Keywords: مانع خون مغزی; Aβ; amyloid-β; BBB; blood-brain-barrier; CaMKII; calcium calmodulin kinase II; CFC; contextual fear conditioning test; DAG; diacylglycerol; F3; fibronectin type III module; FGFR; fibroblast growth factor receptor; GABAAR; γ-aminobutyric acid A recept
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Keywords: مانع خون مغزی; BBB; blood-brain-barrier; BM; bone marrow; BM-MSC; bone marrow-derived mesenchymal stem cell; BMP; bone morphogenetic protein; BNP; brain natriuretic protein; CFU; colony forming unit; CNS; central nervous system; CSC; cardiac stem cell; EC; endothelial
Keywords: مانع خون مغزی; BBB; blood-brain-barrier; BDNF; brain-derived neurotrophic factor; BLA; basolateral amygdala; CNS; central nervous system; CMS; chronic mild stress; CRF; corticotropin-releasing factor; CSDS; chronic social defeat stress; Dnmt; DNA methyltransferase; EC
Keywords: مانع خون مغزی; Phytosterols; Stable isotopes; Blood-Brain-Barrier; Brain lipids; Cholesterol metabolism; Plant sterols;
Keywords: مانع خون مغزی; AA; arachidonic acid; Aβ; fibrillar β-amyloid; ACC; acetyl-CoA carboxylase; Akt; protein kinase B; APP; amyloid precursor protein; ASAH2; neutral ceramidase; BA; benzyl alcohol; BBB; blood-brain-barrier; BMI; body mass index; BPM; bis(monoacylglycero)
Keywords: مانع خون مغزی; Brain/plasma-ratio; In vivo; Steady state; Brain penetration; Drug discovery; Loading dose; Rat; 3Rs-benefit; AUC; area under the plasma concentration curve; BBB; blood-brain-barrier; B/P-ratio; brain/plasma-ratio of drug concentration; CNS; central ner
Keywords: مانع خون مغزی; Brain; Neuron; Astrocyte; Blood-brain-barrier; Allan-Herndon-Dudley syndrome;
Keywords: مانع خون مغزی; ASDH; acute subdural hemorrhage; BBB; blood-brain-barrier; CBF; cerebral blood flow; EPO; erythropoietin; EPOR; erythropoietin receptor; HHT; hyperoncotic/hypertonic solution treatment; ICP; intracranial pressure; LDU; Laser-Doppler units; MAP; mean art
Acylated and unacylated ghrelin confer neuroprotection to mesencephalic neurons
Keywords: مانع خون مغزی; AG; acylated; BBB; blood-brain-barrier; CCCP; carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone; GHSR1a; growth hormone secretagogue receptor 1a; GOAT; ghrelin O-acyltransferase; mDA; mesencephalic dopaminergic; NeuN; neuronal nuclei; OCR; oxygen con
Inhibition of Nkcc1 promotes axonal growth and motor recovery in ischemic rats
Keywords: مانع خون مغزی; BBB; blood-brain-barrier; BDA; biotinylated dextran amine; CST; corticospinal tract; DAPI; 4,6-diamino-2-phenyl indole; ET-1; endothelin-1; GABA; Gamma-aminobutyric acid; KCC2; K+-Clâ-co-transporter 2; LSD; least significant difference; MAG; myelin-as
Sodium butyrate exerts protective effect against Parkinson's disease in mice via stimulation of glucagon like peptide-1
Keywords: مانع خون مغزی; Parkinson's disease; Sodium butyrate; Blood-brain-barrier; Apoptosis; GLP-1;
Large amino acid transporter 1 mediated glutamate modified docetaxel-loaded liposomes for glioma targeting
Keywords: مانع خون مغزی; LAT1; Liposomes; Docetaxel; Glioma; Blood-brain-barrier;
Characterization of secretomes from a human blood brain barrier endothelial cells in-vitro model after ischemia by stable isotope labeling with aminoacids in cell culture (SILAC)
Keywords: مانع خون مغزی; Secretome; Silac; Endothelial cells; Ischemic stroke; Biomarkers; Cerebral ischemia; Blood-brain-barrier;
Designing the angiogenic inhibitor for brain tumor via disruption of VEGF and IL17A expression
Keywords: مانع خون مغزی; Glioblastoma; Blood-brain-barrier; IL17A; VEGF; P-gp;
Brain cortical cholesterol metabolism is highly affected by human APP overexpression in mice
Keywords: مانع خون مغزی; Alzheimer's disease; Aβ; Cholesterol; Amyloid precursor protein overexpression; Mouse model; APPSL; AD; Alzheimer's disease; Aβ; amyloid beta; ACAT; Acetyl-CoA acetyltransferases; APP; amyloid precursor protein; ApoB-100; apolipoprotein B-100; ApoE; apo
