Keywords: نوع گیرنده کانابینوئید 1; acute kidney injury; albuminuria; cannabinoid receptor type 1; cannabinoid receptor type 2; cannabinoids; renal fibrosis;
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Keywords: نوع گیرنده کانابینوئید 1; Cannabinoids; Phytocannabinoids; Endocannabinoids; Therapeutic agents; AEA; Arachidonylethanolamine or Anandamide; 2-AG; 2-arachidonylglycerol; CB1; Cannabinoid receptor type 1; CB2; Cannabinoid receptor type 2; CBD; Cannabidiol; CBG; Cannabigerol; CBL; C
Keywords: نوع گیرنده کانابینوئید 1; AEA; anandamide; BS; behavioral sensitization; CB1; cannabinoid receptor type 1; CB2; cannabinoid receptor type 2; CL; conditioned locomotion; Coc; cocaine; CPP; conditioned place preference; CS+; positive conditioned stimulus; CS-; neutral conditioned st
Keywords: نوع گیرنده کانابینوئید 1; Cannabis; Delta-9-tetrahydrocannabinol; Tolerance; Health; Cannabinoid receptor type 1;
Keywords: نوع گیرنده کانابینوئید 1; Melanoma; Cannabinoid receptor type 1; Tumorigenic role;
Keywords: نوع گیرنده کانابینوئید 1; Avoidance behavior; Response extinction; CB1 receptors; Dopamine D1 receptors; AM404; SDA; step-down inhibitory avoidance; C57BL/6N; C57BL/6NCrl; EBT; exposure based therapy; ECS; endocannabinoid system; D1-CB1â/â; conditional D1-CB1 knock-out mic
Keywords: نوع گیرنده کانابینوئید 1; Cannabinoid receptor type 1; α2-Adrenoceptors; Cannabinoid receptor knock out mice; Medial prefrontal cortex; Locus coeruleus; Tyrosine hydroxylase;
Keywords: نوع گیرنده کانابینوئید 1; ECS; endogenous cannabinoid system; CB1 receptor; cannabinoid receptor type 1; TBI; traumatic brain injury; AEDs; antiepileptic drugs; eCBs; endocannabinoids; PTE; post-traumatic epilepsy; FPI; fluid percussion injury; AEA; anandamide; 2-AG; 2-arachidonoy
Keywords: نوع گیرنده کانابینوئید 1; 2-AG; 2-arachidonoylglycerol; AA; arachidonic acid; ABHD4; α/β-hydrolase domain-containing protein 4; ABHD6; α/β-hydrolase domain-containing protein 6; ABHD12; α/β-hydrolase domain-containing protein 12; AEA; arachidonoylethanolamine; CB1; cannabino
Keywords: نوع گیرنده کانابینوئید 1; 2-AG; 2-arachidonoyl-glycerol; AEA; anandamide; CB1; cannabinoid receptor type 1; CB2; cannabinoid receptor type 2; CNS; central nervous system; DOPAC; 3,4-Dihydroxyphenylacetic acid; DA; dopamine; D2; dopamine receptor subtype 2; ECS; endocannabinoid sys
Keywords: نوع گیرنده کانابینوئید 1; Cannabis; Delta-9-tetrahydrocannabinol; Glutamate signalling; Glutamatergic synaptic transmission; Cannabinoid receptor type 1;
Keywords: نوع گیرنده کانابینوئید 1; Major urinary protein 1; Cannabinoid receptor type 1; Hepatic insulin resistance; Mitochondrial dysfunction
Keywords: نوع گیرنده کانابینوئید 1; AMT; α-methyl-l-tryptophan; BBB; blood-brain barrier; CB1; cannabinoid receptor type 1; CB2; cannabinoid receptor type 2; CNS; central nervous system; FLAIR; fluid-attenuated inversion recovery; Gd-DTPA; gadolinium-diethylenetriaminepentacetate; GFAP;
Keywords: نوع گیرنده کانابینوئید 1; Ghrelin; Growth hormone secretagogue receptor knockout; Cannabinoids; AMPK; Cannabinoid receptor type 1; Ghrelin receptor;
Keywords: نوع گیرنده کانابینوئید 1; AC; adenylyl cyclase; BAT; brown adipose tissue; BMP; bone morphogenetic protein; BST; bed nucleus of the stria terminalis; CB1R; cannabinoid receptor type 1; CNS; central nervous system; CREB; cAMP-response element binding protein; DRN; dorsal raphe nucl
Keywords: نوع گیرنده کانابینوئید 1; 5-HT; 5-Hydroxytryptamine or serotonin; AA-5-HT; N-arachidonoyl-serotonin; ACEA; arachidonoyl 2â²-chloroethylamide; AEA; N-arachidonoylethanolamine; 2-AG; 2-arachidonoylglycerol; AM251; N-(piperidin-1-yl)-5-(4-iodophenyl)-1-(2,4-dichlorophenyl)-4-methyl-
Keywords: نوع گیرنده کانابینوئید 1; ANOVA; analysis of variance; AR; androgen receptor; CB1; cannabinoid receptor type 1; ChIP; chromatin immunoprecipitation; Cnr1; cannabinoid receptor 1; ER; estrogen receptor; EDTA; ethylenediaminetetraacetic acid; IL-1β; interleukin-1 beta; IL-1R; inter
Redox system and phospholipid metabolism in the kidney of hypertensive rats after FAAH inhibitor URB597 administration
Keywords: نوع گیرنده کانابینوئید 1; 2-AG; 2-arachidonoylglycerol; 4-HNE; 4-hydroxynonenal; 8-isoPGF2α; F2 -isoprostanes; 8-OHdG; 8-hydroxy-2'-deoxyguanosine; AA; arachidonic acid; AEA; N-arachidonoylethanolamine, anandamide; AM3506; 5-(4-hydroxyphenyl) pentanesulfonyl fluoride; Bach1; ba
The tamoxifen derivative ridaifen-B is a high affinity selective CB2 receptor inverse agonist exhibiting anti-inflammatory and anti-osteoclastogenic effects
Keywords: نوع گیرنده کانابینوئید 1; Cannabinoid receptors; G-protein coupled receptors; Inverse agonist; Antagonist; Drug action; AC; adenylyl cyclase; CB1R; cannabinoid receptor type 1; CB2R; cannabinoid receptor type 2; CHO; Chinese hamster ovary; CP-55,940; 5-(1,1-dimethylheptyl)-2-[5-hy
Antinociceptive effects of the endogenous cannabinoid peptide agonist VD-hemopressin(β) in mice
Keywords: نوع گیرنده کانابینوئید 1; ANOVA; analysis of variance; AM251; N-(piperidin-1-yl)-5-(4-iodophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3- carboxamide; AM630; 6-iodo-2-methyl-1-[2-(4-morpholinyl)ethyl]-1H-indol-3- yl(4-methoxyphenyl)-methanone; AUC; area under the curve; CB1
Pharmacological inhibition of 2-arachidonoilglycerol hydrolysis enhances memory consolidation in rats through CB2 receptor activation and mTOR signaling modulation
Keywords: نوع گیرنده کانابینوئید 1; JZL184; Rat; Monoacylglycerol lipase (MAGL); Inhibitory avoidance; Fear memory; Behavior; JZL184 [4-[Bis(1,3-benzodioxol-5-yl)hydroxymethyl]-1-piperidinecarboxylic acid 4-nitrophenyl ester]; MAGL inhibitor; SR141716 [5-(4-chlorophenyl)-1-(2,4-dichlorophen
CB1 cannabinoid receptor agonist mouse VD-hemopressin(α) produced supraspinal analgesic activity in the preclinical models of pain
Keywords: نوع گیرنده کانابینوئید 1; AM251; N-(piperidin-1-yl-5-(4-iodophenyl-1-(2,4-dichlorophenyl-4-methyl-1H-pyrazole-3-carboxamide; AM4113; 5-(4-alkylphenyl-1-(2,4-dichlorophenyl-4-methyl-N-(piperidin-1-yl-1H-pyrazole-3-carboxamide; AM630; 6-iodo-2-methyl-1-[2-(4-morpholinylethyl]-1H-ind
Radiosynthesis and evaluation of new PET ligands for peripheral cannabinoid receptor type 1 imaging
Keywords: نوع گیرنده کانابینوئید 1; Cannabinoid receptor type 1; Brown adipose tissue; PET; [11C]Phosgene;
Pharmacological characterization of rat VD-hemopressin(α), an α-hemoglobin-derived peptide exhibiting cannabinoid agonist-like effects in mice
Keywords: نوع گیرنده کانابینوئید 1; ANOVA; analysis of variance; AUC; area under the curve; CB1; cannabinoid receptor type 1; CB2; cannabinoid receptor type 2; CP55,940; (2)-cis-3-[2-hydroxy-4-(1,1-dimethylheptyl)phenyl]-trans-4-(3-hydroxypropyl)cyclohexanol; dNPA; D.NP(N-Me)AFLFQPQRFamide;
The CB1 receptor is required for the establishment of the hyperlocomotor phenotype in developmentally-induced hypothyroidism in mice
Keywords: نوع گیرنده کانابینوئید 1; Hypothyroidism; Cannabinoids; Cannabinoid receptor type 1; Dopamine;
Evaluation of monoacylglycerol lipase as a therapeutic target in a transgenic mouse model of ALS
Keywords: نوع گیرنده کانابینوئید 1; Amyotrophic lateral sclerosis; Endocannabinoid system; KML29; 2-Arachidonoylglycerol; Cannabinoid receptor 1; Monoacylglycerol lipase; Brain-derived neurotrophic factor; 2-AG; 2-arachidonoylglycerol; AA; arachidonic acid; CB1; cannabinoid receptor type 1;
Dorsal hippocampal NMDA receptors mediate the interactive effects of arachidonylcyclopropylamide and MDMA/ecstasy on memory retrieval in rats
Keywords: نوع گیرنده کانابینوئید 1; ACPA; Arachidonylcyclopropylamide; ANOVA; Analysis of variance; CA1; cornus ammonis; CB1; Cannabinoid receptor type 1; CB2; Cannabinoid receptor type 2; CP-55,940; (â)-cis-3-[2-Hydroxy-4-(1,1-dimethylheptyl)phenyl]-trans-4-(3-hydroxypropyl)cyclohexanol;
CXCR4 activation promotes differentiation of human embryonic stem cells to neural stem cells
Keywords: نوع گیرنده کانابینوئید 1; AP; alkaline phosphatase; BDNF; brain-derived neurotrophic factor; cAMP; cyclic adenosine monophosphate; CB1; cannabinoid receptor type 1; CB2; cannabinoid receptor type 2; CNS; central nervous system; CXCR4; CXC chemokine receptor type 4; CXCR7; CXC chem
Pure Î9-tetrahydrocannabivarin and a Cannabis sativa extract with high content in Î9-tetrahydrocannabivarin inhibit nitrite production in murine peritoneal macrophages
Keywords: نوع گیرنده کانابینوئید 1; BSA; albumin bovine serum; CB1; cannabinoid receptor type 1; CB2; cannabinoid receptor type 2; CBC; cannabichromene; CBD; cannabidiol; CBG; cannabigerol; COX-2; cyclooxygenase-2; DAN; 2,3-diaminonaphthalene; DMSO; dimethyl sulfoxide (DMSO); DTT; 1,4-dithi
Tricyclic pyrazoles. Part 8. Synthesis, biological evaluation and modelling of tricyclic pyrazole carboxamides as potential CB2 receptor ligands with antagonist/inverse agonist properties
Keywords: نوع گیرنده کانابینوئید 1; Tricyclic pyrazoles; Synthesis; Cannabinoid receptors; CB2 antagonism; Molecular modelling; Î9-THC; Î9-Tetrahydrocannabinol; 2-AG; 2-Arachidonoylglycerol; CB1; cannabinoid receptor type 1; CB2; cannabinoid receptor type 2; CNS; Central nervous system; T
ReviewAstrocytes: Orchestrating synaptic plasticity?
