Keywords: APC، پروتئین فعال شده C; APC, activated protein C; CBP, cyclic-AMP regulatory element binding protein (CREB)-binding protein; DIC, disseminated intravascular coagulation; DRG, dorsal root ganglia; GAPDH, glyceraldehyde-3-phosphoate dehydrogenase; HAT, histone acetyltransferase; H
مقالات ISI APC، پروتئین فعال شده C (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: APC، پروتئین فعال شده C; Boswellic acid; Cancer; Molecular targets; Transcription factorsAKBA, 3-acetyl-11-keto-β-boswellic acid; APC, activated protein C; AR, androgen receptor; BA, beta-boswellic acid; BAX, BCL2-associated x protein; BC-4, boswellic acid acetate; BCDD, butyl 2-
Keywords: APC، پروتئین فعال شده C; AIS, acute ischemic stroke; aPC, activated protein C; ATC, acute traumatic coagulopathy; BBB, blood-brain barrier; CPB, cardiopulmonary bypass; DAMP, damage-associated molecular pattern; DIC, disseminated intravascular coagulation; FDP, fibrin/fibrinogen
Keywords: APC، پروتئین فعال شده C; AJs, adherent junctions; ANOVA, analysis of variance; APC, activated protein C; BBB, blood–brain barrier; EBI, early brain injury; ELISA, enzyme-linked immunosorbent assay; MRI, magnetic resonance imaging; PAR-1, protease-activated receptor-1; PBS, phosph
Do incident and recurrent venous thromboembolism risks truly differ between heterozygous and homozygous Factor V Leiden carriers? A retrospective cohort study
Keywords: APC، پروتئین فعال شده C; APC, Activated protein C; FVa, Factor FVa; PCR, Polymerase chain reaction; PE, Pulmonary embolism; VTE, Venous thromboembolismActivated protein C resistance; Factor V Leiden; Thrombophilia; Venous thrombosis; Pulmonary embolism
Determinants of acquired activated protein C resistance and D-dimer in breast cancer
Keywords: APC، پروتئین فعال شده C; APC, activated protein C; CAT, calibrated automated thrombogram; ETP, endogenous thrombin potential; F, factor; n-APC-sr, normalized APC sensitivity ratio; OR, odds ratio; SD, standard deviation; TF, tissue factor; TFPI, tissue factor pathway inhibitor; V
PAR-1 activation rescues astrocytes through the PI3K/Akt signaling pathway from chemically induced apoptosis that is exacerbated by gene silencing of β-arrestin 1
Keywords: APC، پروتئین فعال شده C; Akt, protein kinase B; APC, activated protein C; CINC, cytokine-induced neutrophil chemo attractant; JNK, c-jun N-terminal kinase; CNS, central nervous system; EGF, epidermal growth factor receptor; ERK, extracellular signal-regulated kinase; FCS, fetal c
The association of idiopathic recurrent pregnancy loss with polymorphisms in hemostasis-related genes
Keywords: APC، پروتئین فعال شده C; RPL, recurrent pregnancy loss; SERPINC1, antithrombin; THBD, thrombomodulin; TFPI, tissue factor pathway inhibitor; ANXA5, annexin A5; APC, activated protein C; SNP, single nucleotide polymorphism; OR, odds ratio; CI, confidence interval; BMI, body mass i
NF-κB-dependent and -independent pathways in the protective effects of activated protein C in hippocampal and cortical neurons at excitotoxicity
Keywords: APC، پروتئین فعال شده C; APC, activated protein C; EPCR, endothelial protein C receptor; PAR-1, protease-activated receptor-1; NF-κB, nuclear factor kappa B; AIF, apoptosis-inducing factor; p53, tumor suppressor protein p53Excitotoxicity; Helenalin; Apoptosis-inducing factor; Tum
TFPI resistance related to inherited or acquired protein S deficiency
Keywords: APC، پروتئین فعال شده C; TFPI, tissue factor pathway inhibitor; PS, protein S; NR, normalised ratio; dPT, diluted prothrombin time; aPC, activated protein C; PPP, platelet poor plasma; BSA, bovine serum albumin; TF, tissue factor; C4bBP, C4B binding protein; aPTT, activated parti
TFPI-dependent activities of Protein S
Keywords: APC، پروتئین فعال شده C; APC, activated protein C; K1/2/3, Kunitz domain 1/2/3; TFPI, full length tissue factor pathway inhibitor; TF, tissue factor; FVa/VIIa/VIIIa/Xa, factor Va/VIIa/VIIIa/XaTFPI; protein S; APC; anticoagulants
Fibrin clot properties in women heterozygous for factor V Leiden mutation: Effects of oral contraceptives
Keywords: APC، پروتئین فعال شده C; α2AP, α2-antiplasmin; aPC, activated protein C; BMI, body mass index; CLT, clot lysis time; CRP, C-reactive protein; F1 + 2, prothrombin fragments 1 + 2; FVL, factor V Leiden mutation; FVL(+/−), heterozygous carrier of FVL mutation; OC, oral contraceptive
Diversity of Human Plasma Protein C Inhibitor
Keywords: APC، پروتئین فعال شده C; PCI, protein C inhibitor; H-PCI, high molecular weight PCI; APC, activated protein C; DS, dermatan sulfate; STI, Soybean trypsin inhibitor; APMSF, (p-Amidinophenyl) methanesulfonyl fluoride hydrochlorideProtein C inhibitor; Dermatan sulfate; 2D-PAGE; Mass
Sepsis, thrombosis and organ dysfunction
Keywords: APC، پروتئین فعال شده C; APC, activated protein C; AT, antithrombin; DIC, disseminated intravascular coagulation; ECs, endothelial cells; EPCR, endothelial protein C receptor; HMGB-1, High Mobility Group Box-1; MODS, multiple organ dysfunction syndrome; PAI-1, plasminogen activat
Thrombomodulin-dependent effect of factor V Leiden mutation on the cross-linking of α2-plasmin inhibitor to fibrin and its consequences on fibrinolysis
Keywords: APC، پروتئین فعال شده C; α2-PI, α2-plasmin inhibitor; APC, activated protein C; APCE, antiplasmin cleaving enzyme; CPI, carboxypeptidase inhibitor; FVa, activated factor V; FVLeiden, factor V Leiden mutation; FXIII, factor XIII; FXIIIa, active factor XIII; FXIII-A, factor XIII A
Signaling of endothelial cytoprotection in transplantation
Keywords: APC، پروتئین فعال شده C; AP-1, activator protein-1; APC, activated protein C; Bcl-2, B cell lymphoma-2 protein; Bad, Bcl-2 antagonist of cell death; Bcl-xl, Bcl-extra long; CO, carbon monoxide; COX, cyclooxygenase; Cyt c, cytochrome c; Dll, Delta-like; EC, endothelial cell; eNOS,
A novel fibrinogenase from Agkistrodon acutus venom protects against DIC via direct degradation of thrombosis and activation of protein C
Keywords: APC، پروتئین فعال شده C; APC, activated protein C; APTT, activated partial thromboplastin time; AT-III, antithrombin III; DIC, disseminated intravascular coagulation; EGF, endothelial growth factor; FDP, fibrin(-ogen) degradation products; FIIa, fibrinogenase II from Agkistrodon
Functional characteristics of the novel, human-derived recombinant FVIII protein product, human-cl rhFVIII
Keywords: APC، پروتئین فعال شده C; APTT, activated partial thromboplastin time; ANOVA, analysis of variance; APC, activated Protein C; BDD, B-domain deleted; BHK, baby hamster kidney; BSA, bovine serum albumin; CHO, Chinese hamster ovary; ETP, endogenous thrombin potential; FVIII(a), (acti
A moderate aseptic local inflammation does not induce a significant systemic inflammatory response
Keywords: APC، پروتئین فعال شده C; Alb, albumin; ALT, alanine aminotransferase; AP, alkaline phosphatase; APC, activated protein C; aPTT, activated partial thromboplastin time; AT, antithrombin; CK, creatine kinase; Crea, creatinin; CRP, C-reactive protein; Eos, eosinophils; FVIII, factor
Enhanced induction of heme oxygenase-1 suppresses thrombus formation and affects the protein C system in sepsis
Keywords: APC، پروتئین فعال شده C; aPC, activated protein C; APTT, activated partial thromboplastin time; CLP, cecal ligation and perforation; CORM, CO-releasing molecule; DIC, disseminated intravascular coagulation; DMSO, dimethyl sulfoxide; ELISA, enzyme-linked immunosorbent assay; HE, h
The endothelial cell protein C receptor: Its role in thrombosis
Keywords: APC، پروتئین فعال شده C; PC, protein C; F, factor; APC, activated protein C; TM, thrombomodulin; EPCR, endothelial protein C receptor; TNF-α, tumor necrosis factor-α; PROCR, endothelial protein C receptor gene; aa, amino acid; UTR, untranslated region; sEPCR, soluble EPCR; TF, ti
The role of P4-P3’ residues flanking Arg336 in facilitating activated protein C-catalyzed cleavage and inactivation of factor VIIIa
