Keywords: تنظیم کننده autoimmune; In vivo cell division; Thymus; EdU; Epithelial cell kinetics; Aire; Autoimmune regulator; BrdU; Bromodeoxyuridine; DP; double positive; EdU; 5-ethynyl-2â²-deoxyuridine; LN; lymph node; cTEC; cortical thymic epithelial cell; mTEC; medullary thymic epithel
مقالات ISI تنظیم کننده autoimmune (ترجمه نشده)
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Keywords: تنظیم کننده autoimmune; Gene therapy; Omenn syndrome; autoimmunity; lentiviral vector; Rag genes; AIRE; Autoimmune regulator; BAFF; B cell-activating factor; BM; Bone marrow; GT; Gene therapy; HSCT; Hematopoietic stem cell transplantation; Linâ; Lineage negative; LV; Lentivi
Keywords: تنظیم کننده autoimmune; AA; Alopecia Areata; AID; autoimmune disease; Aire; autoimmune regulator; APC; antigen-presenting cells; APS; autoimmune polyendocrine syndrome; CeD; celiac disease; CTLA; cytotoxic T-lymphocyte-associated protein; CXCL; chemokine (C-X-C motif) ligand; DC
Keywords: تنظیم کننده autoimmune; Autoimmunity; primary immunodeficiency diseases; BÂ cells; T cells; AID; Activation-induced cytidine deaminase; AIHA; Autoimmune hemolytic anemia; AIRE; Autoimmune regulator; ALPS; Autoimmune lymphoproliferative disease; ANA; Anti-nuclear autoantibody; AP
Keywords: تنظیم کننده autoimmune; ADA; adenosine deaminase; AIRE; autoimmune regulator; AML; acute myeloid leukemia; APECED; autoimmune polyendocrinopathy, candidiasis, and ectodermal dysplasia; APLAID; autoinflammation and PLCγ2-associated antibody deficiency and immune dysregulation; A
Keywords: تنظیم کننده autoimmune; AChR; acetylcholine receptor; AChR-Ab; acetylcholine receptor antibody; AIRE; autoimmune regulator; APECED; autoimmune polyendocriopathy candidiasis ectodermal dystrophy; APS-I; autoimmune polyendocrine syndrome type-I; EOMG; early onset Myasthenia gravis
Keywords: تنظیم کننده autoimmune; HGF; c-Met; Inflammation; Autoimmunity; Autoimmune regulator; Therapy;
Dominant-negative loss of function arises from a second, more frequent variant within the SAND domain of autoimmune regulator (AIRE)
Keywords: تنظیم کننده autoimmune; Autoimmune regulator; Type I diabetes mellitus; Next generation sequencing; Dominant-negative mutation; Immune tolerance;
The immunobiology and clinical features of type 1 autoimmune polyglandular syndrome (APS-1)
Keywords: تنظیم کننده autoimmune; APS-1; type 1 autoimmune polyglandular syndrome; AIRE; autoimmune regulator; mTECs; medullary thymic epithelial cells; CMC; chronic mucocutaneous candidiasis; T1D; type 1 diabetes; PGA I; polyglandular type I autoimmune syndrome; IFN; interferon; AIH; aut
Oestrogen, an evolutionary conserved regulator of T cell differentiation and immune tolerance in jawed vertebrates?
Keywords: تنظیم کننده autoimmune; Thymus; Spleen; Head-kidney; Teleost; Regulatory T cell; Gamma-delta T cell; AIRE; autoimmune regulator; APC; antigen-presenting cell; E2; 17β-oestradiol; EE2; 17α-ethinylestradiol; ETP; early thymic progenitor; FOXN1; forkhead-box n1; FOXP3; forkhead-b
Opinion paperRs3761389 polymorphism in autoimmune regulator (AIRE) gene is associated with susceptibility of myasthenia gravis in Chinese patients
Keywords: تنظیم کننده autoimmune; Myasthenia gravis; Autoimmune regulator; Polymorphism; Susceptibility; Severity;
Thymic epithelial cell-specific deletion of Jmjd6 reduces Aire protein expression and exacerbates disease development in a mouse model of autoimmune diabetes
Keywords: تنظیم کننده autoimmune; Jmjd6; Aire; Intron retention; Autoimmunity; TEC; thymic epithelial cell; MHC; major histocompatibility complex; mTEC; medullary TEC; Aire; autoimmune regulator; mOVA; membrane-bound form of ovalbumin; TCR; T cell receptor; UEA-1; Ulex europaeus agglutini
T cell receptor assessment in autoimmune disease requires access to the most adjacent immunologically active organ
Keywords: تنظیم کننده autoimmune; Next generation sequencing; T cell receptor repertoire; Autoimmune regulator;
The dual role of autoimmune regulator in maintaining normal expression level of tissue-restricted autoantigen in the thymus: A modeling investigation
Keywords: تنظیم کننده autoimmune; Thymic negative selection; Tissue-restricted antigens; Autoimmune regulator; Mathematical model; Bistable switch; T-cell avidity;
Thymus transplantation for complete DiGeorge syndrome: European experience
Keywords: تنظیم کننده autoimmune; DiGeorge syndrome; athymia; thymus transplantation; AIRE; Autoimmune regulator; ATG; Antithymocyte globulin; cDGS; Complete DiGeorge syndrome; CHARGE; Coloboma, heart defects, atresia choanae, retardation of growth and development, genital abnormalities,
B-1 B cell progenitors transiently and partially express keratin 5 during differentiation in bone marrow
Keywords: تنظیم کننده autoimmune; Aire; autoimmune regulator; CLP; common lymphoid precursor; dTg; double transgenic; EGFP; enhanced green fluorescent protein; K5; keratin 5; LPS; lipopolysaccharide; mDC; migratory dendritic cell; MLR; mixed lymphocyte reaction; mOVA; membrane-bound ovalb
AIRE genetic variants and predisposition to polygenic autoimmune disease: The case of Graves' disease and a systematic literature review
Keywords: تنظیم کننده autoimmune; AIRE; Autoimmune regulator; TRA; Tissue-restricted antigen; APECED; Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy; SNP; Single nucleotide polymorphism; TSHR; Thyroid stimulating hormone receptor; GWAS; Genome-wide association study; pGE;
Research PaperMyf5 and Myogenin in the development of thymic myoid cells - Implications for a murine in vivo model of myasthenia gravis
Keywords: تنظیم کننده autoimmune; AChR; Acetylcholine receptor; AIRE; Autoimmune regulator; EOMG; Early onset myasthenia gravis; LOMG; Late onset myasthenia gravis; LRP4; Low-density lipoprotein receptor-related protein 4; MG; Myasthenia gravis; MHC; Major histocompatibility complex; MuSK
Immune deficiencies, infection, and systemic immune disordersProtein microarrays identify disease-specific anti-cytokine autoantibody profiles in the landscape of immunodeficiency
Keywords: تنظیم کننده autoimmune; Anti-cytokine autoantibodies; immunodeficiency; autoimmune polyendocrine syndrome type I; pulmonary alveolar proteinosis; thymoma; protein microarray; ACAA; Anti-cytokine autoantibody; AIRE; Autoimmune regulator; APS-1; Autoimmune polyendocrine syndrome t
Association of rs2075876 polymorphism of AIRE gene with rheumatoid arthritis risk
Keywords: تنظیم کننده autoimmune; Autoimmune regulator; Rheumatoid arthritis; Single nucleotide polymorphism; C-reactive protein
A normal T cell receptor beta CDR3 length distribution in patients with APECED
Keywords: تنظیم کننده autoimmune; AIRE; autoimmune regulator; APECED; autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy; CDR3; complementarity determining region 3; TCR; T cell receptor; TSA; tissue-specific self-antigen; DP; CD4+ CD8+ double positive; SP; single positive
Dissecting the role of the foxp3 gene in the joint genetic susceptibility to autoimmune thyroiditis and diabetes: A genetic and functional analysis
Keywords: تنظیم کننده autoimmune; APS3v; autoimmune polyglandular syndrome type 3; AIRE; autoimmune regulator; AITD; autoimmune thyroiditis; bp; base pair(s); CTLA-4; cytotoxic T-lymphocyte antigen; Î; deletion; dNTP; deoxyribonucleoside triphosphate; FOXP3; Forkhead Box Protein 3; GAPDH
Disease specificity of anti-tryptophan hydroxylase-1 and anti-AIE-75 autoantibodies in APECED and IPEX syndrome
Keywords: تنظیم کننده autoimmune; AIE-75; autoimmune enteropathy-related 75Â kDa antigen; AIRE; autoimmune regulator; APECED; autoimmune polyendocrinopathy, candidiasis, ectodermal dystrophy; CMC; chronic mucocutaneous candidiasis; FOXP3; forkhead box transcription factor 3; GST; glutathi
Central T cell tolerance: Identification of tissue-restricted autoantigens in the thymus HLA-DR peptidome
Keywords: تنظیم کننده autoimmune; Peptides; Autoantigens; Tolerance; Thymus; Human; MHC; AIRE; autoimmune regulator; APECED; autoimmune polyendocrinopathy candidiasis ectodermal dystrophy; APC; antigen presenting cell; APS-1; autoimmune polyendocrine syndrome type 1; CT; cycle threshold;
Aire-dependent peripheral tissue antigen mRNAs in mTEC cells feature networking refractoriness to microRNA interaction
Keywords: تنظیم کننده autoimmune; Thymus; Aire gene; Peripheral tissue antigen; Post-transcriptional control; Self-tolerance; microRNAs; AID; autoimmune disease; Amelx; amelogenin X chromosome; Amy1; amylase 1, salivary; ANOVA; analysis of variance; Aire; autoimmune regulator; Alb; albumi
Embryonal Fyn-associated substrate (EFS) and CASS4: The lesser-known CAS protein family members
Keywords: تنظیم کننده autoimmune; 5-HT; 5-hydroxytryptamine, serotonin; A549; non-small cell lung cancer cell line; AD; Alzheimer's disease; ADPKD; autosomal dominant polycystic kidney disease; Aire; autoimmune regulator; AP-1; activator protein 1; APP; amyloid precursor protein; AREB6; Z
Diagnosis and classification of autoimmune parathyroid disease
Keywords: تنظیم کننده autoimmune; 21-OHAbs; 21-hydroxylase antibodies; AD; Addison's disease; ACA; adrenal cortex antibodies; AADC; aromatic l-amino acid decarboxylase autoantibodies; APS-1; autoimmune polyendocrine syndrome type 1; AIRE; AutoImmune REgulator; CaSR; calcium-sensing recept
Recombination-activating gene 1 (Rag1)-deficient mice with severe combined immunodeficiency treated with lentiviral gene therapy demonstrate autoimmune Omenn-like syndrome
Keywords: تنظیم کننده autoimmune; Severe combined immunodeficiency; lentiviral gene therapy; autoimmune reactions; AIRE; Autoimmune regulator; BAFF; B cell-activating factor; CMD; Corticomedullary differentiation; CP; Cell type-restricted promoter; DP; Double positive; dsDNA; Double-str
Thymic CCL2 influences induction of T-cell tolerance
Keywords: تنظیم کننده autoimmune; Tolerance; CCL2; Plasmacytoid dendritic cells; EAE; AIRE; autoimmune regulator; cDC; conventional DC; CNS; central nervous system; cTEC; cortical TEC; DN; double negative; DP; double positive; EAE; experimental autoimmune encephalomyelitis; MBP; myelin ba
Autoantibodies against aromatic amino acid hydroxylases in patients with autoimmune polyendocrine syndrome type 1 target multiple antigenic determinants and reveal regulatory regions crucial for enzymatic activity
Keywords: تنظیم کننده autoimmune; AAAH; aromatic amino acid hydroxylase; AI; autoantibody index; AIRE; autoimmune regulator; APECED; autoimmune polyendocrinopathy candidiasis ectodermal dystrophy; APS-1; autoimmune polyendocrine syndrome type 1; BH4; tetrahydropterin; BSA; bovine serum al
Breakdown of immune privilege and spontaneous autoimmunity in mice expressing a transgenic T cell receptor specific for a retinal autoantigen
Keywords: تنظیم کننده autoimmune; Autoimmune uveitis; Immune privilege; TCR transgenic mouse; Spontaneous disease; Ag; antigen; IRBP; interphotoreceptor retinoid binding protein; TCR; T cell receptor; CFA; complete Freund's adjuvant; EAU; experimental autoimmune uveitis; HEL; hen egg lyso
Analysis of the autoimmune regulator gene in patients with autoimmune non-APECED polyendocrinopathies
Keywords: تنظیم کننده autoimmune; ACA; adrenal cortex antibodies; ACTH; adrenocorticotropic hormone; AIH; autoimmune hepatitis; AIRE; autoimmune regulator; AMA; anti-mitochondrial antibodies; ANA; anti-nuclear antibodies; ANCA; anti-neutrophil cytoplasmic antibodies; APECED; autoimmune po
Screening for novel lead compounds increasing insulin expression in medullary thymic epithelial cells