Keywords: نوع گیرنده کانابینوئید 1; A1R; adenosine A1 receptor; AMPAR; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; CB1R; cannabinoid receptor type 1; GPCR; G protein-coupled receptor; LTD; long-term depression; LTP; long-term potentiation; NMDAR; N-methyl-d-aspartate rec
Piperidinyl thiazole isoxazolines: A new series of highly potent, slowly reversible FAAH inhibitors with analgesic properties
Keywords: نوع گیرنده کانابینوئید 1; FAAH; fatty acid amide hydrolase; AEA; arachidonyl ethanolamide; CB1; cannabinoid receptor type 1; CB2; cannabinoid receptor type 2; CP; cytoplasmic port; ABP; acyl binding pocket; MAC; membrane access channel; D-AMC; decanoyl 7-amino-4-methyl coumarin; A
Intra-visceral insular cortex 2-arachidonoylglycerol, but not N-arachidonoylethanolamide, suppresses acute nausea-induced conditioned gaping in rats
Keywords: نوع گیرنده کانابینوئید 1; 2-AG; 2-arachidonoylglycerol; 5-HT; 5-hydroxytryptamine; AA; arachidonic acid; AEA; N-arachidonoylethanolamide; ANOVA; analysis of variance; CB1; cannabinoid receptor type 1; COX; cyclooxygenase; eCBs; endogenous cannabinoids; FAAH; fatty acid amide hydro
Lipopolysaccharide-induced murine embryonic resorption involves changes in endocannabinoid profiling and alters progesterone secretion and inflammatory response by a CB1-mediated fashion
Keywords: نوع گیرنده کانابینوئید 1; Endocannabinoid system; CB1 knockout; Decidua; Embryotoxicity; 2-AG; 2-arachidonoylglycerol; 2-LG; 2-linoleoyl-sn-glycerol; 2-OG; 2-oleoyl-sn-glycerol; AEA; anandamide; AGly; N-arachidonoylglycine; CB1; cannabinoid receptor type 1; CB1-KO; CB1 receptor kn
The intracerebroventricular injection of rimonabant inhibits systemic lipopolysaccharide-induced lung inflammation
Keywords: نوع گیرنده کانابینوئید 1; ICV; intracerebroventricular; CB1; cannabinoid receptor type 1; LPS; lipopolysaccharide; IV; intravenous; Ppc; pulmonary capillary pressure; TLR4; toll-like receptor 4; IRAK1; interleukin receptor-associated kinase-1; IκBα; inhibitor of nuclear factor o
ReviewReceptome: Interactions between three pain-related receptors or the “Triumvirate” of cannabinoid, opioid and TRPV1 receptors
Keywords: نوع گیرنده کانابینوئید 1; 2-AG; 2-arachidonoylglycerol; 2-AGE; 2-arachidonyl glyceryl ether; AEA; anandamide; AM251; 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-piperidin-1-ylpyrazole-3-carboxamide; CB1; cannabinoid receptor type 1; CB2; cannabinoid receptor type 2; CNS; ce
CB1 cannabinoid receptor antagonist attenuates left ventricular hypertrophy and Akt-mediated cardiac fibrosis in experimental uremia
Keywords: نوع گیرنده کانابینوئید 1; α-SMA; α-smooth muscle actin; ANP; atrial natriuretic peptide; β-MHC; myosin heavy chain beta; BNP; brain natriuretic peptide; BW; body weight; CB1R; cannabinoid receptor type 1; CKD; chronic kidney disease; CMR; cardiac magnetic resonance; CVD; cardio
MAM-2201, a synthetic cannabinoid drug of abuse, suppresses the synaptic input to cerebellar Purkinje cells via activation of presynaptic CB1 receptors
Keywords: نوع گیرنده کانابینوئید 1; Synthetic cannabinoids; MAM-2201; Cannabinoid receptor type 1; Purkinje cell; Cerebellum; Neurotransmitter release; ACSF; artificial cerebrospinal fluid; AM251; N-(piperidin-1-yl)-5-(4-iodophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide;
Effects of CB1 receptor agonism and antagonism on behavioral fear and physiological stress responses in adult intact, ovariectomized, and estradiol-replaced female rats
Keywords: نوع گیرنده کانابینوئید 1; 2-AG; 2-arachidonyl glycerol; ACEA; arachidonyl 2â²-chlorethylamide; AEA; arachidonylethanolamine; ANOVA; analysis of variance; CB1; cannabinoid receptor type 1; DMSO; dimethyl sulfoxide; dPAG; dorsal periaqueductal gray area; E2; 17β-Estradiol; ECS; en
Analgesic tolerance and cross-tolerance to the cannabinoid receptors ligands hemopressin, VD-hemopressin(α) and WIN55,212-2 at the supraspinal level in mice
Keywords: نوع گیرنده کانابینوئید 1; AM251; N-(piperidin-1-yl)-5-(4-iodophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide; AM630; 6-iodo-2-methyl-1-[2-(4-morpholinyl)ethyl]-1H-indol-3-yl(4-methoxyphenyl)-methanone; CB1; cannabinoid receptor type 1; CB2; cannabinoid receptor t