Analysis of three leakage-correction methods for DSC-based measurement of relative cerebral blood volume with respect to heterogeneity in human gliomas
Keywords: مانع خون مغزی; rCBV; relative cerebral blood volume; K2; permeability related fitting parameter; CA; contrast agent; SVD; singular value decomposition; DSC; dynamic susceptibility contrast; PB; pre-bolus; MTT; mean transit time; BBB; blood-brain-barrier; WM; white mat
An update on the stereoselective synthesis of γ-amino acids
Keywords: مانع خون مغزی; ABO; 2,7,8-trioxabicyclo[3.2.1]octane; Ac; acetyl; ACPECA; 4-aminocyclopent-2-ene-1-carboxylic acid; AHPPA; 4-amino-3-hydroxy-5-phenylpentanoic acid; AMCP; 2-(aminomethyl)-cyclopentanecarboxylic acid; APCH; 2-(1-aminopropyl)cyclohexanecarboxylic acid; APT
Research ReportChanges in the gene expression of estrogen receptors involved in the protective effect of estrogen in rat׳s trumatic brain injury
Keywords: مانع خون مغزی; TBI; traumatic brain injury; BBB; blood-brain-barrier; ER; estrogen receptors; OVX; ovariectomized; PBS; phosphate buffered saline; CNS; central nervous system; DMSO; Dimethyl sulfoxide; EB; Evans blue; TBS; tris-buffered saline; ANOVA; analysis of vari
Improved blood-brain-barrier permeability and tissue distribution following the oral administration of a food-grade formulation of curcumin with fenugreek fibre
Keywords: مانع خون مغزی; Curcumin; Oral bioavailability; Functional food; Blood-brain-barrier; Tissue distribution; Pharmacokinetics;
In vivo delivery of siRNA to the brain by carbosilane dendrimer
Keywords: مانع خون مغزی; HIV infection; Carbosilane dendrimer; siRNA delivery; Brain; Blood-brain-barrier; Central nervous system;
Increased brain bio-distribution and chemical stability and decreased immunogenicity of an engineered variant of GDNF
Keywords: مانع خون مغزی; 6-OHDA; 6-Hydroxy-dopamine; BBB; Blood-brain-barrier; CEX; Cation Exchange chromatography; CHO; Chinese Hamster Ovary; DOPAC; Dihydroxyphenylacetic acid; Dopa; 3,4-dihydroxyphenylalanine; DA; Dopamine; ECM; Extracellular matrix; GDNF; Glial cell line-de
Small synthetic hyaluronan disaccharides afford neuroprotection in brain ischemia-related models
Keywords: مانع خون مغزی; BBB; blood-brain-barrier; CS; chondroitin sulfate; CSPG; chondroitin sulfate proteoglycan; DCFH; dichlorofluorescein; di0S; methyl 2-acetamido-2-deoxy-3-O-(β-d-glucopyranosyluronic acid)-O-sulfo-α-d-glucopyranoside, sodium salt; di4,6S; methyl 2-aceta
Cysteinyl leukotriene receptor (CysLT) antagonists decrease pentylenetetrazol-induced seizures and blood-brain barrier dysfunction
Keywords: مانع خون مغزی; ANOVA; analysis of variance; BBB; blood-brain-barrier; DMSO; dimethyl sulfoxide; EEG; electroencephalography; PBS; phosphate-buffered saline; PGE2; prostaglandin E2; PTZ; pentylenetetrazol; TCA; trichloroacetic acid; TJ; tight junctions; leukotrienes; p
Serotonin transporter protein (SERT) and P-glycoprotein (P-gp) binding activity of montanine and coccinine from three species of Haemanthus L. (Amaryllidaceae)
Keywords: مانع خون مغزی; AChE; acetylcholinesterase; BBB; blood-brain-barrier; BCRP; breast cancer resistance protein; CNS; central nervous system; P-gp; P-glycoprotein; SERT; serotonin transporter protein; SSRI; selective serotonin reuptake inhibitor; Haemanthus; Amaryllidacea
Research ReportEfflux of monoclonal antibodies from rat brain by neonatal Fc receptor, FcRn
Keywords: مانع خون مغزی; FcRn; neonatal Fc receptor; IgG; immunoglobulin G; WT; wild type; Blood-brain-barrier; IgG; FcRn; Efflux; Intracranial; Intranasal;
NMO sera down-regulate AQP4 in human astrocyte and induce cytotoxicity independent of complement
Keywords: مانع خون مغزی; Neuromyelitis optica; Aquaporin 4; Astrocyte; Endothelial cell; Co-culture; Blood-brain-barrier; Cytokine;
Overexpression of HSPA12B protects against cerebral ischemia/reperfusion injury via a PI3K/Akt-dependent mechanism
Keywords: مانع خون مغزی; I/R; ischemia/reperfusion; BBB; Blood-brain-barrier; HSPs; Heat shock proteins; HSPA12B; Heat shock protein A12B; PI3K/Akt; phosphoinositide 3-kinase/protein kinase B; TTC; 2,3,5-triphenyltetrazolium chloride; WM; Wortmannin; Cerebral ischemia/reperfusi
In vivo detection of free radicals in mouse septic encephalopathy using molecular MRI and immuno-spin trapping
Keywords: مانع خون مغزی; anti-DMPO probe; anti-DMPO-biotin-BSA-Gd-DTPA; BBB; blood-brain-barrier; BSA; bovine serum albumin; CLP; cecal ligation and puncture; DMPO; 5,5-dimethyl-1-pyrroline-N-oxide; Gd-DTPA; gadolinium diethylene triamine pentaacetic acid; HNE; 4-hydroxynonenal
The phosphodiesterase-4 inhibitor rolipram protects from ischemic stroke in mice by reducing blood-brain-barrier damage, inflammation and thrombosis
Keywords: مانع خون مغزی; Blood-brain-barrier; Phosphodiesterase inhibitor; Rolipram; Inflammation; Middle cerebral artery occlusion; Edema; Apoptosis; Thrombosis; Cytokines; Stroke;
Analysis of a read-through promoting compound in a severe mouse model of spinal muscular atrophy
Keywords: مانع خون مغزی; SMA; spinal muscular atrophy; SMN; survival motor neuron; CNS; central nervous system; ICV; intracerebral ventricular injection; BBB; blood-brain-barrier; Spinal muscular atrophy (SMA); Survival motor neuron (SMN); Read-through; Aminoglycoside;
Mannitol-facilitated perfusion staining with 2,3,5-triphenyltetrazolium chloride (TTC) for detection of experimental cerebral infarction and biochemical analysis
Keywords: مانع خون مغزی; 2,3,5-Triphenyltetrazolium chloride (TTC); Blood-brain-barrier; Lipopolysaccharide (LPS); Hypoxia-ischemia; Cerebral ischemia; Penumbra;
Hippocampal tissue of patients with refractory temporal lobe epilepsy is associated with astrocyte activation, inflammation, and altered expression of channels and receptors
Keywords: مانع خون مغزی; AQP; aquaporin; BBB; blood-brain-barrier; COX-2; cyclooxegenase-2; CX43; connexin 43; DAPC; dystrophin-associated protein complex; GFAP; glial fibrilary acidic protein; Kir4.1; K+ channel 4.1; mGluR; metabotropic glutamate receptor; NF-κB; nuclear fact
Functional roles of transferrin in the brain
Keywords: مانع خون مغزی; Transferrin; Neuron; Oligodendrocyte; Blood-brain-barrier; Iron; Choroid plexus;
The arcuate nucleus as a circumventricular organ in the mouse
Keywords: مانع خون مغزی; CVO; circumventricular organ; IgGs; immunoglobulins; ME; median eminence; MECA32; rat monoclonal antiserum to a mouse endothelial cell antigen; PV1; plasmalemmal vesicle associated protein 1; vmARC; ventromedial arcuate nucleus; Arcuate nucleus; Blood-b
MK801 blocks hypoxic blood-brain-barrier disruption and leukocyte adhesion
Keywords: مانع خون مغزی; Blood-brain-barrier; Hypoxia; NMDA receptor; Oxidative stress; Stroke; MK801;
Development of fetal brain renin-angiotensin system and hypertension programmed in fetal origins
Keywords: مانع خون مغزی; ACE; angiotensin converting enzyme; ACTH; adrenocorticotropic hormone; Ang; angiotensin; AP; area postrema; AT1R; angiotensin II receptor subtype 1; AT2R; angiotensin II receptor subtype 2; ATIP; AT2R-interacting protein; AVP; arginine vasopressin; BBB; b
Protein therapy for Unverricht-Lundborg disease using cystatin B transduction by TAT-PTD
Keywords: مانع خون مغزی; Progressive myoclonus epilepsy; Unverrricht-Lundborg; Protein therapy; Blood-brain-barrier; Cell-permeable peptide; TAT-PTD;
Bilateral, vascular and perivascular glial upregulation of heat shock protein-27 after repeated epileptic seizures
Keywords: مانع خون مغزی; Epilepsy; Astrocytes; Endothelial cells; Blood-brain-barrier; Oxidative stress; Pentylentetrazole;