Keywords: آپپرتیانت; Chemotherapy-induced nausea and vomiting; Carboplatin; NK1 receptor antagonist; Aprepitant; Fosaprepitant; Rolapitant; Systematic review; Meta-analysis;
مقالات ISI آپپرتیانت (ترجمه نشده)
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Keywords: آپپرتیانت; Aprepitant; Cancer chemotherapy; Solubility; Empirical models; Equation of state (EoS); Modeling;
Keywords: آپپرتیانت; Anti-emesis; Aprepitant; Chemotherapy; Cisplatin; Palonosetron
Keywords: آپپرتیانت; Confocal Raman spectroscopy; Dissolution mechanisms; Recrystallization; Aprepitant; Polymer; Solid dispersion;
Keywords: آپپرتیانت; Aprepitant; c-Fos; Emesis; Kaolin; Tachykinin NK1 receptor; Tranexamic acid; Chemical compounds studied in this article; Aprepitant (PubChem CID: 151165); Domperidone (PubChem CID: 3151); Ondansetron (PubChem CID: 68647); Tranexamic acid (PubChem CID: 552
Keywords: آپپرتیانت; AUC; area under the curve; API; active pharmaceutical ingredient; CYP; cytochrome P450; BCS; biopharmaceutical classification system; FaSSIF/FeSSIF; fasted/fed state stimulating intestinal fluid; PAMPA; parallel artificial membrane permeation assay; SDS;
Keywords: آپپرتیانت; Aprepitant; Antiemetic; Highly emetogenic chemotherapy; Moderately emetogenic chemotherapy; Chemotherapy-induced nausea and vomiting;
Keywords: آپپرتیانت; aprepitant; postoperative nausea and vomiting; neurokinin-1 receptor; antiemetic therapy; review
Pruritus in Cutaneous T-Cell Lymphoma and Its Management
Keywords: آپپرتیانت; Cutaneous T-cell lymphoma; Interleukins; Pruritus; Substance P; Antidepressants; Histone deacetylase inhibitors; Aprepitant; Visual analog scale;
Neurokinin-1 receptor (NK1R) inhibition sensitizes APL cells to anti-tumor effect of arsenic trioxide via restriction of NF-κB axis: Shedding new light on resistance to Aprepitant
Keywords: آپپرتیانت; Acute leukemia; Aprepitant; Neurokinin-1 receptor; Arsenic trioxide; NF-κB;
Addition of 3-day aprepitant to ondansetron and dexamethasone for prophylaxis of chemotherapy-induced nausea and vomiting among patients with diffuse large B cell lymphoma receiving 5-day cisplatin-based chemotherapy
Keywords: آپپرتیانت; Aprepitant; Lymphoma; Multi-day cisplatin; Nausea; Vomiting;
Efficacy of aprepitant for CHOP chemotherapy-induced nausea, vomiting, and anorexia
Keywords: آپپرتیانت; Aprepitant; CHOP chemotherapy; CINV; Substance P; Malignant lymphoma;
Production of aprepitant nanocrystals by wet media milling and subsequent solidification
Keywords: آپپرتیانت; Wet media milling; Nanocrystals; Aprepitant; Nanosuspensions; Stabilizers; Crystal polymorphism; Spray-drying; Freeze-drying;
Incidence of chemotherapy-induced nausea and vomiting associated with docetaxel and cyclophosphamide in early breast cancer patients and aprepitant efficacy as salvage therapy. Results from the Spanish Breast Cancer Group/2009-02 study
Keywords: آپپرتیانت; Early breast cancer; Antiemesis; Docetaxel-cyclophosphamide; Aprepitant; CINV;
Evaluation of Pentravan®, Pentravan® Plus, Phytobase®, Lipovan® and Pluronic Lecithin Organogel for the transdermal administration of antiemetic drugs to treat chemotherapy-induced nausea and vomiting at the hospital
Keywords: آپپرتیانت; Apt; aprepitant; Dex; dexamethasone; MAPE; mean absolute percentage error; Ond; ondansetron; Pent; Pentravan®; Pent+; Pentravan® Plus; Phyt; Phytobase®; Lipo; Lipovan®; PLO; Pluronic Lecithin Organogel; Ondansetron; Dexamethasone; Aprepitant; Transder
Inhibition of tachykinin NK1 receptor using aprepitant induces apoptotic cell death and G1 arrest through Akt/p53 axis in pre-B acute lymphoblastic leukemia cells
