Luteolin, a flavonoid, inhibits AP-1 activation by basophils
Keywords: Basophils; Cytokines; Flavonoid; Luteolin; AP-1
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High-density lipoprotein is a potential growth factor for adrenocortical cells
Keywords: Adrenocortical cell; HDL; CLA-1; AP-1; PI3K; Akt
c-Jun activation is associated with proliferation and angiogenesis in invasive breast cancer
Keywords: c-Jun; AP-1; Immunohistochemistry; Angiogenesis; Proliferation; Breast cancer
Adapter protein NRBP associates with Jab1 and negatively regulates AP-1 activity
Keywords: NRBP, nuclear receptor binding protein; Jab1, Jun activation domain-binding protein 1; AP-1, activating protein-1NRBP; AP-1; Signal transduction; Jab1
Nicotinamide blocks N-methyl-N-nitrosourea-induced photoreceptor cell apoptosis in rats through poly (ADP-ribose) polymerase activity and Jun N-terminal kinase/activator protein-1 pathway inhibition
Keywords: apoptosis; AP-1; JNK; nicotinamide; N-methyl-N-nitrosourea; PARP; photoreceptor cell3-AB, 3-aminobenzamide; AP-1, activator protein-1; JNK/SAPK, Jun N-terminal kinase/stress-activated protein kinase; MNU, N-methyl-N-nitrosourea; NAD+, nicotinamide adenine
Interleukin-18 induces the production of vascular endothelial growth factor (VEGF) in rheumatoid arthritis synovial fibroblasts via AP-1-dependent pathways
Keywords: IL-18; VEGF; AP-1; Rheumatoid arthritis; Fibroblast-like synoviocytes
Activation of transcription factor AP-1 and mitogen-activated protein kinases in aniline-induced splenic toxicity
Keywords: Aniline; Oxidative stress; Spleen; MAPK; AP-1; TGF-β1;
Inhibition of ICAM-1 expression by garlic component, allicin, in gamma-irradiated human vascular endothelial cells via downregulation of the JNK signaling pathway
Keywords: Allicin; ICAM-1; Radiation; AP-1; JNK; HUVECs
Long term environmental tobacco smoke activates nuclear transcription factor-kappa B, activator protein-1, and stress responsive kinases in mouse brain
Keywords: Cigarette smoke; ROS; NF-κB; AP-1; Signal transduction
HIV-1 Nef stabilizes AP-1 on membranes without inducing ARF1-independent de novo attachment
Keywords: HIV-1; Nef; AP-1; ARF1;
Ageing introduces a complex pattern of changes in several rat brain transcription factors depending on gender and anatomical localization
Keywords: Cortex; Hippocampus; Aged rat; NFκB; AP-1; LXR; PPAR;
Effects of central injection of angiotensin-converting-enzyme inhibitor and angiotensin type 1 receptor antagonist on the brain NF-κB and AP-1 activities of rats given LPS
Keywords: Angiotensin II; LPS; IL-1; NF-κB; AP-1
Fludarabine induces pro-inflammatory activation of human monocytic cells through a MAPK/ERK pathway
Keywords: Fludarabine; Monocytes; MAPK/ERK; AP-1
Regulation of matrilysin expression in endothelium by fibroblast growth factor-2
Keywords: Endothelium; Matrilysin; MMP7; FGF-2; Stat1; Stat3; AP-1; Lef/Tcf;
Sources cellulaires des espèces réactives de l'oxygène et de l'azote
Keywords: Espèces réactives de l'oxygène; Espèces réactives de l'azote; Stress oxydant; Cellule; Facteurs de transcription; NF-KB; AP-1; Reactive oxygen/nitrogen species; Oxidative stress; Transcription factors; Nuclear factor-kappa B; Activator Protein-1;
Molecular regulation of an invasion-related molecule – options for tumour staging and clinical strategies
Keywords: Urokinase-receptor; Transcription; In vivo; AP-1; AP-2; Sp1; EMSA
Carboxylated chitooligosaccharides (CCOS) inhibit MMP-9 expression in human fibrosarcoma cells via down-regulation of AP-1
Keywords: AP-1; Activator protein-1; COS; Chitooligosaccharides; CCOS; Carboxylated chitooligosaccharides; ECM; Extracellular matrix; MMP; Matrix metalloproteinase; MTT; 3-(4,5-dimethyl-2-yl)-2,5-diphenyltetrazolium bromide; NF-κB; Nuclerfactor kappa B; PMA; Phorb
Tissue inhibitors of metalloproteinases-1 (TIMP-1) and -2(TIMP-2) are major serum factors that stimulate the TIMP-1 gene in human gingival fibroblasts
