دانلود مقالات ISI درباره Bh3 + ترجمه فارسی

چگونه می توان محاصره آپوپتوتومی میتوکندری را برای کشتن سرطان آزاد کرد؟

How to unleash mitochondrial apoptotic blockades to kill cancers?

Keywords: ASH; American Society of Hematology; ATAP; amphipathic tail-anchoring peptide; BAD; BCL-2-associated death promoter protein; BAK; BCL-2 homologous antagonist killer; BAX; BCL-2-associated X protein; BCL-2; B-cell lymphoma 2; BCL-w (BCL2L2); BCL-2-like pro

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

استراتژی های درمانی نوین برای هدف قرار دادن سلول های لوسمی که نیش های سلولی سلول های بنیادی هماتوپوئیدی مدفوع را از بین می برند

Novel therapeutic strategies to target leukemic cells that hijack compartmentalized continuous hematopoietic stem cell niches

Keywords: AML; acute myeloid leukemia; ANG-1; angiopoietin-1; ALL; acute lymphoblastic leukemia; AKT; protein kinase B; Ara-C; cytarabine; AXL; tyrosine kinase receptor; BCL-2; B-cell lymphoma 2; BH3; BCL-2 homology 3; BMP; bone morphogenic protein; CAR cell; CXCL1

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

مکانیسم های مولکولی سمیت لیپتوکسین و سمیت گلوتاتیک در بیماری کبدی چربی غیرالکلی

Molecular mechanisms of lipotoxicity and glucotoxicity in nonalcoholic fatty liver disease

Keywords: NASH; CHOP; JNK; Lipid; Oxidative stress; ALA; alpha-linolenic; ACC; acetyl-CoA carboxylase; AMPK; AMP-activated protein kinase; ATF; activating transcription factor; AP-1; activator protein-1; BAs; bile acids; BH3; Bcl-2 homology 3; BIM; Bcl-2 interactin

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

اهمیت بالینی مهار کننده های گیرنده تیروسین کیناز گیرنده اپیدرمی: حساسیت و مقاومت

Clinical significance of epidermal growth factor receptor tyrosine kinase inhibitors: Sensitivity and resistance

Keywords: EGFR-TKI; epidermal growth factor receptor tyrosine kinase inhibitor; MST; median survival time; HGF; hepatocyte growth factor; FISH; fluorescence in situ hybridization; PTEN; phosphatase and tensin homolog deleted from chromosome 10; PI3K; phosphoinositi

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

درمان سرطان: هدف قرار دادن مسیر آپوپتوتیک

Cancer therapeutics: Targeting the apoptotic pathway

Keywords: Apoptosis; Cancer therapeutics; Extrinsic pathway; Intrinsic pathway; Bcl-2; BH3; IAPs

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2014 سفارش ترجمه

توالی ژنوم کامل و تجزیه و تحلیل سویه ویروس بیماری نیوکاسل ضد تومور

Complete genome sequencing and analysis of an anti-tumor Newcastle disease virus strain

Keywords: aa; amino acid(s); APMV-1; avian paramyxovirus-1; BH3; Bcl-2 homology domain 3; BGI; Beijing Genomics Institute; BSL-2; biosafety level 2; cDNA; DNA complementary to RNA; F; fusion protein; F; phenylalanine; G; guanine; GE; gene end; GS; gene start; HA; h

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Re-evaluating the role of FOXOs in cancer

Keywords: RTK; receptor tyrosine kinase; GF; growth factor; PI3K; Phosphatidylinositol-4,5-bisphosphate 3-kinase; PKB; protein kinase B; AKT; RAC-alpha serine/threonine-protein kinase; FOXO; forkhead box O; GFR; growth factor receptor; PDPK1; Phosphoinositide-depen

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Influence of silibinin and β-β-dimethylacrylshikonin on chordoma cells

Keywords: Chordoma; β-β-dimethylacrylshikonin; Silibinin; Apoptosis; ACTB; actin beta; AKT; AKT serine/threonine kinase; BAD; BCL2 associated agonist of cell death; BAK; BCL2 antagonist/killer; BAX; BCL2 associated X protein; BCL-2; B cell leukemia/lymphoma 2; BH

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2018 سفارش ترجمه

The pro-apoptotic protein Bmf co-operates with Bim and Puma in neuron death induced by β-amyloid or NGF deprivation

Keywords: Bmf; Bcl2 Modifying Factor; PUMA; p53 upregulated modulator of apoptosis; PC12; Pheochromocytoma cells; Bcl-2; B-cell lymphoma 2; BH3; Bcl-2 homology domain 3; Bim; Bcl-2 interacting mediator of cell death; Mcl-1; Myeloid cell leukemia 1; Bak; Bcl-2 antag

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2018 سفارش ترجمه

Distinct apoptotic blocks mediate resistance to panHER inhibitors in HER2+ breast cancer cells

Keywords: Δψm; mitochondrial membrane potential; FCCP; carbonylcyanide-4-(trifluoromethoxy)-phenylhydrazone; FITC; fluorescein isothiocyanate; BSA; bovine serum albumin; JC-1; 5,5′,6,6′-tetrachloro-1,1′,3,3′-tetraethylbenzimidazolylcarbocyanine iodide; MO

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2018 سفارش ترجمه

Autophagy in hemorrhagic stroke: Mechanisms and clinical implications

Keywords: AIM2; absent in melanoma 2; AMPK; Adenosine 5′ monophosphate-activated protein kinase; ASC; apoptosis-associated speck-like protein containing a CARD; BBB; blood-brain barrier; BH3; Bcl-2 homology 3; BMVECs; brain microvascular endothelial cells; BNIP3;

دانلود رایگان متن کامل مقاله ISI 104 صفحه سال انتشار : 2018 سفارش ترجمه

Original ArticleMetabolic reprogramming and apoptosis sensitivity: Defining the contours of a T cell response

Keywords: Immunometabolism; Apoptosis; T cells; Restimulation-induced cell death; Cytokine withdrawal-induced cell death; CWID; AICD; Activation-induced cell death; Bcl-2; B cell lymphoma 2; BH3; Bcl-2 domain homology 3; CM; Central memory; COX; Cytochrome c oxidas

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Expression, purification and characterization of hepatitis B virus X protein BH3-like motif-linker-Bcl-xL fusion protein for structural studies

Keywords: Bcl-2; B-cell lymphoma 2; Bcl-xL; B-cell lymphoma extra large; BH3; Bcl-2 homology 3; HBV; hepatitis B virus; HBx; hepatitis B virus X protein; HCC; hepatocellular carcinoma; HSQC; heteronuclear single quantum coherence; BH3-like motif; Bcl-xL; Fusion pro

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Crosstalk control and limits of physiological c-Jun N-terminal kinase activity for cell viability and neurite stability in differentiated PC12 cells

Keywords: Akt; protein kinase B; ATF; activating transcription factor; ATP; adenosine triphosphate; BH3; Bcl-2 homology domain 3; cIAP1; cellular inhibitor of apoptosis 1; CREB; cAMP response element-binding protein; ECL; enhanced chemiluminescence; EDTA; ethylened

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Inhibition of histone/lysine acetyltransferase activity kills CoCl2-treated and hypoxia-exposed gastric cancer cells and reduces their invasiveness

Keywords: Ac; acetylated; BH3; Bcl2 homology 3; CM-H2-DCFDA; 5-(and 6)-chloromethyl-2,7-dichlorodihydrofluorescein diacetate acetyl ester; CoCl2·6H2O; cobalt chloride hexahydrate; Cyt c; cytochrome c; DAPI; (4′,6-Diamidino-2-phenylindole Dilactate; ERK; extracel

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Identification of 3,4-dihydro-2H-thiochromene 1,1-dioxide derivatives with a phenoxyethylamine group as highly potent and selective α1D adrenoceptor antagonists

Keywords: Phenoxyethylamine derivatives; Selective human α1D adrenoceptor antagonist; 3,4-Dihydro-2H-thiochromene 1,1-dioxide; Ligand-lipophilicity efficiency (LLE); AR; Adrenoceptor; BH3; borane; Boc2O; di-tert-butyl bicarbonate; t-BuXphos; 2-di-tert-butylphosp

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2017 سفارش ترجمه

Down-regulation of BNIP3 by olomoucine, a CDK inhibitor, reduces LPS- and NO-induced cell death in BV2 microglial cells

Keywords: Aβ; amyloid β; BH3; Bcl−2 homology domain 3; BNIP3; Bcl-2/adenovirus E1B 19−kDa-interacting protein 3; CNS; central nervous system; cPTIO; carboxy-PTIO; CDK; cyclin-dependent kinase; DMEM; Dulbecco's modified Eagle medium; HD; Huntington's disea

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Astemizole-Histamine induces Beclin-1-independent autophagy by targeting p53-dependent crosstalk between autophagy and apoptosis

Keywords: AST; Astemizole; HIS; Histamine; H1R; Histamine H1 receptor; ROS; Reactive oxygen species; ER; Endoplasmic reticulum; PERK; Protein kinase R-like endoplasmic reticulum kinase; IRE1α; Inositol-requiring enzyme 1; ATF; Activating transcription factor; JNK;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Mitochondria: An intriguing target for killing tumour-initiating cells

Keywords: AML; acute myeloid leukaemia; BH3; Bcl-2 homology-3; CII; complex II; CSCs; cancer stem cells; MitoVES; mitochondrially targeted vitamin E succinate; ROS; reactive oxygen species; SCs; stem cells; TICs; tumour-initiating cells; α-TOS; α-tocopheryl succi

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2016 سفارش ترجمه

Small molecule Mcl-1 inhibitors for the treatment of cancer

Keywords: Mcl-1; Myeloid cell leukemia-1; Inhibitors; Small molecule; BH3-mimetic; Bad; Bcl-2-associated death promoter; Bak; Bcl-2 homologous antagonist/killer; Bax; Bcl-2 associated X; Bcl-2; B-cell lymphoma-2; BH; Bcl-2 homology; BH3; Bcl-2 homology domain 3; Bc

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

BCL-2 family protein, BAD is down-regulated in breast cancer and inhibits cell invasion

Keywords: AIF; apoptosis inducible factor; AP-1; activator protein-1; AKT; protein kinase B; Apaf-1; apoptosis protease activating factor-1; BAD; Bcl-2-associated death promoter; BCL-2; B-cell lymphoma 2; BCLxL; B-cell lymphoma-extra large; BH3; Bcl-2 homology doma

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

The roles of DNA damage-dependent signals and MAPK cascades in tributyltin-induced germline apoptosis in Caenorhabditis elegans

Keywords: ANOVA; analysis of variance; AO; acridine orange; Apaf-1; apoptotic protease-activating factor-1; ASK; apoptosis signal-regulating kinase; BH3; Bcl-2 homology region 3; DAPI; 4′,6-diamidino-2-phenylindole; DDR; DNA damage response; DMSO; dimethyl sulfox

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

BH3-mimetic drugs prevent tumour onset in an orthotopic mouse model of hepatoblastoma

Keywords: HB; hepatoblastoma; SR; standard risk; HR; high risk; MDR; multi drug resistance; CDDP; cisplatin; BH3; Bcl-2 homology domain; High-risk hepatoblastoma; BH3-mimetic drugs; Tumour cell migration; Orthotopic HB model; TRAIL; TNF-α; ABT-737; Obatoclax; Paed

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Role of Bcl-xL/Beclin-1 in interplay between apoptosis and autophagy in oxaliplatin and bortezomib-induced cell death

Keywords: JNK; c-Jun NH2-terminal kinase; Bcl-xL; B-cell lymphoma-extra large; BAX; Bcl-2-associated X protein; PARP; Poly (ADP-ribose) polymerase; COX; Cyclooxygenase; SDS; Sodium dodecyl sulfate; PAGE; Polyacrylamide gel electrophoresis; BH3; Bcl-2 homology domai

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

MicroRNAs as regulators of mitochondrial function: Role in cancer suppression

Keywords: ACL; ATP citrate lyase; AGO; Argonaut; ARL2; ADP-ribosylation factor-like 2; BH3; Bcl-2 homology-3; CAT; catalase; COX IV; cytochrome c oxidase IV; CI; complex I; CII; complex II; CIV; complex IV; CPT; camptothecin; DGCR8; DiGeorge syndrome critical regio

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

NF-κB activation fails to protect cells to TNFα-induced apoptosis in the absence of Bcl-xL, but not Mcl-1, Bcl-2 or Bcl-w

Keywords: Bcl-2; B-cell lymphoma 2; Bcl-xL; B-cell lymphoma-extra large; Bcl-w; Bcl-2-like protein 2; BH3; Bcl-2 homology 3; cIAP-2; cellular inhibitor of apoptosis protein 2; DMEM; Dulbecco' s modified eagle medium; ERK; extracellular signal-regulated kinase; FBS;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Regulation of inositol 1,4,5-trisphosphate receptors during endoplasmic reticulum stress

Keywords: a.a.; amino acid; ATF; activating transcription factor; Bcl-2; B-cell lymphoma 2; Bcl-Xl; B-cell lymphoma-extra large; BH3; Bcl-2 homology 3; BI-1; Bax inhibitor-1; BiP; immunoglobulin heavy chain-binding protein; CHOP; C/EBP-homologous protein; CSQ; cals

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Cellular metabolic and autophagic pathways: Traffic control by redox signaling

Keywords: Ambra; activating molecule in beclin 1-regulated autophagy; AMPK; AMP kinase; Atg; autophagy-related gene; Bcl-2; B-cell lymphoma 2; BH3; Bcl-2 homology domain 3; BNIP; Bcl-2/adenovirus E18 19-kDa-interacting protein; CMA; chaperone-mediated autophagy; eN