Inhibition of diacylglycerol lipase (DAGL) in the lateral hypothalamus of rats prevents the increase in REMS and food ingestion induced by PAR1 stimulation
Keywords: نوع گیرنده کانابینوئید 1; Protease-activated receptor 1; Cannabinoid receptor type 1; 2-Arachidonoylglycerol; Tetrahydrolipstatin; Food intake; Rapid eye movement sleep2-AG, 2-arachidonoylglycerol; ABHD6, α-β-hydrolase domain 6; AEA, anandamide; CB1R, cannabinoid receptor type 1;
MicroRNA-432 contributes to dopamine cocktail and retinoic acid induced differentiation of human neuroblastoma cells by targeting NESTIN and RCOR1 genes
Keywords: نوع گیرنده کانابینوئید 1; RA; retinoic acid; 3â²-UTR; 3â²-untranslated region; DAPI; 4â²,6-diamidino-2-phenylindole; DC; dopamine cocktail; MECP2; methyl CpG binding protein 2; RCOR1; co-repressor 1 or COREST; TUBB3; beta III-tubilin; NES; NESTIN; CNR1; cannabinoid receptor typ
Endocannabinoids affect innate immunity of Muller glia during HIV-1 Tat cytotoxicity
Keywords: نوع گیرنده کانابینوئید 1; (AEA); N-arachidonoylethanolamide; (2-AG); 2-arachidonoylglycerol; (CB1); cannabinoid receptor type 1; (CB2); cannabinoid receptor type 2; (AM-251); N-(piperidin-1-yl)-5-(4-iodophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3 carboxamide; (AM-630); 6
Update on the pharmacology of selective inhibitors of MAO-A and MAO-B: Focus on modulation of CNS monoamine neurotransmitter release
Keywords: نوع گیرنده کانابینوئید 1; Enzyme active site structure; Presynaptic inhibition; Exocytotic and non-exocytotic release; Neuroprotection; Parkinson's disease; Affective disorders; MAO; monoamine oxidase; MAO-A; monoamine oxidase isoform A; MAO-B; monoamine oxidase isoform B; COMT; c
CB1 and CB2 receptors are novel molecular targets for Tamoxifen and 4OH-Tamoxifen
Keywords: نوع گیرنده کانابینوئید 1; 4OH-Tam; 4OH-Tamoxifen; AC; adenylyl cyclase; CB1R; cannabinoid receptor type 1; CB2R; cannabinoid receptor type 2; CHO; Chinese hamster ovary; CP-55,940; 5-(1,1-dimethylheptyl)-2-[5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]phenol; DMEM; Dulbecco's modific
The effects of fast-off-D2 receptor antagonism on L-DOPA-induced dyskinesia and psychosis in parkinsonian macaques
Keywords: نوع گیرنده کانابینوئید 1; D2; dopamine receptor subtype 2; L-DOPA; L-3,4-dihydroxyphenylalanine; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PD; Parkinson's disease; CB1; cannabinoid receptor type 1; NMDA; N-methyl-d-aspartic acid; PDMA; Parkinsonism During MPTP Administra
Euphol, a tetracyclic triterpene produces antinociceptive effects in inflammatory and neuropathic pain: The involvement of cannabinoid system
Keywords: نوع گیرنده کانابینوئید 1; Euphol; CB1 and CB2 cannabinoid receptor; Cytokines/chemokines; Inflammatory and neuropathic persistent pain; euphol; eupha-8,24-dien-3β-ol; CB; cannabinoid; CB1; cannabinoid receptor type 1; CB2; cannabinoid receptor type 2; AS; antisense; ODN; oligodeo
Facilitation of CB1 receptor-mediated neurotransmission decreases marble burying behavior in mice
Keywords: نوع گیرنده کانابینوئید 1; 2-AG; 2-arachidonoylglycerol; AEA; anandamide; CB1; cannabinoid receptor type 1; CSTC; cortico-striato-thalamo-cortical circuitry; FAAH; fatty acid amide hydrolase; MAGL; monoacylglycerol lipase; MBT; marble burying test; OCD; obsessive-compulsive behav
Role of endocannabinoid and glutamatergic systems in DOI-induced head-twitch response in mice
Keywords: نوع گیرنده کانابینوئید 1; ADHD; Attention-deficit/hyperactivity disorder; AM281; N-(piperidin-1-yl)-5-(4-iodophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide; AM404; N-(4-hydroxyphenyl)arachidonylamide; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate; Anan
Inhibition of endocannabinoid catabolic enzymes elicits anxiolytic-like effects in the marble burying assay
Keywords: نوع گیرنده کانابینوئید 1; 2-AG; 2-Arachidonoylglycerol; AEA; Anandamide, N-arachidonoyl ethanolamine; CB1; Cannabinoid receptor type 1; CB2; Cannabinoid receptor type 2; DZ; Diazepam, 7-chloro-1,3-dihydro-1-methyl-5-phenyl-1,4-benzodiazepin-2(3H)-one; eCB; Endocannabinoid; FAAH; F