دانلود مقالات ISI درباره وابستگی + ترجمه فارسی

Comparisons of the influenza virus A M2 channel binding affinities, anti-influenza virus potencies and NMDA antagonistic activities of 2-alkyl-2-aminoadamantanes and analogues

Keywords: وابستگی; Amantadine; Aminoadamantane derivatives; M2 ion channel; Influenza A; Binding affinity; Antiviral activity; NMDA antagonistic activity

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

In vitro pharmacodynamics of moxifloxacin versus levofloxacin against 4 strains of Streptococcus pneumoniae: 1 wild type, 2 first-step parC mutants, and 1 pump mutant

Keywords: وابستگی; Binding affinity; DNA gyrase; Topoisomerase IV

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Syntheses of tetrahydrothiophenes and tetrahydrofurans and studies of their derivatives as melanocortin-4 receptor ligands

Keywords: وابستگی; Synthesis; Tetrahydrothiophene; Tetrahydrofuran; Melanocortin-4 receptor; Cyclization; Heterocycle; Piperazinebenzylamine; Stereoisomer; Binding affinity

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

In vitro and in vivo profiling of fadolmidine, a novel potent α2-adrenoceptor agonist with local mode of action

Keywords: وابستگی; α2-Adrenoceptor; Agonist; Analgesia; Binding affinity; Cardiovascular; Fadolmidine; Mydriasis; Spontaneous motility

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Affinity of IgE and IgG against cross-reactive carbohydrate determinants on plant and insect glycoproteins

Keywords: وابستگی; CCDs; carbohydrate determinant; binding affinity; glycoprotein; CCD; Cross-reactive carbohydrate determinant; GlcNAc; N-acetylglucosamine∗; HRP; Horseradish peroxidase; MM; Manα1-6(Manα1-3)Manβ1-4GlcNAcβ1-4GlcNAc; MMF3 (MMF); Manα1-6(Manα1-3)Manβ

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

IGF-I binding to the IGF-I receptor is affected by contaminants in commercial BSA: The contaminants are proteins with IGF-I binding properties

Keywords: وابستگی; IGF; Receptor; Binding affinity; Insulin; Albumin; BSA; Hybrid receptor binding

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Molecular aspects on the interaction of phenosafranine to deoxyribonucleic acid: Model for intercalative drug–DNA binding

Keywords: وابستگی; Phenosafranine; DNA; Interaction; Binding mode; Binding affinity; Intercalation model; Spectroscopy; Thermodynamics; Drug–DNA interaction

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Cyclic analogs of α-melanocyte-stimulating hormone (αMSH) with high agonist potency and selectivity at human melanocortin receptor 1b

Keywords: وابستگی; Aic; 2-amino-indane-2-carboxylic acid; Bip(4,4′); 4,4′-biphenylalanine; Cha; cyclohexylalanine; Chg; cyclohexylglycine; Nal(2′); 2′-naphthylalanine; Phg; phenylglycine; Pip; pipecolic acid; Tic; tetrahydroquinoline-3-carboxylic acid; Melanocortin;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Substrate proton to heme distances in CYP2C9 allelic variants and alterations by the heterotropic activator, dapsone

Keywords: وابستگی; Cytochrome P450; CYP2C9; Kinetics; Activation; Proton distance; T1 NMR; Genetic polymorphism; Variant; Binding affinity;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Receptor interactions by polybrominated diphenyl ethers versus polychlorinated biphenyls: A theoretical structure–activity assessment

Keywords: وابستگی; Polybrominated diphenyl ethers; PBDEs; Polychlorinated biphenyls; PCBs; AhR; CAR; PXR; ER; AR; PR; DHT; TH; T3; T4; IGF; PPAR; RyR; GR; GABA; Conformation; Constitution; Binding affinity; Polarizability; Hydrophilicity; Gibbs free solvation energy; Induct

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

The role of lipophilicity in determining binding affinity and functional activity for 5-HT2A receptor ligands

Keywords: وابستگی; Lipophilicity; Binding affinity; Functional activity; 5-HT2A receptor

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Analysis of binding residues between scorpion neurotoxins and D2 dopamine receptor: A computational docking study

Keywords: وابستگی; D2 dopamine receptor; Scorpion neurotoxins; Molecular docking; Binding affinity; Molecular modeling; Stabilization centers; Stabilizing residues

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

Synthesis and structure–activity relationships of a series of benzazepine derivatives as 5-HT2C receptor agonists

Keywords: وابستگی; 5-HT2C receptor agonist; Binding affinity; Benzazepine; YM348

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

3- and 19-Oximes of 16α,17α-cyclohexanoprogesterone derivatives: Synthesis and interactions with progesterone receptor and other proteins

Keywords: وابستگی; Oxime derivatives; NMR spectroscopy; Progesterone; Progesterone receptor; Binding affinity;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2008 سفارش ترجمه

Glucocorticoid receptor binding: A biphasic dependence on molecular size as revealed by the bilinear LinBiExp model

Keywords: وابستگی; Fluorination; Glucocorticoid; Molecular size; Structure–activity relationship; Binding affinity

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2008 سفارش ترجمه

The role of molecular size in ligand efficiency

Keywords: وابستگی; Ligand efficiency; Fragment based design; Binding affinity

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2007 سفارش ترجمه

Theoretical calculation of the binding free energies for pyruvate dehydrogenase E1 binding with ligands

Keywords: وابستگی; Herbicide; Dehydrogenase; Inhibitor; Binding; Binding affinity; Modeling

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Angiotensin-converting enzyme (ACE) inhibitors have different selectivity for bradykinin binding sites of human somatic ACE

Keywords: وابستگی; ACE; ACE inhibitor; Angiotensin I; Binding affinity; Bradykinin; Cardiovascular disease; HUVEC; Perindopril; Perindoprilat; Selectivity

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Dynamical regulations of protein–ligand bindings at single molecular level

Keywords: وابستگی; Ab, antibody; Ag, antigen; DXT, diffracted X-ray tracking; Fab, fragment antigen binding; mAb, monoclonal Ab; NP, (4-hydroxy-3-nitrophenyl)acetyl; NP-Cap, NP-ε-amino caproicacidSingle-molecular dynamics; X-ray; Binding affinity; Protein-ligand interaction

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Structure–activity relationships of 19-norvitamin D analogs having a fluoroethylidene group at the C-2 position

Keywords: وابستگی; 2-Alkylidene-19-norvitamin D; VDR; Binding affinity; Transcriptional activity; Structure–activity relationships

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Purification method directly influences effectiveness of an epidermal growth factor-coupled targeting agent for noninvasive tumor detection in mice

Keywords: وابستگی; EGF receptor; IRDye 800CW EGF; In-Cell Western assay; Binding affinity; Noninvasive; Whole animal imaging

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Potent and selective agonists of α-melanotropin (αMSH) action at human melanocortin receptor 5; linear analogs of α-melanotropin

Keywords: وابستگی; α-Melanotropin; αMSH; Melanocortin peptide; NDP-αMSH; Melanocortin receptor 5; Agonist; Binding affinity; cAMP accumulation assay; 4,4′-Bip; 4,4′-biphenylalanine; Nal(2′); 2′-naphthylalanine; Oic; octahydroindole-2-COOH; Pip; pipecolic acid; Ti

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

QSAR method for prediction of protein-peptide binding affinity: Application to MHC class I molecule HLA-A*0201

Keywords: وابستگی; HLA-A*0201; Binding affinity; Amino acids property; QSAR; Heuristic method (HM); Support vector machine (SVM)

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Complex-type-dependent scoring functions in protein-protein docking

Keywords: وابستگی; Binding affinity; Scoring function; Protein-protein docking;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Affinity profiling using the peptide microarray technology: A case study

Keywords: وابستگی; Microarray technology; Synthetic peptide arrays; Mass action law; Precision accuracy; Binding affinity;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Novel chiral isoxazole derivatives: Synthesis and pharmacological characterization at human β-adrenergic receptor subtypes

Keywords: وابستگی; Synthesis; Isoxazole derivatives; Hybrid compounds; Human β-adrenergic receptor subtypes; Binding affinity; Efficacy

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Ligand interactions with lactose repressor protein and the repressor-operator complex: The effects of ionization and oligomerization on binding

Keywords: وابستگی; Lactose repressor; Isothermal titration calorimetry; Binding affinity; Allosteric behavior; Inducer; Anti-inducer;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2007 سفارش ترجمه

Novel C2-purine position analogs of nitrobenzylmercaptopurine riboside as human equilibrative nucleoside transporter 1 inhibitors

Keywords: وابستگی; Nucleoside transporter inhibitors; Nitrobenzylmercaptopurine riboside (NBMPR); Analogs; Flow cytometry; Binding affinity; Synthesis; Structure–activity relationship (SAR); Equilibrative nucleoside transporter 1

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2007 سفارش ترجمه

The structure–activity relationship of the series of non-peptide small antagonists for p56lck SH2 domain

Keywords: وابستگی; T-cell inhibition; Non-peptide; Antagonist; Inhibitor; SH2; Binding affinity

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

Interaction energies of nitrofurans with trypanothione reductase and glutathione reductase studied by molecular docking

Keywords: وابستگی; Nitrofurans; Trypanothione reductase; Binding affinity; Docking; Chagas' disease;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2007 سفارش ترجمه

NMR methods for the determination of protein-ligand dissociation constants

Keywords: وابستگی; NMR spectroscopy; Protein-ligand interactions; Binding affinity; Quantitative methods; Drug discovery;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2007 سفارش ترجمه

Why does avian influenza A virus hemagglutinin bind to avian receptor stronger than to human receptor? Ab initio fragment molecular orbital studies

Keywords: وابستگی; Influenza; Hemagglutinin; Neu5Ac-Gal; Ab initio FMO; Binding energy; Binding affinity; Computational chemistry

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2006 سفارش ترجمه

Size effect in thiol and amine binding to small Pt nanoparticles

Keywords: وابستگی; 1-Dodecanethiol; Dodecylamine; Pt nanoparticle; Binding affinity; Methanol oxidation

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2006 سفارش ترجمه

Analysis of interactions of template/primer duplexes with T7 DNA polymerase by oligonucleotide microarray

Keywords: وابستگی; Oligonucleotide microarray; T7 DNA polymerase; Protein–DNA interaction; Binding affinity

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Effect of temperature acclimation on metabolism and hemocyanin binding affinities in two crayfish, Procambarus clarkii and Procambarus zonangulus

Keywords: وابستگی; Crayfish; Procambarus clarkii; Procambarus zonangulus; Temperature; Acclimation; Metabolism; Binding affinity; Hemocyanin

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Complexation and time-dependent accumulation of copper by larval fathead minnows (Pimephales promelas): Implications for modeling toxicity

Keywords: وابستگی; Bioavailability; Binding affinity; Binding-site density; Biotic ligand model

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Structural features of the reprolysin atrolysin C and tissue inhibitors of metalloproteinases (TIMPs) interaction

Keywords: وابستگی; TIMP; Atrolysin C; SVMP; Molecular docking; Molecular dynamics simulation; Binding affinity

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Synthesis of enantiopure Δ2-isoxazoline derivatives and evaluation of their affinity and efficacy profiles at human β-adrenergic receptor subtypes

Keywords: وابستگی; Synthesis; Δ2-Isoxazoline derivatives; Human β-adrenergic receptor subtypes; Binding affinity; Efficacy; Antagonist

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Structural and functional characterization of human microsomal prostaglandin E synthase-1 by computational modeling and site-directed mutagenesis

Keywords: وابستگی; Prostaglandin; PGE2; mPGES-1; Protein structure; Molecular modeling; Mutagenesis; Binding affinity;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Response and function of cutaneous mucosal and serum antibodies in barramundi (Lates calcarifer) acclimated in seawater and freshwater

Keywords: وابستگی; Vaccine; Mucosal antibody; Binding affinity; Salinity; Asian sea bass; Barramundi

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Exo-Dye-based assay for rapid, inexpensive, and sensitive detection of DNA-binding proteins

Keywords: وابستگی; DNA-binding proteins; Exonuclease III protection; SYBR Green I dye; Fluorescence spectroscopy; Binding affinity

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Exploring protein–ligand recognition with Binding MOAD

Keywords: وابستگی; Molecular recognition; Binding affinity; Cavity; Surface area; Protein–ligand database

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

Antagonists of the myelin-associated glycoprotein: A new class of tetrasaccharide mimics

Keywords: وابستگی; Axonal regeneration; Binding affinity; Carbohydrate-binding epitope; Myelin-associated glycoprotein (MAG); Biphenyl; Suzuki coupling; Miyaura boronation

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2006 سفارش ترجمه

QSAR study for a novel series of ortho disubstituted phenoxy analogues of α1-adrenoceptor antagonist WB4101

Keywords: وابستگی; WB4101 analogues; α1-Adrenoreceptor; 5-HT1A receptor; Binding affinity; QSAR

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2006 سفارش ترجمه

Modeling kinase-substrate specificity: implication of the distance between substrate nucleophilic oxygen and attacked phosphorus of ATP analog on binding affinity

Keywords: وابستگی; Kinase-substrate specificity; Distance; Binding affinity; Molecular dynamics simulation;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

An all atom energy based computational protocol for predicting binding affinities of protein–ligand complexes

Keywords: وابستگی; Scoring function; Binding affinity; Protein–ligand complexes; Structure-based drug design; Drug design in silico

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Structure-function relationships of gene delivery vectors in a limited polycation library

Keywords: وابستگی; Nonviral gene delivery; Structure-activity relationships; Polylysine; Cytotoxicity; Binding affinity;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

SPOT synthesis: Reliability of array-based measurement of peptide binding affinity

Keywords: وابستگی; SPOT technology; Synthetic peptide arrays; Binding affinity; Dissociation constant; Effective concentration; Mass action law; Competition;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

QSAR study for a novel series of ortho monosubstituted phenoxy analogues of α1-adrenoceptor antagonist WB4101

Keywords: وابستگی; α1-Antagonist; WB4101; WB4101 Analogues; α1-Adrenergic receptor subtypes; 5-HT1A Serotoninergic receptor; Binding affinity; QSAR analysis

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2005 سفارش ترجمه

LigScore: a novel scoring function for predicting binding affinities

Keywords: وابستگی; LigScore; Binding affinity; Desolvation penalty;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2005 سفارش ترجمه