Keywords: آپپرتیانت; Acute lymphoblastic leukemia; Aprepitant; P53; Nalm-6 cells; Tachykinin NK1 receptor;
Combination antiemetic therapy with aprepitant/fosaprepitant in patients with colorectal cancer receiving oxaliplatin-based chemotherapy (SENRI trial): A multicentre, randomised, controlled phase 3 trial
Keywords: آپپرتیانت; Aprepitant; Oxaliplatin; Moderately emetogenic chemotherapy; Antiemetics;
Aprepitant in patients with advanced non-small-cell lung cancer receiving carboplatin-based chemotherapy
Keywords: آپپرتیانت; Antiemetic; Aprepitant; Carboplatin; Chemotherapy-induced nausea and vomiting; Non-small-cell lung cancer; Pemetrexed
Antagonism of substance P and perception of breathlessness in patients with chronic obstructive pulmonary disease
Keywords: آپپرتیانت; Aprepitant; Substance P; Beta-endorphin; Resistive load breathing; Chronic obstructive pulmonary disease
Characterization of a robust anti-Prelog short-chain dehydrogenase/reductase ChKRED20 from Chryseobacterium sp. CA49
Keywords: آپپرتیانت; Bioreduction; Ketone reductase; Short-chain dehydrogenase/reductase; anti-Prelog; Aprepitant
Identification of ketone reductase ChKRED20 from the genome of Chryseobacterium sp. CA49 for highly efficient anti-Prelog reduction of 3,5-bis(trifluoromethyl)acetophenone
Keywords: آپپرتیانت; Ketone reductase; Short-chain dehydrogenase; anti-Prelog; Aprepitant; Asymmetric bioreduction
Research ArticleHepatoblastoma cells express truncated neurokinin-1 receptor and can be growth inhibited by aprepitant in vitro and in vivo
Keywords: آپپرتیانت; Neurokinin-1 receptor (NK1R); Aprepitant; Substance P (SP); Anti-tumor target; Xenograft; Apoptosis; Hepatoblastoma (HB);
Long-Acting Serotonin Antagonist (Palonosetron) and the NK-1 Receptor Antagonists
Keywords: آپپرتیانت; Postoperative; Postdischarge; Nausea; Vomiting; Palonosetron; Aprepitant; Casopitant; Rolapitant;
Molecular mechanisms of 5-HT3 and NK1 receptor antagonists in prevention of emesis
Keywords: آپپرتیانت; Ondansetron; Granisetron; Dolasetron; Tropisetron; Palonosetron; Aprepitant; Netupitant; 5-HT3 receptor; NK1 receptor
Efficacy of aprepitant among patients aged 65 and over receiving moderately to highly emetogenic chemotherapy: A meta-analysis of unpublished data from previously published studies
Keywords: آپپرتیانت; Aprepitant; Elderly; Meta-analysis; Antiemetic; Nausea; Vomiting; Chemotherapy
Prevention of Nausea and Vomiting Associated with Stem Cell Transplant: Results of a Prospective, Randomized Trial of Aprepitant Used with Highly Emetogenic Preparative Regimens
Keywords: آپپرتیانت; Aprepitant; Nausea; Vomiting; Stem cell transplantation; Antiemetics; Phase III trial;
Determination of eight isomers and related substance of Aprepitant using normal-phase and reverse-phase HPLC methods with mass spectrophotometric detection
Keywords: آپپرتیانت; Aprepitant; Chiral separation; Related substances; HPLC; Mass spectrophotometer;
The substance P/neurokinin-1 receptor system in lung cancer: Focus on the antitumor action of neurokinin-1 receptor antagonists
Keywords: آپپرتیانت; Apoptosis; Aprepitant; L-732,138; L-733,060; Non-small cell lung cancer; Small cell lung cancer
Aprepitant for Patients Receiving Highly Emetogenic Chemotherapy: An Economic Analysis for Singapore
Keywords: آپپرتیانت; aprepitant; chemotherapy; cost-effectiveness; emesis; Singapore
In vitro and in vivo pharmacological characterization of the novel NK1 receptor selective antagonist Netupitant
Keywords: آپپرتیانت; Netupitant; Aprepitant; Calcium mobilization; Guinea pig ileum; Mice; Gerbils;
Korean red ginseng extract ameliorates skin lesions in NC/Nga mice: An atopic dermatitis model