Keywords: APC، پروتئین فعال شده C; APC, activated protein C; BHK, baby hamster kidney; HEPES, N-[2-hydroxyethyl] piperazine-N’-[2-ethanesulfonic acid]; SDS-PAGE, sodium dodecyl sulfate-polyacrylamide gel electrophoresis; ELISA, enzyme linked immunosorbent assayFactor VIII; Activated protei
Structure, function and pathophysiology of protease activated receptors
Keywords: APC، پروتئین فعال شده C; Protease; Protease activated receptor; PAR; GPCRAP, activating peptide; APC, activated protein C; ECL, extracellular loop; EGFR, epidermal growth factor receptor; EPCR, endothelial protein kinase C receptor; GPCR, G protein coupled receptor; HRS, hepatocy
A Novel Mutation (G2172→C) in the Factor V Gene in a Chinese Family with Hereditary Activated Protein C Resistance
Keywords: APC، پروتئین فعال شده C; APC-R, Activated protein C resistance; VTE, venous thromboembolism; FV, factor V; APC, activated protein C; AT, antithrombin; PC, protein C; PS, protein S; aPTT, activated partial thromboplastin time; ACL, anticardiolipin antibodies; LA, lupus anticoagula
Expression of protein C (PC), protein S (PS) and thrombomodulin (TM) in human colorectal cancer
Keywords: APC، پروتئین فعال شده C; ABC, avidin biotin complex technique; APC, activated protein C; CRC, colorectal cancer; EC(s), endothelial cell(s); EGF, epidermal growth factor; EPCR, endothelial cell protein C receptor; G, grade; IRS, immunoreactive score; MMP-2, gelatinase A, matrix m
A novel splice site mutation in intron C of PROS1 leads to markedly reduced mutant mRNA level, absence of thrombin-sensitive region, and impaired secretion and cofactor activity of mutant protein S
Keywords: APC، پروتئین فعال شده C; PS, protein S; Gla, γ-carboxyglutamic acid; TSR, thrombin-sensitive region; WT, wild-type; APC, activated protein C; EGF, epidermal growth factor; DVT, deep vein thrombosis; ELISA, enzyme-linked immunosorbent assay; moAb, monoclonal antibodyPROS1; protein
Calibrated automated thrombography demonstrates hypercoagulability in patients with idiopathic pulmonary arterial hypertension
Keywords: APC، پروتئین فعال شده C; APC, Activated Protein C; CAT, Calibrated Automated Thrombography; CI, Cardiac Index; CRP, C-Reactive Protein; CV, Coefficient of Variation; ETP, Endogenous Thrombin Potential; ETP-APC, ETP in presence of 25 nM of APC; F1.2, Prothrombin fragment 1.2; HBS,
Low level of factor V is associated with development of deep-vein thrombosis in Japanese patients
Keywords: APC، پروتئین فعال شده C; VTE, venous thromboembolism; DVT, deep vein thrombosis; APC, activated protein C; FV:Ag, factor V antigen; FV:PL-bound, phospholipid bound factor V; TTBS, Tween20 in TBS; TBS, tris-buffered salinedeep-vein thrombosis; factor V level; factor V antigen; pho
Dermatan sulfate: Recent structural and activity data
Keywords: APC، پروتئین فعال شده C; APC, activated protein C; BDNF, brain-derived growth factor; CS, chondroitin sulfate; DS, dermatan sulfate; FGF, fibroblast growth factor; GAGs, glycosaminoglycans; GDNF, glial-derived growth factor; GlcA, glucuronic acid; GalNAc, N-acetylgalactosamine; H
Coagulation activation and ultrasound characteristics in patients with carotid artery disease
Keywords: APC، پروتئین فعال شده C; AAA, Abdominal aortic aneurysm; ACE, Angiotensin converting enzyme; APC, Activated protein C; APC-PCI, Activated Protein C-Protein C Inhibitor complex; BMI, Body mass index; BP, Blood pressure; CAD, Coronary artery disease; COPD, Chronic obstructive pulmo
Activated protein C analog with reduced anticoagulant activity improves functional recovery and reduces bleeding risk following controlled cortical impact
Keywords: APC، پروتئین فعال شده C; TBI, traumatic brain injury; APC, activated protein C; PC, protein C; PAR-1, protease-activated receptor-1; EPCR, endothelial protein C receptor; BBB, blood brain barrier; CCI, controlled cortical impact; wt, wild-type; IP, intraperitoneal; PIB, pre-injur
Treatment of the critically ill patient with protein C: Is it worth the cost?
