; MRP2, multidrug resistance

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Transepithelial transport of fusariotoxin nivalenol: Mediation of secretion by ABC transporters

Keywords: AP، آپیکال; ABC, ATPase binding cassette; AP, apical; BL, basolateral; BCRP, breast cancer resistance protein; 2-DOG, 2-deoxy-d-glucose; DAB, 3,3′-diaminobenzidine tetrahydrochloride; GCECD, gas-chromatography with electron capture detection; HBSS, Hank's balanced sa

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Flavonoid-mediated inhibition of intestinal ABC transporters may affect the oral bioavailability of drugs, food-borne toxic compounds and bioactive ingredients

Keywords: AP، آپیکال; Intestinal transcellular transport; ATP binding cassette (ABC) transport proteins; FlavonoidsABC, ATP binding cassette; ADP, adenine di-phosphate; AP, apical; ATP, adenine tri-phosphate; BCRP, breast cancer resistance protein; BL, basolateral; CYP, cytoch

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

Probiotics and Commensals Reverse TNF-α– and IFN-γ–Induced Dysfunction in Human Intestinal Epithelial Cells

Keywords: AP، آپیکال; Ap, apical; Bl, basolateral; BT, Bacteroides thetaiotaomicron; FS, fluorescein sulfonic acid; IFN-γ, interferon gamma; JAK, Janus kinase; PI3K, phosphatidylinositol 3-kinase; SOCS, suppressor of cytokine signaling; ST/LA, Streptococcus thermophilus and La

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2006 سفارش ترجمه