Specific deletion connexin43 in astrocyte ameliorates cognitive dysfunction in APP/PS1 mice
Keywords: آستروسیت; Alzheimer's disease; Astrocyte; Connexin43; APP/PS1 mice;
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Inhibitors of the NMDA-Nitric Oxide Signaling Pathway Protect Against Neuronal Atrophy and Synapse Loss Provoked by l-alpha Aminoadipic Acid-treated Astrocytes
Keywords: آستروسیت; 2-DG; 2-deoxy-d-glucose; ANOVA; analyses of variance; ATP; Adenosine tri-phosphate; cDMEM; complete Dulbecco's Modified Eagle Medium; cDNA; complementary deoxyribonucleic acid; CM; conditioned media; cNBM; complete neurobasal A medium; CNS; central nerv
Megalencephalic leukoencephalopathy with subcortical cysts: A personal biochemical retrospective
Keywords: آستروسیت; Leukodystrophy; MLC1; GlialCAM; ClC-2; Astrocyte;
Reduced post-stroke glial scarring in the infant primate brain reflects age-related differences in the regulation of astrogliosis
Keywords: آستروسیت; Neocortex; Brain injury; Marmoset; Astrocyte; Regeneration;
Glia- and tissue-specific changes in the Kynurenine Pathway after treatment of mice with lipopolysaccharide and dexamethasone
Keywords: آستروسیت; Astrocyte; Microglia; Inflammation; Stress; Kynurenine;
Non-cell-autonomous actions of α-synuclein: Implications in glial synucleinopathies
Keywords: آستروسیت; Astrocyte; Microglia; Neurodegeneration; Neuroinflammation; Parkinson disease; Protein aggregation; Multiple system atrophy; AD; Alzheimer disease; CJD; Creutzfeldt-Jakob disease; CNP; 3â²-cyclic nucleotide 3â²-phosphodiesterase; CSF; cerebrospinal fl
Astroglial correlates of neuropsychiatric disease: From astrocytopathy to astrogliosis
Keywords: آستروسیت; Astrocyte; GFAP; Depression; Schizophrenia; Addiction;
Research articleInhibitions of PKC and CaMK-II synergistically rescue ischemia-induced astrocytic dysfunction
Keywords: آستروسیت; Ischemia; Astrocyte; Glutamate transporter; PKC and CaMK-II;
HTLV-1 induces a Th1-like state in CD4+Â CCR4+ T cells that produces an inflammatory positive feedback loop via astrocytes in HAM/TSP
Keywords: آستروسیت; HAM; HTLV-1; CCR4; CXCR3; CXCL10; Astrocyte;
Astrocytes regulate the expression of Sp1R3 on oligodendrocyte progenitor cells through Cx47 and promote their proliferation
Keywords: آستروسیت; Oligodendrocyte progenitor cell; Astrocyte; Connexin 47; Sphingosine-1-phosphate receptors 3; Proliferation;
Evaluating the role of astrocytes on β-estradiol effect on seizures of Pilocarpine epileptic model
Keywords: آستروسیت; Pilocarpine (PubChem CID: 5910); Atropine Sulfate (PubChem CID: 5927); Beta-estradiol (PubChem CID: 5757); Lithium Chloride (PubChem CID: 433294); Diazepam (PubChem CID: 3016); Epilepsy; Astrocyte; β-estradiol; Glutamine synthetase; GLT-1 transporter;
Research reportInhibition of platelet-derived growth factor receptor β reduces reactive glia and scar formation after traumatic brain injury in mice
Keywords: آستروسیت; Traumatic brain injury; Scar formation; Regeneration; PDGFRβ, p-PDGFRβ; AG1296; Astrocyte;
Inhibition of miR-181a protects female mice from transient focal cerebral ischemia by targeting astrocyte estrogen receptor-α
Keywords: آستروسیت; MicroRNA; Astrocyte; Ischemia-reperfusion injury; MCAO; Stroke; Estrogen;
Astrocyte contributes to pain development via MMP2-JNK1/2 signaling in a mouse model of complex regional pain syndrome
Keywords: آستروسیت; Chronic post-ischemia pain; Spinal cord; Astrocyte; c-jun N-terminal kinase; Matrix metalloproteinase-2;
Research PaperAltered gene expression profile in a mouse model of SCN8A encephalopathy
Keywords: آستروسیت; RNA-seq; Transcriptome; Seizure; Epileptic encephalopathy; Astrocyte; Gene expression; Sodium channel;
NADPH oxidase-derived H2O2 mediates the regulatory effects of microglia on astrogliosis in experimental models of Parkinson's disease
Keywords: آستروسیت; BDNF; brain derived neurotrophic factor; GDNF; glia derived neurotrophic factor; GFAP; glial fibrillary protein; Iba-1; ionized calcium binding adaptor molecule 1; IL-1β; interleukin-1β; LPS; lipopolysaccharide; LME; l-leucine-methyl esther; MAPK; mitog
GABAÏ selective antagonist TPMPA partially inhibits GABA-mediated currents recorded from neurones and astrocytes in mouse striatum
Keywords: آستروسیت; Astrocyte; GABA-A receptors; GABAÏ; Interneurons; Neostriatum; (1, 2, 5, 6-Tetrahydropyridine-4-yl)methylphosphinic acid (TPMPA) (PubChem CID:5520); 6-Cyano-7-nitroquinoxaline-2,3-diolate (CNQX) (PubChem CID:6093155); (2R)-2-Amino-5-phosphonopentanoic ac
Research PaperMutation of the caspase-3 cleavage site in the astroglial glutamate transporter EAAT2 delays disease progression and extends lifespan in the SOD1-G93A mouse model of ALS
Keywords: آستروسیت; Excitotoxicity; Glutamate; Astrocyte; Amyotrophic lateral sclerosis; EAAT2; GLT-1; SOD1;
Characterization of aromatase expression in the spinal cord of an animal model of familial ALS
Keywords: آستروسیت; Aromatase; SOD1-G93A transgenic mouse; Astrocyte; Amyotrophic lateral sclerosis; Spinal cord;
Analysis of the expression of the Wnt family of proteins and its modulatory role on cytokine expression in non activated and activated astroglial cells
Keywords: آستروسیت; CNS; central nervous system; BBB; blood brain barrier; Fz; Frizzled; ROR; receptor tyrosine kinase-like orphan receptor; PTK7; protein tyrosine kinase 7; PCP; planar cell polarity; Wif; Wnt inhibitory factor; Dkk; Dickkopf; sFRP; secreted Frizzled-related
Time-course of glial changes in the hyperhomocysteinemia model of vascular cognitive impairment and dementia (VCID)
Keywords: آستروسیت; AD; Alzheimer's disease; AQP4; aquaporin 4 water channel; CAA; cerebral amyloid angiopathy; HHcy; hyperhomocysteinemia; MMP9; Matrix metalloproteinase 9; VCID; vascular cognitive impairment and dementia; neuroinflammation; astrocyte; dementia; cerebrova
Localization of a mutant SOD1 protein in E40K-heterozygous dogs: Implications for non-cell-autonomous pathogenesis of degenerative myelopathy
Keywords: آستروسیت; Canine; Animal model; Degenerative myelopathy; Astrocyte; Amyotrophic lateral sclerosis; Superoxide dismutase 1;
27-Hydroxycholesterol regulates cholesterol synthesis and transport in C6 glioma cells
Keywords: آستروسیت; 27-hydroxycholesterol; Cholesterol; Synthesis; Transport; Brain; Astrocyte;
Original articlePPP1CC is associated with astrocyte and microglia proliferation after traumatic spinal cord injury in rats
Keywords: آستروسیت; Spinal cord injury; Protein phosphatase 1; Catalytic subunit; Gamma isozyme (PPP1CC); Astrocyte; Microglia; Proliferation; Rats;
Rapamycin-Sensitive Late-LTP is Enhanced in the Hippocampus of IL-6 Transgenic Mice
Keywords: آستروسیت; ANOVA; analysis of variance; ACSF; artificial cerebral-spinal fluid; CNS; central nervous system; DNA; deoxyribonucleic acid; ERK; extracellularly regulated kinase; fEPSP; field excitatory postsynaptic potential; HFS; high-frequency stimulation; I/O; inpu
Differential modulation of glial cell mediated neuroinflammation in Plasmodium berghei ANKA infection by TGF β and IL 6
Keywords: آستروسیت; Plasmodium berghei ANKA; Astrocyte; Microglia; Transforming growth factor β; Interleukin 6; Neuroinflammation;
Astrocytes modulate thalamic sensory processing via mGlu2 receptor activation
Keywords: آستروسیت; Astrocyte; Metabotropic glutamate receptor subtype 2; Synaptic inhibition; Thalamus; Thalamic reticular nucleus; AMPA; α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; CNQX; 6-cyano-7-nitroquinoxaline-2,3-dione; DL-APV; DL-2-Amino-5-phosphonopentano
ReviewExploring the Ca2+-dependent synaptic dynamics in vibro-dissociated cells
Keywords: آستروسیت; Synaptic strength; Receptor trafficking; Quantal synaptic current; Astrocyte; Vesicular release; ATP receptor; NMDA receptor; Single-synapse response;
Regular articleThe expression and activity of KV3.4 channel subunits are precociously upregulated in astrocytes exposed to Aβ oligomers and in astrocytes of Alzheimer's disease Tg2576 mice
Keywords: آستروسیت; Astrocyte; KV3.4 potassium channel; Alzheimer's disease; Aβ-oligomers; Aβ1-42; GFAP; Tg2576;
The Ï1 receptor regulates accumulation of GM1 ganglioside-enriched autophagosomes in astrocytes
Keywords: آستروسیت; Ï1R; sigma (Ï)-1 receptor; Aβ; amyloid β-protein; AD; alzheimer disease; APP; amyloid precursor protein; CTX-HRP; Horseradish peroxidase-cholera toxin B subunit; DMEM; Dulbecco's modified Eagle's medium; DR; dopamine receptor; DRMs; detergent-resi
Research PaperThe role of spinal interleukin-1β and astrocyte connexin 43 in the development of mirror-image pain in an inflammatory pain model
Keywords: آستروسیت; Mirror-image pain; Interleukin-1Ã; Astrocyte; Connexin 43;
HYP-17, a novel voltage-gated sodium channel blocker, relieves inflammatory and neuropathic pain in rats
Keywords: آستروسیت; Sodium channel inhibitor; Spinal cord injury; Tail nerve injury; Neuropathic pain; Microglia; Astrocyte;
BMP7 expression in the adult rat brain
Keywords: آستروسیت; Astrocyte; Neuron; Immunohistochemistry; BMP; bone morphogenetic protein; BMPR; bone morphogenetic protein receptor; BSA; bovine serum albumin; CNS; central nervous system; CSPGs; chondroitin sulfate proteoglycans; GFAP; glial fibrillary acidic protein; I
Effect of the 5α-reductase enzyme inhibitor dutasteride in the brain of intact and parkinsonian mice
Keywords: آستروسیت; 3α-diol; 5α-androstane-3α, 17β-diol; 3β-diol; 5α-androstane-3β, 17β-diol; 5-HIAA; 5-hydroxyindoleacetic acid; 5-HT; serotonin; DA; dopamine; DAT; dopamine transporter; DHEA; dehydroepiandrosterone; DHP; 5α-dihydroprogesterone; DHT; dihydrotestost
Nrf2 pathway activation upon rotenone treatment in human iPSC-derived neural stem cells undergoing differentiation towards neurons and astrocytes
Keywords: آستروسیت; Neural stem cells; Rotenone; Nrf2 pathway; Astrocyte; Dopaminergic neurons; Neurite length; Neurotoxicity; AOP; Adverse Outcome Pathway; ARE; Antioxidant-Responsive-Element; DA; Dopaminergic; DIV; days in vitro; GABA; Gamma-Aminobutyric Acid; GABRA1; Gam
IL-17 signalling in astrocytes promotes glutamate excitotoxicity: Indications for the link between inflammatory and neurodegenerative events in multiple sclerosis
Keywords: آستروسیت; IL-17A; Multiple sclerosis; Astrocyte; Glutamate transporter; Glutamine synthetase; Glutamate exocytosis; Glutamate excitotoxicity;
Hemoglobin pretreatment endows rat cortical astrocytes resistance to hemin-induced toxicity via Nrf2/HO-1 pathway
Keywords: آستروسیت; Oxidative stress; Heme oxygenase 1; Nuclear transcription factor-erythroid 2 related factor; Intracerebral hemorrhage; Astrocyte;
Treatment of rats with the JAK-2 inhibitor fedratinib does not lead to experimental Wernicke's encephalopathy
Keywords: آستروسیت; Vitamin B1; Thiamine deficiency; Myelofibrosis; Astrocyte; Neurodegeneration; Excitotoxicity;
Immunohistochemical comparison of astrocytic mGluR5 upregulation in infraorbital nerve- versus sciatic nerve-ligated rat
Keywords: آستروسیت; Neuropathic pain; Trigeminal nucleus; Spinal cord; mGluR5 receptor; Astrocyte; Neuroinflammation;
Astroglial calcium signalling in Alzheimer's disease
Keywords: آستروسیت; Neuroglia; Alzheimer's disease; Astrocyte; Calcium signalling; InsP3 receptors; Glutamate receptors; β-amyloid; Astrogliosis; Astroglial atrophy;
Acute liver failure is associated with altered cerebral expression profiles of long non-coding RNAs
Keywords: آستروسیت; Liver disease; Fulminant hepatic failure; Azoxymethane; Hepatic encephalopathy; Astrocyte; Molecular signaling; Brain edema;
Astroglial Ca2+ signaling is generated by the coordination of IP3R and store-operated Ca2+ channels
Keywords: آستروسیت; Astrocyte; Ca2+ signal; SOC channel; IP3 receptor; Endoplasmic reticulum;
Ceftriaxone-mediated upregulation of the glutamate transporter GLT-1 contrasts neurotoxicity evoked by kainate in rat organotypic spinal cord cultures
Keywords: آستروسیت; Excitotoxicity; Astrocyte; β-lactam antibiotic; Glutamate uptake blocker; Neuroprotection; Motoneuron;
Ginsenoside Rg1 alleviates corticosterone-induced dysfunction of gap junctions in astrocytes
Keywords: آستروسیت; Depression; Ginsenoside Rg1; Astrocyte; Gap junction; Cx43;
Overexpression of Mitofusin2 decreased the reactive astrocytes proliferation in vitro induced by oxygen-glucose deprivation/reoxygenation
Keywords: آستروسیت; Mitofusin2; Astrocyte; Ischemiaï¼Proliferation; Cell-cycle; Ras-p-Raf1-p-ERK1/2;
TDP-43 proteolysis is associated with astrocyte reactivity after traumatic brain injury in rodents
Keywords: آستروسیت; ALS; Amyotrophic lateral sclerosis; ANOVA; A two-way analysis of variance; FTLD; Frontotemporal lobar degeneration; GFAP; Glial fibrillary acidic protein; TBI; Traumatic brain injury; TDP-43; Transactivation response DNA-binding protein 43; TX; High-salt
Glial and tissue-specific regulation of Kynurenine Pathway dioxygenases by acute stress of mice
Keywords: آستروسیت; Stress; Ido; Tdo; Kynurenine; Astrocyte; Liver;
Transcriptional regulation of Nfix by NFIB drives astrocytic maturation within the developing spinal cord
Keywords: آستروسیت; Nuclear Factor I; NFIX; NFIA; NFIB; Spinal cord; Gliogenesis; GFAP; Astrocyte;
ATP released from astrocytes modulates action potential threshold and spontaneous excitatory postsynaptic currents in the neonatal rat prefrontal cortex
Keywords: آستروسیت; BzATP; 2â²(3â²)-O-(4-benzoylbenzoyl)adenosine-5â²-triphosphate tri(triethylammonium) salt; BBG; Brilliant blue G; PPADS; pyridoxalphosphate-6-azophenyl-2â²,4â²-disulfonic acid tetrasodium salt; LPS; lipopolysaccharide; MAM; methylazoxymethanol; PFC;
Parkinsonian features in aging GFAP.HMOX1 transgenic mice overexpressing human HO-1 in the astroglial compartment
Keywords: آستروسیت; α-Synuclein; Astrocyte; Dopamine; Heme oxygenase-1; Mitochondrial dysfunction; Oxidative stress; Parkinson disease;