Keywords: APC، پروتئین فعال شده C; APACHE II, Acute Physiology and Chronic Heath Evaluation II; APC, activated protein C; APTT, Activated Partial Thromboplastin Time; ICU, intensive care unit; INR, International Normalized Ratio; SIRS, Systemic Inflammatory Response Syndrome; VOSL, value o
Thrombin and activated protein C inhibit the expression of secretory group IIA phospholipase A2 in the TNF-α-activated endothelial cells by EPCR and PAR-1 dependent mechanisms
Keywords: APC، پروتئین فعال شده C; sPLA2-IIA, secretory phospholipase A2 of group IIA; TNF-α, tumor necrosis factor alpha; PC, protein C; APC, activated protein C; PAR-1, protease-activated receptor-1; ELISA, enzyme-linked immunosorbent assay; EPCR, endothelial protein C receptor; HUVEC, h
Activated protein C levels in obesity and weight loss influence
Keywords: APC، پروتئین فعال شده C; BMI, Body mass index; WHR, waist hip ratio; VLCD, very low-calorie diet; APC, activated protein C; PC, protein C; PCI, protein C inhibitor; F1 + 2, fragment 1 + 2; EPCR, endothelial protein C receptor; T-chol, total cholesterol; TG, triglycerides; LDL-cho
A new chromogenic assay (HemosIL ThromboPath) is sensitive to major prothrombotic risk factors affecting the protein C pathway. Results of a multicenter study
Keywords: APC، پروتئین فعال شده C; APC, activated protein C; CI, confidence interval; CV, coefficient of variation; FV, (coagulation) factor V; FVIII, (coagulation) factor VIII; IU, international unit; LA, lupus anticoagulant; NPV, negative predictive value; OD, optical density; PC, protei
Thrombin generation and D-dimer concentrations in a patient cohort investigated for venous thromboembolism. Relations to venous thrombosis, factor V Leiden and prothrombin G20210A. The LIST study
Keywords: APC، پروتئین فعال شده C; APC, Activated Protein C; APCsr, Activated Protein C sensitivity ratio; AT-III, Antithrombin III; CT scan, Computed Tomography scan; DNA, Deoxyribonucleic Acid; DNTP, Deoxynucleotide Triphospate; DVT, Deep Vein Thrombosis; ETP, Endogenous Thrombin Potenti
The Pathologic Continuum of Diabetic Vascular Disease
Keywords: APC، پروتئین فعال شده C; glucose; atherosclerosis; advanced glycation end products; oxidative stress; inflammationAGE, advanced glycation end product; APC, activated protein C; CV, cardiovascular; EC, endothelial cell; ER, endoplasmic reticulum; PEDF, pigment epithelium-derived f
Clinical predictors of recurrent venous thromboembolism: A single institute experience in Korea
Keywords: APC، پروتئین فعال شده C; VTE, venous thromboembolism; DVT, deep vein thrombosis; PE, pulmonary embolism; APS, antiphospholipid syndrome; CMPD, chronic myeloproliferative disorders; PT, prothrombin; SLE, systemic lupus erythematosus; APC, activated protein C; IVC, inferior vena ca
Large-scale preparation of thrombin from human plasma
Keywords: APC، پروتئین فعال شده C; APC, activated protein C; DEAE, diethyl aminoethyl; ELISA, enzyme-linked immunoabsorbent assay; FXIII, Factor XIII (other coagulation factors are abbreviated in the same way); GFC, gel filtration chromatography; HIC, hydrophobic interaction chromatography
Treatment of endothelium with the chemotherapy agent vincristine affects activated protein C generation to a greater degree in newborn plasma than in adult plasma
Keywords: APC، پروتئین فعال شده C; APC, activated protein C; PC, protein C; α2M, α2macroglobulin; PCI, protein C inhibitor; α1AT, α1antitrypsin; EPCR, endothelial cell protein C receptor; TM, thrombomodulin; HUVEC, human umbilical vein endothelial cells.Thrombosis; Paediatric haemostasis;
Coagulation signalling following tissue injury: Focus on the role of factor Xa
Keywords: APC، پروتئین فعال شده C; ALI, acute lung injury; APC, activated protein C; ARDS, acute respiratory distress syndrome; BALF, bronchoalveolar lavage fluid; CTGF, connective tissue growth factor; COX-2, cyclo-oxygenase-2; EPR1, effector cell protease receptor 1; FVa, factor V (activ
Identification of a plasmin-interactive site within the A2 domain of the factor VIII heavy chain
Keywords: APC، پروتئین فعال شده C; APC, activated protein C; mAb, monoclonal antibody; EGR-factor IXa, Glu-Gly-Arg-active-site modified factor IXa; 6-AHA, 6-aminohexanoic acid; Ah-plasmin, anhydro-plasmin; wild-type A2, wt-A2; SPR-based assay, surface plasmon resonance-based assay; LRP, lo
Venous thromboembolism in carriers of the Factor V Leiden mutation and in patients without known thrombophilic risk factor; prediction of recurrence and APC–PCI complex concentration and/or soluble thrombomodulin antigen and activity
Keywords: APC، پروتئین فعال شده C; APC, activated protein C; PCI, protein C inhibitor; VTE, venous thromboembolism; s-TM, soluble thrombomodulin; DVT, deep vein thrombosis; FV, Factor V.APC–PCI complex concentration; s-TM activity; s-TM antigen; VTE patients; FV Leiden; VTE recurrence
Activation of protein C and hemodynamic recovery after coronary artery bypass surgery
Keywords: APC، پروتئین فعال شده C; 23; 25AMI, acute myocardial infarction; ANOVA, analysis of variance; APC, activated protein C; CABG, coronary artery bypass grafting; CI, cardiac index; CK-Mbm, mass of the Mb fraction of creatine kinase; CPB, cardiopulmonary bypass; ICU, intensive care u
Antithrombotic and anticoagulant effects of wild type and Gla-domain mutated human activated protein C in rats
Keywords: APC، پروتئین فعال شده C; WT, wild type; APC, activated protein C; PS, protein S; EPCR, endothelial protein C receptor; PAR, protease activated receptor; APTT, activated partial thromboplastin time; PT, prothrombin time; TBS, tris-buffered saline; BSA, bovine serum albumin; SDS-PA
Haplotype of thrombomodulin gene associated with plasma thrombomodulin level and deep vein thrombosis in the Japanese population
Keywords: APC، پروتئین فعال شده C; DVT, deep vein thrombosis; TM, thrombomodulin; PC, protein C; APC, activated protein C; PS, protein S; EGF, epidermal growth factor; SNP, single-nucleotide polymorphism; sTM, soluble TM; 5′-UTR, 5′-untranslated region; 3′-UTR, 3′-untranslated regionThromb
Clinical evaluation of a new functional test for detection of activated protein C resistance (Pefakit® APC-R Factor V Leiden) at two centers in Europe and the USA
Keywords: APC، پروتئین فعال شده C; APC, activated protein C; aPTT, activated partial thromboplastin time; CT, clotting time; DTI, direct thrombin inhibitor; DUMC, Duke University Medical Center; FRET, fluorescence resonance energy transfer; FV, factor V; FVa, activated FV; FVL, factor V Le
Evaluation and performance characteristics of the automated coagulation analyzer ACL TOP
Keywords: APC، پروتئین فعال شده C; Anti-FXa, anti-activated factor X; APC, activated protein C; aPTT, activated partial thromboplastin time; AT, antithrombin; CV, coefficient of variation; FV, (coagulation) factor V; FVIII, (coagulation) factor VIII; INR, international normalized ratio; OD
A novel therapeutic target in various lung diseases: Airway proteases and protease-activated receptors
Keywords: APC، پروتئین فعال شده C; APC, activated protein C; ASM, airway smooth muscle; CTGF, connective tissue growth factor; EGFR, epidermal growth factor receptor; HAT, human airway trypsin-like protease; HPAEC, human pulmonary artery endothelial cells; IL, interleukin; LPS, lipopolysac
Activated protein C resistance: The influence of ABO-blood group, gender and age
Keywords: APC، پروتئین فعال شده C; APC, Activated Protein C; APCR, Activated Protein C Resistance; APCR-APTT, APCR testing using APTT assay procedure; APCR-RVVT, APCR testing using RVVT assay procedure; APTT, Activated Partial Thromboplastin Time (assay); FVL, Factor V Leiden; GLV, GradiLe