Keywords: تنظیم کننده autoimmune; Type 1 diabetes; High-throughput screening assay; Medullary thymic epithelial cell; Insulin; Immune tolerance; Autoimmune regulator
TH17 deficiency in human disease
Keywords: تنظیم کننده autoimmune; TH cells; Candida species; fungi; TH17 cell; pathogen-recognition receptors; cytokines; transcription factors; differentiation; chronic mucocutaneous candidiasis; AD; Autosomal dominant; AIRE; Autoimmune regulator; APECED; Autoimmune polyendocrinopathy-
Thymic functions and gene expression profile distinct double-negative cells from single positive cells in the autoimmune lymphoproliferative syndrome
Keywords: تنظیم کننده autoimmune; ALPS; Autoimmune lympho-proliferative syndrome; DN; Double-negative; tDN; Thymic double-negative; PBMCs; peripheral blood mononuclear cells; SP; Single-positive; TCR; T-cell receptor; TRECs; T-cell receptor excision circles; Ct; Cycle threshold; qRT-PCR;
Autoimmune regulator (AIRE) contributes to Dectin-1-induced TNF-α production and complexes with caspase recruitment domain-containing protein 9 (CARD9), spleen tyrosine kinase (Syk), and Dectin-1
Keywords: تنظیم کننده autoimmune; Primary immunodeficiency; innate immunity; chronic mucocutaneous candidiasis; monocytes; AIRE; Autoimmune regulator; APECED; Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy; CARD9; Caspase recruitment domain-containing protein 9; CMC;
Overexpressing autoimmune regulator regulates the expression of toll-like receptors by interacting with their promoters in RAW264.7 cells
Keywords: تنظیم کننده autoimmune; Aire; autoimmune regulator; TLR; toll-like receptor; RAW264.7; mouse macrophage-like cell line; APECED; autoimmune polyendocrinopathy candidiasis ectodermal dystrophy; APS-1; autoimmune polyendocrine syndrome type I; mTEC; medullary thymic epithelial cell
ORAI-mediated calcium influx in T cell proliferation, apoptosis and tolerance
Keywords: تنظیم کننده autoimmune; AICD; activation induced cell death; AIRE; autoimmune regulator; APC; antigen-presenting cell; [Ca2+]i; intracellular Ca2+ concentration; CRAC channel; Ca2+ release-activated Ca2+ channel; CREB; cyclic-AMP-responsive element-binding protein; GALT; gut-ass
Cellular immunity and immunopathology in autoimmune Addison's disease
Keywords: تنظیم کننده autoimmune; 17OH; steroid cytochrome P450 17-alpha-hydroxylase; 21OH; steroid cytochrome P450 21-hydroxylase; AAD; autoimmune Addison's disease; ACA; adrenal cortex autoantibodies; ADCC; antibody dependent cellular cytotoxicity; AIRE; autoimmune regulator; APC; antig
Defect of regulatory T cells in patients with Omenn syndrome
Keywords: تنظیم کننده autoimmune; Immunodeficiency; V(D)J recombination; Omenn syndrome; regulatory T cells; FOXP3; anergy and tolerance; thymus and the development of T lymphocytes; AIRE; Autoimmune regulator; FOXP3; Forkhead box protein P3; HD; Healthy donor; OS; Omenn syndrome; RAG; Re
Impaired TH17 responses in patients with chronic mucocutaneous candidiasis with and without autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy
Keywords: تنظیم کننده autoimmune; Candida species, chronic mucocutaneous candidiasis, autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy, autoimmune polyendocrinopathy type 1, autoimmune regulator, primary immunodeficiency, TH17, IL-22; IFN-γ, cytokines; AIRE; Autoimmune
Advances in the Diagnosis, Pathogenesis, and Management of Autoimmune Hepatitis
Keywords: تنظیم کننده autoimmune; Phenotypic Diversity; Current and Future Therapies; Pathogenic Mechanisms; AIH; autoimmune hepatitis; AIRE; autoimmune regulator; ALT; alanine aminotransferase; ANA; antinuclear antibodies; anti-LC1; antibodies to liver cytosol type 1; anti-LKM; antibodie
Radioimmunoassay for autoantibodies against interferon omega; its use in the diagnosis of autoimmune polyendocrine syndrome type I
Keywords: تنظیم کننده autoimmune; Autoimmune polyendocrine syndrome I; Interferon omega; Radioimmunoassay; Autoimmune regulator
Modulation of Aire regulates the expression of tissue-restricted antigens
Keywords: تنظیم کننده autoimmune; Autoimmune regulator; Thymus; Tissue-restricted antigens; Autoimmunity;
Aire deficient mice do not develop the same profile of tissue-specific autoantibodies as APECED patients
Keywords: تنظیم کننده autoimmune; APS1; Autoantigen; Autoimmune regulator; Knock-out mouse