Keywords: قطعه مغز; Spreading depression; Brain slice; Excitotoxicity; Metabolic compromise; NMDA receptor; Calcium loading; Neuronal injury; Excitatory postsynaptic potentials;
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Sevoflurane activates hippocampal CA3 kainate receptors (Gluk2) to induce hyperactivity during induction and recovery in a mouse model
Keywords: قطعه مغز; animal model; brain slice; electrophysiology; GluK2; hyperactivity; kainate receptors; mice behaviour; sevoflurane; seizure; volatile anaesthetics;
AMP kinase regulates ligand-gated K-ATP channels in substantia nigra dopamine neurons
Keywords: قطعه مغز; AMPK; AMP-activated protein kinase; EGTA; ethylene glycol tetraacetic acid; HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; K-ATP channel; ATP-sensitive K+ channel; NMDA; N-methyl-d-aspartate; SNC; substantia nigra zona compacta; STN; subthalam
Memantine selectively blocks extrasynaptic NMDA receptors in rat substantia nigra dopamine neurons
Keywords: قطعه مغز; CNQX, 6-cyano-7-nitro-quinoxalone; EPSC, excitatory postsynaptic current; NMDA, N-methyl-d-aspartate; SNC, substantia nigra zona compacta; TTX, tetrodotoxinWhole-cell recording; Brain slice; MK-801; DQP-1105; Synaptic; Extrasynaptic
Basic NeuroscienceStimDuino: An Arduino-based electrophysiological stimulus isolator
Keywords: قطعه مغز; Electrical stimulation; Arduino; Electrophysiology; Brain slice; In vivo;
Interference between field excitatory postsynaptic potentials and simultaneously recorded chronoamperometric l-glutamate currents in mouse hippocampal slices
Keywords: قطعه مغز; Chronoamperometry; Field excitatory postsynaptic potentials; l-Glutamate; Circuit simulation; Brain slice
Co-activation of synaptic and extrasynaptic NMDA receptors by neuronal insults determines cell death in acute brain slice
Keywords: قطعه مغز; Glutamate; Synaptic NMDA receptors; Extrasynaptic NMDA receptors; Excitotoxicity; Brain slice;
Characterization of altered intrinsic excitability in hippocampal CA1 pyramidal cells of the Aβ-overproducing PDAPP mouse
Keywords: قطعه مغز; Alzheimer's disease; Hippocampus; Electrophysiology; Excitability; Brain slice; Action potential;
Effects of the Parkinsonian toxin MPP+ on electrophysiological properties of nigral dopaminergic neurons
Keywords: قطعه مغز; Dopamine; D2 autoreceptors; KATP channels; HCN channels; Brain slice; ACSF; artificial cerebrospinal fluid; ATP; adenosine triphosphate; DA; dopamine; DAT; dopamine transporter; GIRK; G protein-coupled inwardly rectifying potassium channels; HCN; hyperpol
Electrophysiologically identified presynaptic mechanisms underlying amylinergic modulation of area postrema neuronal excitability in rat brain slices
Keywords: قطعه مغز; Area postrema; Amylin; Patch-clamp; Brain slice; Rat
A system for precise temperature control of isolated nervous tissue under optical access: Application to multi-electrode recordings
Keywords: قطعه مغز; Retina; Brain slice; Temperature control; Temperature effects
Excitatory and inhibitory synaptic function in the rostral nucleus of the solitary tract in embryonic rat
Keywords: قطعه مغز; Taste; Solitary tract nucleus; Development; Brain slice; Electrophysiology
Oxygen and glucose deprivation (OGD)-induced spreading depression in the Substantia Nigra
Keywords: قطعه مغز; LT; light transmittance; ÎΨm; mitochondrial membrane potential depolarization; OGD; oxygen-glucose deprivation; Rh123; Rhodamine 123; SD; spreading depression; SN; Substantia Nigra; SNc; Substantia Nigra pars compacta; SNr; Substantia Nigra pars retic
Chronic dopamine depletion augments the functional expression of K-ATP channels in the rat subthalamic nucleus
Keywords: قطعه مغز; STN; subthalamic nucleus; NMDA; N-methyl-d-aspartate; K-ATP; ATP-sensitive K+; 6-OHDA; 6-hydroxydopamine; ANOVA with RM; analysis of variance with repeated measures; ATP-sensitive K+ channel; Subthalamic nucleus; N-Methyl-d-aspartate; Sulfonylurea; Tolbut
Basic NeuroscienceOptogenetic field potential recording in cortical slices
Keywords: قطعه مغز; Field potential recording; Optogenetics; Channelrhodopsin-2; Cerebral cortex; Brain slice; Long-term depression;
Functional test of multidrug transporter activity in hippocampal–neocortical brain slices from epileptic patients
Keywords: قطعه مغز; P-glycoprotein; Multidrug transporters; Multidrug resistance associated protein; Pharmacoresistance; Temporal lobe epilepsy; Brain slice; Calcein
Identification of anti-inflammatory targets for Huntington's disease using a brain slice-based screening assay
Keywords: قطعه مغز; Adenosine; A2A; JNK; IKK; CXCR3; Microglia; Neurodegeneration; Neuroprotection; Biolistics; Brain slice; Drug discovery; Inflammation;
The membrane chamber: A new type of in vitro recording chamber
Keywords: قطعه مغز; In vitro; Brain slice; Recording chamber; Optical imaging; Voltage sensitive dye imaging; Perfusion;
The localization and physiological effects of cannabinoid receptor 1 in the brain stem auditory system of the chick
Keywords: قطعه مغز; cochlear nucleus; synaptic depression; nucleus magnocellularis; brain slice; WIN 55;212–2; calyxABC, avidin-biotin-complex; ACSF, artificial cerebral spinal fluid; ANOVA, analysis of variance; AP, action potential; BSA, bovine serum albumin; CB, cannabino
Persistent ictal-like activity in rat entorhinal/perirhinal cortex following washout of 4-aminopyridine
Keywords: قطعه مغز; Epileptogenesis; Brain slice; Electrophysiology; NMDA; Entorhinal cortex; Perirhinal cortex
Remote switching of temperature, gaseous, and aqueous phase in a low-volume interface chamber for brain slices
Keywords: قطعه مغز; Interface chamber; Hypoxia; Ischemia; Brain slice; Temperature; Electrophysiology; Anoxic depolarization
Δ9-tetrahydrocannabinol is a full agonist at CB1 receptors on GABA neuron axon terminals in the hippocampus
Keywords: قطعه مغز; Marijuana; Brain slice; Learning; Memory; Synaptic plasticity; CannabinoidaCSF, artificial cerebrospinal fluid; APV, D-(−)-2-amino-5-phosphonopentanoic acid; CB1+/+, wildtype C57BL6/J mice; CB1−/−, C57BL6/J mice lacking the gene for the CB1 receptor; CB1R
Inhibition of c-Jun kinase provides neuroprotection in a model of Alzheimer's disease
Keywords: قطعه مغز; JNK; APP; Neurodegeneration; Neuroprotection; Biolistics; Brain slice; Drug discovery;
Influence of CGS 21680, a selective adenosine A2A receptor agonist, on NMDA receptor function and expression in the brain of Huntington's disease mice
Keywords: قطعه مغز; A2A receptor; Huntington's disease; Striatum; Cortex; NMDA receptor; Brain slice
Use of NAD(P)H and flavoprotein autofluorescence transients to probe neuron and astrocyte responses to synaptic activation
Keywords: قطعه مغز; Mitochondria; Brain slice; Metabolism; Glycolysis; Astrocyte; Flavoprotein
Long-term potentiation of intrinsic excitability in trigeminal motoneurons
Keywords: قطعه مغز; TMNs, trigeminal motoneuronsMastication; Long-lasting potentiation; Brain slice
Steroidal and gonadal effects on neural cell proliferation in vitro in an adult songbird
Keywords: قطعه مغز; Ventricular zone; Brain slice; Estrogen; Androgen; Ovary
Trafficking of astrocytic vesicles in hippocampal slices
Keywords: قطعه مغز; ANP, atrial natriuretic peptide; vGlut1, vesicular glutamate transporter 1; MD, maximal displacement; TL, track lengthAstrocyte; Brain slice; Glia; Cytoskeleton; Trafficking
Antioxidant effect of ethyl pyruvate in respiring neonatal cerebrocortical slices after H2O2 stress
Keywords: قطعه مغز; NMR; Ethyl pyruvate; Pyruvate; PBN; Brain slice; Neonatal; Rat; H2O2; Antioxidant
Rotenone reduces Mg2+-dependent block of NMDA currents in substantia nigra dopamine neurons
Keywords: قطعه مغز; Dopamine; Magnesium; Voltage-dependent; N-methyl-d-aspartate; Brain slice; Tyrosine kinase
An ion-pair reversed-phase HPLC method for determination of fresh tissue adenine nucleotides avoiding freeze–thaw degradation of ATP
Keywords: قطعه مغز; ATP; ADP; AMP; Energy charge; HPLC; Nucleotide extraction; Brain slice; Hippocampal
A method for identifying viable and damaged neurons in adult mouse brain slices
Keywords: قطعه مغز; Propidium iodide; Neuronal nuclei (NeuN); Oxygen and glucose deprivation; Brain slice; Immunohistochemistry; Histochemistry; Laser confocal microscopy;
Persistent LTP without triggered protein synthesis
Keywords: قطعه مغز; Hippocampus; Brain slice; Neuronal plasticity; Synapse; Long-term potentiation; L-LTP; Protein synthesis
Diffusion weighted magnetic resonance imaging of neuronal activity in the hippocampal slice model
Keywords: قطعه مغز; fMRI; DWI; Hippocampus; Brain slice; Kainic acid; CNQX; MK-801;
Repeated 4-aminopyridine induced seizures diminish the efficacy of glutamatergic transmission in the neocortex
Keywords: قطعه مغز; Glutamate receptor subunits; Brain slice; Electrophysiology; Co2+ uptake; Histoblot
The physiological role of pre- and postsynaptic GABAB receptors in membrane excitability and synaptic transmission of neurons in the rat's dorsal cortex of the inferior colliculus
Keywords: قطعه مغز; central auditory system; hearing; whole-cell patch clamp recording; brain slice; ion channel; action potentialACSF, artificial cerebrospinal fluid; AHP, after-hyperpolarization; AMPA, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AP, action potent
Adaptation of chicken vestibular nucleus neurons to unilateral vestibular ganglionectomy
Keywords: قطعه مغز; plasticity; brain slice; sodium and potassium channelsACSF, artificial cerebrospinal fluid; AHP, afterhyperpolarization; CNQX, 6-cyano-7-nitroquinoxaline-2, 3-dione; CV, coefficient of variation; DTX, dendrotoxin; H, hatching day; IDS, dendrotoxin-sensiti
5-HT inhibits synaptic transmission in rat subthalamic nucleus neurons in vitro
Keywords: قطعه مغز; presynaptic inhibition; EPSC; IPSC; 5-HT; brain slice; patch clamp; AP5; (±)-2-amino-5-phosphonopentanoic acid; CNQX; 6-cyano-7-nitro-quinoxalone; EPSC; excitatory postsynaptic current; IC50; inhibitory concentration 50%; IPSC; inhibitory postsynaptic cu
Electrophysiological actions of orexins on rat suprachiasmatic neurons in vitro
Keywords: قطعه مغز; Hypocretin; Neurophysiology; Circadian; Arousal; Brain slice
Fructose-1,6-bisphosphate does not preserve ATP in hypoxic–ischemic neonatal cerebrocortical slices
Keywords: قطعه مغز; Fructose-1,6-bisphosphate; FBP; FDP; 31P; 13C; 1H; NMR spectroscopy; Brain slice; Cerebrocortical; Hypoxia; Ischemia; Hydroethidine; Ethidium; Antioxidant; Radicals; ROS; NTP; NDP; ATP; ADP; Nuclear magnetic resonance; Reactive oxygen species
Effects of salicylate application on the spontaneous activity in brain slices of the mouse cochlear nucleus, medial geniculate body and primary auditory cortex
Keywords: قطعه مغز; AC; primary auditory cortex; cACSF; carbogenized artificial cerebrospinal fluid; cACSF-S; carbogenized artificial cerebrospinal fluid with sodium salicylate; CN; cochlear nucleus; IC; inferior colliculus; MGB; medial geniculate body; PO/AH; preoptic anter
Contribution of calpain activation to early stages of hippocampal damage during oxygen-glucose deprivation
Keywords: قطعه مغز; CsA; cyclosporin A; HSD; hypoxic spreading depression; MPTP; mitochondria permeability transition pore; OGD; oxygen-glucose deprivation; Rh 123; Rhodamine 123; ROI; region of interest; ROS; reactive oxygen species; ÎΨm; mitochondrial membrane potentia
Temperature and nitric oxide control spontaneous calcium transients in astrocytes
Keywords: قطعه مغز; Calcium; Astrocyte; Glia; Nitric oxide; Brain slice; Cell culture; Temperature
Rotenone potentiates NMDA currents in substantia nigra dopamine neurons
Keywords: قطعه مغز; Brain slice; Excitotoxicity; Glutamate; Rotenone; Strophanthidin; Substantia nigra pars compacta
Biphasic mechanism of the toxicity induced by 1-methyl-4-phenylpyridinium ion (MPP+) as revealed by dynamic changes in glucose metabolism in rat brain slices
Keywords: قطعه مغز; 1-Methyl-4-phenylpyridinium; Neurotoxicity; GBR 12909; α-Phenyl-N-tert-butylnitrone; [18F]2-fluoro-2-deoxy-d-glucose; Brain slice
Nitrous oxide (N2O) pre- and postsynaptically attenuates NMDA receptor-mediated neurotransmission in the amygdala
Keywords: قطعه مغز; Brain slice; Laser stimulation; Nitrous oxide; NMDA receptor; Patch-clamp; Synaptic transmission
Multiple conductances are modulated by 5-HT receptor subtypes in rat subthalamic nucleus neurons
Keywords: قطعه مغز; 5-HT; subthalamic nucleus; brain slice; patch clamp; burst firingI–V, current-voltage; NMDA, N-methyl-d-aspartate; STN, subthalamic nucleus; TTX, tetrodotoxin
Histamine H1-receptors differentially mediate the action of amylin on hypothalamic neurons in control and in overweight rats
Keywords: قطعه مغز; Body weight regulation; Neonatal overfeeding; Amylin; Histamine H1-receptor antagonist; GABAA-receptor antagonist; Brain slice; Hypothalamus; Single unit activity
Efficient measurement of endogenous neurotransmitters in small localized regions of central nervous systems in vitro with HPLC
Keywords: قطعه مغز; Neurotransmitter measurement; HPLC; Acetylcholine; Ventral motor columns of the spinal cord; preBötzinger Complex; Brain slice; In vitro; Respiratory modulation;
A comparative study of bioradiography in human brain slices and preoperative PET imaging
Keywords: قطعه مغز; Bioradiography; Positron emission tomography (PET); Epilepsy; Brain slice