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2013 سفارش ترجمه

BH3 profiling – Measuring integrated function of the mitochondrial apoptotic pathway to predict cell fate decisions

Keywords: Apoptosis; Mitochondria; BH3-only; BH3; BCL-2

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

Evolution of Bcl-2 homology motifs: homology versus homoplasy

Keywords: Bcl-2 family; BH3; sequence motifs; protein homology; apoptosis; evolution

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Evading apoptosis in cancer

Keywords: BH3; caspase; MOMP; phosphorylation; ubiquitination

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

Theoretical investigation on the interactions between borazine and first-row hydrides

Keywords: Borazine; SAPT; BH3; Electrostatic;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Mitochondrial Ca2+ signals in autophagy

Keywords: mTOR; mammalian target of rapamycin; InsP3R; inositol 1,4,5-trisphosphate receptor; AMPK; adenosine monophosphate activated protein kinase; mTORC1; mammalian target of rapamycin complex 1; GAP; GTPase activating protein; TSC1/TSC2; tuberous sclerosis comp

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Associate editor: M. PanagiotidisStress management at the ER: Regulators of ER stress-induced apoptosis

Keywords: ASK1; apoptosis signal-regulating kinase 1; ATF; activating transcription factor; BAK; Bcl-2 homologous antagonist/killer; BAX; Bcl-2 associated protein X; BCL-2; B-cell lymphoma 2; BH3; Bcl-2 homology domain 3; BI-1; Bax inhibitor 1; Bim; Bcl-2 interacti

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Mitochondrial outer membrane permeabilization during apoptosis: The role of mitochondrial fission

Keywords: MOMP; mitochondrial outer membrane permeabilization; MIM; mitochondrial inner membrane; MOM; mitochondrial outer membrane; IMS; intermembrane space; BH3; Bcl-2 homology domain 3; MEFs; mouse embryonic fibroblasts; Mitochondria; Apoptosis; Fission; Fusion;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Mitochondrial targeting of α-tocopheryl succinate enhances its pro-apoptotic efficacy: A new paradigm for effective cancer therapy

Keywords: BH3; Bcl-2 homology domain 3; CII; complex II; ChIP; chromatin immunoprecipitation; DHE; dihydroethidium; DMPO; 5,5-dimethyl-1-pyrroline N-oxide; EPR; electron paramagnetic resonance; MIM; mitochondrial inner membrane; MitoQ; mitochondrially targeted coen

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Bim is reversibly phosphorylated but plays a limited role in paclitaxel cytotoxicity of breast cancer cell lines

Keywords: Paclitaxel; Taxanes; Apoptosis; BH3; Bim

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Apoptosis induction by Bcl-2 proteins independent of the BH3 domain

Keywords: Apoptosis; Bcl-2 proteins; BH3; BH4; Bcl-x

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

S100A8/9 induces cell death via a novel, RAGE-independent pathway that involves selective release of Smac/DIABLO and Omi/HtrA2

Keywords: ΔΨm; mitochondrial membrane potential; AIF; apoptosis-inducing factor; BH3; Bcl2 homology 3; BNIP3; Bcl2/adenovirus E1B 19 kD-interacting protein 3; DD; death domain; DED; death effector domain; DISC; death inducing signaling complex; Drp; dynamin-rela

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2008 سفارش ترجمه

The nerve growth factor and its receptors in airway inflammatory diseases

Keywords: ADAM; a disintegrin and metalloprotease domain; AP-1; activating protein 1; AP-2; clathrin adaptative protein-2; APPL; amyloid precursor protein-like; ARMS; ankyrin repeat-rich membrane spanning; BDNF; brain-derived neurotrophic factor; bFGF; basic fibrob

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2008 سفارش ترجمه

Robust lanthanide-based assays for the detection of anti-apoptotic Bcl-2-family protein antagonists

Keywords: Bcl-2; FRET; Bcl-xL; Apoptosis; BH3

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

The HBSP gene is expressed during HBV replication, and its coded BH3-containing spliced viral protein induces apoptosis in HepG2 cells

Keywords: HBV replication; Apoptosis; HBSP; BH3;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Human hepatitis B virus X protein induces apoptosis in HepG2 cells: Role of BH3 domain

Keywords: HBX; BH3; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

Dying a Thousand Deaths: Redundant Pathways From Different Organelles to Apoptosis and Necrosis

Keywords: Akt; proto-oncogene product of the viral oncogene v-akt; AIF; apoptosis inducing factor; Apaf-1; apoptotic protease activating factor-1; ATF6; activating transcription factor 6; Bad; heterodimeric partner for Bcl-xL and Bcl-2; Bak; Bcl2 homologous antagon

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه