β-Arrestin1-mediated recruitment of c-Src underlies the proliferative action of glucagon-like peptide-1 in pancreatic β INS832/13 cells

► GLP-1 enhances c-Src activity. ► GLP-1 triggers the formation of a signaling complex comprising β-arrestin1 and c-Src. ► β-Arrestin1 and c-Src mediates the action of GLP-1 on β-cell proliferation.