Keywords: آپپرتیانت; KRG; Korean red ginseng; AD; atopic dermatitis; Treg; regulatory T or T regulatory; TNF; tumor necrosis factor; Th2; T helper 2 type; LC; Langerhans cell; Th1; T helper 1 type; TNCB; trinitrochlorobenzene; PGP 9.5; protein gene product 9.5; PFA; paraforma
Actualités dans les traitements antiémétiques
Keywords: آپپرتیانت; Nausées; Vomissements postopératoires; Antagonistes du récepteur de la neurokinine 1 (AR-NK1); Aprépitant; Postoperative nausea; Vomiting; Neurokinin 1 receptor antagonists; Aprepitant;
Forecasting in vivo oral absorption and food effect of micronized and nanosized aprepitant formulations in humans
Keywords: آپپرتیانت; Aprepitant; Micronization; Nanosizing; Biorelevant dissolution testing; In silico simulation; Absorption modeling
S41744, a dual neurokinin (NK)1 receptor antagonist and serotonin (5-HT) reuptake inhibitor with potential antidepressant properties: A comparison to aprepitant (MK869) and paroxetine
Keywords: آپپرتیانت; Neurokinin1 receptor;; Substance P;; Serotonin transporter;; Aprepitant;; Antidepressant;; Paroxetine
Safety and efficacy of a triple antiemetic combination with the NK-1 antagonist aprepitant in highly and moderately emetogenic multiple-day chemotherapy
Keywords: آپپرتیانت; Aprepitant; CINV; Multiple-day chemotherapy; Dexamethasone; Granisetron
A sensitive and rapid liquid chromatography-tandem mass spectrometry method for the quantification of the novel neurokinin-1 receptor antagonist aprepitant in rhesus macaque plasma, and cerebral spinal fluid, and human plasma with application in translati
Keywords: آپپرتیانت; Aprepitant; Liquid chromatography-tandem mass spectrometry; Translational research; Cerebral spinal fluid; Plasma;
The tachykinin NK3 receptor agonist senktide induces locomotor activity in male Mongolian gerbils
Keywords: آپپرتیانت; Gerbil; Senktide; Neurokinin; Tachykinin; Locomotor activity; Talnetant; SB223412; Osanetant; SR142801; SB222200; MK869; Aprepitant; Antipsychotic
Role of tachykinin NK1 and NK2 receptors in colonic sensitivity and stress-induced defecation in gerbils
Keywords: آپپرتیانت; Aprepitant; Saredutant; Colorectal distension; Stress; Visceral pain; Tachykinin; NK receptor; Gerbil; Colonic motility
Health outcomes and cost-effectiveness of aprepitant in outpatients receiving antiemetic prophylaxis for highly emetogenic chemotherapy in Germany
Keywords: آپپرتیانت; Antiemetic prophylaxis; Aprepitant; Chemotherapy-induced nausea and vomiting; Cost-effectiveness analysis; Health outcomes
Single-dose aprepitant vs ondansetron for the prevention of postoperative nausea and vomiting: a randomized, double-blind Phase III trial in patients undergoing open abdominal surgeryâ
Keywords: آپپرتیانت; aprepitant; clinical trials; PONV; ondansetron; serotonin (5-hydroxy-tryptamine), antagonism;
An HPLC chromatographic reactor approach for investigating the hydrolytic stability of a pharmaceutical compound
Keywords: آپپرتیانت; On-column reaction; Degradation kinetics; HPLC; Chromatographic reactor; Aprepitant; Fosaprepitant Dimeglumine; Emend; Stability testing
Lack of Efficacy of the Substance P (Neurokinin1 Receptor) Antagonist Aprepitant in the Treatment of Major Depressive Disorder
Keywords: آپپرتیانت; Substance P; neurokinin1; aprepitant; depression; clinical trial; positron emission tomography
The oral NK1 antagonist aprepitant for the prevention of acute and delayed chemotherapy-induced nausea and vomiting: Pooled data from 2 randomised, double-blind, placebo controlled trials
Keywords: آپپرتیانت; Aprepitant; NK1 antagonist; Antiemetic; Nausea; Vomiting; Clinical trial;