دانلود مقالات ISI درباره Brca2 + ترجمه فارسی

Risk reducing mastectomy, breast reconstruction and patient satisfaction in Norwegian BRCA1/2 mutation carriers

Keywords: BRCA1; BRCA2; Risk-reducing mastectomy; ReconstructionTRAM, transverse rectus abdominal myocutaneous flap; DIEP, deep inferior epigastric perforator flap; SGAP, superior gluteal artery perforator flap

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Cycling with BRCA2 from DNA repair to mitosis

Keywords: BRCA2; HDR (homology-directed recombination); Replication fork; Spindle assembly checkpoint (SAC); Cell cycle;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Centrosomal BRCA2 is a target protein of membrane type-1 matrix metalloproteinase (MT1-MMP)

Keywords: BRCA2; MT1-MMP; Centrosome;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Deletion of BRCA2 exon 27 causes defects in response to both stalled and collapsed replication forks

Keywords: BRCA2; RAD51; Replication fork stalling; Double strand break; Chromosomal instability

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Dual DNA-binding domains shape the interaction of Brh2 with DNA

Keywords: BRCA2; Rad51; Homologous recombination; DNA repair; DNA binding; DNA annealing; Second-end capture;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Chromosome instability and carcinogenesis: Insights from murine models of human pancreatic cancer associated with BRCA2 inactivation

Keywords: Pancreatic cancer; BRCA2; Genetically engineered mouse model; Chromosomal instability; Hereditary cancer predisposition;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Nicotinamide phosphoribosyltransferase can affect metastatic activity and cell adhesive functions by regulating integrins in breast cancer

Keywords: AMP; adenosine monophosphate; ATP; adenosine triphosphate; BRCA1; breast cancer 1; BRCA2; breast cancer 2; eNAMPT; extracellular nicotinamide phosphoribosyltransferase; ERK; extracellular signal-regulated kinases; iNAMPT; intracellular nicotinamide phosph

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Aurora-A controls cancer cell radio- and chemoresistance via ATM/Chk2-mediated DNA repair networks

Keywords: Aur-A; Aurora-A cDNA-infected cells; Aur-Ai; Aurora-A shRNA-infected cells; BRCA1i; BRCA1 shRNA-infected cells; BRCA2i; BRCA2 shRNA-infected cells; Scr; scrambled shRNA-infected cells; IR; Irradiation; Cis; Cisplatin; KU; KU-55933, the inhibitor of ATM; A

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Targeted Prostate Cancer Screening in BRCA1 and BRCA2 Mutation Carriers: Results from the Initial Screening Round of the IMPACT Study

Keywords: BRCA1; BRCA2; Prostate cancer; Prostate-specific antigen; Targeted screening;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Comprehensive BRCA1 and BRCA2 mutational profile in Lithuania

Keywords: BRCA1; BRCA2; hereditary breast and ovarian cancer; genetic testing; oncogenetics

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Tumor suppressor RecQL5 controls recombination induced by DNA crosslinking agents

Keywords: RecQL5; BRCA2; Fanconi anemia; ICL repair; Rad51 filament; Tumor suppressor;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

High levels of BRC4 induced by a Tet-On 3G system suppress DNA repair and impair cell proliferation in vertebrate cells

Keywords: Homologous recombination; RAD51; BRC4; BRCA2; Tet-On system; DT40 cells;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

BRCA2 inhibition enhances cisplatin-mediated alterations in tumor cell proliferation, metabolism, and metastasis

Keywords: DNA repair; Cisplatin; BRCA2; Drug sensitization; metabolism; metastasis;

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2014 سفارش ترجمه

Frequency of premature menopause in women who carry a BRCA1 or BRCA2 mutation

Keywords: BRCA1; BRCA2; parity; natural menopause; fertility;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

The incidence of endometrial cancer in women with BRCA1 and BRCA2 mutations: An international prospective cohort study

Keywords: BRCA1; BRCA2; Endometrial cancer;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

BRCA2 is epistatic to the RAD51 paralogs in response to DNA damage

Keywords: Recombination; DNA-break Repair; DNA damage; BRCA2; RAD51;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Implications of BRCA1 and BRCA2 mutations for the efficacy of paclitaxel monotherapy in advanced ovarian cancer

Keywords: BRCA1; BRCA2; Taxane; Ovarian cancer; Paclitaxel; Response; Resistance;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Endogenous levels of Rad51 and Brca2 are required for homologous recombination and regulated by homeostatic re-balancing

Keywords: Rad51; Brca2; p53; Homeostatic control; Homologous recombination; siRNA knockdown;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Characteristics of women with ovarian carcinoma who have BRCA1 and BRCA2 mutations not identified by clinical testing

Keywords: BRCA1; BRCA2; BROCA; Genetic testing; Ovarian cancer

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

53BP1 expression in sporadic and inherited ovarian carcinoma: Relationship to genetic status and clinical outcomes

Keywords: 53BP1; BRCA1; BRCA2; Ovarian carcinoma; Homologous recombination; Non-homologous endjoining

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Hereditary Breast/Ovarian Cancer Syndrome

Keywords: BRCA1; BRCA2; Hereditary breast cancer; Hereditary ovarian cancer; Genetic testing; Clinical management;

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2013 سفارش ترجمه

Genetic predisposition to cancer

Keywords: APC; BRCA1; BRCA2; breast cancer; familial polyposis; oncogene; tumour suppressor gene

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

There is no decision to make: Experiences and attitudes toward treatment-focused genetic testing among women diagnosed with ovarian cancer

Keywords: Ovarian cancer; Genetics; BRCA1; BRCA2; Attitudes;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Outcomes of primary surgical cytoreduction in patients with BRCA-associated high-grade serous ovarian carcinoma

Keywords: Ovarian cancer; BRCA; BRCA1; BRCA2; Cytoreduction

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

BRCA1 and BRCA2 germline mutations in Moroccan breast/ovarian cancer families: Novel mutations and unclassified variants

Keywords: Breast cancer; BRCA1; BRCA2; Germline mutations; Morocco

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Tetraploidy in BRCA2 breast tumours

Keywords: Breast cancer; BRCA2; Tetraploidy; Aneuploidy; Diploidy; Luminal; Triple-negative phenotype; Cytokinesis; Flow cytometry

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Identification of the prevalent BRCA1 and BRCA2 mutations in the female population of Puerto Rico

Keywords: BRCA1; BRCA2; hereditary breast and ovarian cancer; Hispanics

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Three novel BRCA1/BRCA2 mutations in breast/ovarian cancer families in Croatia

Keywords: BRCA1; BRCA2; hereditary breast/ovarian cancer; high-resolution melting analysis; quantitative multiplex PCR of short fluorescent fragments

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Clinical characteristics and outcomes of BRCA-associated ovarian cancer: genotype and survival

Keywords: BRCA1; BRCA2; ovarian carcinoma; genetics; cancer

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

BRCA1 and BRCA2 mutations among ovarian cancer patients from Colombia

Keywords: Colombia; Ovarian cancer; Hereditary; BRCA1; BRCA2;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Contribution of epigenetic alteration of BRCA1 and BRCA2 genes in breast carcinomas in Tunisian patients

Keywords: Breast cancer; BRCA1; BRCA2; Methylation; Tunisia

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Tumores primitivos de la trompa de Falopio

Keywords: Trompa de Falopio; Adenocarcinoma; Quimioterapia; Cirugía de las trompas; Mutación cromosómica deletérea; BRCA1; BRCA2

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Filamin-A as a marker and target for DNA damage based cancer therapy

Keywords: DSB; DNA double strand break; SSB; DNA single strand break; ICL; DNA interstrand cross-link; Filamin-A; ABP-280; BRCA2; BRCA1; DNA single strand break; DNA interstrand crosslink; DNA double strand break; Bleomycin; Cisplatin; Biomarker;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Dysfunctional telomeres in human BRCA2 mutated breast tumors and cell lines

Keywords: Breast carcinoma; BRCA2; Telomere sister chromatid exchanges; Interstitial telomeric sequences; Telomere dysfunction-induced foci; Extrachromosomal telomeric repeat DNA;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Tumor suppressor genes and ROS: complex networks of interactions

Keywords: ATM; ataxia telangiectasia mutated protein; BRCA; breast cancer susceptibility gene; CAT; catalase; CDK; cyclin-dependent kinase; FoxO; class O forkhead box transcription factors; GLS2; glutaminase; GPX; glutathione peroxidase; GSH; glutathione; JNK; Jun

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Screening of women at high risk for breast cancer

Keywords: Breast Cancer; Risk; BRCA1; BRCA2

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Peripheral blood DNA methylation detected in the BRCA1 or BRCA2 promoter for sporadic ovarian cancer patients and controls

Keywords: PBCs; peripheral blood cells; QAMA; quantitative analysis of methylated alleles; COSA; breast and ovarian cancer in Auvergne; ARDOC; organized regional screening program association; MGB; minor grove binder; FAM; fluorescein amidite; SEM; standard error t

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Is low-grade serous ovarian cancer part of the tumor spectrum of Hereditary Breast and Ovarian Cancer?

Keywords: Ovarian cancer; Low grade histopathology; BRCA1; BRCA2; Risk assessment; Hereditary breast and ovarian cancer;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Quality of life and health status after prophylactic salpingo-oophorectomy in women who carry a BRCA mutation: A review

Keywords: BRCA1; BRCA2; Prophylactic salpingo-oophrectomy; Surgical menopause

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Elevated radiation-induced γH2AX foci in G2 phase heterozygous BRCA2 fibroblasts

Keywords: BRCA1; BRCA2; Double-strand break repair; Homologous recombination; Ionizing radiation;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Radical fimbriectomy: A reasonable temporary risk-reducing surgery for selected women with a germ line mutation of BRCA 1 or 2 genes? Rationale and preliminary development

Keywords: BRCA1; BRCA2; Prophylactic surgery; Salpingectomy; Fimbriectomy

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Frequencies of BRCA1 and BRCA2 mutations among 1,342 unselected patients with invasive ovarian cancer

Keywords: Ovarian cancer; BRCA1; BRCA2

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Reasons for risk-reducing mastectomy versus MRI-screening in a cohort of women at high hereditary risk of breast cancer

Keywords: BRCA1; MRI; Mastectomy; BRCA2; Surveillance

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Advantage of high-resolution melting curve analysis over conformation-sensitive gel electrophoresis for mutational screening of BRCA1 and BRCA2 genes

Keywords: BRCA1; BRCA2; Mutation screening methods; High-resolution melting analysis (HRMA); Conformation sensitive gel electrophoresis (CSGE); Hereditary breast and ovarian cancer;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

The impact of prophylactic salpingo-oophorectomy on menopausal symptoms and sexual function in women who carry a BRCA mutation

Keywords: Salpingo-oophorectomy; BRCA1; BRCA2; Menopausal symptoms; Sexual functioning;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Valine 1532 of human BRC repeat 4 plays an important role in the interaction between BRCA2 and RAD51

Keywords: BRCA2; RAD51; BRC repeat; Homologous recombination; Canine;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

The underlying mechanism for the PARP and BRCA synthetic lethality: Clearing up the misunderstandings

Keywords: Review; Homologous recombination; Stalled replication fork; DNA double-strand breaks; Poly(ADP-ribose) polymerase; BRCA1; BRCA2; Synthetic lethality; Cancer

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Which individuals undergoing BRACAnalysis need BART testing?

Keywords: BRCA1; BRCA2; gene; genetic testing

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

The Korean Hereditary Breast Cancer (KOHBRA) Study: Protocols and Interim Report

Keywords: BRCA1; BRCA2; hereditary breast neoplasm; mutation; prevalence;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Peptide aptamer mimicking RAD51-binding domain of BRCA2 inhibits DNA damage repair and survival in Trypanosoma brucei

Keywords: Trypanosoma brucei; BRCA2; RAD51; Homologous recombination; DNA repair; Methyl methane sulfonate; Yeast 2-hybrid analysis; Aptamer

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه