Keywords: MNCs; multinucleated cells; TRAP; tartrate-resistant acid phosphatase; RANKL; receptor activator of nuclear factor-κB ligand; M-CSF; macrophage colony stimulating factor; OPG; osteoprotegerin; c-fms; colony-stimulating factor-1 receptor; ERK; extracellul
مقالات ISI (ترجمه نشده)
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Keywords: PTP; protein tyrosine phosphatase; PTK; protein tyrosine kinase; LMW-PTP; low molecular weight protein tyrosine phosphatase; LMW-AP; low molecular weight acid phosphatase; ACP1; gene coding for human LMW-PTP; PTP1B; tyrosine-protein phosphatase non-recept
Keywords: AA; arachidonic acid; ABCA1; adenosine triphosphate-binding cassette transporter A1; ACE-I; angiotensin-converting enzyme inhibitor; ACSL1; acyl-CoA synthase 1; ADMA; asymmetric dimethylarginine; Akt; protein kinase B; Aldo; aldosterone; AMPK; adenosine m
Keywords: PM; particulate matter; O3; ozone; COPD; chronic obstructive pulmonary disease; PM2.5-10; PM with an aerodynamic diameter 2.5-10 μm; PM2.5; PM with an aerodynamic diameter less than 2.5 μm; PM0.1; PM with an aerodynamic diameter less than 0.1 μm
Keywords: Testis; Spermatogenesis; Seminiferous epithelial cycle; FAK; c-Src; c-Yes; Blood-testis barrier; Cell adhesion; Spermiogenesis; Spermiation;
Transforming growth factor-β1 impairs lymph node homing of dendritic cells by downregulating C-type lectin receptor-2 expression
Keywords: c-Src; C-type lectin receptor; Dendritic cell trafficking; Immunosuppressive cytokines; BMDC; bone marrow-derived dendritic cell; Btk; Bruton's tyrosine kinase; CLEC-2; C-type lectin receptor-2; DC; dendritic cell; GM-CSF; granulocyte-macrophage colony-
Positive regulatory role of c-Src-mediated TRIM25 tyrosine phosphorylation on RIG-I ubiquitination and RIG-I-mediated antiviral signaling pathway
Keywords: RIG-I; TRIM25; Interferon; Tyrosine phosphorylation; c-Src; Ubiquitination;
Efficient optimization of pyrazolo[3,4-d]pyrimidines derivatives as c-Src kinase inhibitors in neuroblastoma treatment
Keywords: Neuroblastoma; c-Src; Pyrazolo[3,4-d]pyrimidine;
Identification of N-(5-(phenoxymethyl)-1,3,4-thiadiazol-2-yl)acetamide derivatives as novel protein tyrosine phosphatase epsilon inhibitors exhibiting anti-osteoclastic activity
Keywords: PTP; protein tyrosine phosphatase; c-Src; cellular proto-oncogene tyrosine kinase Src; RANKL; receptor activator of nuclear factor kappa-β ligand; cyt-PTPε; cytosolic PTP epsilon; TRAP; tartrate-resistant acid phosphatase; M-CSF; monocyte colony-stimula
Src family kinases (SFKs) and cell polarity in the testis
Keywords: Src family kinases; c-Src; c-Yes; Testis; Spermatogenesis; Spermatids; Sertoli cells; Cell polarity;
EFhd2/swiprosin-1 regulates LPS-induced macrophage recruitment via enhancing actin polymerization and cell migration
Keywords: EFhd2; Macrophage; Migration; Actin polymerization; Arp2/3 complex; c-Src;
Ca2+ signaling and Src-kinases-controlled cellular functions
Keywords: Ca2+ channels; Cell signaling; Phosphatases; Receptors; Src-family kinases; A23187; 5-(methylamino)-2-({(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl}methyl)-1,3-benzoxazole-4-carboxyli
Connective tissue growth factor (CTGF) from basics to clinics
Keywords: AP1; activator protein 1; ASK1; apoptosis signal-regulating kinase 1; AT1R; angiotensin 2 type 1 receptor; AT2R; angiotensin 2 type 2 receptor; BCL-2; B-cell lymphoma 2; BMP4; bone morphogenic protein 4; BMP7; bone morphogenic protein 7; BMPs; bone morpho
Pyrazolo[3,4-d]pyrimidines-loaded human serum albumin (HSA) nanoparticles: Preparation, characterization and cytotoxicity evaluation against neuroblastoma cell line
Keywords: Neuroblastoma; c-Src; Pyrazolo[3,4-d]pyrimidines; Drug delivery; Drug targeting; Human serum albumin nanoparticles;
The epigenetically-regulated miR-34a targeting c-SRC suppresses RAF/MEK/ERK signaling pathway in K-562 cells
Keywords: miR-34a; c-SRC; Methylation; Epigenetic;
Inhibition of c-Src protects paraquat induced microvascular endothelial injury by modulating caveolin-1 phosphorylation and caveolae mediated transcellular permeability
Keywords: Paraquat; Acute lung injury; Caveolin-1; Vascular endothelial barrier; c-Src;
E2F6 protein levels modulate drug induced apoptosis in cardiomyocytes
Keywords: α-mhc; α-myosin heavy chain; β2-AR; beta-2-adrenergic receptor; Bax; Bcl2 associated protein X; Bcl2; B-cell lymphoma 2; Blm2; bloom syndrome 2 homolog; Bnip3; Bcl2 interacting protein 3; Chk1; checkpoint kinase 1; c-src; proto-oncogene tyrosine protei
Regulation of Na+-K+-ATPase effected high glucose-induced myocardial cell injury through c-Src dependent NADPH oxidase/ROS pathway
Keywords: Na+-K+-ATPase; High glucose; Ouabain; DRm217; ROS; c-Src; NADPH oxidase;
Connexin43 regulates high glucose-induced expression of fibronectin, ICAM-1 and TGF-β1 via Nrf2/ARE pathway in glomerular mesangial cells
Keywords: AGEs; advanced glycation end products; ARE; anti-oxidant response element; Cx43; connexin43; DN; diabetic nephropathy; ECM; extracellular matrix; EMSA; electrophoretic mobility shift assay; FN; fibronectin; GMCs; glomerular messangial cells; GJIC; Gap jun
G2/M cell cycle arrest on HT-29 cancer cells and toxicity assessment of triphenylphosphanegold(I) carbonimidothioates, Ph3PAu[SC(OR)Â =Â NPh], RÂ =Â Me, Et, and iPr, during zebrafish development
Keywords: Annexin V-FITC; Recombinant annexin V conjugated to fluorescein isothiocyanate; APAF-1; Apoptotic protease activating factor 1; ATR; Ataxia telangiectasia and Rad3-related; Bax; Apoptosis regulator; Bcl-2; B-cell lymphoma 2; BIRC-5; Baculoviral inhibitor
Src-family tyrosine kinases and the Ca2Â + signal
Keywords: 5-HT6; serotonin receptor 6; A23187; 5-(methylamino)-2-({(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl}methyl)-1,3-benzoxazole-4-carboxylic acid; ADPR; ADP-ribose; AMPA; α-amino-3-hydr
c-Src tyrosine kinase mediates high glucose-induced endothelin-1 expression
Keywords: Endothelin-1; c-Src; Endothelial dysfunction; Hyperglycemia; Diabetes
Kinetics characterization of c-Src binding to lipid membranes: Switching from labile to persistent binding
Keywords: c-Src; Surface plasmon resonance; Myristoylated proteins; Intrinsically disordered proteins (IDP); Protein dimerization on membranes; Antibody capture; SH4 domains; Cell signaling; c-Src trafficking
Hydroxyflutamide affects connexin 43 via the activation of PI3K/Akt-dependent pathway but has no effect on the crosstalk between PI3K/Akt and ERK1/2 pathways at the Raf-1 kinase level in primary rat Sertoli cells
Keywords: Hydroxyflutamide; Primary Sertoli cells; c-Src; PI3K/Akt; ERK1/2; Cx43; Rat;
The targeted delivery of the c-Src peptide complexed with schizophyllan to macrophages inhibits polymicrobial sepsis and ulcerative colitis in mice
Keywords: Schizophyllan; c-Src; Reactive oxygen species; Sepsis; Colitis;
Reviewc- Src and its role in cystic fibrosis
Keywords: c-Src; Cystic fibrosis; CFTR; Intracellular chloride; IL-1β; PP2; IL1RN;
Chlorogenic acid inhibits hypoxia-induced pulmonary artery smooth muscle cells proliferation via c-Src and Shc/Grb2/ERK2 signaling pathway
Keywords: Chlorogenic acid; c-Src; HIF-1α; Pulmonary artery smooth muscle cell; Proliferation; Hypoxia
Inhibition of c-Src/p38 MAPK pathway ameliorates renal tubular epithelial cells apoptosis in db/db mice
Keywords: Diabetic nephropathy; db/db mice; c-Src; p38 MAPK; Apoptosis;
Recruitment and activation of SLK at the leading edge of migrating cells requires Src family kinase activity and the LIM-only protein 4
Keywords: LMO4; LIM only protein 4; MAPK; mitogen-activated protein kinase; IP; immunoprecipitation; WCL; whole cell lysate; SYF; Src/Yes/Fyn-deficient; Ste20-like kinase; SLK; LMO4; Migration; c-Src; Ldb1;
Embryonal Fyn-associated substrate (EFS) and CASS4: The lesser-known CAS protein family members
Keywords: 5-HT; 5-hydroxytryptamine, serotonin; A549; non-small cell lung cancer cell line; AD; Alzheimer's disease; ADPKD; autosomal dominant polycystic kidney disease; Aire; autoimmune regulator; AP-1; activator protein 1; APP; amyloid precursor protein; AREB6; Z
Interplay between the E2F pathway and β-adrenergic signaling in the pathological hypertrophic response of myocardium
Keywords: β-AR; beta adrenergic receptor; DCM; dilated cardiomyopathy; ERK; extracellular receptor kinase; PDE4D; 5â²3â² cyclic AMP phosphodiesterase 4D; PKA-C; protein kinase A catalytic subunit; Pln; phospholamaban; Rb; retinoblastoma gene product (pocket prot
Novel phosphorylation of PPARγ ameliorates obesity-induced adipose tissue inflammation and improves insulin sensitivity
Keywords: PPARγ; Phosphorylation; c-Src; PTP-1B; Inflammation; Metabolic disorders;
Decreased expression of c-Src in human transitional cell carcinoma
Keywords: c-Src; human transitional cell carcinoma; prognosis
Dysregulated activation of c-Src in gestational trophoblastic disease contributes to its aggressive progression
Keywords: Gestational trophoblastic disease; Hydatidiform mole; Choriocarcinoma; c-Src; Human chorionic gonadotrophin;
Somatic mutational analysis of FAK in breast cancer: A novel gain-of-function mutation due to deletion of exon 33
Keywords: Focal adhesion kinase (FAK); Splicing mutant; Breast cancer; Signal pathway; Migration; c-Src;
Regulation of alkaline ceramidase activity by the c-Src-mediated pathway
Keywords: Ceramidase; Sphingolipid metabolism; c-Src; Lyn; Vanadate
The involvement of FAK and Src in the invasion of cardiomyocytes by Trypanosoma cruzi
Keywords: FAK; c-Src; Trypanosoma cruzi; Cardiomyocytes; Invasion; Signaling pathway;
C-Src-mediated phosphorylation of δ-catenin increases its protein stability and the ability of inducing nuclear distribution of β-catenin
Keywords: δ-Catenin; c-Src; Tyrosine phosphorylation; GSK3; E-cadherin;
T47D breast cancer cells switch from ER/HER to HER/c-Src signaling upon acquiring resistance to the antiestrogen fulvestrant
Keywords: Antiestrogen resistance; Breast cancer; Fulvestrant; HER2; c-Src
Inhibition of c-Src blocks oestrogen-induced apoptosis and restores oestrogen-stimulated growth in long-term oestrogen-deprived breast cancer cells
Keywords: c-Src; Oestrogen; Apoptosis; Epithelial-mesenchymal transition; Breast cancer;
A phase II trial of the Src-kinase inhibitor saracatinib after four cycles of chemotherapy for patients with extensive stage small cell lung cancer: NCCTG trial N-0621
Keywords: Small cell lung cancer; Extensive stage; Maintenance; Saracatinib; C-Src;
c-Src activation through a TrkA and c-Src interaction is essential for cell proliferation and hematological malignancies
Keywords: TrkA; Hematological malignancies; c-Src; PLK-1; Twist-1;
β-Arrestin1-mediated recruitment of c-Src underlies the proliferative action of glucagon-like peptide-1 in pancreatic β INS832/13 cells
Keywords: β-Cell mass; Incretin; GLP-1; c-Src; β-Arrestin; Proliferation;
The cytoskeletal regulatory scaffold protein GIT2 modulates mesenchymal stem cell differentiation and osteoblastogenesis
Keywords: GPCR; G protein-coupled receptor; GRK; GPCR kinase; GIT; GRK-interacting protein; ARF-GAPs; ADP-ribosylation factor GTPase-activating proteins; GEF; guanine nucleotide exchange factor; MSC; mesenchymal stem cell; qCT; quantitative micro-computed tomograph
Impaired c-src activation and motility defects in PEA3-null fibroblasts
Keywords: c-src; PEA3; Adhesion complex; p130Cas; Paxillin; FAK
Ugonin K-stimulated osteogenesis involves estrogen receptor-dependent activation of non-classical Src signaling pathway and classical pathway
Keywords: Ugonin K; Osteogenesis; Estrogen receptor; c-Src; Runx2; Osterix
NNK promotes migration and invasion of lung cancer cells through activation of c-Src/PKCι/FAK loop
Keywords: Lung cancer; Migration; Invasion; PKC iota; c-Src; FAK
Gestrinone inhibits growth of human uterine leiomyoma may relate to activity regulation of ERα, Src and P38 MAPK
Keywords: Gestrinone; Uterine leiomyoma; c-Src; ERα; p38 MAPK
Dasatinib, a multi-kinase inhibitor increased radiation sensitivity by interfering with nuclear localization of epidermal growth factor receptor and by blocking DNA repair pathways
Keywords: Radiation sensitivity; Head and neck cancer; c-Src; EGFR; DNA repair;
Tyrosine phosphorylation of G-protein-coupled-receptor kinase 2 (GRK2) by c-Src modulates its interaction with Gαq
Keywords: GRK2; c-Src; RGS; Gαq