Keywords: Tissue inhibitor of metalloproteinases-1 (TIMP-1); TIMP-2; c-jun, c-fos and c-ets-1 mRNAs; AP-1; Human gingival fibroblasts (Gin-1 cells)
DNA binding activity of transcription factors in bronchial cells of horses with recurrent airway obstruction
Keywords: Asthma; AP-1; CEBP; CREB; GATA-3
Activation of transcriptional activities of AP-1 and SRE by a new zinc-finger protein ZNF641
Keywords: ZNF641; KRAB motif; Linker; Transcriptional suppressor; Heart development; MAPK signaling pathway; SRE; AP-1
Expression and regulation of the mu opioid peptide receptor in TPA-differentiated HL-60 promyelocytic leukemia cells
Keywords: HL-60; TPA; MOPR; AP-1; NFkB; Morphine
Inhibitory effect of curcumin on nitric oxide production from lipopolysaccharide-activated primary microglia
Keywords: Curcumin; Primary microglia; NO; iNOS; p38; JNK; NF-κB; AP-1
Mechanism of the cardioprotection of rhEPO pretreatment on suppressing the inflammatory response in ischemia–reperfusion
Keywords: Erythropoietin; Ischemia–reperfusion; NF-κB; AP-1; IL-10
Streptococcus pyogenes induces epithelial inflammatory responses through NF-κB/MAPK signaling pathways
Keywords: Streptococcus pyogenes; Chemokine; Cytokine; NF-κB; AP-1; MAP kinase
Identification and characterization of the Mustang promoter: Regulation by AP-1 during myogenic differentiation
Keywords: Mustang; Promoter; AP-1; C2C12; Differentiation; Musculoskeletal
Alteration of activator protein 1 DNA binding activity in gentamicin-induced hair cell degeneration
Keywords: aminoglycosides; immediate early genes; inner and outer hair cells; organ of Corti; signaling pathways; AP-1; activating protein-1; EMSA; electrophoretic-mobility-shift-assay; ERK; extracellular signal-related kinase; FBS; fetal bovine serum; FITC; fluore
Nuclear factor-kappa B nuclear translocation in the cochlea of mice following acoustic overstimulation
Keywords: Sensory systems; Auditory, vestibular, and lateral line: periphery; ABR; auditory brainstem response; AP-1; activator protein-1; Ca2+; calcium; EAA; excitory amino acid; EMSA; electrophoretic mobility shift assay; IHC; inner hair cell; iNOS; inducible nit
Sesquiterpene lactones as inhibitors of IL-8 expression in HeLa cells
Keywords: Sesquiterpene lactones; Interleukin-8; QSAR; Antiinflammatory activity; NFκB; AP-1
TNFα and GM-CSF-induced activation of the CAEV promoter is independent of AP-1
Keywords: CAEV; TNFα; GM-CSF; AP-1; Transcription
Glucocorticoid receptor β in acute and chronic inflammatory conditions: Clinical implications
Keywords: GCR β; Glucocorticoid receptor beta; Inflammation; Rheumatoid arthritis; SepsisAF, activation factor; AP-1; activator protein-1; DMARD, disease modifying antirheumatic drug; GC, glucocorticoid; GCR, GC receptor; GRE, GC response element; GRIP-1, GC recept
Both the basal transcriptional activity of the GADD45A gene and its enhancement after ionizing irradiation are mediated by AP-1 element
Keywords: GADD45A; AP-1; JunD; p53; Transcriptional regulation; Ionizing radiation
Helicobacter pylori Extract Induces Nuclear Factor-kappa B, Activator Protein-1, and Cyclooxygenase-2 in Esophageal Epithelial Cells
Keywords: AP-1; esophageal cancer; H pylori; HPE; NF-κB;
Molecular cloning and characterization of human Aph2 gene, involved in AP-1 regulation by interaction with JAB1
Keywords: hAph2; zf-DHHC; Yeast two-hybrid; JAB1; AP-1
Regulation of cocaine-induced activator protein 1 transcription factors by the extracellular signal-regulated kinase pathway
Keywords: addiction; striatum; gene expression; MAPK; AP-1; activator protein 1; CaPu; caudate putamen; CREB; cAMP/Ca2+ response element binding protein; DA; dopamine; EMSA; electromobility shift assay; ERK; extracellular signal-regulated kinase; IEG; immediate ear
2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induces matrix metalloproteinase (MMP) expression and invasion in A2058 melanoma cells
Keywords: TCDD; AhR; MMP; Melanoma; Invasion; AP-1
Peroxisome-proliferator-activated receptor-γ agonists inhibit the release of proinflammatory cytokines from RSV-infected epithelial cells
Keywords: Cytokines; Chemokines; A549 cells; RSV; NF-κB; AP-1; PPARγ; Ciglitazone; Troglitazone, 15d-PGJ2
Hypoxia protects HepG2 cells against etoposide-induced apoptosis VIA a HIF-1-independent pathway
Keywords: Hypoxia; HIF-1; AP-1; Apoptosis; Etoposide; Resistance; Cancer cells
Neuroprotection against ischemic brain injury by a small peptide inhibitor of c-Jun N-terminal kinase (JNK) via nuclear and non-nuclear pathways
Keywords: c-Jun N-terminal protein kinase; JNK; JNK interacting protein-1; JIP-1; Tat-JBD; cerebral ischemia/reperfusion; AP-1; activator-protein 1; BSA; bovine serum albumin; DTT; dithiothreitol; Fasl; Fas ligand; GluR6; glutamate receptor 6; h-DMEM; high-glucose
Selective cytotoxicity of ascochlorin in ER-negative human breast cancer cell lines
Keywords: Ascochlorin; AP-1; c-Jun; c-Fos; Fra-1; Breast cancer; ER; Apoptosis; Cytochrome c; Caspase;
c-Jun interacts with phospholipids and c-Fos at the interface
Keywords: PC; dilauroylphosphatidylcholine; PS; dilauroylphosphatidylserine; PIP2; phosphatidylinositoldiphosphate; Ï; surface lateral pressure; ÎV; surface potential; DTSP; dithiobis[succinimidylpropionate]; AP-1; c-Jun; Surface activity; Monolayers;
Transcriptional regulation of human CC chemokine CCL15 gene by NF-κB and AP-1 elements in PMA-stimulated U937 monocytoid cells
Keywords: Chemokine; CCL15; Leukotactin-1; NF-κB; AP-1; Transcription;
A δ2-Opioid Agonist Inhibits p38 MAPK and Suppresses Activation of Murine Macrophages
Keywords: inflammation; cytokines; NF-κB; AP-1; p38 MAPK;
Interleukin-12 p40 promoter activity is regulated by the reversible acetylation mediated by HDAC1 and p300
Keywords: HDAC1; p300; IL-12; C/EBPβ; Reversible acetylation; HAT; histone acetyltransferase; HDAC; histone deacetylase; IL-12; interleukin-12; C/EBPβ; CCAAT enhancer binding protein β; ChIP; chromatin immunoprecipitation; Co-IP; co-immunoprecipitation; AP-1; ac
Apoptosis signal-regulating kinase 1 in leukotriene D4-induced activator protein-1 activation in airway smooth muscle cells
Keywords: LTD4; ASK1; AP-1; Airway smooth muscle cells; Remodeling;
Inhibition of lipopolysaccharide-inducible nitric oxide synthase expression by acteoside through blocking of AP-1 activation
Keywords: AP-1; activator protein-1; cNOS; constitutive nitric oxide synthase; COX; cyclooxygenase; DMEM; Dulbecco's modified Eagle's medium; FCS; fetal calf serum; iNOS; inducible nitric oxide synthase; LPS; lipopolysaccharide; NF-κB; nuclear factor-κB; NO; nitr
PKCε induces interleukin-6 expression through the MAPK pathway in 3T3-L1 adipocytes
Keywords: PKC; IL-6; 3T3-L1 adipocyte; MEK; Elk-1; AP-1; Insulin resistance;
Overexpression of thioredoxin prevents thioacetamide-induced hepatic fibrosis in mice
Keywords: Thioredoxin; Hepatic fibrosis; Stellate cell; ADF; adult T cell leukemia-derived factor; ALT; alanine aminotransferase; AP-1; activator protein-1; AST; aspartate aminotransferase; CHX; cycloheximide; DMEM; Dulbecco's modified eagle medium; EB; Epstein-B
Differential regulation of the rat heme oxygenase-1 expression by Ets oncoproteins in glomerular mesangial cells
Keywords: AP-1; activating protein-1; bp; base pair; CAT; chloramphenicol acetytransferase; COL1A2; collagen type 1, alpha2; EBS; Ets binding site; HO; heme oxygenase; HSE; heat-shock element; GBM; glomerular basement membrane; NADPH; nicotinamide adenine dinucleot
Glycyrrhizin Induces Melanogenesis by Elevating a cAMP Level in B16 Melanoma Cells
Keywords: AP-1; glycyrrhizin; MAPK; melanogenesis; Ras; tyrosinase;
Molecular recognition of 15-deoxy-Δ12,14-prostaglandin J2 by nuclear factor-kappa B and other cellular proteins
Keywords: 15-Deoxy-Δ12,14-prostaglandin J2; Molecular recognition; Nuclear factor-kappa B; AP-1; p53; Thioredoxin; Docking; Electrostatic potentials