دانلود مقالات ISI درباره وابستگی + ترجمه فارسی

Design, synthesis and biological evaluation of nonsecosteroidal vitamin D3 receptor ligands as anti-tumor agents

Keywords: وابستگی; Vitamin D3; VDR ligand; Nonsecosteroidal; Phenyl-pyrrolyl pentane skeleton; Binding affinity; Agonistic activity; Anti-proliferative activity;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

Alu insertion/deletion of ACE gene polymorphism might not affect significantly the serum bradykinin level in hypertensive patients taking ACE inhibitors

Keywords: وابستگی; Binding affinity; Angiotensin; Bradykinin; I/D variant ACE; ACE inhibitor;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Virtual screening and biophysical studies lead to HSP90 inhibitors

Keywords: وابستگی; 17-AAG; 17-allylamino-17-demethoxygeldanamycin; 17-DMAG; 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin (17-DMAG); ADP; adenosine diphosphate; AMPPCP; 5′-adenylylmethylenediphosphonate; ASP; Astex statistical potential; ATP; adenosine triphosphat

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Synthèse et affinité de fixation aux récepteurs d'hormones stéroïdes humains de 3-phénoxy-4-hydroxycoumarines et de 3-phénoxy-4-phénylcoumarines

Keywords: وابستگی; Phénoxycoumarines; Récepteurs d'hormones stéroïdes; Affinité de fixation; Phenoxycoumarins; Steroid hormone receptors; Binding affinity;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Binding mode analyses of NAP derivatives as mu opioid receptor selective ligands through docking studies and molecular dynamics simulation

Keywords: وابستگی; NAP derivatives; Opioid receptors; Molecular modeling; Dual binding modes; Binding affinity; Selectivity;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

111In-DTPA-d-Phe− 1-Asp0-d-Phe1-octreotide exhibits higher tumor accumulation and lower renal radioactivity than 111In-DTPA-d-Phe1-octreotide

Keywords: وابستگی; 111In-DTPA-conjugated octreotide derivatives; Tumor accumulation; Somatostatin receptor; Binding affinity; Endocytosis;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Discovery of novel inhibitors of anti-apoptotic Bcl-2 proteins derived from Bim BH3 domain

Keywords: وابستگی; Apoptosis; Anti-apoptotic Bcl-2 proteins; Bim BH3 domain; Binding affinity; Anti-cancer activity;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Research ArticleIn silico 3-D structure prediction and molecular docking studies of inosine monophosphate dehydrogenase from Plasmodium falciparum

Keywords: وابستگی; Growing resistance; P. falciparum; Homology modeling; X-ray crystal structure; In-silico; Ribavirin derivatives; Binding affinity; Synthetic medicinal chemist;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis and biological evaluation of (R)-3,3,3-trifluoro-2-hydroxy-2-methylpropionamides as pyruvate dehydrogenase kinase 1 (PDK1) inhibitors to reduce the growth of cancer cells

Keywords: وابستگی; Pyruvate dehydrogenase kinase; Pyruvate dehydrogenase complex; Anti-proliferation; Binding affinity;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2017 سفارش ترجمه

Development of efficient docking strategies and structure-activity relationship study of the c-Met type II inhibitors

Keywords: وابستگی; c-Met; Docking; Binding affinity; Conformation; Force field; Computational screening;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2017 سفارش ترجمه

New insights on the role of alkaline phosphatase 2 from Spodoptera exigua (Hübner) in the action mechanism of Bt toxin Cry2Aa

Keywords: وابستگی; Spodoptera exigua; ALP2; Insecticidal efficiency; Binding affinity;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2017 سفارش ترجمه

Spider acetylcholine binding proteins: An alternative model to study the interaction between insect nAChRs and neonicotinoids

Keywords: وابستگی; Acetylcholine binding proteins; Pardosa pseudoannulata; Neonicotinoid; Binding affinity;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

A docking model of dapsone bound to HLA-B*13:01 explains the risk of dapsone hypersensitivity syndrome

Keywords: وابستگی; Dapsone; 4,4′-diaminodiphenylsulfone; DHS; dapsone hypersensitivity syndrome; HLA; human leukocyte antigen; 3D; three-dimensional; MD; molecular dynamics; MM-PBSA; molecular mechanics Poisson-Boltzman surface area; TEN; toxic epidermal necrolysis; SJS;

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2017 سفارش ترجمه

Relocation of a biological photosensitizer from non-ionic micellar carrier to DNA: A multispectroscopic investigation

Keywords: وابستگی; Phenosafranin; Micelle; DNA; Binding affinity; Intercalation; Relocation;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Differential scanning fluorimetry based assessments of the thermal and kinetic stability of peptide-MHC complexes

Keywords: وابستگی; DSF; differential scanning fluorimetry; Tm; melting temperature; CD; circular dichroism; MHC protein; Binding affinity; Thermal stability; Kinetic stability; Differential scanning fluorimetry;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Binding activities of non-β-glucan glycoclusters to dectin-1 and exploration of their binding site

Keywords: وابستگی; Dectin-1; Non-β-glucan glycocluster; Binding affinity; Binding site;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

IBI302, a promising candidate for AMD treatment, targeting both the VEGF and complement system with high binding affinity in vitro and effective targeting of the ocular tissue in healthy rhesus monkeys

Keywords: وابستگی; VEGF; Complement proteins; Bispecific; Binding affinity; Pharmacokinetics; ACP; alternative complement pathway; AMD; age-related macular degeneration; AUC; areas under the curve; CCK-8; Cell Counting Kit-8; CCP; classical complement pathway; CL; clearance

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Synthesis and evaluation of 2,5 and 2,6 pyridine-based CXCR4 inhibitors

Keywords: وابستگی; Pyridine; CXCR4 inhibitor; Matrigel invasion; Binding affinity; Cancer metastasis; Anti-inflammatory;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Symmetrical bis-tertiary amines as novel CXCR4 inhibitors

Keywords: وابستگی; Tertiary amines; CXCR4 inhibitors; Binding affinity; Matrigel invasion; Anti-inflammatory activity;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Biophysical and in vitro absorption studies of iron chelating peptide from barley proteins

Keywords: وابستگی; Barley protein peptide; Iron-chelating peptide; Binding affinity; Complexation model; Iron uptake; Ferritin;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Translocator protein ligands based on N-methyl-(quinolin-4-yl)oxypropanamides with properties suitable for PET radioligand development

Keywords: وابستگی; Translocator protein; PET; Carbon-11; Ligand; Binding affinity; Lipophilic efficiency; DIPEA; diisopropylethylamine; DMF; N,N-dimethylformamide; DMSO; dimethylsulfoxide; HFIP; hexafluoroisopropyl alcohol; HRMS-ESI; high resolution mass spectrometry electr

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Biomolecule–nanoparticle interactions: Elucidation of the thermodynamics by isothermal titration calorimetry

Keywords: وابستگی; Nanoparticles; Protein corona; Heat exchange; Binding affinity; Isothermal titration calorimetry

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Structure-based design and evaluation of novel N-phenyl-1H-indol-2-amine derivatives for fat mass and obesity-associated (FTO) protein inhibition

Keywords: وابستگی; FTO protein inhibitors; Anti-obesity; Molecular docking; Binding affinity; Molecular dynamics simulation;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Modification of the anabaseine pyridine nucleus allows achieving binding and functional selectivity for the α3β4 nicotinic acetylcholine receptor subtype

Keywords: وابستگی; Neuronal nicotinic acetylcholine receptors; Molecular modeling; Design; Anabaseine-related derivatives; α3β4 nicotinic ligands; Binding affinity; Functional activity/selectivity;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Marine derived compounds as binders of the White spot syndrome virus VP28 envelope protein: In silico insights from molecular dynamics and binding free energy calculations

Keywords: وابستگی; White spot syndrome virus; VP28; Envelope protein; Docking; Virtual screening; Dynamics; Binding affinity;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2016 سفارش ترجمه

Identification of acylthiourea derivatives as potent Plk1 PBD inhibitors

Keywords: وابستگی; Polo-like kinase 1; Polo-box domain; Small molecular inhibitor; Halogenosulfamoylphenyl acylthiourea; Binding affinity; In vitro assay;

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2016 سفارش ترجمه

Computer-assisted design, synthesis, binding and cytotoxicity assessments of new 1-(4-(aryl(methyl)amino)butyl)-heterocyclic sigma 1 ligands

Keywords: وابستگی; Sigma receptors; Binding affinity; Cytotoxicity; Molecular modeling;

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2016 سفارش ترجمه

Synthesis and biological activities of vitamin D3 derivatives with cyanoalkyl side chain at C-2 position

Keywords: وابستگی; Vitamin D3; 2α-Functionalized vitamin D; Vitamin D receptor; Binding affinity; Transactivation; X-ray co-crystallographic analysis;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2015 سفارش ترجمه

Five eIF4E isoforms from Arabidopsis thaliana are characterized by distinct features of cap analogs binding

Keywords: وابستگی; eIF4E; Cap analog; Binding affinity; Fluorescence titration; Homology modeling;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

In silico prediction of ebolavirus RNA polymerase inhibition by specific combinations of approved nucleotide analogues

Keywords: وابستگی; Ebolavirus; Polymerase; Nucleotide analogues; Modeling; Binding affinity;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Co-operative binding assay for the characterization of mGlu4 allosteric modulators

Keywords: وابستگی; Metabotropic glutamate receptor; Parkinson disease; mGlu4; Binding affinity;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Role of electrolyte in the occurrence of the voltage induced phase transitions in a dioleoyl phosphatidylcholine monolayer on Hg

Keywords: وابستگی; DOPC; phase transitions; binding affinity; electrolyte ions; electric fields

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

The cis conformation of proline leads to weaker binding of a p53 peptide to MDM2 compared to trans

Keywords: وابستگی; Intrinsically disordered protein; cis–trans isomerization; Binding affinity; Molecular dynamics; Potential of mean force

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Affinities of organophosphate flame retardants to tumor suppressor gene p53: An integrated in vitro and in silico study

Keywords: وابستگی; OPFRs; organophosphate flame retardants; TCEP; Tris(2-chloroethyl)phosphate; TCPP; Tris(2-chloroisopropyl)phosphate; TPrP; Tris(2-chloroisopropyl)phosphate; DnBP; di-n-butylphosphate; TEHP; Tris(2-ethylhexyl)phosphate; TPhP; triphenylphosphate; TEP; triet

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Homology modelling and molecular docking of MDR1 with chemotherapeutic agents in non-small cell lung cancer

Keywords: وابستگی; MDR1; Homology modelling; Binding affinity; Chemotherapeutics; Non-small cell lung cancer

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

A comparative study of binding affinities for 6,7-dimethoxy-4-pyrrolidylquinazolines as phosphodiesterase 10A inhibitors using the linear interaction energy method

Keywords: وابستگی; Phosphodiesterase 10A; Schizophrenia; Pyrrolidylquinazoline; Binding affinity; Linear interaction energy; Virtual screening and applicability domain

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Molecular docking of chemotherapeutic agents to CYP3A4 in non-small cell lung cancer

Keywords: وابستگی; CYP3A4; Binding affinity; Drug metabolism; Chemotherapeutics; Non-small cell lung cancer

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Identification of tyrosinase specific inhibitors from Xanthium strumarium fruit extract using ultrafiltration-high performance liquid chromatography

Keywords: وابستگی; Ultrafiltration; HPLC; Tyrosinase inhibitor; Binding affinity; Xanthium strumarium

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Glycation of the high affinity NGF-receptor and RAGE leads to reduced ligand affinity

Keywords: وابستگی; Advanced glycation endproducts (AGEs); Glycation; RAGE; Binding affinity; Neuronal plasticity; TrkA

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting

Keywords: وابستگی; Oncogenic microRNA; RNA recognition; Inhibitors; Binding affinity; Antibiotics;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Mono- and binuclear copper(II) complexes of the bipyridine ligand: Structural, electrochemical and biological studies

Keywords: وابستگی; Bipyridine; Hirshfeld surface; Binding affinity; Cleavage studies; Antimicrobial activity

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

The formation mechanism of secondary phases in Cu2ZnSnSe4 absorber layer

Keywords: وابستگی; Secondary phase; Binding affinity; CZTSe; Stacking order; Sequence; Layer; Formation;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

Bifunctional compounds targeting both D2 and non-α7 nACh receptors: Design, synthesis and pharmacological characterization

Keywords: وابستگی; Neuronal nicotinic acetylcholine receptors; α4β2 nAChRs; D2 receptors; Bifunctional ligands; Binding affinity; Electrophysiological assays; Erk phosphorylation tests; Dopamine release; Nicotine addiction;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2015 سفارش ترجمه

Synthesis of mouse centromere-targeted polyamides and physico-chemical studies of their interaction with the target double-stranded DNA

Keywords: وابستگی; DNA recognition; Minor-groove binders; Fluorescent probes; Pyrrole-imidazole polyamides; Binding affinity; Polyamide tandem;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2015 سفارش ترجمه

HQSAR and topomer CoMFA for predicting melanocortin-4 receptor binding affinities of trans-4-(4-chlorophenyl) pyrrolidine-3-carboxamides

Keywords: وابستگی; Melanocortin-4 receptor; Binding affinity; Hologram QSAR; Topomer CoMFA; Docking; Piperazinecyclohexanes;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2015 سفارش ترجمه

Effects of pH and protein conformation on in-solution complexation between bovine α-lactalbumin and oleic acid: Binding trend analysis by using SPR and ITC

Keywords: وابستگی; Protein-fatty acid complex; α-Lactalbumin; Oleic acid; Binding affinity; HAMLET; SPR; ITC; Molecular interactions;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2015 سفارش ترجمه

Complexes of green tea polyphenol, epigalocatechin-3-gallate, and 2S albumins of peanut

Keywords: وابستگی; 2S albumins; Binding affinity; Epigallocatechin-3-gallate; Fluorophore quenching; Molecular docking; Peanut; Polyphenol;

دانلود رایگان متن کامل مقاله ISI 63 صفحه سال انتشار : 2015 سفارش ترجمه

Synthesis and binding profile of haloperidol-based bivalent ligands targeting dopamine D2-like receptors

Keywords: وابستگی; Bivalent ligands; Dopamine; Binding affinity; GPCR dimers; D2 receptor; D3 receptor; D4 receptor;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Vasonatrin peptide stimulates both of the natriuretic peptide receptors, NPRA and NPRB

Keywords: وابستگی; Vasonatrin peptide; Natriuretic peptide; Natriuretic peptide receptor; Molecular dynamics; Binding affinity;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

The interaction between organic phosphate ester and p53: An integrated experimental and in silico approach

Keywords: وابستگی; Organophosphate flame retardants (OPFRs); p53; Docking; Quantitative structure-activity relationship (QSAR); Binding affinity; Multiple linear regression (MLR);

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه